| Year |
Citation |
Score |
| 2017 |
Onfroy L, Galandrin S, Pontier SM, Seguelas MH, N'Guyen D, Sénard JM, Galés C. G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning. Scientific Reports. 7: 7885. PMID 28801617 DOI: 10.1038/s41598-017-07392-5 |
0.743 |
|
| 2016 |
Galandrin S, Denis C, Boularan C, Marie J, M'Kadmi C, Pilette C, Dubroca C, Nicaise Y, Seguelas MH, N'Guyen D, Banères JL, Pathak A, Sénard JM, Galés C. Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor. Hypertension (Dallas, Tex. : 1979). PMID 27698068 DOI: 10.1161/HYPERTENSIONAHA.116.08118 |
0.639 |
|
| 2016 |
Galandrin S, Onfroy L, Poirot MC, Sénard JM, Galés C. Delineating biased ligand efficacy at 7TM receptors from an experimental perspective. The International Journal of Biochemistry & Cell Biology. 77: 251-63. PMID 27107932 DOI: 10.1016/J.Biocel.2016.04.009 |
0.751 |
|
| 2015 |
Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, et al. The experimental power of FR900359 to study Gq-regulated biological processes. Nature Communications. 6: 10156. PMID 26658454 DOI: 10.1038/Ncomms10156 |
0.697 |
|
| 2015 |
Bellot M, Galandrin S, Boularan C, Matthies HJ, Despas F, Denis C, Javitch J, Mazères S, Sanni SJ, Pons V, Seguelas MH, Hansen JL, Pathak A, Galli A, Sénard JM, et al. Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling. Nature Chemical Biology. 11: 271-9. PMID 25706338 DOI: 10.1038/Nchembio.1766 |
0.72 |
|
| 2015 |
Damian M, Mary S, Maingot M, M'Kadmi C, Gagne D, Leyris JP, Denoyelle S, Gaibelet G, Gavara L, Garcia de Souza Costa M, Perahia D, Trinquet E, Mouillac B, Galandrin S, Galès C, et al. Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex. Proceedings of the National Academy of Sciences of the United States of America. 112: 1601-6. PMID 25605885 DOI: 10.1073/Pnas.1414618112 |
0.712 |
|
| 2013 |
van der Westhuizen E, Stallaert W, Murat B, Audet M, Galandrin S, Lagacé M, Bouvier M. Probing the Functional Selectivity of β-adrenergic Receptors Reveals New Signaling Modes and Potential Therapeutic Applications Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 112. DOI: 10.1016/B978-0-12-800044-1.00098-2 |
0.656 |
|
| 2012 |
Denis C, Saulière A, Galandrin S, Sénard JM, Galés C. Probing heterotrimeric G protein activation: applications to biased ligands. Current Pharmaceutical Design. 18: 128-44. PMID 22229559 DOI: 10.2174/138161212799040466 |
0.764 |
|
| 2008 |
Pontier SM, Percherancier Y, Galandrin S, Breit A, Galés C, Bouvier M. Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction. The Journal of Biological Chemistry. 283: 24659-72. PMID 18566454 DOI: 10.1074/Jbc.M800778200 |
0.67 |
|
| 2008 |
Galandrin S, Oligny-Longpré G, Bonin H, Ogawa K, Galés C, Bouvier M. Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor. Molecular Pharmacology. 74: 162-72. PMID 18403719 DOI: 10.1124/mol.107.043893 |
0.686 |
|
| 2007 |
Galandrin S, Oligny-Longpré G, Bouvier M. The evasive nature of drug efficacy: implications for drug discovery. Trends in Pharmacological Sciences. 28: 423-30. PMID 17659355 DOI: 10.1016/J.Tips.2007.06.005 |
0.598 |
|
| 2006 |
Galandrin S, Bouvier M. Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy. Molecular Pharmacology. 70: 1575-84. PMID 16901982 DOI: 10.1124/Mol.106.026716 |
0.604 |
|
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