| Year |
Citation |
Score |
| 2021 |
Carmy-Bennun T, Myer C, Bhattacharya SK, Hackam AS. Quantitative proteomic analysis after neuroprotective MyD88 inhibition in the retinal degeneration 10 mouse. Journal of Cellular and Molecular Medicine. PMID 34562309 DOI: 10.1111/jcmm.16893 |
0.32 |
|
| 2020 |
Musada GR, Dvoriantchikova G, Myer C, Ivanov D, Bhattacharya SK, Hackam AS. The effect of extrinsic Wnt/β-catenin signaling in Muller glia on retinal ganglion cell (RGC) neurite growth. Developmental Neurobiology. PMID 32267608 DOI: 10.1002/Dneu.22741 |
0.377 |
|
| 2020 |
Garces K, Carmy T, Illiano P, Brambilla R, Hackam AS. Increased Neuroprotective Microglia and Photoreceptor Survival in the Retina from a Peptide Inhibitor of Myeloid Differentiation Factor 88 (MyD88). Journal of Molecular Neuroscience : Mn. PMID 32072483 DOI: 10.1007/S12031-020-01503-0 |
0.365 |
|
| 2019 |
Udeh A, Dvoriantchikova G, Carmy T, Ivanov D, Hackam AS. Wnt signaling induces neurite outgrowth in mouse retinal ganglion cells. Experimental Eye Research. PMID 30879996 DOI: 10.1016/J.Exer.2019.03.004 |
0.354 |
|
| 2016 |
Patel AK, Park KK, Hackam AS. Wnt signaling promotes axonal regeneration following optic nerve injury in the mouse. Neuroscience. PMID 28011153 DOI: 10.1016/J.Neuroscience.2016.12.020 |
0.312 |
|
| 2015 |
Patel AK, Davis A, Rodriguez ME, Agron S, Hackam AS. Protective effects of a grape-supplemented diet in a mouse model of retinal degeneration. Nutrition (Burbank, Los Angeles County, Calif.). PMID 26732835 DOI: 10.1016/J.Nut.2015.09.017 |
0.387 |
|
| 2015 |
Seigel GM, Sharma S, Hackam AS, Shah DK. HER2/ERBB2 immunoreactivity in human retinoblastoma. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 26614428 DOI: 10.1007/S13277-015-4475-Y |
0.379 |
|
| 2015 |
Patel AK, Akinsoji E, Hackam AS. Defining the Relationships Among Retinal Function, Layer Thickness and Visual Behavior During Oxidative Stress-Induced Retinal Degeneration. Current Eye Research. 1-10. PMID 26554945 DOI: 10.3109/02713683.2015.1083588 |
0.368 |
|
| 2015 |
Syeda S, Patel AK, Lee T, Hackam AS. Reduced photoreceptor death and improved retinal function during retinal degeneration in mice lacking innate immunity adaptor protein MyD88. Experimental Neurology. 267: 1-12. PMID 25725353 DOI: 10.1016/J.Expneurol.2015.02.027 |
0.397 |
|
| 2015 |
Patel AK, Surapaneni K, Yi H, Nakamura RE, Karli SZ, Syeda S, Lee T, Hackam AS. Activation of Wnt/β-catenin signaling in Muller glia protects photoreceptors in a mouse model of inherited retinal degeneration. Neuropharmacology. 91: 1-12. PMID 25486619 DOI: 10.1016/J.Neuropharm.2014.11.015 |
0.379 |
|
| 2013 |
Patel AK, Syeda S, Hackam AS. Signal transducer and activator of transcription 3 (STAT3) signaling in retinal pigment epithelium cells. Jak-Stat. 2: e25434. PMID 24416648 DOI: 10.4161/jkst.25434 |
0.308 |
|
| 2013 |
Patel AK, Hackam AS. Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism. Molecular Immunology. 54: 122-31. PMID 23267850 DOI: 10.1016/J.Molimm.2012.11.005 |
0.343 |
|
| 2012 |
Fragoso MA, Patel AK, Nakamura RE, Yi H, Surapaneni K, Hackam AS. The Wnt/β-catenin pathway cross-talks with STAT3 signaling to regulate survival of retinal pigment epithelium cells. Plos One. 7: e46892. PMID 23056515 DOI: 10.1371/Journal.Pone.0046892 |
0.358 |
|
| 2012 |
Yi H, Patel AK, Sodhi CP, Hackam DJ, Hackam AS. Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis. Plos One. 7: e36560. PMID 22615780 DOI: 10.1371/Journal.Pone.0036560 |
0.326 |
|
| 2012 |
Yi H, Hu J, Qian J, Hackam AS. Expression of brain-derived neurotrophic factor is regulated by the Wnt signaling pathway. Neuroreport. 23: 189-94. PMID 22198686 DOI: 10.1097/Wnr.0B013E32834Fab06 |
0.347 |
|
| 2011 |
Fragoso MA, Yi H, Nakamura RE, Hackam AS. The Wnt signaling pathway protects retinal ganglion cell 5 (RGC-5) cells from elevated pressure. Cellular and Molecular Neurobiology. 31: 163-73. PMID 21061158 DOI: 10.1007/S10571-010-9603-Z |
0.417 |
|
| 2010 |
Nakamura RE, Hackam AS. Analysis of Dickkopf3 interactions with Wnt signaling receptors. Growth Factors (Chur, Switzerland). 28: 232-42. PMID 20370576 DOI: 10.3109/08977191003738832 |
0.32 |
|
| 2008 |
Hackam AS. Regulation of neurotrophin expression and activity in the retina. Advances in Experimental Medicine and Biology. 613: 343-9. PMID 18188963 DOI: 10.1007/978-0-387-74904-4_40 |
0.398 |
|
| 2007 |
Nakamura RE, Hunter DD, Yi H, Brunken WJ, Hackam AS. Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retina. Bmc Cell Biology. 8: 52. PMID 18093317 DOI: 10.1186/1471-2121-8-52 |
0.408 |
|
| 2007 |
Yi H, Nakamura RE, Mohamed O, Dufort D, Hackam AS. Characterization of Wnt signaling during photoreceptor degeneration. Investigative Ophthalmology & Visual Science. 48: 5733-41. PMID 18055826 DOI: 10.1167/Iovs.07-0097 |
0.391 |
|
| 2007 |
Ruggeri M, Wehbe H, Jiao S, Gregori G, Jockovich ME, Hackam A, Duan Y, Puliafito CA. In vivo three-dimensional high-resolution imaging of rodent retina with spectral-domain optical coherence tomography. Investigative Ophthalmology & Visual Science. 48: 1808-14. PMID 17389515 DOI: 10.1167/Iovs.06-0815 |
0.315 |
|
| 2007 |
Ruggeri M, Wehbe H, Jiao S, Gregori G, Jockovich ME, Hackam A, Duan Y, Puliafito CA. Spectral domain optical coherence tomography for in-vivo three dimensional retinal imaging of small animals Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6429. DOI: 10.1117/12.700437 |
0.354 |
|
| 2006 |
Tell S, Yi H, Jockovich ME, Murray TG, Hackam AS. The Wnt signaling pathway has tumor suppressor properties in retinoblastoma. Biochemical and Biophysical Research Communications. 349: 261-9. PMID 16930536 DOI: 10.1016/J.Bbrc.2006.08.044 |
0.337 |
|
| 2005 |
Hackam AS. The Wnt signaling pathway in retinal degenerations. Iubmb Life. 57: 381-8. PMID 16012046 DOI: 10.1080/15216540500137586 |
0.436 |
|
| 2004 |
Hackam AS, Qian J, Liu D, Gunatilaka T, Farkas RH, Chowers I, Kageyama M, Parmigiani G, Zack DJ. Comparative gene expression analysis of murine retina and brain. Molecular Vision. 10: 637-49. PMID 15359217 |
0.585 |
|
| 2004 |
Hackam AS, Strom R, Liu D, Qian J, Wang C, Otteson D, Gunatilaka T, Farkas RH, Chowers I, Kageyama M, Leveillard T, Sahel JA, Campochiaro PA, Parmigiani G, Zack DJ. Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse. Investigative Ophthalmology & Visual Science. 45: 2929-42. PMID 15326104 DOI: 10.1167/Iovs.03-1184 |
0.731 |
|
| 2004 |
Chowers I, Kim Y, Farkas RH, Gunatilaka TL, Hackam AS, Campochiaro PA, Finnemann SC, Zack DJ. Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake. Investigative Ophthalmology & Visual Science. 45: 2098-106. PMID 15223782 DOI: 10.1167/Iovs.03-0863 |
0.622 |
|
| 2004 |
Farkas RH, Chowers I, Hackam AS, Kageyama M, Nickells RW, Otteson DC, Duh EJ, Wang C, Valenta DF, Gunatilaka TL, Pease ME, Quigley HA, Zack DJ. Increased expression of iron-regulating genes in monkey and human glaucoma. Investigative Ophthalmology & Visual Science. 45: 1410-7. PMID 15111596 DOI: 10.1167/Iovs.03-0872 |
0.702 |
|
| 2003 |
Chowers I, Liu D, Farkas RH, Gunatilaka TL, Hackam AS, Bernstein SL, Campochiaro PA, Parmigiani G, Zack DJ. Gene expression variation in the adult human retina. Human Molecular Genetics. 12: 2881-93. PMID 14519682 DOI: 10.1093/Hmg/Ddg326 |
0.609 |
|
| 2003 |
Chowers I, Gunatilaka TL, Farkas RH, Qian J, Hackam AS, Duh E, Kageyama M, Wang C, Vora A, Campochiaro PA, Zack DJ. Identification of novel genes preferentially expressed in the retina using a custom human retina cDNA microarray. Investigative Ophthalmology & Visual Science. 44: 3732-41. PMID 12939286 DOI: 10.1167/Iovs.02-1080 |
0.625 |
|
| 2003 |
Hackam AS, Bradford RL, Bakhru RN, Shah RM, Farkas R, Zack DJ, Adler R. Gene discovery in the embryonic chick retina. Molecular Vision. 9: 262-76. PMID 12819621 |
0.581 |
|
| 2002 |
Gervais FG, Singaraja R, Xanthoudakis S, Gutekunst CA, Leavitt BR, Metzler M, Hackam AS, Tam J, Vaillancourt JP, Houtzager V, Rasper DM, Roy S, Hayden MR, Nicholson DW. Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nature Cell Biology. 4: 95-105. PMID 11788820 DOI: 10.1038/Ncb735 |
0.309 |
|
| 2000 |
Hackam AS, Yassa AS, Singaraja R, Metzler M, Gutekunst CA, Gan L, Warby S, Wellington CL, Vaillancourt J, Chen N, Gervais FG, Raymond L, Nicholson DW, Hayden MR. Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain. The Journal of Biological Chemistry. 275: 41299-308. PMID 11007801 DOI: 10.1074/Jbc.M008408200 |
0.313 |
|
| 2000 |
Rigamonti D, Bauer JH, De-Fraja C, Conti L, Sipione S, Sciorati C, Clementi E, Hackam A, Hayden MR, Li Y, Cooper JK, Ross CA, Govoni S, Vincenz C, Cattaneo E. Wild-Type Huntingtin Protects from Apoptosis Upstream of Caspase-3 The Journal of Neuroscience. 20: 3705-3713. DOI: 10.1523/Jneurosci.20-10-03705.2000 |
0.338 |
|
| 1999 |
Hackam AS, Hodgson JG, Singaraja R, Zhang T, Gan L, Gutekunst CA, Hersch SM, Hayden MR. Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 1047-55. PMID 10434304 DOI: 10.1098/Rstb.1999.0457 |
0.303 |
|
| 1999 |
Ellerby LM, Andrusiak RL, Wellington CL, Hackam AS, Propp SS, Wood JD, Sharp AH, Margolis RL, Ross CA, Salvesen GS, Hayden MR, Bredesen DE. Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity. The Journal of Biological Chemistry. 274: 8730-6. PMID 10085113 DOI: 10.1074/Jbc.274.13.8730 |
0.325 |
|
| 1999 |
Ellerby LM, Hackam AS, Propp SS, Ellerby HM, Rabizadeh S, Cashman NR, Trifiro MA, Pinsky L, Wellington CL, Salvesen GS, Hayden MR, Bredesen DE. Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity. Journal of Neurochemistry. 72: 185-95. PMID 9886069 DOI: 10.1046/J.1471-4159.1999.0720185.X |
0.315 |
|
| 1998 |
Hackam AS, Singaraja R, Wellington CL, Metzler M, McCutcheon K, Zhang T, Kalchman M, Hayden MR. The influence of huntingtin protein size on nuclear localization and cellular toxicity. The Journal of Cell Biology. 141: 1097-105. PMID 9606203 DOI: 10.1083/Jcb.141.5.1097 |
0.327 |
|
| 1998 |
Wellington CL, Ellerby LM, Hackam AS, Margolis RL, Trifiro MA, Singaraja R, McCutcheon K, Salvesen GS, Propp SS, Bromm M, Rowland KJ, Zhang T, Rasper D, Roy S, Thornberry N, et al. Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract. The Journal of Biological Chemistry. 273: 9158-67. PMID 9535906 DOI: 10.1074/Jbc.273.15.9158 |
0.328 |
|
| 1998 |
Martindale D, Hackam A, Wieczorek A, Ellerby L, Wellington C, McCutcheon K, Singaraja R, Kazemi-Esfarjani P, Devon R, Kim SU, Bredesen DE, Tufaro F, Hayden MR. Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates Nature Genetics. 18: 150-154. PMID 9462744 DOI: 10.1038/Ng0298-150 |
0.303 |
|
| 1997 |
Hackam AS, Wang TL, Guggino WB, Cutting GR. A 100 amino acid region in the GABA rho 1 subunit confers robust homo-oligomeric expression. Neuroreport. 8: 1425-30. PMID 9172147 DOI: 10.1097/00001756-199704140-00020 |
0.309 |
|
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