| Year |
Citation |
Score |
| 2024 |
Morris HR, Spillantini MG, Sue CM, Williams-Gray CH. The pathogenesis of Parkinson's disease. Lancet (London, England). 403: 293-304. PMID 38245249 DOI: 10.1016/S0140-6736(23)01478-2 |
0.31 |
|
| 2023 |
Goedert M, Crowther RA, Scheres SHW, Spillantini MG. Tau and neurodegeneration. Cytoskeleton (Hoboken, N.J.). PMID 38073060 DOI: 10.1002/cm.21812 |
0.438 |
|
| 2022 |
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lövestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, ... ... Spillantini MG, et al. Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature. PMID 35344985 DOI: 10.1038/s41586-022-04650-z |
0.349 |
|
| 2021 |
Brelstaff JH, Mason M, Katsinelos T, McEwan WA, Ghetti B, Tolkovsky AM, Spillantini MG. Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates. Science Advances. 7: eabg4980. PMID 34669475 DOI: 10.1126/sciadv.abg4980 |
0.3 |
|
| 2021 |
McMurray L, Macdonald JA, Ramakrishnan NK, Zhao Y, Williamson DW, Tietz O, Zhou X, Kealey S, Fagan SG, Smolek T, Cubinkova V, Žilka N, Spillantini MG, Tolkovsky AM, Goedert M, et al. Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models. Acs Chemical Neuroscience. PMID 33689290 DOI: 10.1021/acschemneuro.0c00790 |
0.35 |
|
| 2021 |
Goedert M, Spillantini MG, Falcon B, Zhang W, Newell KL, Hasegawa M, Scheres SHW, Ghetti B. Tau Protein and Frontotemporal Dementias. Advances in Experimental Medicine and Biology. 1281: 177-199. PMID 33433876 DOI: 10.1007/978-3-030-51140-1_12 |
0.441 |
|
| 2020 |
Migdalska-Richards A, Wegrzynowicz M, Harrison IF, Verona G, Bellotti V, Spillantini MG, Schapira AHV. L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils. Plos One. 15: e0238075. PMID 32833982 DOI: 10.1371/Journal.Pone.0238075 |
0.385 |
|
| 2020 |
Faustini G, Longhena F, Bruno A, Bono F, Grigoletto J, La Via L, Barbon A, Casiraghi A, Straniero V, Valoti E, Costantino G, Benfenati F, Missale C, Pizzi M, Spillantini MG, et al. Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate. Neurobiology of Disease. 138: 104789. PMID 32032728 DOI: 10.1016/J.Nbd.2020.104789 |
0.338 |
|
| 2020 |
Kaalund SS, Passamonti L, Allinson KSJ, Murley AG, Robbins TW, Spillantini MG, Rowe JB. Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity. Acta Neuropathologica Communications. 8: 11. PMID 32019605 DOI: 10.1186/S40478-020-0886-0 |
0.456 |
|
| 2019 |
Goedert M, Spillantini MG. Ordered Assembly of Tau Protein and Neurodegeneration. Advances in Experimental Medicine and Biology. 1184: 3-21. PMID 32096024 DOI: 10.1007/978-981-32-9358-8_1 |
0.471 |
|
| 2019 |
Schofield DJ, Irving L, Calo L, Bogstedt A, Rees G, Nuccitelli A, Narwal R, Petrone M, Roberts J, Brown L, Cusdin F, Dosanjh B, Lloyd C, Dobson C, Gurrell I, ... ... Spillantini MG, et al. Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo. Neurobiology of Disease. 104582. PMID 31445162 DOI: 10.1016/J.Nbd.2019.104582 |
0.35 |
|
| 2019 |
Wegrzynowicz M, Bar-On D, Calo' L, Anichtchik O, Iovino M, Xia J, Ryazanov S, Leonov A, Giese A, Dalley JW, Griesinger C, Ashery U, Spillantini MG. Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model. Acta Neuropathologica. PMID 31165254 DOI: 10.1007/S00401-019-02023-X |
0.387 |
|
| 2019 |
Forrest SL, Halliday GM, McCann H, McGeachie AB, McGinley CV, Hodges JR, Piguet O, Kwok JB, Spillantini MG, Kril JJ. Heritability in frontotemporal tauopathies. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 115-124. PMID 30723775 DOI: 10.1016/J.Dadm.2018.12.001 |
0.501 |
|
| 2019 |
Longhena F, Faustini G, Spillantini MG, Bellucci A. Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and Pathology. International Journal of Molecular Sciences. 20: 141. PMID 30609739 DOI: 10.3390/Ijms20010141 |
0.348 |
|
| 2018 |
Brelstaff J, Tolkovsky AM, Ghetti B, Goedert M, Spillantini MG. Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia. Cell Reports. 24: 1939-1948.e4. PMID 30134156 DOI: 10.1016/J.Celrep.2018.07.072 |
0.472 |
|
| 2017 |
Forrest SL, Kril JJ, Stevens CH, Kwok JB, Hallupp M, Kim WS, Huang Y, McGinley CV, Werka H, Kiernan MC, Götz J, Spillantini MG, Hodges JR, Ittner LM, Halliday GM. Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathies. Brain : a Journal of Neurology. PMID 29253099 DOI: 10.1093/Brain/Awx328 |
0.485 |
|
| 2017 |
Krogager TP, Ernst RJ, Elliott TS, Calo L, Beránek V, Ciabatti E, Spillantini MG, Tripodi M, Hastings MH, Chin JW. Labeling and identifying cell-specific proteomes in the mouse brain. Nature Biotechnology. PMID 29251727 DOI: 10.1038/Nbt.4056 |
0.302 |
|
| 2017 |
Sidoryk-Wegrzynowicz M, Gerber YN, Ries M, Sastre M, Tolkovsky AM, Spillantini MG. Astrocytes in mouse models of tauopathies acquire early deficits and lose neurosupportive functions. Acta Neuropathologica Communications. 5: 89. PMID 29187256 DOI: 10.1186/S40478-017-0478-9 |
0.408 |
|
| 2017 |
Sotiropoulos I, Galas MC, Silva JM, Skoulakis E, Wegmann S, Maina MB, Blum D, Sayas CL, Mandelkow EM, Mandelkow E, Spillantini MG, Sousa N, Avila J, Medina M, Mudher A, et al. Atypical, non-standard functions of the microtubule associated Tau protein. Acta Neuropathologica Communications. 5: 91. PMID 29187252 DOI: 10.1186/S40478-017-0489-6 |
0.473 |
|
| 2017 |
Spillantini MG, Goedert M. Neurodegeneration and the ordered assembly of α-synuclein. Cell and Tissue Research. PMID 29119326 DOI: 10.1007/S00441-017-2706-9 |
0.386 |
|
| 2017 |
Migdalska-Richards A, Wegrzynowicz M, Rusconi R, Deangeli G, Monte DAD, Spillantini MG, Schapira AHV. The L444P Gba1 mutation enhances alpha-synuclein induced loss of nigral dopaminergic neurons in mice Brain. 140: 2706-2721. PMID 28969384 DOI: 10.1093/Brain/Awx221 |
0.406 |
|
| 2017 |
Goedert M, Spillantini MG. Propagation of Tau aggregates. Molecular Brain. 10: 18. PMID 28558799 DOI: 10.1186/S13041-017-0298-7 |
0.454 |
|
| 2017 |
Goedert M, Jakes R, Spillantini MG. The Synucleinopathies: Twenty Years On. Journal of Parkinson's Disease. 7: S53-S71. PMID 28282814 DOI: 10.3233/Jpd-179005 |
0.379 |
|
| 2016 |
Bevan Jones WR, Cope TE, Passamonti L, Fryer TD, Hong YT, Aigbirhio F, Kril JJ, Forrest SL, Allinson K, Coles JP, Simon Jones P, Spillantini MG, Hodges JR, O'Brien JT, Rowe JB. [(18)F]AV-1451 PET in behavioral variant frontotemporal dementia due to MAPT mutation. Annals of Clinical and Translational Neurology. 3: 940-947. PMID 28097206 DOI: 10.1002/Acn3.366 |
0.422 |
|
| 2016 |
Tofaris GK, Goedert M, Spillantini MG. The Transcellular Propagation and Intracellular Trafficking of α-Synuclein. Cold Spring Harbor Perspectives in Medicine. PMID 27920026 DOI: 10.1101/Cshperspect.A024380 |
0.368 |
|
| 2016 |
Rittman T, Rubinov M, Vértes PE, Patel AX, Ginestet CE, Ghosh BC, Barker RA, Spillantini MG, Bullmore ET, Rowe JB. Regional expression of the MAPT gene is associated with loss of hubs in brain networks and cognitive impairment in Parkinson disease and progressive supranuclear palsy. Neurobiology of Aging. 48: 153-160. PMID 27697694 DOI: 10.1016/J.Neurobiolaging.2016.09.001 |
0.386 |
|
| 2016 |
Yang S, Kuan WL, Spillantini MG. Progressive tauopathy in P301S tau transgenic mice is associated with a functional deficit of the olfactory system. The European Journal of Neuroscience. PMID 27422327 DOI: 10.1111/Ejn.13333 |
0.39 |
|
| 2016 |
Mazzaro N, Barini E, Spillantini MG, Goedert M, Medini P, Gasparini L. Tau-Driven Neuronal and Neurotrophic Dysfunction in a Mouse Model of Early Tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 2086-100. PMID 26888921 DOI: 10.1523/Jneurosci.0774-15.2016 |
0.425 |
|
| 2016 |
Calo L, Wegrzynowicz M, Santivañez-Perez J, Spillantini MG. Synaptic failure and α-synuclein Movement Disorders. 31: 169-177. PMID 26790375 DOI: 10.1002/Mds.26479 |
0.338 |
|
| 2016 |
Tozzi A, de Iure A, Bagetta V, Tantucci M, Durante V, Quiroga-Varela A, Costa C, Di Filippo M, Ghiglieri V, Latagliata EC, Wegrzynowicz M, Decressac M, Giampà C, Dalley JW, Xia J, ... ... Spillantini MG, et al. Alpha-Synuclein Produces Early Behavioral Alterations via Striatal Cholinergic Synaptic Dysfunction by Interacting With GluN2D N-Methyl-D-Aspartate Receptor Subunit. Biological Psychiatry. 79: 402-14. PMID 26392130 DOI: 10.1016/J.Biopsych.2015.08.013 |
0.35 |
|
| 2016 |
Bellucci A, Zaltieri M, Longhena F, Faustini G, Grigoletto J, Favero G, Castrezzati S, Rezzani R, Pizzi M, Benfenati F, Spillantini MG, Missale C, Spano P. Synapsin III alterations in Parkinson's disease Parkinsonism & Related Disorders. 22: e189. DOI: 10.1016/J.Parkreldis.2015.10.485 |
0.383 |
|
| 2016 |
Brelstaff JH, Tolkovsky A, Spillantini MG. P1-160: Phosphatidylserine Exposure on Cultured Dorsal Root Ganglia Neurons From P301S TAU Mice Suggest Phagoptosis as an Extrinsic Route of Cell Death in Tauopathy Alzheimer's & Dementia. 12: P464-P464. DOI: 10.1016/J.Jalz.2016.06.907 |
0.334 |
|
| 2015 |
Brelstaff J, Spillantini MG, Tolkovsky AM. pFTAA: a high affinity oligothiophene probe that detects filamentous tau in vivo and in cultured neurons. Neural Regeneration Research. 10: 1746-7. PMID 26807101 DOI: 10.4103/1673-5374.165298 |
0.54 |
|
| 2015 |
Ossola B, Zhao C, Compston A, Pluchino S, Franklin RJ, Spillantini MG. Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation. Glia. PMID 26576485 DOI: 10.1002/Glia.22940 |
0.334 |
|
| 2015 |
Goedert M, Spillantini MG, Crowther RA. A Brief History of Tau. Clinical Chemistry. 61: 1417-8. PMID 26330509 DOI: 10.1373/Clinchem.2015.245142 |
0.482 |
|
| 2015 |
McCarthy A, Lonergan R, Olszewska DA, O'Dowd S, Cummins G, Magennis B, Fallon EM, Pender N, Huey ED, Cosentino S, O'Rourke K, Kelly BD, O'Connell M, Delon I, Farrell M, ... Spillantini MG, et al. Closing the tau loop: the missing tau mutation. Brain : a Journal of Neurology. PMID 26297556 DOI: 10.1093/Brain/Awv234 |
0.458 |
|
| 2015 |
Iovino M, Agathou S, González-Rueda A, Del Castillo Velasco-Herrera M, Borroni B, Alberici A, Lynch T, O'Dowd S, Geti I, Gaffney D, Vallier L, Paulsen O, Káradóttir RT, Spillantini MG. Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations. Brain : a Journal of Neurology. PMID 26220942 DOI: 10.1093/Brain/Awv222 |
0.448 |
|
| 2015 |
Brelstaff J, Ossola B, Neher JJ, Klingstedt T, Nilsson KP, Goedert M, Spillantini MG, Tolkovsky AM. The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice. Frontiers in Neuroscience. 9: 184. PMID 26074756 DOI: 10.3389/Fnins.2015.00184 |
0.472 |
|
| 2015 |
Zaltieri M, Grigoletto J, Longhena F, Navarria L, Favero G, Castrezzati S, Colivicchi MA, Della Corte L, Rezzani R, Pizzi M, Benfenati F, Spillantini MG, Missale C, Spano P, Bellucci A. α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons. Journal of Cell Science. 128: 2231-43. PMID 25967550 DOI: 10.1242/Jcs.157867 |
0.34 |
|
| 2015 |
Vuono R, Winder-Rhodes S, de Silva R, Cisbani G, Drouin-Ouellet J, Spillantini MG, Cicchetti F, Barker RA. The role of tau in the pathological process and clinical expression of Huntington's disease. Brain : a Journal of Neurology. 138: 1907-18. PMID 25953777 DOI: 10.1093/Brain/Awv107 |
0.497 |
|
| 2015 |
Wood R, Moodley K, Hodges JR, Allinson K, Spillantini MG, Chan D. Slowly progressive behavioural presentation in two UK cases with the R406W MAPT mutation. Neuropathology and Applied Neurobiology. PMID 25942996 DOI: 10.1111/Nan.12247 |
0.426 |
|
| 2015 |
Navarria L, Zaltieri M, Longhena F, Spillantini MG, Missale C, Spano P, Bellucci A. Alpha-synuclein modulates NR2B-containing NMDA receptors and decreases their levels after rotenone exposure. Neurochemistry International. 85: 14-23. PMID 25846226 DOI: 10.1016/J.Neuint.2015.03.008 |
0.367 |
|
| 2015 |
Hunn BH, Cragg SJ, Bolam JP, Spillantini MG, Wade-Martins R. Impaired intracellular trafficking defines early Parkinson's disease. Trends in Neurosciences. 38: 178-88. PMID 25639775 DOI: 10.1016/J.Tins.2014.12.009 |
0.388 |
|
| 2015 |
Duyckaerts C, Braak H, Brion JP, Buée L, Del Tredici K, Goedert M, Halliday G, Neumann M, Spillantini MG, Tolnay M, Uchihara T. PART is part of Alzheimer disease. Acta Neuropathologica. 129: 749-56. PMID 25628035 DOI: 10.1007/S00401-015-1390-7 |
0.43 |
|
| 2015 |
Yang S, Cacquevel M, Saksida LM, Bussey TJ, Schneider BL, Aebischer P, Melani R, Pizzorusso T, Fawcett JW, Spillantini MG. Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology. Experimental Neurology. 265: 48-58. PMID 25483398 DOI: 10.1016/J.Expneurol.2014.11.013 |
0.358 |
|
| 2015 |
Hall K, Yang S, Sauchanka O, Spillantini MG, Anichtchik O. Behavioural deficits in transgenic mice expressing human truncated (1-120 amino acid) alpha-synuclein. Experimental Neurology. 264: 8-13. PMID 25450466 DOI: 10.1016/J.Expneurol.2014.11.003 |
0.373 |
|
| 2014 |
Herva ME, Spillantini MG. Parkinson's disease as a member of Prion-like disorders. Virus Research. PMID 25456401 DOI: 10.1016/J.Virusres.2014.10.016 |
0.434 |
|
| 2014 |
Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, ... ... Spillantini MG, et al. Frontotemporal dementia and its subtypes: a genome-wide association study. The Lancet. Neurology. 13: 686-99. PMID 24943344 DOI: 10.1016/S1474-4422(14)70065-1 |
0.343 |
|
| 2014 |
Malek N, Swallow D, Grosset KA, Anichtchik O, Spillantini M, Grosset DG. Alpha-synuclein in peripheral tissues and body fluids as a biomarker for Parkinson's disease - a systematic review. Acta Neurologica Scandinavica. 130: 59-72. PMID 24702516 DOI: 10.1111/Ane.12247 |
0.326 |
|
| 2014 |
Herva ME, Zibaee S, Fraser G, Barker RA, Goedert M, Spillantini MG. Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA). The Journal of Biological Chemistry. 289: 11897-905. PMID 24584936 DOI: 10.1074/Jbc.M113.542340 |
0.35 |
|
| 2014 |
Iovino M, Pfisterer U, Holton JL, Lashley T, Swingler RJ, Calo L, Treacy R, Revesz T, Parmar M, Goedert M, Muqit MM, Spillantini MG. The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons. Acta Neuropathologica. 127: 283-95. PMID 24292008 DOI: 10.1007/S00401-013-1219-1 |
0.481 |
|
| 2013 |
Mellone M, Kestoras D, Andrews MR, Dassie E, Crowther RA, Stokin GB, Tinsley J, Horne G, Goedert M, Tolkovsky AM, Spillantini MG. Tau pathology is present in vivo and develops in vitro in sensory neurons from human P301S tau transgenic mice: a system for screening drugs against tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18175-89. PMID 24227726 DOI: 10.1523/Jneurosci.4933-12.2013 |
0.478 |
|
| 2013 |
Anichtchik O, Calo L, Spillantini MG. Synaptic dysfunction in synucleinopathies. Cns & Neurological Disorders Drug Targets. 12: 1094-100. PMID 24040824 DOI: 10.2174/18715273113129990114 |
0.35 |
|
| 2013 |
Garcia-Reitboeck P, Anichtchik O, Dalley JW, Ninkina N, Tofaris GK, Buchman VL, Spillantini MG. Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra. Experimental Neurology. 248: 541-5. PMID 23933574 DOI: 10.1016/J.Expneurol.2013.07.015 |
0.362 |
|
| 2013 |
Spillantini MG, Goedert M. Tau pathology and neurodegeneration. The Lancet. Neurology. 12: 609-22. PMID 23684085 DOI: 10.1016/S1474-4422(13)70090-5 |
0.534 |
|
| 2013 |
Dassie E, Andrews MR, Bensadoun JC, Cacquevel M, Schneider BL, Aebischer P, Wouters FS, Richardson JC, Hussain I, Howlett DR, Spillantini MG, Fawcett JW. Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model. Neurobiology of Aging. 34: 1355-68. PMID 23273572 DOI: 10.1016/J.Neurobiolaging.2012.11.011 |
0.506 |
|
| 2013 |
Goedert M, Spillantini MG, Del Tredici K, Braak H. 100 years of Lewy pathology. Nature Reviews. Neurology. 9: 13-24. PMID 23183883 DOI: 10.1038/Nrneurol.2012.242 |
0.386 |
|
| 2013 |
King A, Al-Sarraj S, Troakes C, Smith BN, Maekawa S, Iovino M, Spillantini MG, Shaw CE. Mixed tau, TDP-43 and p62 pathology in FTLD associated with a C9ORF72 repeat expansion and p.Ala239Thr MAPT (tau) variant. Acta Neuropathologica. 125: 303-10. PMID 23053136 DOI: 10.1007/S00401-012-1050-0 |
0.487 |
|
| 2013 |
Bezard E, Yue Z, Kirik D, Spillantini MG. Animal models of Parkinson's disease: limits and relevance to neuroprotection studies. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 61-70. PMID 22753348 DOI: 10.1002/Mds.25108 |
0.339 |
|
| 2013 |
Mazzaro N, Barini E, Goedert M, Spillantini M, Medini P, Gasparini L. Tauopathy-induced retinal dysfunction in the P301S mutant human tau transgenic mouse Molecular Neurodegeneration. 8: P57. DOI: 10.1186/1750-1326-8-S1-P57 |
0.431 |
|
| 2013 |
Barini E, Mazzaro N, Spillantini MG, Goedert M, Medini P, Gasparini L. Alterations of neurotrophin signaling in the retina of the P301S mutant human tau transgenic mouse Alzheimers & Dementia. 9: 169. DOI: 10.1016/J.Jalz.2013.05.266 |
0.423 |
|
| 2013 |
Mazzaro N, Barini E, Spillantini MG, Goedert M, Medini P, Gasparini L. Neurotrophin signaling is altered in the retina of the P301S mutant human tau transgenic mouse Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.265 |
0.354 |
|
| 2012 |
Baiguera C, Alghisi M, Pinna A, Bellucci A, De Luca MA, Frau L, Morelli M, Ingrassia R, Benarese M, Porrini V, Pellitteri M, Bertini G, Fabene PF, Sigala S, Spillantini MG, et al. Late-onset Parkinsonism in NFκB/c-Rel-deficient mice. Brain : a Journal of Neurology. 135: 2750-65. PMID 22915735 DOI: 10.1093/Brain/Aws193 |
0.325 |
|
| 2012 |
Costa C, Sgobio C, Siliquini S, Tozzi A, Tantucci M, Ghiglieri V, Di Filippo M, Pendolino V, de Iure A, Marti M, Morari M, Spillantini MG, Latagliata EC, Pascucci T, Puglisi-Allegra S, et al. Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson's disease. Brain : a Journal of Neurology. 135: 1884-99. PMID 22561640 DOI: 10.1093/Brain/Aws101 |
0.307 |
|
| 2012 |
Bull ND, Guidi A, Goedert M, Martin KR, Spillantini MG. Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau. Plos One. 7: e34724. PMID 22496848 DOI: 10.1371/Journal.Pone.0034724 |
0.346 |
|
| 2012 |
Goedert M, Ghetti B, Spillantini MG. Frontotemporal dementia: implications for understanding Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 2: a006254. PMID 22355793 DOI: 10.1101/Cshperspect.A006254 |
0.457 |
|
| 2012 |
Jung HH, Bremer J, Streffer J, Virdee K, Spillantini MG, Crowther RA, Brugger P, Van Broeckhoven C, Aguzzi A, Tolnay M. Phenotypic variation of autosomal-dominant corticobasal degeneration. European Neurology. 67: 142-50. PMID 22261560 DOI: 10.1159/000334731 |
0.432 |
|
| 2012 |
Winder-Rhodes SE, Garcia-Reitböck P, Ban M, Evans JR, Jacques TS, Kemppinen A, Foltynie T, Williams-Gray CH, Chinnery PF, Hudson G, Burn DJ, Allcock LM, Sawcer SJ, Barker RA, Spillantini MG. Genetic and pathological links between Parkinson's disease and the lysosomal disorder Sanfilippo syndrome. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 312-5. PMID 22102531 DOI: 10.1002/Mds.24029 |
0.358 |
|
| 2012 |
Spillantini M. Parkinson's disease-mild cognitive impairment (PD-MCI) and Parkinson's disease Dementia (PDD) Alzheimers & Dementia. 8: 725. DOI: 10.1016/J.Jalz.2012.05.1950 |
0.36 |
|
| 2012 |
Goedert M, Spillantini MG. Synucleinopathies and Tauopathies Basic Neurochemistry. 829-843. DOI: 10.1016/B978-0-12-374947-5.00047-X |
0.374 |
|
| 2011 |
Love S, Spillantini MG. Unpicking frontotemporal lobar degeneration. Brain : a Journal of Neurology. 134: 2453-5. PMID 21859768 DOI: 10.1093/Brain/Awr176 |
0.415 |
|
| 2011 |
Goedert M, Spillantini MG. Pathogenesis of the tauopathies. Journal of Molecular Neuroscience : Mn. 45: 425-31. PMID 21785996 DOI: 10.1007/S12031-011-9593-4 |
0.536 |
|
| 2011 |
Spillantini MG, Iovino M, Vuono R. Release of growth factors by neuronal precursor cells as a treatment for diseases with tau pathology. Archives Italiennes De Biologie. 149: 215-23. PMID 21701993 DOI: 10.4449/Aib.V149I1.1360 |
0.405 |
|
| 2011 |
Shelkovnikova TA, Ustyugov AA, Millership S, Peters O, Anichtchik O, Spillantini MG, Buchman VL, Bachurin SO, Ninkina NN. Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice. Neuro-Degenerative Diseases. 8: 430-7. PMID 21576917 DOI: 10.1159/000324989 |
0.418 |
|
| 2011 |
Anfossi M, Vuono R, Maletta R, Virdee K, Mirabelli M, Colao R, Puccio G, Bernardi L, Frangipane F, Gallo M, Geracitano S, Tomaino C, Curcio SA, Zannino G, Lamenza F, ... ... Spillantini MG, et al. Compound heterozygosity of 2 novel MAPT mutations in frontotemporal dementia. Neurobiology of Aging. 32: 757.e1-757.e11. PMID 21295377 DOI: 10.1016/J.Neurobiolaging.2010.12.013 |
0.417 |
|
| 2011 |
Bellucci A, Bugiani O, Ghetti B, Spillantini MG. Presence of reactive microglia and neuroinflammatory mediators in a case of frontotemporal dementia with P301S mutation. Neuro-Degenerative Diseases. 8: 221-9. PMID 21212632 DOI: 10.1159/000322228 |
0.448 |
|
| 2011 |
Xiong L, Xuereb JH, Spillantini MG, Patterson K, Hodges JR, Nestor PJ. Clinical comparison of progressive aphasia associated with Alzheimer versus FTD-spectrum pathology. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 254-60. PMID 20841368 DOI: 10.1136/Jnnp.2010.209916 |
0.358 |
|
| 2011 |
Gasparini L, Crowther RA, Martin KR, Berg N, Coleman M, Goedert M, Spillantini MG. Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability. Neurobiology of Aging. 32: 419-33. PMID 19356824 DOI: 10.1016/J.Neurobiolaging.2009.03.002 |
0.415 |
|
| 2011 |
Iovino M, Patani R, Chandran S, Spillantini MG. P3-126: Human stem cell-derived neurones as a model to study tau function and dysfunction Alzheimer's & Dementia. 7: S555-S555. DOI: 10.1016/J.Jalz.2011.05.1567 |
0.341 |
|
| 2011 |
Yang S, Goedert M, Spillantini MG. Progressive tauopathy in P301S tau transgenic mice is associated with a functional deficit of the olfactory system Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1490 |
0.347 |
|
| 2010 |
Iovino M, Patani R, Watts C, Chandran S, Spillantini MG. Human stem cell-derived neurons: a system to study human tau function and dysfunction. Plos One. 5: e13947. PMID 21085657 DOI: 10.1371/Journal.Pone.0013947 |
0.461 |
|
| 2010 |
Hampton DW, Webber DJ, Bilican B, Goedert M, Spillantini MG, Chandran S. Cell-mediated neuroprotection in a mouse model of human tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9973-83. PMID 20668182 DOI: 10.1523/Jneurosci.0834-10.2010 |
0.535 |
|
| 2010 |
Garcia-Reitböck P, Anichtchik O, Bellucci A, Iovino M, Ballini C, Fineberg E, Ghetti B, Della Corte L, Spano P, Tofaris GK, Goedert M, Spillantini MG. SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. Brain : a Journal of Neurology. 133: 2032-44. PMID 20534649 DOI: 10.1093/Brain/Awq132 |
0.413 |
|
| 2010 |
Anderson JM, Patani R, Reynolds R, Nicholas R, Compston A, Spillantini MG, Chandran S. Abnormal tau phosphorylation in primary progressive multiple sclerosis. Acta Neuropathologica. 119: 591-600. PMID 20306268 DOI: 10.1007/S00401-010-0671-4 |
0.423 |
|
| 2010 |
Bruni AC, Bernardi L, Colao R, Rubino E, Smirne N, Frangipane F, Terni B, Curcio SA, Mirabelli M, Clodomiro A, Di Lorenzo R, Maletta R, Anfossi M, Gallo M, Geracitano S, ... ... Spillantini MG, et al. Worldwide distribution of PSEN1 Met146Leu mutation: a large variability for a founder mutation. Neurology. 74: 798-806. PMID 20164095 DOI: 10.1212/Wnl.0B013E3181D52785 |
0.354 |
|
| 2010 |
Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Spillantini MG, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536 |
0.306 |
|
| 2010 |
Pan-Montojo F, Anichtchik O, Dening Y, Knels L, Pursche S, Jung R, Jackson S, Gille G, Spillantini MG, Reichmann H, Funk RH. Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice. Plos One. 5: e8762. PMID 20098733 DOI: 10.1038/Npre.2009.3352.2 |
0.323 |
|
| 2010 |
Rosi MC, Luccarini I, Grossi C, Fiorentini A, Spillantini MG, Prisco A, Scali C, Gianfriddo M, Caricasole A, Terstappen GC, Casamenti F. Increased Dickkopf-1 expression in transgenic mouse models of neurodegenerative disease. Journal of Neurochemistry. 112: 1539-51. PMID 20050968 DOI: 10.1111/J.1471-4159.2009.06566.X |
0.47 |
|
| 2010 |
Scattoni ML, Gasparini L, Alleva E, Goedert M, Calamandrei G, Spillantini MG. Early behavioural markers of disease in P301S tau transgenic mice. Behavioural Brain Research. 208: 250-7. PMID 20004218 DOI: 10.1016/J.Bbr.2009.12.002 |
0.384 |
|
| 2010 |
Hodges JR, Mitchell J, Dawson K, Spillantini MG, Xuereb JH, McMonagle P, Nestor PJ, Patterson K. Semantic dementia: demography, familial factors and survival in a consecutive series of 100 cases. Brain : a Journal of Neurology. 133: 300-6. PMID 19805492 DOI: 10.1093/Brain/Awp248 |
0.385 |
|
| 2010 |
Hampton DW, Webber DJ, Bilican B, Goedert M, Spillantini MG, Chandran S. O4-03-08: Cell-mediated Neuroprotection in P301S Human Tau Transgenic Mice, a Model of Human Tauopathy Alzheimer's & Dementia. 6: e17-e18. DOI: 10.1016/J.Jalz.2010.08.053 |
0.331 |
|
| 2009 |
Pereira JM, Williams GB, Acosta-Cabronero J, Pengas G, Spillantini MG, Xuereb JH, Hodges JR, Nestor PJ. Atrophy patterns in histologic vs clinical groupings of frontotemporal lobar degeneration. Neurology. 72: 1653-60. PMID 19433738 DOI: 10.1212/Wnl.0B013E3181A55Fa2 |
0.368 |
|
| 2009 |
Anderson JM, Patani R, Reynolds R, Nicholas R, Compston A, Spillantini MG, Chandran S. Evidence for abnormal tau phosphorylation in early aggressive multiple sclerosis. Acta Neuropathologica. 117: 583-9. PMID 19288121 DOI: 10.1007/S00401-009-0515-2 |
0.462 |
|
| 2009 |
Borroni B, Gardoni F, Parnetti L, Magno L, Malinverno M, Saggese E, Calabresi P, Spillantini MG, Padovani A, Di Luca M. Pattern of Tau forms in CSF is altered in progressive supranuclear palsy. Neurobiology of Aging. 30: 34-40. PMID 17709155 DOI: 10.1016/J.Neurobiolaging.2007.05.009 |
0.483 |
|
| 2008 |
Anderson JM, Hampton DW, Patani R, Pryce G, Crowther RA, Reynolds R, Franklin RJ, Giovannoni G, Compston DA, Baker D, Spillantini MG, Chandran S. Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis. Brain : a Journal of Neurology. 131: 1736-48. PMID 18567922 DOI: 10.1093/Brain/Awn119 |
0.453 |
|
| 2008 |
Ye L, Velasco A, Fraser G, Beach TG, Sue L, Osredkar T, Libri V, Spillantini MG, Goedert M, Lockhart A. In vitro high affinity alpha-synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain. Journal of Neurochemistry. 105: 1428-37. PMID 18221373 DOI: 10.1111/J.1471-4159.2008.05245.X |
0.372 |
|
| 2008 |
Delobel P, Lavenir I, Fraser G, Ingram E, Holzer M, Ghetti B, Spillantini MG, Crowther RA, Goedert M. Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy. The American Journal of Pathology. 172: 123-31. PMID 18079436 DOI: 10.2353/Ajpath.2008.070627 |
0.484 |
|
| 2008 |
Spina S, Farlow MR, Unverzagt FW, Kareken DA, Murrell JR, Fraser G, Epperson F, Crowther RA, Spillantini MG, Goedert M, Ghetti B. The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family. Brain : a Journal of Neurology. 131: 72-89. PMID 18065436 DOI: 10.1093/Brain/Awm280 |
0.471 |
|
| 2008 |
Spillantini MG. S2-03-01: Tau-associated neurodegeneration in Alzheimer's Disease and tauopathy Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.283 |
0.449 |
|
| 2007 |
Magnani E, Fan J, Gasparini L, Golding M, Williams M, Schiavo G, Goedert M, Amos LA, Spillantini MG. Interaction of tau protein with the dynactin complex. The Embo Journal. 26: 4546-54. PMID 17932487 DOI: 10.1038/Sj.Emboj.7601878 |
0.488 |
|
| 2007 |
Michell AW, Tofaris GK, Gossage H, Tyers P, Spillantini MG, Barker RA. The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease. Cell Transplantation. 16: 461-74. PMID 17708336 DOI: 10.3727/000000007783464911 |
0.39 |
|
| 2007 |
Goris A, Williams-Gray CH, Clark GR, Foltynie T, Lewis SJ, Brown J, Ban M, Spillantini MG, Compston A, Burn DJ, Chinnery PF, Barker RA, Sawcer SJ. Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease. Annals of Neurology. 62: 145-53. PMID 17683088 DOI: 10.1002/Ana.21192 |
0.414 |
|
| 2007 |
Gasparini L, Terni B, Spillantini MG. Frontotemporal dementia with tau pathology. Neuro-Degenerative Diseases. 4: 236-53. PMID 17596718 DOI: 10.1159/000101848 |
0.549 |
|
| 2007 |
Lambourne SL, Humby T, Isles AR, Emson PC, Spillantini MG, Wilkinson LS. Impairments in impulse control in mice transgenic for the human FTDP-17 tauV337M mutation are exacerbated by age. Human Molecular Genetics. 16: 1708-19. PMID 17517691 DOI: 10.1093/Hmg/Ddm119 |
0.483 |
|
| 2007 |
van Swieten J, Spillantini MG. Hereditary frontotemporal dementia caused by Tau gene mutations. Brain Pathology (Zurich, Switzerland). 17: 63-73. PMID 17493040 DOI: 10.1111/J.1750-3639.2007.00052.X |
0.534 |
|
| 2007 |
Goedert M, Spillantini MG. Chapter 4 Tau Protein and the Dementias Blue Books of Neurology. 30: 88-111. DOI: 10.1016/S1877-184X(09)70055-3 |
0.33 |
|
| 2006 |
Goedert M, Spillantini MG. A century of Alzheimer's disease. Science (New York, N.Y.). 314: 777-81. PMID 17082447 DOI: 10.1126/Science.1132814 |
0.488 |
|
| 2006 |
Goedert M, Spillantini MG. Frontotemporal lobar degeneration through loss of progranulin function. Brain : a Journal of Neurology. 129: 2808-10. PMID 17071919 DOI: 10.1093/Brain/Awl291 |
0.428 |
|
| 2006 |
Spillantini MG, Murrell JR, Goedert M, Farlow M, Klug A, Ghetti B. Mutations in the tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia (MSTD). Journal of Alzheimer's Disease : Jad. 9: 373-80. PMID 16914875 DOI: 10.3233/Jad-2006-9S342 |
0.502 |
|
| 2006 |
Tofaris GK, Garcia Reitböck P, Humby T, Lambourne SL, O'Connell M, Ghetti B, Gossage H, Emson PC, Wilkinson LS, Goedert M, Spillantini MG. Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3942-50. PMID 16611810 DOI: 10.1523/Jneurosci.4965-05.2006 |
0.381 |
|
| 2006 |
Brelstaff JH, Tolkovsky A, Ghetti BF, Goedert M, Spillantini MG. P4-257: NEURONS WITH TAU AGGREGATES EXPOSE PHOSPHATIDYLSERINE AND ARE PHAGOCYTOSED LIVE BY MICROGLIA Alzheimer's & Dementia. 14: P1545-P1545. DOI: 10.1016/J.Jalz.2018.07.079 |
0.391 |
|
| 2006 |
Gasparini L, Goedert M, Spillantini MG. P1-086: Hyperphosphorylated tau accumulates in retinal ganglion neurons of P301S tau transgenic mice Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.461 |
0.395 |
|
| 2006 |
Ignjatovic T, Yancopolou D, Ince PG, Lowe J, Layfield R, Shaw PJ, Hodges JR, Spillantini MG. P4-119: Characterization of ubiquitin positive inclusions in frontotemporal dementia Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1858 |
0.347 |
|
| 2006 |
Bruni AC, Terni B, Bernardi L, Tomaino C, Maletta R, Smirne N, Calignano C, Paonessa A, Leotta A, Santo L, Puccio G, Colao R, Frangipane F, Curcio SAM, Mirabelli M, ... ... Spillantini MG, et al. P3-193: Genotype-phenotype relationship is lacking in families with PS1-Met146Leu founder mutation Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1461 |
0.3 |
|
| 2005 |
Borroni B, Yancopoulou D, Tsutsui M, Padovani A, Sawcer SJ, Hodges JR, Spillantini MG. Association between tau H2 haplotype and age at onset in frontotemporal dementia. Archives of Neurology. 62: 1419-22. PMID 16157749 DOI: 10.1001/Archneur.62.9.1419 |
0.456 |
|
| 2005 |
Tofaris GK, Spillantini MG. Alpha-synuclein dysfunction in Lewy body diseases. Movement Disorders : Official Journal of the Movement Disorder Society. 20: S37-44. PMID 16092089 DOI: 10.1002/Mds.20538 |
0.429 |
|
| 2005 |
Skibinski G, Parkinson NJ, Brown JM, Chakrabarti L, Lloyd SL, Hummerich H, Nielsen JE, Hodges JR, Spillantini MG, Thusgaard T, Brandner S, Brun A, Rossor MN, Gade A, Johannsen P, et al. Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. Nature Genetics. 37: 806-8. PMID 16041373 DOI: 10.1038/Ng1609 |
0.388 |
|
| 2005 |
Yancopoulou D, Xuereb JH, Crowther RA, Hodges JR, Spillantini MG. Tau and alpha-synuclein inclusions in a case of familial frontotemporal dementia and progressive aphasia. Journal of Neuropathology and Experimental Neurology. 64: 245-53. PMID 15804056 DOI: 10.1093/Jnen/64.3.245 |
0.506 |
|
| 2004 |
Bruni AC, Kawarai T, Spillantini MG, St-George Hyslop PH, Leotta A, Lio S, Foncin JF, El Hachimi KH. [Familial fronto-temporal dementia with brain stem ubiquitin-positive neuronal inclusions]. Revue Neurologique. 160: 1171-9. PMID 15602363 DOI: 10.1016/S0035-3787(04)71162-5 |
0.466 |
|
| 2004 |
Piguet O, Brooks WS, Halliday GM, Schofield PR, Stanford PM, Kwok JB, Spillantini MG, Yancopoulou D, Nestor PJ, Broe GA, Hodges JR. Similar early clinical presentations in familial and non-familial frontotemporal dementia. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 1743-5. PMID 15548495 DOI: 10.1136/Jnnp.2003.031948 |
0.459 |
|
| 2004 |
Bellucci A, Westwood AJ, Ingram E, Casamenti F, Goedert M, Spillantini MG. Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein. The American Journal of Pathology. 165: 1643-52. PMID 15509534 DOI: 10.1016/S0002-9440(10)63421-9 |
0.381 |
|
| 2004 |
Takao M, Ghetti B, Yoshida H, Piccardo P, Narain Y, Murrell JR, Vidal R, Glazier BS, Jakes R, Tsutsui M, Spillantini MG, Crowther RA, Goedert M, Koto A. Early-onset dementia with Lewy bodies. Brain Pathology (Zurich, Switzerland). 14: 137-47. PMID 15193026 DOI: 10.1111/J.1750-3639.2004.Tb00046.X |
0.434 |
|
| 2004 |
Brown J, Gydesen S, Johannsen P, Gade A, Skibinski G, Chakrabarti L, Brun A, Spillantini M, Yancopoulou D, Thusgaard T, Sorensen A, Fisher E, Collinge J. Frontotemporal dementia linked to chromosome 3. Dementia and Geriatric Cognitive Disorders. 17: 274-6. PMID 15178935 DOI: 10.1159/000077153 |
0.382 |
|
| 2003 |
Yancopoulou D, Spillantini MG. Tau protein in familial and sporadic diseases. Neuromolecular Medicine. 4: 37-48. PMID 14528051 DOI: 10.1385/Nmm:4:1-2:37 |
0.55 |
|
| 2003 |
Yancopoulou D, Crowther RA, Chakrabarti L, Gydesen S, Brown JM, Spillantini MG. Tau protein in frontotemporal dementia linked to chromosome 3 (FTD-3). Journal of Neuropathology and Experimental Neurology. 62: 878-82. PMID 14503643 DOI: 10.1093/Jnen/62.8.878 |
0.468 |
|
| 2003 |
Tofaris GK, Razzaq A, Ghetti B, Lilley KS, Spillantini MG. Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function. The Journal of Biological Chemistry. 278: 44405-11. PMID 12923179 DOI: 10.1074/Jbc.M308041200 |
0.409 |
|
| 2003 |
Powers JM, Byrne NP, Ito M, Takao M, Yankopoulou D, Spillantini MG, Ghetti B. A novel leukoencephalopathy associated with tau deposits primarily in white matter glia. Acta Neuropathologica. 106: 181-7. PMID 12783250 DOI: 10.1007/S00401-003-0719-9 |
0.387 |
|
| 2002 |
Ingram EM, Spillantini MG. Tau gene mutations: dissecting the pathogenesis of FTDP-17. Trends in Molecular Medicine. 8: 555-62. PMID 12470988 DOI: 10.1016/S1471-4914(02)02440-1 |
0.537 |
|
| 2002 |
Gydesen S, Brown JM, Brun A, Chakrabarti L, Gade A, Johannsen P, Rossor M, Thusgaard T, Grove A, Yancopoulou D, Spillantini MG, Fisher EM, Collinge J, Sorensen SA. Chromosome 3 linked frontotemporal dementia (FTD-3). Neurology. 59: 1585-94. PMID 12451202 DOI: 10.1212/01.Wnl.0000034763.54161.1F |
0.355 |
|
| 2002 |
Allen B, Ingram E, Takao M, Smith MJ, Jakes R, Virdee K, Yoshida H, Holzer M, Craxton M, Emson PC, Atzori C, Migheli A, Crowther RA, Ghetti B, Spillantini MG, et al. Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9340-51. PMID 12417659 DOI: 10.1523/Jneurosci.22-21-09340.2002 |
0.506 |
|
| 2002 |
David DC, Layfield R, Serpell L, Narain Y, Goedert M, Spillantini MG. Proteasomal degradation of tau protein. Journal of Neurochemistry. 83: 176-85. PMID 12358741 DOI: 10.1046/J.1471-4159.2002.01137.X |
0.444 |
|
| 2002 |
Layfield R, Tofaris GK, Mee MP, Bailey K, Spillantini MG. 20S Proteasomal degradation of α-synuclein does not generate the non-β-amyloid plaque component (NAC) Biochemical Society Transactions. 30. DOI: 10.1042/Bst030A077C |
0.306 |
|
| 2001 |
Tofaris GK, Layfield R, Spillantini MG. alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome. Febs Letters. 509: 22-6. PMID 11734199 DOI: 10.1016/S0014-5793(01)03115-5 |
0.39 |
|
| 2001 |
Spillantini MG, Goedert M. Tau and Parkinson disease. Jama. 286: 2324-6. PMID 11710900 DOI: 10.1001/Jama.286.18.2324 |
0.472 |
|
| 2001 |
Neumann M, Schulz-Schaeffer W, Crowther RA, Smith MJ, Spillantini MG, Goedert M, Kretzschmar HA. Pick's disease associated with the novel Tau gene mutation K369I. Annals of Neurology. 50: 503-13. PMID 11601501 DOI: 10.1002/Ana.1223 |
0.541 |
|
| 2001 |
Rosso SM, Kamphorst W, de Graaf B, Willemsen R, Ravid R, Niermeijer MF, Spillantini MG, Heutink P, van Swieten JC. Familial frontotemporal dementia with ubiquitin-positive inclusions is linked to chromosome 17q21-22. Brain : a Journal of Neurology. 124: 1948-57. PMID 11571213 DOI: 10.1093/Brain/124.10.1948 |
0.464 |
|
| 2001 |
Goedert M, Spillantini MG. Tau gene mutations and neurodegeneration. Biochemical Society Symposium. 59-71. PMID 11447840 DOI: 10.1042/Bss0670059 |
0.524 |
|
| 2001 |
Spillantini MG, Goedert M. Tau gene mutations and tau pathology in frontotemporal dementia and parkinsonism linked to chromosome 17. Advances in Experimental Medicine and Biology. 487: 21-37. PMID 11403160 DOI: 10.1007/978-1-4615-1249-3_3 |
0.525 |
|
| 2001 |
Goedert M, Spillantini MG, Serpell LC, Berriman J, Smith MJ, Jakes R, Crowther RA. From genetics to pathology: tau and alpha-synuclein assemblies in neurodegenerative diseases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 213-27. PMID 11260802 DOI: 10.1098/Rstb.2000.0767 |
0.509 |
|
| 2000 |
Goedert M, Ghetti B, Spillantini MG. Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Their relevance for understanding the neurogenerative process. Annals of the New York Academy of Sciences. 920: 74-83. PMID 11193179 DOI: 10.1111/J.1749-6632.2000.Tb06907.X |
0.544 |
|
| 2000 |
Ghetti B, Murrell JR, Zolo P, Spillantini MG, Goedert M. Progress in hereditary tauopathies: a mutation in the Tau gene (G389R) causes a Pick disease-like syndrome. Annals of the New York Academy of Sciences. 920: 52-62. PMID 11193177 DOI: 10.1111/J.1749-6632.2000.Tb06905.X |
0.506 |
|
| 2000 |
Spillantini MG, Goedert M. The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Annals of the New York Academy of Sciences. 920: 16-27. PMID 11193145 DOI: 10.1111/J.1749-6632.2000.Tb06900.X |
0.448 |
|
| 2000 |
Spillantini MG, Yoshida H, Rizzini C, Lantos PL, Khan N, Rossor MN, Goedert M, Brown J. A novel tau mutation (N296N) in familial dementia with swollen achromatic neurons and corticobasal inclusion bodies. Annals of Neurology. 48: 939-43. PMID 11117553 DOI: 10.1002/1531-8249(200012)48:6<939::Aid-Ana17>3.0.Co;2-1 |
0.497 |
|
| 2000 |
Rizzini C, Goedert M, Hodges JR, Smith MJ, Jakes R, Hills R, Xuereb JH, Crowther RA, Spillantini MG. Tau gene mutation K257T causes a tauopathy similar to Pick's disease. Journal of Neuropathology and Experimental Neurology. 59: 990-1001. PMID 11089577 DOI: 10.1093/Jnen/59.11.990 |
0.518 |
|
| 2000 |
Spillantini MG, Van Swieten JC, Goedert M. Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Neurogenetics. 2: 193-205. PMID 10983715 DOI: 10.1007/Pl00022972 |
0.535 |
|
| 2000 |
Tolnay M, Spillantini MG, Rizzini C, Eccles D, Lowe J, Ellison D. A new case of frontotemporal dementia and parkinsonism resulting from an intron 10 + 3-splice site mutation in the tau gene: Clinical and pathological features Neuropathology and Applied Neurobiology. 26: 368-378. PMID 10931371 DOI: 10.1046/j.1365-2990.2000.00109.x |
0.319 |
|
| 2000 |
Goedert M, Spillantini MG. Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease. Biochimica Et Biophysica Acta. 1502: 110-21. PMID 10899436 DOI: 10.1016/S0925-4439(00)00037-5 |
0.553 |
|
| 2000 |
Probst A, Götz J, Wiederhold KH, Tolnay M, Mistl C, Jaton AL, Hong M, Ishihara T, Lee VM, Trojanowski JQ, Jakes R, Crowther RA, Spillantini MG, Bürki K, Goedert M. Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathologica. 99: 469-81. PMID 10805089 DOI: 10.1007/S004010051148 |
0.458 |
|
| 2000 |
Spillantini MG, Goedert M. Tau mutations in familial frontotemporal dementia. Brain : a Journal of Neurology. 123: 857-9. PMID 10775532 DOI: 10.1093/Brain/123.5.857 |
0.494 |
|
| 2000 |
Yasuda M, Takamatsu J, D'Souza I, Crowther RA, Kawamata T, Hasegawa M, Hasegawa H, Spillantini MG, Tanimukai S, Poorkaj P, Varani L, Varani G, Iwatsubo T, Goedert M, Schellenberg DG, et al. A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto) Annals of Neurology. 47: 422-9. PMID 10762152 DOI: 10.1002/1531-8249(200004)47:4<422::Aid-Ana4>3.0.Co;2-G |
0.476 |
|
| 2000 |
Spillantini MG. Tau pathology in families with frontotemporal dementia and Parkinsonism linked to chromosome 17 Neurobiology of Aging. 21: 285. DOI: 10.1016/S0197-4580(00)83230-3 |
0.435 |
|
| 1999 |
Spillantini MG. Parkinson's disease, dementia with Lewy bodies and multiple system atrophy are alpha-synucleinopathies. Parkinsonism & Related Disorders. 5: 157-62. PMID 18591134 DOI: 10.1016/S1353-8020(99)00031-0 |
0.455 |
|
| 1999 |
Ghetti B, Murrell J, Spillantini MG. Mutations in the Tau gene cause frontotemporal dementia. Brain Research Bulletin. 50: 471-2. PMID 10643489 DOI: 10.1016/S0361-9230(99)00139-2 |
0.433 |
|
| 1999 |
Murrell JR, Spillantini MG, Zolo P, Guazzelli M, Smith MJ, Hasegawa M, Redi F, Crowther RA, Pietrini P, Ghetti B, Goedert M. Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits. Journal of Neuropathology and Experimental Neurology. 58: 1207-26. PMID 10604746 DOI: 10.1097/00005072-199912000-00002 |
0.504 |
|
| 1999 |
van Swieten JC, Stevens M, Rosso SM, Rizzu P, Joosse M, de Koning I, Kamphorst W, Ravid R, Spillantini MG, Niermeijer, Heutink P. Phenotypic variation in hereditary frontotemporal dementia with tau mutations. Annals of Neurology. 46: 617-26. PMID 10514099 DOI: 10.1002/1531-8249(199910)46:4<617::Aid-Ana10>3.0.Co;2-I |
0.457 |
|
| 1999 |
Hulette CM, Pericak-Vance MA, Roses AD, Schmechel DE, Yamaoka LH, Gaskell PC, Welsh-Bohmer KA, Crowther RA, Spillantini MG. Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684. Journal of Neuropathology and Experimental Neurology. 58: 859-66. PMID 10446810 DOI: 10.1097/00005072-199908000-00008 |
0.431 |
|
| 1999 |
Varani L, Hasegawa M, Spillantini MG, Smith MJ, Murrell JR, Ghetti B, Klug A, Goedert M, Varani G. Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proceedings of the National Academy of Sciences of the United States of America. 96: 8229-34. PMID 10393977 DOI: 10.1073/Pnas.96.14.8229 |
0.38 |
|
| 1999 |
Spillantini MG, Tolnay M, Love S, Goedert M. Microtubule-associated protein tau, heparan sulphate and alpha-synuclein in several neurodegenerative diseases with dementia. Acta Neuropathologica. 97: 585-94. PMID 10378377 DOI: 10.1007/S004010051034 |
0.521 |
|
| 1999 |
Bugiani O, Murrell JR, Giaccone G, Hasegawa M, Ghigo G, Tabaton M, Morbin M, Primavera A, Carella F, Solaro C, Grisoli M, Savoiardo M, Spillantini MG, Tagliavini F, Goedert M, et al. Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 667-77. PMID 10374757 DOI: 10.1097/00005072-199906000-00011 |
0.485 |
|
| 1999 |
Mirra SS, Murrell JR, Gearing M, Spillantini MG, Goedert M, Crowther RA, Levey AI, Jones R, Green J, Shoffner JM, Wainer BH, Schmidt ML, Trojanowski JQ, Ghetti B. Tau pathology in a family with dementia and a P301L mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 335-45. PMID 10218629 DOI: 10.1097/00005072-199904000-00004 |
0.525 |
|
| 1999 |
Goedert M, Spillantini MG, Crowther RA, Chen SG, Parchi P, Tabaton M, Lanska DJ, Markesbery WR, Wilhelmsen KC, Dickson DW, Petersen RB, Gambetti P. Tau gene mutation in familial progressive subcortical gliosis. Nature Medicine. 5: 454-7. PMID 10202939 DOI: 10.1038/7454 |
0.497 |
|
| 1999 |
Kimonides VG, Spillantini MG, Sofroniew MV, Fawcett JW, Herbert J. Dehydroepiandrosterone antagonizes the neurotoxic effects of corticosterone and translocation of stress-activated protein kinase 3 in hippocampal primary cultures. Neuroscience. 89: 429-36. PMID 10077325 DOI: 10.1016/S0306-4522(98)00347-9 |
0.304 |
|
| 1999 |
Zolo P, Spillantini MG, Crowter T, Redi F, Guazzelli M, Murrell J, Ghetti B. Pick Disease With Glial Tau Inclusions In The White Matter Journal of Neuropathology and Experimental Neurology. 58: 546. DOI: 10.1097/00005072-199905000-00159 |
0.42 |
|
| 1999 |
Spillantini MG. Parkinson's disease, dementia with Lewy bodies and multiple system atrophy are α-synucleinopathies Parkinsonism and Related Disorders. 5: 157-162. DOI: 10.1016/S1353-8020(99)00031-0 |
0.3 |
|
| 1998 |
Goedert M, Crowther RA, Spillantini MG. Tau mutations cause frontotemporal dementias. Neuron. 21: 955-8. PMID 9856453 DOI: 10.1016/S0896-6273(00)80615-7 |
0.445 |
|
| 1998 |
Goedert M, Spillantini MG, Davies SW. Filamentous nerve cell inclusions in neurodegenerative diseases. Current Opinion in Neurobiology. 8: 619-32. PMID 9811617 DOI: 10.1016/S0959-4388(98)80090-1 |
0.498 |
|
| 1998 |
Spillantini MG, Crowther RA, Kamphorst W, Heutink P, van Swieten JC. Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau. The American Journal of Pathology. 153: 1359-63. PMID 9811325 DOI: 10.1016/S0002-9440(10)65721-5 |
0.511 |
|
| 1998 |
Crowther RA, Jakes R, Spillantini MG, Goedert M. Synthetic filaments assembled from C-terminally truncated alpha-synuclein. Febs Letters. 436: 309-12. PMID 9801138 DOI: 10.1016/S0014-5793(98)01146-6 |
0.398 |
|
| 1998 |
Spillantini MG, Goedert M. Tau protein pathology in neurodegenerative diseases. Trends in Neurosciences. 21: 428-33. PMID 9786340 DOI: 10.1016/S0166-2236(98)01337-X |
0.544 |
|
| 1998 |
Goedert M, Jakes R, Crowther RA, Hasegawa M, Smith MJ, Spillantini MG. Intraneuronal filamentous tau protein and alpha-synuclein deposits in neurodegenerative diseases. Biochemical Society Transactions. 26: 463-71. PMID 9765897 DOI: 10.1042/Bst0260463 |
0.444 |
|
| 1998 |
Spillantini MG, Crowther RA, Jakes R, Cairns NJ, Lantos PL, Goedert M. Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neuroscience Letters. 251: 205-8. PMID 9726379 DOI: 10.1016/S0304-3940(98)00504-7 |
0.429 |
|
| 1998 |
Spillantini MG, Murrell JR, Goedert M, Farlow MR, Klug A, Ghetti B. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proceedings of the National Academy of Sciences of the United States of America. 95: 7737-41. PMID 9636220 DOI: 10.1073/Pnas.95.13.7737 |
0.514 |
|
| 1998 |
Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proceedings of the National Academy of Sciences of the United States of America. 95: 6469-73. PMID 9600990 DOI: 10.1073/Pnas.95.11.6469 |
0.415 |
|
| 1998 |
Spillantini MG, Bird TD, Ghetti B. Frontotemporal dementia and Parkinsonism linked to chromosome 17: a new group of tauopathies. Brain Pathology (Zurich, Switzerland). 8: 387-402. PMID 9546295 DOI: 10.1111/J.1750-3639.1998.Tb00162.X |
0.491 |
|
| 1998 |
Lowe J, Spillantini MG. Non-Alzheimer degenerative dementias. Brain Pathology (Zurich, Switzerland). 8: 295-7. PMID 9546288 DOI: 10.1111/J.1750-3639.1998.Tb00155.X |
0.395 |
|
| 1997 |
Murrell JR, Koller D, Foroud T, Goedert M, Spillantini MG, Edenberg HJ, Farlow MR, Ghetti B. Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17. American Journal of Human Genetics. 61: 1131-8. PMID 9345089 DOI: 10.1086/301594 |
0.387 |
|
| 1997 |
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature. 388: 839-40. PMID 9278044 DOI: 10.1038/42166 |
0.454 |
|
| 1997 |
Tolnay M, Spillantini MG, Goedert M, Ulrich J, Langui D, Probst A. Argyrophilic grain disease: widespread hyperphosphorylation of tau protein in limbic neurons. Acta Neuropathologica. 93: 477-84. PMID 9144586 DOI: 10.1007/S004010050642 |
0.487 |
|
| 1997 |
Spillantini MG, Goedert M, Crowther RA, Murrell JR, Farlow MR, Ghetti B. Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proceedings of the National Academy of Sciences of the United States of America. 94: 4113-8. PMID 9108114 DOI: 10.1073/Pnas.94.8.4113 |
0.53 |
|
| 1997 |
Chevallier N, Vizzavona J, Marambaud P, Baur CP, Spillantini M, Fulcrand P, Martinez J, Goedert M, Vincent JP, Checler F. Cathepsin D displays in vitro beta-secretase-like specificity. Brain Research. 750: 11-9. PMID 9098524 DOI: 10.1016/S0006-8993(96)01330-3 |
0.339 |
|
| 1996 |
Goedert M, Spillantini MG, Hasegawa M, Jakes R, Crowther RA, Klug A. Molecular dissection of the neurofibrillary lesions of Alzheimer's disease. Cold Spring Harbor Symposia On Quantitative Biology. 61: 565-73. PMID 9246483 DOI: 10.1101/Sqb.1996.061.01.057 |
0.353 |
|
| 1996 |
Probst A, Tolnay M, Langui D, Goedert M, Spillantini MG. Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment. Acta Neuropathologica. 92: 588-96. PMID 8960316 DOI: 10.1007/S004010050565 |
0.504 |
|
| 1996 |
Goedert M, Jakes R, Spillantini MG, Hasegawa M, Smith MJ, Crowther RA. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature. 383: 550-3. PMID 8849730 DOI: 10.1038/383550A0 |
0.499 |
|
| 1996 |
Spillantini MG, Crowther RA, Goedert M. Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles. Acta Neuropathologica. 92: 42-8. PMID 8811124 DOI: 10.1007/S004010050487 |
0.49 |
|
| 1996 |
Ghetti B, Piccardo P, Spillantini MG, Ichimiya Y, Porro M, Perini F, Kitamoto T, Tateishi J, Seiler C, Frangione B, Bugiani O, Giaccone G, Prelli F, Goedert M, Dlouhy SR, et al. Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. Proceedings of the National Academy of Sciences of the United States of America. 93: 744-8. PMID 8570627 DOI: 10.1073/Pnas.93.2.744 |
0.453 |
|
| 1996 |
Ghetti B, Farlow MR, Crowther RA, Goedert M, Spillantini MG. HEREDITARY MULTIPLE SYSTEM DEGENERATION WITH PRESENILE DEMENTIA Journal of Neuropathology and Experimental Neurology. 55: 608. DOI: 10.1097/00005072-199605000-00026 |
0.38 |
|
| 1996 |
Spillantini MG, Goedert M, Crowther RA, Ghetti B. 638 Characterization of tau-positive fibrillary pathology in familial multiple system degeneration with presenile dementia Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80640-3 |
0.441 |
|
| 1995 |
Goedert M, Jakes R, Spillantini MG, Crowther RA, Cohen P, Vanmechelen E, Probst A, Götz J, Bürki K. Tau protein in Alzheimer's disease. Biochemical Society Transactions. 23: 80-5. PMID 7758799 DOI: 10.1042/Bst0230080 |
0.474 |
|
| 1995 |
Götz J, Probst A, Spillantini MG, Schäfer T, Jakes R, Bürki K, Goedert M. Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. The Embo Journal. 14: 1304-13. PMID 7729409 DOI: 10.1002/J.1460-2075.1995.Tb07116.X |
0.497 |
|
| 1995 |
Goedert M, Spillantini MG, Jakes R, Crowther RA, Vanmechelen E, Probst A, Götz J, Bürki K, Cohen P. Molecular dissection of the paired helical filament. Neurobiology of Aging. 16: 325-34. PMID 7566342 DOI: 10.1016/0197-4580(95)00017-9 |
0.453 |
|
| 1995 |
Spillantini MG, Divane A, Goedert M. Assignment of human alpha-synuclein (SNCA) and beta-synuclein (SNCB) genes to chromosomes 4q21 and 5q35. Genomics. 27: 379-81. PMID 7558013 DOI: 10.1006/Geno.1995.1063 |
0.37 |
|
| 1994 |
Jakes R, Spillantini MG, Goedert M. Identification of two distinct synucleins from human brain. Febs Letters. 345: 27-32. PMID 8194594 DOI: 10.1016/0014-5793(94)00395-5 |
0.364 |
|
| 1992 |
Goedert M, Spillantini MG, Crowther RA. Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America. 89: 1983-7. PMID 1542696 DOI: 10.1073/Pnas.89.5.1983 |
0.415 |
|
| 1992 |
Goedert M, Spillantini MG, Cairns NJ, Crowther RA. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron. 8: 159-68. PMID 1530909 DOI: 10.1016/0896-6273(92)90117-V |
0.447 |
|
| 1991 |
Goedert M, Spillantini MG, Jakes R. Localization of the Alz-50 epitope in recombinant human microtubule-associated protein tau. Neuroscience Letters. 126: 149-54. PMID 1717895 DOI: 10.1016/0304-3940(91)90541-Z |
0.495 |
|
| 1991 |
Goedert M, Spillantini MG, Crowther RA. Tau proteins and neurofibrillary degeneration. Brain Pathology (Zurich, Switzerland). 1: 279-86. PMID 1669718 DOI: 10.1111/J.1750-3639.1991.Tb00671.X |
0.476 |
|
| 1990 |
Spillantini MG, Goedert M, Jakes R, Klug A. Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 87: 3947-51. PMID 2111023 DOI: 10.1073/Pnas.87.10.3947 |
0.353 |
|
| 1990 |
Goedert M, Spillantini MG. Molecular neuropathology of Alzheimer's disease: in situ hybridization studies. Cellular and Molecular Neurobiology. 10: 159-74. PMID 2110505 DOI: 10.1007/Bf00733642 |
0.453 |
|
| 1990 |
Spillantini MG, Goedert M, Jakes R, Klug A. Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 87: 3952-6. PMID 1692627 DOI: 10.1073/Pnas.87.10.3952 |
0.434 |
|
| 1989 |
Spillantini MG, Hunt SP, Ulrich J, Goedert M. Expression and cellular localization of amyloid beta-protein precursor transcripts in normal human brain and in Alzheimer's disease. Brain Research. Molecular Brain Research. 6: 143-50. PMID 2515408 DOI: 10.1016/0169-328X(89)90048-X |
0.371 |
|
| 1989 |
Goedert M, Spillantini MG, Potier MC, Ulrich J, Crowther RA. Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. The Embo Journal. 8: 393-9. PMID 2498079 DOI: 10.1002/J.1460-2075.1989.Tb03390.X |
0.404 |
|
| 1989 |
Goedert M, Spillantini MG, Jakes R, Rutherford D, Crowther RA. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron. 3: 519-26. PMID 2484340 DOI: 10.1016/0896-6273(89)90210-9 |
0.438 |
|
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