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Simonetta Sipione - Publications

Affiliations: 
Pharmacology University of Alberta, Edmonton, Alberta, Canada 
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Steinberg N, Galleguillos D, Zaidi A, Horkey M, Sipione S. Naïve Huntington's disease microglia mount a normal response to inflammatory stimuli but display a partially impaired development of innate immune tolerance that can be counteracted by ganglioside GM1. Journal of Neuroinflammation. 20: 276. PMID 37996924 DOI: 10.1186/s12974-023-02963-y  0.72
2022 de Almeida MMA, Watson AES, Bibi S, Dittmann NL, Goodkey K, Sharafodinzadeh P, Galleguillos D, Nakhaei-Nejad M, Kosaraju J, Steinberg N, Wang BS, Footz T, Giuliani F, Wang J, Sipione S, et al. Fractalkine enhances oligodendrocyte regeneration and remyelination in a demyelination mouse model. Stem Cell Reports. PMID 36608690 DOI: 10.1016/j.stemcr.2022.12.001  0.714
2022 Galleguillos D, Wang Q, Steinberg N, Zaidi A, Shrivastava G, Dhami K, Daskhan GC, Schmidt EN, Dworsky-Fried Z, Giuliani F, Churchward M, Power C, Todd K, Taylor A, Macauley MS, ... Sipione S, et al. Anti-inflammatory role of GM1 and other gangliosides on microglia. Journal of Neuroinflammation. 19: 9. PMID 34991625 DOI: 10.1186/s12974-021-02374-x  0.741
2021 Watson AES, de Almeida MMA, Dittmann NL, Li Y, Torabi P, Footz T, Vetere G, Galleguillos D, Sipione S, Cardona AE, Voronova A. Fractalkine signaling regulates oligodendroglial cell genesis from SVZ precursor cells. Stem Cell Reports. PMID 34270934 DOI: 10.1016/j.stemcr.2021.06.010  0.73
2020 Bhattacherjee A, Rodrigues E, Jung J, Luzentales-Simpson M, Enterina JR, Galleguillos D, St Laurent CD, Nakhaei-Nejad M, Fuchsberger FF, Streith L, Wang Q, Kawasaki N, Duan S, Bains A, Paulson JC, ... ... Sipione S, et al. Author Correction: Repression of phagocytosis by human CD33 is not conserved with mouse CD33. Communications Biology. 3: 36. PMID 33446800 DOI: 10.1038/s42003-020-0769-8  0.686
2020 Sipione S, Monyror J, Galleguillos D, Steinberg N, Kadam V. Gangliosides in the Brain: Physiology, Pathophysiology and Therapeutic Applications. Frontiers in Neuroscience. 14: 572965. PMID 33117120 DOI: 10.3389/fnins.2020.572965  0.724
2020 Bhattacherjee A, Rodrigues E, Jung J, Luzentales-Simpson M, Enterina JR, Galleguillos D, St Laurent CD, Nakhaei-Nejad M, Fuchsberger FF, Streith L, Wang Q, Kawasaki N, Duan S, Bains A, Paulson JC, ... ... Sipione S, et al. Erratum: Author Correction: Repression of phagocytosis by human CD33 is not conserved with mouse CD33. Communications Biology. 3: 36. PMID 31970292 DOI: 10.1038/s42003-020-0769-8  0.689
2019 Di Pardo A, Monyror J, Morales LC, Kadam V, Lingrell S, Maglione V, Wozniak RW, Sipione S. Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import. Human Molecular Genetics. PMID 31875875 DOI: 10.1093/Hmg/Ddz298  0.386
2019 Bhattacherjee A, Rodrigues E, Jung J, Luzentales-Simpson M, Enterina JR, Galleguillos D, St Laurent CD, Nakhaei-Nejad M, Fuchsberger FF, Streith L, Wang Q, Kawasaki N, Duan S, Bains A, Paulson JC, ... ... Sipione S, et al. Repression of phagocytosis by human CD33 is not conserved with mouse CD33. Communications Biology. 2: 450. PMID 31815204 DOI: 10.1038/s42003-019-0698-6  0.726
2019 Magistretti PJ, Geisler FH, Schneider JS, Li PA, Fiumelli H, Sipione S. Gangliosides: Treatment Avenues in Neurodegenerative Disease. Frontiers in Neurology. 10: 859. PMID 31447771 DOI: 10.3389/Fneur.2019.00859  0.353
2019 van der Veen JN, Lingrell S, McCloskey N, LeBlond ND, Galleguillos D, Zhao YY, Curtis JM, Sipione S, Fullerton MD, Vance DE, Jacobs RL. A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802117R. PMID 30615497 DOI: 10.1096/Fj.201802117R  0.693
2018 Bowie LE, Maiuri T, Alpaugh M, Gabriel M, Arbez N, Galleguillos D, Hung CLK, Patel S, Xia J, Hertz NT, Ross CA, Litchfield DW, Sipione S, Truant R. N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987005 DOI: 10.1073/Pnas.1801772115  0.713
2017 Alpaugh M, Galleguillos D, Forero J, Morales LC, Lackey SW, Kar P, Di Pardo A, Holt A, Kerr BJ, Todd KG, Baker GB, Fouad K, Sipione S. Disease-modifying effects of ganglioside GM1 in Huntington's disease models. Embo Molecular Medicine. PMID 28993428 DOI: 10.15252/Emmm.201707763  0.731
2016 Wei D, Hurd C, Galleguillos D, Singh J, Fenrich KK, Webber CA, Sipione S, Fouad K. Inhibiting cortical protein kinase a in spinal cord injured rats enhances efficacy of rehabilitative training. Experimental Neurology. PMID 27401133 DOI: 10.1016/J.Expneurol.2016.07.001  0.712
2015 Sipione S, Rigamonti D, Valenza M, Zuccato C, Conti L, Pritchard J, Kooperberg C, Olson JM, Cattaneo E. Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Human Molecular Genetics. PMID 26577153 DOI: 10.1093/Hmg/Ddv416  0.553
2014 Sipione S, Rigamonti D, Valenza M, Zuccato C, Conti L, Pritchard J, Kooperberg C, Olson JM, Cattaneo E. Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Human Molecular Genetics. PMID 25416283 DOI: 10.1093/Hmg/Ddu539  0.52
2014 Weishaupt N, Mason AL, Hurd C, May Z, Zmyslowski DC, Galleguillos D, Sipione S, Fouad K. Vector-induced NT-3 expression in rats promotes collateral growth of injured corticospinal tract axons far rostral to a spinal cord injury. Neuroscience. 272: 65-75. PMID 24814724 DOI: 10.1016/J.Neuroscience.2014.04.041  0.696
2012 Mohamed A, Saavedra L, Di Pardo A, Sipione S, Posse de Chaves E. β-amyloid inhibits protein prenylation and induces cholesterol sequestration by impairing SREBP-2 cleavage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6490-500. PMID 22573671 DOI: 10.1523/Jneurosci.0630-12.2012  0.324
2012 Di Pardo A, Maglione V, Alpaugh M, Horkey M, Atwal RS, Sassone J, Ciammola A, Steffan JS, Fouad K, Truant R, Sipione S. Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 3528-33. PMID 22331905 DOI: 10.1073/Pnas.1114502109  0.36
2011 Atwal RS, Desmond CR, Caron N, Maiuri T, Xia J, Sipione S, Truant R. Kinase inhibitors modulate huntingtin cell localization and toxicity. Nature Chemical Biology. 7: 453-60. PMID 21623356 DOI: 10.1038/Nchembio.582  0.323
2011 Battaglia G, Cannella M, Riozzi B, Orobello S, Maat-Schieman ML, Aronica E, Busceti CL, Ciarmiello A, Alberti S, Amico E, Sassone J, Sipione S, Bruno V, Frati L, Nicoletti F, et al. Early defect of transforming growth factor β1 formation in Huntington's disease. Journal of Cellular and Molecular Medicine. 15: 555-71. PMID 20082658 DOI: 10.1111/J.1582-4934.2010.01011.X  0.311
2010 Sassone J, Colciago C, Marchi P, Ascardi C, Alberti L, Pardo AD, Zippel R, Sipione S, Silani V, Ciammola A. Mutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3) Cell Death and Disease. 1. PMID 21364626 DOI: 10.1038/Cddis.2009.6  0.384
2010 Maglione V, Marchi P, Di Pardo A, Lingrell S, Horkey M, Tidmarsh E, Sipione S. Impaired ganglioside metabolism in Huntington's disease and neuroprotective role of GM1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4072-80. PMID 20237277 DOI: 10.1523/Jneurosci.6348-09.2010  0.419
2010 Squitieri F, Battaglia G, Cannella M, Riozzi B, Orobello S, Maat-Schieman ML, Aronica E, Busceti CL, Ciarmiello A, Alberti S, Sassone J, Sipione S, Bruno V, Frati L, Nicoletti F. A19 Early defect of transforming growth factor β1 formation in Huntington's disease Journal of Neurology, Neurosurgery, and Psychiatry. 81. DOI: 10.1136/Jnnp.2010.222570.19  0.431
2010 Sassone J, Colciago C, Figini M, Marchi P, Colleoni F, Pardo AD, Zippel R, Torrente Y, Sipione S, Silani V, Ciammola A. A13 Mutant huntingtin induces activation of Bcl-2/adenovirus E1B 19-kDa interacting protein (BNIP3) Journal of Neurology, Neurosurgery, and Psychiatry. 81. DOI: 10.1136/Jnnp.2010.222570.13  0.373
2010 Battaglia G, Cannella M, Riozzi B, Orobello S, Maat-Schieman ML, Aronica E, Busceti CL, Ciarmiello A, Alberti S, Sassone J, Sipione S, Bruno V, Frati L, Nicoletti F, Squitieri F. Platform presentation—Early Defect of Transforming Growth Factor β1 Formation in Huntington's Disease Neurotherapeutics. 7: 135-136. DOI: 10.1016/J.Nurt.2009.09.025  0.436
2005 Valenza M, Rigamonti D, Goffredo D, Zuccato C, Fenu S, Jamot L, Strand A, Tarditi A, Woodman B, Racchi M, Mariotti C, Di Donato S, Corsini A, Bates G, Pruss R, ... ... Sipione S, et al. Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9932-9. PMID 16251441 DOI: 10.1523/Jneurosci.3355-05.2005  0.595
2005 Sipione S, Ewen C, Shostak I, Michalak M, Bleackley RC. Impaired cytolytic activity in calreticulin-deficient CTLs. Journal of Immunology (Baltimore, Md. : 1950). 174: 3212-9. PMID 15749851 DOI: 10.4049/Jimmunol.174.6.3212  0.342
2004 Sipione S, Eshpeter A, Lyon JG, Korbutt GS, Bleackley RC. Insulin expressing cells from differentiated embryonic stem cells are not beta cells. Diabetologia. 47: 499-508. PMID 14968299 DOI: 10.1007/S00125-004-1349-Z  0.301
2003 Barresi V, Belluardo N, Sipione S, Mudó G, Cattaneo E, Condorelli DF. Transplantation of prodrug-converting neural progenitor cells for brain tumor therapy Cancer Gene Therapy. 10: 396-402. PMID 12719709 DOI: 10.1038/Sj.Cgt.7700580  0.533
2003 Anfuso CD, Sipione S, Lupo G, Ragusa N, Alberghina M. Characterization of glycerophosphocholine phosphodiesterase activity and phosphatidylcholine biosynthesis in cultured retinal microcapillary pericytes. Effect of adenosine and endothelin-1. Lipids. 38: 45-52. PMID 12669819 DOI: 10.1007/S11745-003-1030-Z  0.303
2002 Kooperberg C, Sipione S, LeBlanc M, Strand AD, Cattaneo E, Olson JM. Evaluating test statistics to select interesting genes in microarray experiments. Human Molecular Genetics. 11: 2223-32. PMID 12217950 DOI: 10.1093/Hmg/11.19.2223  0.475
2002 Sipione S, Rigamonti D, Valenza M, Zuccato C, Conti L, Pritchard J, Kooperberg C, Olson JM, Cattaneo E. Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Human Molecular Genetics. 11: 1953-65. PMID 12165557 DOI: 10.1093/hmg/11.17.1953  0.506
2002 Sipione S, Cattaneo E. Modeling brain pathologies using neural stem cells. Methods in Molecular Biology (Clifton, N.J.). 198: 245-62. PMID 11951626 DOI: 10.1385/1-59259-186-8:245  0.526
2002 Sipione S, Cattaneo E. Modeling Huntington's disease in cells, flies, and mice. Molecular Neurobiology. 23: 21-51. PMID 11642542 DOI: 10.1385/Mn:23:1:21  0.593
2001 Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, MacDonald ME, Friedlander RM, Silani V, Hayden MR, Timmusk T, Sipione S, Cattaneo E. Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science (New York, N.Y.). 293: 493-8. PMID 11408619 DOI: 10.1126/Science.1059581  0.566
2001 Conti L, Sipione S, Magrassi L, Bonfanti L, Rigamonti D, Pettirossi V, Peschanski M, Haddad B, Pelicci P, Milanesi G, Pelicci G, Cattaneo E. Shc signaling in differentiating neural progenitor cells. Nature Neuroscience. 4: 579-86. PMID 11369938 DOI: 10.1038/88395  0.537
2001 Rigamonti D, Sipione S, Goffredo D, Zuccato C, Fossale E, Cattaneo E. Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing. The Journal of Biological Chemistry. 276: 14545-8. PMID 11278258 DOI: 10.1074/Jbc.C100044200  0.579
2001 Cattaneo E, Rigamonti D, Goffredo D, Zuccato C, Squitieri F, Sipione S. Loss of normal huntingtin function: new developments in Huntington's disease research. Trends in Neurosciences. 24: 182-8. PMID 11182459 DOI: 10.1016/S0166-2236(00)01721-5  0.548
2001 Ehrlich ME, Conti L, Toselli M, Taglietti L, Fiorillo E, Taglietti V, Ivkovic S, Guinea B, Tranberg A, Sipione S, Rigamonti D, Cattaneo E. ST14A cells have properties of a medium-size spiny neuron. Experimental Neurology. 167: 215-26. PMID 11161610 DOI: 10.1006/Exnr.2000.7551  0.553
2001 Varani K, Rigamonti D, Sipione S, Camurri A, Borea PA, Cattabeni F, Abbracchio MP, Cattaneo E. Aberrant amplification of A 2A receptor signaling in striatal cells expressing mutant huntingtin The Faseb Journal. 15: 1245-1247. DOI: 10.1096/Fj.00-0730Fje  0.562
2000 Rigamonti D, Bauer JH, De-Fraja C, Conti L, Sipione S, Sciorati C, Clementi E, Hackam A, Hayden MR, Li Y, Cooper JK, Ross CA, Govoni S, Vincenz C, Cattaneo E. Wild-Type Huntingtin Protects from Apoptosis Upstream of Caspase-3 The Journal of Neuroscience. 20: 3705-3713. DOI: 10.1523/Jneurosci.20-10-03705.2000  0.559
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