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Brian Jason Wainger - Publications

Affiliations: 
2003 Columbia University, New York, NY 
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Huang X, Lee S, Chen K, Kawaguchi R, Wiskow O, Ghosh S, Frost D, Perrault L, Pandey R, Klim JR, Boivin B, Hermawan C, Livak KJ, Geschwind DH, Wainger BJ, et al. Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis. Brain Communications. 6: fcae202. PMID 38911266 DOI: 10.1093/braincomms/fcae202  0.385
2024 Marques C, Held A, Dorfman K, Sung J, Song C, Kavuturu AS, Aguilar C, Russo T, Oakley DH, Albers MW, Hyman BT, Petrucelli L, Lagier-Tourenne C, Wainger BJ. Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia. Acta Neuropathologica. 147: 56. PMID 38478117 DOI: 10.1007/s00401-024-02688-z  0.366
2023 Held A, Adler M, Marques C, Reyes CJ, Kavuturu AS, Quadros ARAA, Ndayambaje IS, Lara E, Ward M, Lagier-Tourenne C, Wainger BJ. iPSC motor neurons, but not other derived cell types, capture gene expression changes in postmortem sporadic ALS motor neurons. Cell Reports. 42: 113046. PMID 37651231 DOI: 10.1016/j.celrep.2023.113046  0.376
2021 Pereira JD, DuBreuil DM, Devlin AC, Held A, Sapir Y, Berezovski E, Hawrot J, Dorfman K, Chander V, Wainger BJ. Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions. Nature Communications. 12: 4744. PMID 34362895 DOI: 10.1038/s41467-021-24776-4  0.331
2021 DuBreuil DM, Chiang BM, Zhu K, Lai X, Flynn P, Sapir Y, Wainger BJ. A high-content platform for physiological profiling and unbiased classification of individual neurons. Cell Reports Methods. 1. PMID 34318289 DOI: 10.1016/j.crmeth.2021.100004  0.306
2020 Wainger BJ, Brown RH. Amyotrophic Lateral Sclerosis: Fuel for the Corticofugal Feud. Annals of Neurology. PMID 32741003 DOI: 10.1002/Ana.25861  0.388
2019 Hawrot J, Imhof S, Wainger BJ. Modeling cell-autonomous motor neuron phenotypes in ALS using iPSCs. Neurobiology of Disease. 104680. PMID 31759135 DOI: 10.1016/J.Nbd.2019.104680  0.392
2019 Moakley D, Koh J, Pereira JD, DuBreuil DM, Devlin AC, Berezovski E, Zhu K, Wainger BJ. Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons. Scientific Reports. 9: 10835. PMID 31346219 DOI: 10.1038/S41598-019-47203-7  0.446
2019 Klim JR, Williams LA, Limone F, Guerra San Juan I, Davis-Dusenbery BN, Mordes DA, Burberry A, Steinbaugh MJ, Gamage KK, Kirchner R, Moccia R, Cassel SH, Chen K, Wainger BJ, Woolf CJ, et al. ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair. Nature Neuroscience. PMID 30643292 DOI: 10.1038/S41593-018-0300-4  0.432
2018 Wainger BJ, Lagier-Tourenne C. Taking on the Elephant in the Tissue Culture Room: iPSC Modeling for Sporadic ALS. Cell Stem Cell. 23: 466-467. PMID 30290176 DOI: 10.1016/J.Stem.2018.09.015  0.347
2018 Aneichyk T, Hendriks WT, Yadav R, Shin D, Gao D, Vaine CA, Collins RL, Domingo A, Currall B, Stortchevoi A, Multhaupt-Buell T, Penney EB, Cruz L, Dhakal J, Brand H, ... ... Wainger BJ, et al. Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly. Cell. 172: 897-909.e21. PMID 29474918 DOI: 10.1016/J.Cell.2018.02.011  0.304
2015 Wainger BJ, Cudkowicz ME. Cortical Hyperexcitability in Amyotrophic Lateral Sclerosis: C9orf72 Repeats. Jama Neurology. 72: 1235-6. PMID 26348624 DOI: 10.1001/Jamaneurol.2015.2197  0.409
2015 Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, et al. Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts. Nature Neuroscience. 18: 17-24. PMID 25420066 DOI: 10.1038/Nn.3886  0.419
2014 Kiskinis E, Sandoe J, Williams LA, Boulting GL, Moccia R, Wainger BJ, Han S, Peng T, Thams S, Mikkilineni S, Mellin C, Merkle FT, Davis-Dusenbery BN, Ziller M, Oakley D, et al. Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1. Cell Stem Cell. 14: 781-95. PMID 24704492 DOI: 10.1016/J.Stem.2014.03.004  0.442
2014 Wainger BJ, Kiskinis E, Mellin C, Wiskow O, Han SS, Sandoe J, Perez NP, Williams LA, Lee S, Boulting G, Berry JD, Brown RH, Cudkowicz ME, Bean BP, Eggan K, et al. Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons. Cell Reports. 7: 1-11. PMID 24703839 DOI: 10.1016/J.Celrep.2014.03.019  0.458
2014 Brenneis C, Kistner K, Puopolo M, Jo S, Roberson D, Sisignano M, Segal D, Cobos EJ, Wainger BJ, Labocha S, Ferreirós N, von Hehn C, Tran J, Geisslinger G, Reeh PW, et al. Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block. British Journal of Pharmacology. 171: 438-51. PMID 24117225 DOI: 10.1111/Bph.12466  0.374
2014 Kiskinis E, Sandoe J, Williams L, Boulting G, Moccia R, Wainger B, Han S, Peng T, Thams S, Mikkilineni S, Mellin C, Merkle F, Davis-Dusenbery B, Ziller M, Oakley D, et al. Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1 Cell Stem Cell. 14: 873. DOI: 10.1016/J.Stem.2014.04.005  0.399
2013 Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ. Bacteria activate sensory neurons that modulate pain and inflammation. Nature. 501: 52-7. PMID 23965627 DOI: 10.1038/Nature12479  0.319
2013 Yang YM, Gupta SK, Kim KJ, Powers BE, Cerqueira A, Wainger BJ, Ngo HD, Rosowski KA, Schein PA, Ackeifi CA, Arvanites AC, Davidow LS, Woolf CJ, Rubin LL. A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS. Cell Stem Cell. 12: 713-26. PMID 23602540 DOI: 10.1016/J.Stem.2013.04.003  0.383
2013 Hanada T, Weitzer S, Mair B, Bernreuther C, Wainger BJ, Ichida J, Hanada R, Orthofer M, Cronin SJ, Komnenovic V, Minis A, Sato F, Mimata H, Yoshimura A, Tamir I, et al. CLP1 links tRNA metabolism to progressive motor-neuron loss. Nature. 495: 474-80. PMID 23474986 DOI: 10.1038/Nature11923  0.379
2011 Son EY, Ichida JK, Wainger BJ, Toma JS, Rafuse VF, Woolf CJ, Eggan K. Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell. 9: 205-18. PMID 21852222 DOI: 10.1016/J.Stem.2011.07.014  0.434
2011 Boulting GL, Kiskinis E, Croft GF, Amoroso MW, Oakley DH, Wainger BJ, Williams DJ, Kahler DJ, Yamaki M, Davidow L, Rodolfa CT, Dimos JT, Mikkilineni S, MacDermott AB, Woolf CJ, et al. A functionally characterized test set of human induced pluripotent stem cells. Nature Biotechnology. 29: 279-86. PMID 21293464 DOI: 10.1038/Nbt.1783  0.311
2004 Santoro B, Wainger BJ, Siegelbaum SA. Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10750-62. PMID 15564593 DOI: 10.1523/Jneurosci.3300-04.2004  0.538
2001 Wainger BJ, DeGennaro M, Santoro B, Siegelbaum SA, Tibbs GR. Molecular mechanism of cAMP modulation of HCN pacemaker channels. Nature. 411: 805-10. PMID 11459060 DOI: 10.1038/35081088  0.492
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