Stefano Pluchino - Publications

Affiliations: 
Department of Clinical Neurosciences University of Cambridge, Cambridge, England, United Kingdom 

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Vecchiarelli HA, Bisht K, Sharma K, Weiser Novak S, Traetta ME, Garcia-Segura ME, St-Pierre MK, Savage JC, Willis C, Picard K, Bordeleau M, Vernoux N, Khakpour M, Garg R, Loewen SM, ... ... Pluchino S, et al. Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2. Biorxiv : the Preprint Server For Biology. PMID 39463930 DOI: 10.1101/2024.10.15.618087  0.705
2024 Ionescu RB, Nicaise AM, Reisz JA, Williams EC, Prasad P, Willis CM, Simões-Abade MBC, Sbarro L, Dzieciatkowska M, Stephenson D, Suarez Cubero M, Rizzi S, Pirvan L, Peruzzotti-Jametti L, Fossati V, ... ... Pluchino S, et al. Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis. Cell Stem Cell. PMID 39437792 DOI: 10.1016/j.stem.2024.09.014  0.774
2023 Leone MA, Gelati M, Profico DC, Gobbi C, Pravatà E, Copetti M, Conti C, Abate L, Amoruso L, Apollo F, Balzano RF, Bicchi I, Carella M, Ciampini A, Colosimo C, ... ... Pluchino S, et al. Phase I clinical trial of intracerebroventricular transplantation of allogeneic neural stem cells in people with progressive multiple sclerosis. Cell Stem Cell. PMID 38016468 DOI: 10.1016/j.stem.2023.11.001  0.365
2023 Hermann DM, Peruzzotti-Jametti L, Giebel B, Pluchino S. Extracellular vesicles set the stage for brain plasticity and recovery by multimodal signalling. Brain : a Journal of Neurology. PMID 37768167 DOI: 10.1093/brain/awad332  0.372
2023 Fossati V, Peruzzotti-Jametti L, Pluchino S. A neural stem-cell treatment for progressive multiple sclerosis. Nature Medicine. 29: 27-28. PMID 36639562 DOI: 10.1038/s41591-022-02164-9  0.41
2022 Peruzzotti-Jametti L, Pluchino S. Therapy with mesenchymal stem cell transplantation in multiple sclerosis ready for prime time: Commentary. Multiple Sclerosis (Houndmills, Basingstoke, England). 28: 1328-1329. PMID 35786043 DOI: 10.1177/13524585221097958  0.364
2022 Willis CM, Nicaise AM, Krzak G, Ionescu RB, Pappa V, D'Angelo A, Agarwal R, Repollés-de-Dalmau M, Peruzzotti-Jametti L, Pluchino S. Soluble factors influencing the neural stem cell niche in brain physiology, inflammation, and aging. Experimental Neurology. 114124. PMID 35644426 DOI: 10.1016/j.expneurol.2022.114124  0.802
2021 Nicaise AM, D'Angelo A, Ionescu RB, Krzak G, Willis CM, Pluchino S. The role of neural stem cells in regulating glial scar formation and repair. Cell and Tissue Research. PMID 34820704 DOI: 10.1007/s00441-021-03554-0  0.802
2021 Smith JA, Nicaise AM, Ionescu RB, Hamel R, Peruzzotti-Jametti L, Pluchino S. Stem Cell Therapies for Progressive Multiple Sclerosis. Frontiers in Cell and Developmental Biology. 9: 696434. PMID 34307372 DOI: 10.3389/fcell.2021.696434  0.81
2021 Peruzzotti-Jametti L, Willis CM, Hamel R, Krzak G, Pluchino S. Metabolic Control of Smoldering Neuroinflammation. Frontiers in Immunology. 12: 705920. PMID 34249016 DOI: 10.3389/fimmu.2021.705920  0.727
2021 Peruzzotti-Jametti L, Bernstock JD, Willis CM, Manferrari G, Rogall R, Fernandez-Vizarra E, Williamson JC, Braga A, van den Bosch A, Leonardi T, Krzak G, Kittel Á, Benincá C, Vicario N, Tan S, ... ... Pluchino S, et al. Neural stem cells traffic functional mitochondria via extracellular vesicles. Plos Biology. 19: e3001166. PMID 33826607 DOI: 10.1371/journal.pbio.3001166  0.772
2021 Pluchino S, Nicaise AM. NSCs: Sentinel Cells of the Brain. Cell Stem Cell. 28: 177-179. PMID 33545074 DOI: 10.1016/j.stem.2020.11.016  0.809
2021 Pluchino S, Nicaise AM. NSCs: Sentinel Cells of the Brain Cell Stem Cell. 28: 177-179. DOI: 10.1016/j.stem.2020.11.016  0.78
2020 Krzak G, Willis CM, Smith JA, Pluchino S, Peruzzotti-Jametti L. Succinate Receptor 1: An Emerging Regulator of Myeloid Cell Function in Inflammation. Trends in Immunology. PMID 33279412 DOI: 10.1016/j.it.2020.11.004  0.757
2020 Willis CM, Nicaise AM, Hamel R, Pappa V, Peruzzotti-Jametti L, Pluchino S. Harnessing the Neural Stem Cell Secretome for Regenerative Neuroimmunology. Frontiers in Cellular Neuroscience. 14: 590960. PMID 33250716 DOI: 10.3389/fncel.2020.590960  0.798
2020 Braga A, Bandiera S, Verheyen J, Hamel R, Rutigliani C, Edenhofer F, Smith JA, Pluchino S. Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32877696 DOI: 10.1016/J.Ymthe.2020.08.001  0.423
2020 Nicaise AM, Willis CM, Crocker SJ, Pluchino S. Stem Cells of the Aging Brain. Frontiers in Aging Neuroscience. 12: 247. PMID 32848716 DOI: 10.3389/Fnagi.2020.00247  0.785
2020 Sullivan GM, Knutsen AK, Peruzzotti-Jametti L, Korotcov A, Bosomtwi A, Dardzinski BJ, Bernstock JD, Rizzi S, Edenhofer F, Pluchino S, Armstrong RC. Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits. Acta Neuropathologica Communications. 8: 84. PMID 32517808 DOI: 10.1186/S40478-020-00960-3  0.437
2020 Pluchino S, Smith JA, Peruzzotti-Jametti L. Promises and Limitations of Neural Stem Cell Therapies for Progressive Multiple Sclerosis. Trends in Molecular Medicine. PMID 32448751 DOI: 10.1016/J.Molmed.2020.04.005  0.452
2020 Thiry L, Hamel R, Pluchino S, Durcan T, Stifani S. Characterization of Human iPSC-derived Spinal Motor Neurons by Single-cell RNA Sequencing. Neuroscience. PMID 32380268 DOI: 10.1016/J.Neuroscience.2020.04.041  0.395
2020 Pluchino S, Willis C. Intrinsic antiviral immunity drives neurodegeneration in Alzheimer disease. The Journal of Clinical Investigation. PMID 32149728 DOI: 10.1172/Jci135906  0.711
2020 Marchetti B, Tirolo C, L'Episcopo F, Caniglia S, Testa N, Smith JA, Pluchino S, Serapide MF. Parkinson's disease, aging and adult neurogenesis: Wnt/β-catenin signalling as the key to unlock the mystery of endogenous brain repair. Aging Cell. e13101. PMID 32050297 DOI: 10.1111/Acel.13101  0.431
2019 Willis CM, Nicaise AM, Peruzzotti-Jametti L, Pluchino S. The neural stem cell secretome and its role in brain repair. Brain Research. 146615. PMID 31863730 DOI: 10.1016/J.Brainres.2019.146615  0.804
2019 Conejos-Sánchez I, Gallon E, Niño-Pariente A, Smith JA, De la Fuente AG, Di Canio L, Pluchino S, Franklin RJM, Vicent MJ. Polyornithine-based polyplexes to boost effective gene silencing in CNS disorders. Nanoscale. PMID 31840717 DOI: 10.1039/C9Nr06187H  0.357
2019 Bernstock JD, Peruzzotti-Jametti L, Leonardi T, Vicario N, Ye D, Lee YJ, Maric D, Johnson KR, Mou Y, Van Den Bosch A, Winterbone M, Friedman GK, Franklin RJM, Hallenbeck JM, Pluchino S. SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke. Ebiomedicine. PMID 30905846 DOI: 10.1016/J.Ebiom.2019.03.035  0.498
2019 Falcone C, Santo M, Liuzzi G, Cannizzaro N, Grudina C, Valencic E, Peruzzotti-Jametti L, Pluchino S, Mallamaci A. Foxg1 Antagonizes Neocortical Stem Cell Progression to Astrogenesis. Cerebral Cortex (New York, N.Y. : 1991). PMID 30821834 DOI: 10.1093/Cercor/Bhz031  0.465
2018 Peruzzotti-Jametti L, Pluchino S. Targeting Mitochondrial Metabolism in Neuroinflammation: Towards a Therapy for Progressive Multiple Sclerosis. Trends in Molecular Medicine. 24: 838-855. PMID 30100517 DOI: 10.1016/J.Molmed.2018.07.007  0.394
2018 L'Episcopo F, Tirolo C, Peruzzotti-Jametti L, Serapide MF, Testa N, Caniglia S, Balzarotti B, Pluchino S, Marchetti B. Neural Stem Cell Grafts Promote Astroglia-driven Neurorestoration in the Aged Parkinsonian Brain via Wnt/β-catenin Signalling. Stem Cells (Dayton, Ohio). PMID 29575325 DOI: 10.1002/Stem.2827  0.442
2018 Smith JA, Braga A, Verheyen J, Basilico S, Bandiera S, Alfaro-Cervello C, Peruzzotti-Jametti L, Shu D, Haque F, Guo P, Pluchino S. RNA Nanotherapeutics for the Amelioration of Astroglial Reactivity. Molecular Therapy. Nucleic Acids. 10: 103-121. PMID 29499926 DOI: 10.1016/J.Omtn.2017.11.008  0.389
2018 L'Episcopo F, Tirolo C, Serapide MF, Caniglia S, Testa N, Leggio L, Vivarelli S, Iraci N, Pluchino S, Marchetti B. Microglia Polarization, Gene-Environment Interactions and Wnt/β-Catenin Signaling: Emerging Roles of Glia-Neuron and Glia-Stem/Neuroprogenitor Crosstalk for Dopaminergic Neurorestoration in Aged Parkinsonian Brain. Frontiers in Aging Neuroscience. 10: 12. PMID 29483868 DOI: 10.3389/Fnagi.2018.00012  0.402
2018 Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CK, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, ... ... Pluchino S, et al. Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation. Cell Stem Cell. PMID 29478844 DOI: 10.1016/J.Stem.2018.01.020  0.522
2018 Mauri E, Sacchetti A, Vicario N, Peruzzotti-Jametti L, Rossi F, Pluchino S. Evaluation of RGD functionalization in hybrid hydrogels as 3D neural stem cell culture systems. Biomaterials Science. PMID 29368775 DOI: 10.1039/C7Bm01056G  0.461
2018 Fuster-Matanzo A, Manferrari G, Marchetti B, Pluchino S. Wnt3a promotes pro-angiogenic features in macrophages in vitro: Implications for stroke pathology. Experimental Biology and Medicine (Maywood, N.J.). 243: 22-28. PMID 29199847 DOI: 10.1177/1535370217746392  0.354
2017 Bernstock JD, Yang W, Ye DG, Shen Y, Pluchino S, Lee YJ, Hallenbeck JM, Paschen W. SUMOylation in brain ischemia: Patterns, targets, and translational implications. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17742260. PMID 29148315 DOI: 10.1177/0271678X17742260  0.356
2017 Huang B, Jiang XC, Zhang TY, Hu YL, Tabata Y, Chen Z, Pluchino S, Gao JQ. Peptide Modified Mesenchymal Stem Cells as Targeting Delivery System Transfected with MiR-133b for the Treatment of Cerebral Ischemia. International Journal of Pharmaceutics. PMID 28827201 DOI: 10.1016/J.Ijpharm.2017.08.073  0.45
2017 Bernstock JD, Ye D, Gessler FA, Lee YJ, Peruzzotti-Jametti L, Baumgarten P, Johnson KR, Maric D, Yang W, Kögel D, Pluchino S, Hallenbeck JM. Topotecan is a potent inhibitor of SUMOylation in glioblastoma multiforme and alters both cellular replication and metabolic programming. Scientific Reports. 7: 7425. PMID 28785061 DOI: 10.1038/S41598-017-07631-9  0.344
2017 Ballini A, Scacco S, Coletti D, Pluchino S, Tatullo M. Mesenchymal Stem Cells as Promoters, Enhancers, and Playmakers of the Translational Regenerative Medicine. Stem Cells International. 2017: 3292810. PMID 28740512 DOI: 10.1155/2017/3292810  0.498
2017 Iraci N, Gaude E, Leonardi T, Costa ASH, Cossetti C, Peruzzotti-Jametti L, Bernstock JD, Saini HK, Gelati M, Vescovi AL, Bastos C, Faria N, Occhipinti LG, Enright AJ, Frezza C, ... Pluchino S, et al. Extracellular vesicles are independent metabolic units with asparaginase activity. Nature Chemical Biology. PMID 28671681 DOI: 10.1038/Nchembio.2422  0.386
2017 Bernstock JD, Peruzzotti-Jametti L, Ye D, Gessler FA, Maric D, Vicario N, Lee YJ, Pluchino S, Hallenbeck JM. Neural stem cell transplantation in ischemic stroke: A role for preconditioning and cellular engineering. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17700432. PMID 28303738 DOI: 10.1177/0271678X17700432  0.416
2016 Volpe G, Bernstock JD, Peruzzotti-Jametti L, Pluchino S. Modulation of host immune responses following non-hematopoietic stem cell transplantation: Translational implications in progressive multiple sclerosis. Journal of Neuroimmunology. PMID 28034466 DOI: 10.1016/J.Jneuroim.2016.12.005  0.484
2016 Pluchino S, Peruzzotti-Jametti L. Interleukin-4 induced 1 (IL4I1) promotes central nervous system remyelination. Brain : a Journal of Neurology. 139: 3052-3054. PMID 27913403 DOI: 10.1093/Brain/Aww266  0.428
2016 Drago D, Basso V, Gaude E, Volpe G, Peruzzotti-Jametti L, Bachi A, Musco G, Andolfo A, Frezza C, Mondino A, Pluchino S. Metabolic determinants of the immune modulatory function of neural stem cells. Journal of Neuroinflammation. 13: 232. PMID 27590826 DOI: 10.1186/S12974-016-0667-7  0.526
2016 Gagliano N, Celesti G, Tacchini L, Pluchino S, Sforza C, Rasile M, Valerio V, Laghi L, Conte V, Procacci P. Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma: Characterization in a 3D-cell culture model. World Journal of Gastroenterology. 22: 4466-83. PMID 27182158 DOI: 10.3748/Wjg.V22.I18.4466  0.309
2016 Iraci N, Leonardi T, Gessler F, Vega B, Pluchino S. Focus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane Vesicles. International Journal of Molecular Sciences. 17: 171. PMID 26861302 DOI: 10.3390/Ijms17020171  0.404
2015 Lener T, Gimona M, Aigner L, Börger V, Buzas E, Camussi G, Chaput N, Chatterjee D, Court FA, Del Portillo HA, O'Driscoll L, Fais S, Falcon-Perez JM, Felderhoff-Mueser U, Fraile L, ... ... Pluchino S, et al. Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. Journal of Extracellular Vesicles. 4: 30087. PMID 26725829 DOI: 10.3402/Jev.V4.30087  0.376
2015 Fuster-Matanzo A, Gessler F, Leonardi T, Iraci N, Pluchino S. Acellular approaches for regenerative medicine: on the verge of clinical trials with extracellular membrane vesicles? Stem Cell Research & Therapy. 6: 227. PMID 26631254 DOI: 10.1186/S13287-015-0232-9  0.387
2015 Ossola B, Zhao C, Compston A, Pluchino S, Franklin RJ, Spillantini MG. Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation. Glia. PMID 26576485 DOI: 10.1002/Glia.22940  0.321
2015 Tambalo S, Peruzzotti-Jametti L, Rigolio R, Fiorini S, Bontempi P, Mallucci G, Balzarotti B, Marmiroli P, Sbarbati A, Cavaletti G, Pluchino S, Marzola P. Functional magnetic resonance imaging of rats with experimental autoimmune encephalomyelitis reveals brain cortex remodeling Journal of Neuroscience. 35: 10088-10100. PMID 26157006 DOI: 10.1523/Jneurosci.0540-15.2015  0.355
2015 Tannahill GM, Iraci N, Gaude E, Frezza C, Pluchino S. Metabolic reprograming of mononuclear phagocytes in progressive multiple sclerosis. Frontiers in Immunology. 6: 106. PMID 25814990 DOI: 10.3389/Fimmu.2015.00106  0.368
2015 Mallucci G, Peruzzotti-Jametti L, Bernstock JD, Pluchino S. The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis. Progress in Neurobiology. 127: 1-22. PMID 25802011 DOI: 10.1016/J.Pneurobio.2015.02.003  0.413
2014 Hermann DM, Peruzzotti-Jametti L, Schlechter J, Bernstock JD, Doeppner TR, Pluchino S. Neural precursor cells in the ischemic brain - integration, cellular crosstalk, and consequences for stroke recovery. Frontiers in Cellular Neuroscience. 8: 291. PMID 25278840 DOI: 10.3389/Fncel.2014.00291  0.428
2014 Cossetti C, Iraci N, Mercer TR, Leonardi T, Alpi E, Drago D, Alfaro-Cervello C, Saini HK, Davis MP, Schaeffer J, Vega B, Stefanini M, Zhao C, Muller W, Garcia-Verdugo JM, ... ... Pluchino S, et al. Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells. Molecular Cell. 56: 193-204. PMID 25242146 DOI: 10.1016/J.Molcel.2014.08.020  0.455
2014 Smith JA, Leonardi T, Huang B, Iraci N, Vega B, Pluchino S. Extracellular vesicles and their synthetic analogues in aging and age-associated brain diseases. Biogerontology. 16: 147-85. PMID 24973266 DOI: 10.1007/S10522-014-9510-7  0.433
2014 Donegà M, Giusto E, Cossetti C, Schaeffer J, Pluchino S. Systemic injection of neural stem/progenitor cells in mice with chronic EAE. Journal of Visualized Experiments : Jove. PMID 24798882 DOI: 10.3791/51154  0.569
2014 Peruzzotti-Jametti L, Donegá M, Giusto E, Mallucci G, Marchetti B, Pluchino S. The role of the immune system in central nervous system plasticity after acute injury. Neuroscience. 283: 210-221. PMID 24785677 DOI: 10.1016/J.Neuroscience.2014.04.036  0.393
2014 L'Episcopo F, Tirolo C, Testa N, Caniglia S, Morale MC, Serapide MF, Pluchino S, Marchetti B. Wnt/β-catenin signaling is required to rescue midbrain dopaminergic progenitors and promote neurorepair in ageing mouse model of Parkinson's disease. Stem Cells (Dayton, Ohio). 32: 2147-63. PMID 24648001 DOI: 10.1002/Stem.1708  0.359
2014 L'Episcopo F, Tirolo C, Caniglia S, Testa N, Morale MC, Serapide MF, Pluchino S, Marchetti B. Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease. Journal of Molecular Cell Biology. 6: 13-26. PMID 24431301 DOI: 10.1093/Jmcb/Mjt053  0.375
2014 Giusto E, Donegà M, Cossetti C, Pluchino S. Neuro-immune interactions of neural stem cell transplants: from animal disease models to human trials. Experimental Neurology. 260: 19-32. PMID 23507035 DOI: 10.1016/J.Expneurol.2013.03.009  0.587
2014 Peruzzotti-jametti L, Mallucci G, Tannahill G, Huang B, Lakes YB, Giusto E, Donega' M, Balzarotti B, Edenhofer F, Pluchino S. Injection of next-generation directly-induced neural stem cells (iNSCs) induces recovery in a mouse model of multiple sclerosis Journal of Neuroimmunology. 275: 193. DOI: 10.1016/J.Jneuroim.2014.08.520  0.478
2014 Iraci N, Cossetti C, Mercer T, Leonardi T, Alpi E, Drago D, Alfaro-cervello C, Saini H, Davis M, Schaeffer J, Muller W, Garcia-verdugo JM, Mathivanan S, Bachi A, Enright A, ... ... Pluchino S, et al. Extracellular vesicles from neural stem cells transfer the IFN-γ/IFNGR1 complex to activate Stat1-dependent signalling in target cells Journal of Neuroimmunology. 275: 190-191. DOI: 10.1016/J.Jneuroim.2014.08.513  0.442
2013 Pluchino S, Peruzzotti-Jametti L. Rewiring the ischaemic brain with human-induced pluripotent stem cell-derived cortical neurons. Brain : a Journal of Neurology. 136: 3525-7. PMID 24335051 DOI: 10.1093/Brain/Awt330  0.509
2013 Drago D, Cossetti C, Iraci N, Gaude E, Musco G, Bachi A, Pluchino S. The stem cell secretome and its role in brain repair. Biochimie. 95: 2271-85. PMID 23827856 DOI: 10.1016/J.Biochi.2013.06.020  0.601
2013 Pluchino S, Cossetti C. How stem cells speak with host immune cells in inflammatory brain diseases. Glia. 61: 1379-401. PMID 23633288 DOI: 10.1002/Glia.22500  0.593
2013 Marchetti B, L'Episcopo F, Morale MC, Tirolo C, Testa N, Caniglia S, Serapide MF, Pluchino S. Uncovering novel actors in astrocyte-neuron crosstalk in Parkinson's disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repair. The European Journal of Neuroscience. 37: 1550-63. PMID 23461676 DOI: 10.1111/Ejn.12166  0.396
2013 L'Episcopo F, Tirolo C, Testa N, Caniglia S, Morale MC, Impagnatiello F, Pluchino S, Marchetti B. Aging-induced Nrf2-ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1462-85. PMID 23345222 DOI: 10.1523/Jneurosci.3206-12.2013  0.371
2013 Marchetti B, Pluchino S. Wnt your brain be inflamed? Yes, it Wnt! Trends in Molecular Medicine. 19: 144-56. PMID 23312954 DOI: 10.1016/J.Molmed.2012.12.001  0.472
2012 Cossetti C, Smith JA, Iraci N, Leonardi T, Alfaro-Cervello C, Pluchino S. Extracellular membrane vesicles and immune regulation in the brain. Frontiers in Physiology. 3: 117. PMID 22557978 DOI: 10.3389/Fphys.2012.00117  0.436
2012 L'Episcopo F, Tirolo C, Testa N, Caniglia S, Morale MC, Deleidi M, Serapide MF, Pluchino S, Marchetti B. Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between inflammatory and Wnt/β-catenin signaling pathways: functional consequences for neuroprotection and repair. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2062-85. PMID 22323720 DOI: 10.1523/Jneurosci.5259-11.2012  0.333
2012 Cossetti C, Alfaro-Cervello C, Donegà M, Tyzack G, Pluchino S. New perspectives of tissue remodelling with neural stem and progenitor cell-based therapies. Cell and Tissue Research. 349: 321-9. PMID 22322425 DOI: 10.1007/S00441-012-1341-8  0.581
2012 Cusimano M, Biziato D, Brambilla E, Donegà M, Alfaro-Cervello C, Snider S, Salani G, Pucci F, Comi G, Garcia-Verdugo JM, De Palma M, Martino G, Pluchino S. Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord. Brain : a Journal of Neurology. 135: 447-60. PMID 22271661 DOI: 10.1093/Brain/Awr339  0.519
2012 Herz J, Reitmeir R, Hagen SI, Reinboth BS, Guo Z, Zechariah A, ElAli A, Doeppner TR, Bacigaluppi M, Pluchino S, Kilic U, Kilic E, Hermann DM. Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions. Neurobiology of Disease. 45: 1077-85. PMID 22198574 DOI: 10.1016/J.Nbd.2011.12.026  0.312
2012 Pluchino S. Secreted Noncoding RNAs and Therapeutic Neural Stem Cell Plasticity Qscience Proceedings. 2012: 40. DOI: 10.5339/QPROC.2012.STEM.1.40  0.332
2012 Bolton S, Hassall D, Hildebrand D, Brück W, Huang JK, Pluchino S, McKevitt T, Parry J, McFarlane M, Fagg R, Roulois A. Anti-inflammatory Disease Therapies Toxicologic Pathology. 40: 122-125. DOI: 10.1177/0192623311425064  0.504
2011 Martino G, Pluchino S, Bonfanti L, Schwartz M. Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells. Physiological Reviews. 91: 1281-304. PMID 22013212 DOI: 10.1152/Physrev.00032.2010  0.55
2011 Pluchino S, Alfaro-Cervello C. Cyclooxygenase (COX)-1 takes control of adult hippocampal neurogenesis. Cell Cycle (Georgetown, Tex.). 10: 3229. PMID 21957491 DOI: 10.4161/Cc.10.19.17079  0.589
2011 L'episcopo F, Serapide MF, Tirolo C, Testa N, Caniglia S, Morale MC, Pluchino S, Marchetti B. A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection. Molecular Neurodegeneration. 6: 49. PMID 21752258 DOI: 10.1186/1750-1326-6-49  0.356
2011 Cimadamore F, Fishwick K, Giusto E, Gnedeva K, Cattarossi G, Miller A, Pluchino S, Brill LM, Bronner-Fraser M, Terskikh AV. Human ESC-derived neural crest model reveals a key role for SOX2 in sensory neurogenesis. Cell Stem Cell. 8: 538-51. PMID 21549328 DOI: 10.1016/J.Stem.2011.03.011  0.422
2011 Reitmeir R, Kilic E, Kilic U, Bacigaluppi M, ElAli A, Salani G, Pluchino S, Gassmann M, Hermann DM. Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity. Brain : a Journal of Neurology. 134: 84-99. PMID 21186263 DOI: 10.1093/Brain/Awq344  0.33
2011 L'Episcopo F, Tirolo C, Testa N, Caniglia S, Morale MC, Cossetti C, D'Adamo P, Zardini E, Andreoni L, Ihekwaba AE, Serra PA, Franciotta D, Martino G, Pluchino S, Marchetti B. Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. Neurobiology of Disease. 41: 508-27. PMID 21056667 DOI: 10.1016/J.Nbd.2010.10.023  0.415
2010 Melzi R, Antonioli B, Mercalli A, Battaglia M, Valle A, Pluchino S, Galli R, Sordi V, Bosi E, Martino G, Bonifacio E, Doglioni C, Piemonti L. Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice. Plos One. 5: e10357. PMID 20436918 DOI: 10.1371/Journal.Pone.0010357  0.458
2010 Pluchino S, Cusimano M, Bacigaluppi M, Martino G. Remodelling the Injured CNS through the Establishment of Atypical Ectopic Perivascular Neural Stem Cell Niches Archives Italiennes De Biologie. 148: 173-183. DOI: 10.4449/Aib.V148I2.1140  0.54
2010 Bacigaluppi M, Pluchino S, Jametti LP, Kilic E, Kilic U, Salani G, Brambilla E, West MJ, Comi G, Martino G, Hermann DM. Erratum: Delayed postischaemicneuroprotection following systemic neural stem cell transplantation involves multiple mechanisms (Brain (2009) 132:PART 8 (2239-2251) DOI: 10.1093/brain/awp174) Brain. 133. DOI: 10.1093/Brain/Awp226  0.483
2009 Gagliano N, Costa F, Cossetti C, Pettinari L, Bassi R, Chiriva-Internati M, Cobos E, Gioia M, Pluchino S. Glioma-astrocyte interaction modifies the astrocyte phenotype in a co-culture experimental model. Oncology Reports. 22: 1349-56. PMID 19885586 DOI: 10.3892/Or_00000574  0.34
2009 Pluchino S, Gritti A, Blezer E, Amadio S, Brambilla E, Borsellino G, Cossetti C, Del Carro U, Comi G, 't Hart B, Vescovi A, Martino G. Human neural stem cells ameliorate autoimmune encephalomyelitis in non-human primates. Annals of Neurology. 66: 343-54. PMID 19798728 DOI: 10.1002/Ana.21745  0.517
2009 Shechter R, London A, Varol C, Raposo C, Cusimano M, Yovel G, Rolls A, Mack M, Pluchino S, Martino G, Jung S, Schwartz M. Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice. Plos Medicine. 6: e1000113. PMID 19636355 DOI: 10.1371/Journal.Pmed.1000113  0.371
2009 Bacigaluppi M, Pluchino S, Peruzzotti-Jametti L, Jametti LP, Kilic E, Kilic U, Salani G, Brambilla E, West MJ, Comi G, Martino G, Hermann DM. Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms. Brain : a Journal of Neurology. 132: 2239-51. PMID 19617198 DOI: 10.1093/Brain/Awp174  0.481
2009 Pluchino S, Zanotti L, Brambilla E, Rovere-Querini P, Capobianco A, Alfaro-Cervello C, Salani G, Cossetti C, Borsellino G, Battistini L, Ponzoni M, Doglioni C, Garcia-Verdugo JM, Comi G, Manfredi AA, et al. Immune regulatory neural stem/precursor cells protect from central nervous system autoimmunity by restraining dendritic cell function. Plos One. 4: e5959. PMID 19543526 DOI: 10.1371/Journal.Pone.0005959  0.505
2009 Pluchino S, Zanotti L, Brini E, Ferrari S, Martino G. Regeneration and repair in multiple sclerosis: the role of cell transplantation. Neuroscience Letters. 456: 101-6. PMID 19429143 DOI: 10.1016/J.Neulet.2008.03.097  0.538
2008 Pluchino S, Muzio L, Imitola J, Deleidi M, Alfaro-Cervello C, Salani G, Porcheri C, Brambilla E, Cavasinni F, Bergamaschi A, Garcia-Verdugo JM, Comi G, Khoury SJ, Martino G. Persistent inflammation alters the function of the endogenous brain stem cell compartment. Brain : a Journal of Neurology. 131: 2564-78. PMID 18757884 DOI: 10.1093/Brain/Awn198  0.573
2008 Serra PA, Pluchino S, Marchetti B, Desole MS, Miele E. The MPTP mouse model: cues on DA release and neural stem cell restorative role. Parkinsonism & Related Disorders. 14: S189-93. PMID 18579428 DOI: 10.1016/J.Parkreldis.2008.04.029  0.333
2008 Pluchino S, Martino G. Neural stem cell-mediated immunomodulation: repairing the haemorrhagic brain. Brain : a Journal of Neurology. 131: 604-5. PMID 18292080 DOI: 10.1093/Brain/Awn015  0.557
2008 Butti E, Bergami A, Recchia A, Brambilla E, Del Carro U, Amadio S, Cattalini A, Esposito M, Stornaiuolo A, Comi G, Pluchino S, Mavilio F, Martino G, Furlan R. IL4 gene delivery to the CNS recruits regulatory T cells and induces clinical recovery in mouse models of multiple sclerosis. Gene Therapy. 15: 504-15. PMID 18239607 DOI: 10.1038/Gt.2008.10  0.325
2008 Pluchino S, Martino G. The therapeutic plasticity of neural stem/precursor cells in multiple sclerosis. Journal of the Neurological Sciences. 265: 105-10. PMID 17706971 DOI: 10.1016/J.Jns.2007.07.020  0.549
2008 Bacigaluppi M, Pluchino S, Martino G, Kilic E, Hermann DM. Neural stem/precursor cells for the treatment of ischemic stroke. Journal of the Neurological Sciences. 265: 73-7. PMID 17610905 DOI: 10.1016/J.Jns.2007.06.012  0.423
2007 Martino G, Pluchino S. Neural stem cells: guardians of the brain. Nature Cell Biology. 9: 1031-4. PMID 17762897 DOI: 10.1038/Ncb0907-1031  0.528
2007 Politi LS, Bacigaluppi M, Brambilla E, Cadioli M, Falini A, Comi G, Scotti G, Martino G, Pluchino S. Magnetic-resonance-based tracking and quantification of intravenously injected neural stem cell accumulation in the brains of mice with experimental multiple sclerosis. Stem Cells (Dayton, Ohio). 25: 2583-92. PMID 17600110 DOI: 10.1634/Stemcells.2007-0037  0.473
2007 Pluchino S, Zanotti L, Martino G. Rationale for the use of neural stem/precursor cells in immunemediated demyelinating disorders Journal of Neurology. 254: I23-I28. DOI: 10.1007/S00415-007-1005-X  0.587
2006 Ziv Y, Avidan H, Pluchino S, Martino G, Schwartz M. Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. Proceedings of the National Academy of Sciences of the United States of America. 103: 13174-9. PMID 16938843 DOI: 10.1073/Pnas.0603747103  0.525
2006 Martino G, Pluchino S. The therapeutic potential of neural stem cells. Nature Reviews. Neuroscience. 7: 395-406. PMID 16760919 DOI: 10.1038/Nrn1908  0.568
2006 Pluchino S, Bacigaluppi M, Bucello S, Butti E, Deleidi M, Zanotti L, Martino G, Furlan R. Gene and stem cell therapy for autoimmune demyelination. Ernst Schering Research Foundation Workshop. 133-46. PMID 16315612 DOI: 10.1007/3-540-27626-2_8  0.358
2006 Amadio S, Pluchino S, Brini E, Morana P, Guerriero R, Martinelli Boneschi F, Comi G, Zaratin P, Muzio V, del Carro U. Motor evoked potentials in a mouse model of chronic multiple sclerosis. Muscle & Nerve. 33: 265-73. PMID 16307439 DOI: 10.1002/Mus.20463  0.348
2006 Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Molecular and Cellular Neurosciences. 31: 149-60. PMID 16297637 DOI: 10.1016/J.Mcn.2005.10.006  0.428
2006 Politi L, Pluchino S, Bacigaluppi M, Brambilla E, Cadioli M, Cattalini A, Falini A, Anzalone N, Comi G, Martino G, Scotti G. In Vivo Magnetic Resonance Imaging of Intravenously Injected Neural Stem Cells in a Mouse Model of Multiple Sclerosis The Neuroradiology Journal. 19: 635-636. DOI: 10.1177/197140090601900514  0.404
2006 Ziv Y, Avidan H, Pluchino S, Martino G, Schwartz M. Erratum: Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury (Proceedings of the National Academy (2006) 103, (13174-13179) DOI: 10.1073/pnas.0603747103) Proceedings of the National Academy of Sciences of the United States of America. 103. DOI: 10.1073/Pnas.0608990103  0.44
2005 Pluchino S, Zanotti L, Rossi B, Brambilla E, Ottoboni L, Salani G, Martinello M, Cattalini A, Bergami A, Furlan R, Comi G, Constantin G, Martino G. Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism. Nature. 436: 266-71. PMID 16015332 DOI: 10.1038/Nature03889  0.562
2005 Pluchino S, Martino G. The therapeutic use of stem cells for myelin repair in autoimmune demyelinating disorders. Journal of the Neurological Sciences. 233: 117-9. PMID 15896808 DOI: 10.1016/J.Jns.2005.03.026  0.547
2005 Pluchino S, Zanotti L, Deleidi M, Martino G. Neural stem cells and their use as therapeutic tool in neurological disorders. Brain Research. Brain Research Reviews. 48: 211-9. PMID 15850660 DOI: 10.1016/J.Brainresrev.2004.12.011  0.574
2004 Pluchino S, Furlan R, Martino G. Cell-based remyelinating therapies in multiple sclerosis: evidence from experimental studies. Current Opinion in Neurology. 17: 247-55. PMID 15167057 DOI: 10.1097/00019052-200406000-00003  0.422
2003 Furlan R, Pluchino S, Martino G. Gene therapy-mediated modulation of immune processes in the central nervous system. Current Pharmaceutical Design. 9: 2002-8. PMID 12871186 DOI: 10.2174/1381612033454315  0.387
2003 Furlan R, Pluchino S, Martino G. The therapeutic use of gene therapy in inflammatory demyelinating diseases of the central nervous system. Current Opinion in Neurology. 16: 385-92. PMID 12858077 DOI: 10.1097/01.Wco.0000073941.19076.0A  0.412
2003 Pluchino S, Quattrini A, Brambilla E, Gritti A, Salani G, Dina G, Galli R, Del Carro U, Amadio S, Bergami A, Furlan R, Comi G, Vescovi AL, Martino G. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature. 422: 688-94. PMID 12700753 DOI: 10.1038/Nature01552  0.504
2003 Furlan R, Brambilla E, Sanvito F, Roccatagliata L, Olivieri S, Bergami A, Pluchino S, Uccelli A, Comi G, Martino G. Vaccination with amyloid-beta peptide induces autoimmune encephalomyelitis in C57/BL6 mice. Brain : a Journal of Neurology. 126: 285-91. PMID 12538398 DOI: 10.1093/Brain/Awg031  0.323
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