Year |
Citation |
Score |
2022 |
Polinski NK, Martinez TN, Ramboz S, Sasner M, Herberth M, Switzer R, Ahmad SO, Pelligrino LJ, Clark SW, Marcus JN, Smith SM, Dave KD, Frasier MA. The GBA1 D409V mutation exacerbates synuclein pathology to differing extents in two alpha-synuclein models. Disease Models & Mechanisms. PMID 35419585 DOI: 10.1242/dmm.049192 |
0.38 |
|
2021 |
Polinski NK, Martinez TN, Gorodinsky A, Gareus R, Sasner M, Herberth M, Switzer R, Ahmad SO, Cosden M, Kandebo M, Drolet RE, Buckett PD, Shan W, Chen Y, Pellegrino LJ, et al. Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model. Plos One. 16: e0252325. PMID 34106956 DOI: 10.1371/journal.pone.0252325 |
0.713 |
|
2018 |
Mir R, Tonelli F, Lis P, Macartney T, Polinski NK, Martinez TN, Chou MY, Howden AJM, König T, Hotzy C, Milenkovic I, Brücke T, Zimprich A, Sammler E, Alessi DR. The Parkinson's disease VPS35[D620N] mutation enhances LRRK2 mediated Rab protein phosphorylation in mouse and human. The Biochemical Journal. PMID 29743203 DOI: 10.1042/Bcj20180248 |
0.385 |
|
2018 |
Polinski NK, Volpicelli-Daley LA, Sortwell CE, Luk KC, Cremades N, Gottler LM, Froula J, Duffy MF, Lee VM, Martinez TN, Dave KD. Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson's Disease in Rodents. Journal of Parkinson's Disease. PMID 29400668 DOI: 10.3233/Jpd-171248 |
0.512 |
|
2017 |
Purlyte E, Dhekne HS, Sarhan AR, Gomez R, Lis P, Wightman M, Martinez TN, Tonelli F, Pfeffer SR, Alessi DR. Rab29 activation of the Parkinson's disease-associated LRRK2 kinase. The Embo Journal. PMID 29212815 DOI: 10.15252/Embj.201798099 |
0.332 |
|
2017 |
Fan Y, Howden AJ, Sarhan AR, Lis P, Ito G, Martinez TN, Brockmann K, Gasser T, Alessi DR, Sammler EM. Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils. The Biochemical Journal. PMID 29127255 DOI: 10.1042/Bcj20170803 |
0.362 |
|
2017 |
Steger M, Diez F, Dhekne HS, Lis P, Nirujogi RS, Karayel O, Tonelli F, Martinez TN, Lorentzen E, Pfeffer SR, Alessi DR, Mann M. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. Elife. 6. PMID 29125462 DOI: 10.7554/Elife.31012 |
0.333 |
|
2014 |
Iacovitti L, Wei X, Cai J, Kostuk EW, Lin R, Gorodinsky A, Roman P, Kusek G, Das SS, Dufour A, Martinez TN, Dave KD. The hTH-GFP reporter rat model for the study of Parkinson's disease. Plos One. 9: e113151. PMID 25462571 DOI: 10.1371/Journal.Pone.0113151 |
0.604 |
|
2013 |
Nguyen TA, Frank-Cannon T, Martinez TN, Ruhn KA, Marvin M, Casey B, Treviño I, Hong JJ, Goldberg MS, Tansey MG. Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(-/-) mice. Journal of Neuroinflammation. 10: 50. PMID 23622116 DOI: 10.1186/1742-2094-10-50 |
0.772 |
|
2012 |
Martinez TN, Chen X, Bandyopadhyay S, Merrill AH, Tansey MG. Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons. Molecular Neurodegeneration. 7: 45. PMID 22973882 DOI: 10.1186/1750-1326-7-45 |
0.738 |
|
2012 |
Martinez TN, Greenamyre JT. Toxin models of mitochondrial dysfunction in Parkinson's disease. Antioxidants & Redox Signaling. 16: 920-34. PMID 21554057 DOI: 10.1089/ars.2011.4033 |
0.701 |
|
2008 |
Frank-Cannon TC, Tran T, Ruhn KA, Martinez TN, Hong J, Marvin M, Hartley M, Treviño I, O'Brien DE, Casey B, Goldberg MS, Tansey MG. Parkin deficiency increases vulnerability to inflammation-related nigral degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10825-34. PMID 18945890 DOI: 10.1523/Jneurosci.3001-08.2008 |
0.801 |
|
2008 |
McCoy MK, Ruhn KA, Martinez TN, McAlpine FE, Blesch A, Tansey MG. Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1572-9. PMID 18628756 DOI: 10.1038/Mt.2008.146 |
0.751 |
|
2008 |
McCoy MK, Martinez TN, Ruhn KA, Wrage PC, Keefer EW, Botterman BR, Tansey KE, Tansey MG. Autologous transplants of Adipose-Derived Adult Stromal (ADAS) cells afford dopaminergic neuroprotection in a model of Parkinson's disease. Experimental Neurology. 210: 14-29. PMID 18061169 DOI: 10.1016/J.Expneurol.2007.10.011 |
0.68 |
|
2008 |
Tansey MG, Frank-Cannon TC, McCoy MK, Lee JK, Martinez TN, McAlpine FE, Ruhn KA, Tran TA. Neuroinflammation in Parkinson's disease: is there sufficient evidence for mechanism-based interventional therapy? Frontiers in Bioscience : a Journal and Virtual Library. 13: 709-17. PMID 17981581 DOI: 10.2741/2713 |
0.639 |
|
2006 |
McCoy MK, Martinez TN, Ruhn KA, Szymkowski DE, Smith CG, Botterman BR, Tansey KE, Tansey MG. Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9365-75. PMID 16971520 DOI: 10.1523/Jneurosci.1504-06.2006 |
0.846 |
|
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