| Year |
Citation |
Score |
| 2023 |
de la Camara CM, Storm T, Salman A, Burgoyne T, Rasmussen MQ, Orlans HO, Russell AJ, Davies SG, Barnard AR, MacLaren RE. Developmental Expression of the Cell Cycle Regulator p16 in Retinal Glial Cells: A Novel Marker for Immature Ocular Astrocytes? The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 221554231184286. PMID 37350564 DOI: 10.1369/00221554231184286 |
0.303 |
|
| 2023 |
Josa-Culleré L, Galan SRG, Cogswell TJ, Jackson TR, Jay-Smith M, Mola L, Greaves CR, Carter TS, Madden KS, Trott S, Zhang D, Bataille CJR, Davies SG, Vyas P, Milne TA, ... ... Russell AJ, et al. Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines. European Journal of Medicinal Chemistry. 258: 115509. PMID 37343464 DOI: 10.1016/j.ejmech.2023.115509 |
0.656 |
|
| 2022 |
Jackson TR, Vuorinen A, Josa-Culleré L, Madden KS, Conole D, Cogswell TJ, Wilkinson IVL, Kettyle LM, Zhang D, O'Mahony A, Gracias D, McCall L, Westwood R, Terstappen GC, Davies SG, ... ... Russell AJ, et al. A tubulin binding molecule drives differentiation of acute myeloid leukemia cells. Iscience. 25: 104787. PMID 35992086 DOI: 10.1016/j.isci.2022.104787 |
0.362 |
|
| 2022 |
Balmforth D, Swales JA, Silpa L, Dunton A, Davies KE, Davies SG, Kamath A, Gupta J, Gupta S, Masood MA, McKnight Á, Rees D, Russell AJ, Jaggi M, Uppal R. Evaluating the efficacy and safety of a novel prophylactic nasal spray in the prevention of SARS-CoV-2 infection: A multi-centre, double blind, placebo-controlled, randomised trial. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 155: 105248. PMID 35952426 DOI: 10.1016/j.jcv.2022.105248 |
0.308 |
|
| 2022 |
Chatzopoulou M, Conole D, Emer E, Rowley JA, Willis NJ, Squire SE, Gill B, Brough S, Wilson FX, Wynne GM, Davies SG, Davies KE, Russell AJ. Structure-activity relationships of 2-pyrimidinecarbohydrazides as utrophin modulators for the potential treatment of Duchenne muscular dystrophy. Bioorganic & Medicinal Chemistry. 69: 116812. PMID 35772287 DOI: 10.1016/j.bmc.2022.116812 |
0.717 |
|
| 2021 |
Josa-Culleré L, Cogswell TJ, Georgiou I, Jay-Smith M, Jackson TR, Bataille CJR, Davies SG, Vyas P, Milne TA, Wynne GM, Russell AJ. Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[][1,4]oxazepin-2(3)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro. Molecules (Basel, Switzerland). 26. PMID 34771052 DOI: 10.3390/molecules26216648 |
0.373 |
|
| 2021 |
Josa-Culleré L, Madden KS, Cogswell TJ, Jackson TR, Carter TS, Zhang D, Trevitt G, Davies SG, Vyas P, Wynne GM, Milne TA, Russell AJ. A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells and Shows Antitumor Effects . Journal of Medicinal Chemistry. 64: 15608-15628. PMID 34672555 DOI: 10.1021/acs.jmedchem.1c00574 |
0.652 |
|
| 2021 |
Vuorinen A, Wilkinson IVL, Chatzopoulou M, Edwards B, Squire SE, Fairclough RJ, Bazan NA, Milner JA, Conole D, Donald JR, Shah N, Willis NJ, Martínez RF, Wilson FX, Wynne GM, ... ... Russell AJ, et al. Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy. European Journal of Medicinal Chemistry. 220: 113431. PMID 33915371 DOI: 10.1016/j.ejmech.2021.113431 |
0.381 |
|
| 2020 |
Chatzopoulou M, Emer E, Lecci C, Rowley JA, Casagrande AS, Moir L, Squire SE, Davies SG, Harriman S, Wynne GM, Wilson FX, Davies KE, Russell AJ. Decreasing HepG2 Cytotoxicity by Lowering the Lipophilicity of Benzo[d]oxazolephosphinate Ester Utrophin Modulators. Acs Medicinal Chemistry Letters. 11: 2421-2427. PMID 33335663 DOI: 10.1021/acsmedchemlett.0c00405 |
0.725 |
|
| 2020 |
Quevedo CE, Bataille CJR, Byrne S, Durbin M, Elkins J, Guillermo A, Jones AM, Knapp S, Nadali A, Walker RG, Wilkinson IVL, Wynne GM, Davies SG, Russell AJ. Aminothiazolones as potent, selective and cell active inhibitors of the PIM kinase family. Bioorganic & Medicinal Chemistry. 28: 115724. PMID 33128909 DOI: 10.1016/J.Bmc.2020.115724 |
0.441 |
|
| 2020 |
Babbs A, Berg A, Chatzopoulou M, Davies KE, Davies SG, Edwards B, Elsey DJ, Emer E, Figuccia ALA, Fletcher AM, Guiraud S, Harriman S, Moir L, Robinson N, Rowley JA, ... Russell AJ, et al. Synthesis of SMT022357 enantiomers and evaluation in a Duchenne muscular dystrophy mouse model. Tetrahedron. 76: 130819. PMID 32713969 DOI: 10.1016/J.Tet.2019.130819 |
0.743 |
|
| 2020 |
Babbs A, Berg A, Chatzopoulou M, Davies KE, Davies SG, Edwards B, Elsey D, Emer E, Guiraud S, Harriman S, Lecci C, Moir L, Peters D, Robinson N, Rowley J, ... Russell AJ, et al. 2-Arylbenzo[d]oxazole phosphinate esters as second-generation modulators of utrophin for the treatment of Duchenne Muscular Dystrophy. Journal of Medicinal Chemistry. PMID 32551645 DOI: 10.1021/Acs.Jmedchem.0C00807 |
0.737 |
|
| 2020 |
Storm T, Wilson I, Campbell R, Bolinches-Amorós A, Russell AJ, Davies SG, Barnard AR, MacLaren RE. A Semiautomated, Phenotypic, Scratch Assay for Assessing Retinal Pigment Epithelial Cell Wound Healing. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 32027217 DOI: 10.1089/Jop.2019.0116 |
0.42 |
|
| 2020 |
Babbs A, Berg A, Chatzopoulou M, Davies KE, Davies SG, Edwards B, Elsey DJ, Emer E, Figuccia AL, Fletcher AM, Guiraud S, Harriman S, Moir L, Robinson N, Rowley JA, ... Russell AJ, et al. Synthesis of SMT022357 enantiomers and in vivo evaluation in a Duchenne muscular dystrophy mouse model Tetrahedron. 76: 130819. DOI: 10.1016/j.tet.2019.130819 |
0.735 |
|
| 2019 |
Wilkinson IVL, Perkins KJ, Dugdale H, Moir L, Vuorinen A, Chatzopoulou M, Squire SE, Monecke S, Lomow A, Geese M, Charles PD, Burch P, Tinsley JM, Wynne GM, Davies SG, ... ... Russell AJ, et al. Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid. Angewandte Chemie (International Ed. in English). PMID 31755636 DOI: 10.1002/Anie.201912392 |
0.449 |
|
| 2019 |
Chatzopoulou M, Claridge TDW, Davies KE, Davies SG, Elsey D, Emer E, Fletcher AM, Harriman S, Robinson N, Rowley J, Russell AJ, Tinsley J, Weaver R, Wilkinson I, Willis N, et al. Isolation, structural identification, synthesis, and pharmacological profiling of 1,2-trans-dihydro-1,2-diol metabolites of the utrophin modulator ezutromid. Journal of Medicinal Chemistry. PMID 31599580 DOI: 10.1021/Acs.Jmedchem.9B01547 |
0.757 |
|
| 2018 |
Chatzopoulou M, Martínez RF, Willis NJ, Claridge TD, Wilson FX, Wynne GM, Davies SG, Russell AJ. The Dimroth rearrangement as a probable cause for structural misassignments in imidazo[1,2-a]pyrimidines: A N-labelling study and an easy method for the determination of regiochemistry Tetrahedron. 74: 5280-5288. DOI: 10.1016/J.Tet.2018.06.033 |
0.585 |
|
| 2017 |
Brambilla M, Brennan MB, Csatayová K, Davies SG, Fletcher AM, Kennett AMR, Lee JA, Roberts PM, Russell AJ, Thomson JE. Probing Competitive and Co-operative Hydroxyl and Ammonium Hydrogen-Bonding Directed Epoxidations. The Journal of Organic Chemistry. PMID 28858526 DOI: 10.1021/Acs.Joc.7B01774 |
0.561 |
|
| 2017 |
Bataille CJ, Brennan MB, Byrne S, Davies SG, Durbin M, Fedorov O, Huber KV, Jones AM, Knapp S, Liu G, Nadali A, Quevedo CE, Russell AJ, Walker RG, Westwood R, et al. Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family. Bioorganic & Medicinal Chemistry. PMID 28341403 DOI: 10.1016/J.Bmc.2017.02.056 |
0.546 |
|
| 2017 |
Wynne G, Vuorinen A, Emer E, Conole D, Chatzopoulou M, Davies S, Russell A, Guiraud S, Squire S, Berg A, Edwards B, Hemming S, Kennedy T, Moir L, Davies K, et al. Discovery of small molecule utrophin modulators for the therapy of Duchenne muscular dystrophy Neuromuscular Disorders. 27. DOI: 10.1016/J.Nmd.2017.06.348 |
0.676 |
|
| 2016 |
Davies SG, Goddard EC, Roberts PM, Russell AJ, Smith AD, Thomson JE, Withey JM. Strategies for the construction of morphinan alkaloid AB-rings: Regioselective Friedel-Crafts-type cyclisations of γ-aryl-β-benzoylamido acids with asymmetrically substituted γ-aryl rings Tetrahedron Asymmetry. DOI: 10.1016/J.Tetasy.2016.02.010 |
0.65 |
|
| 2015 |
Brennan MB, Csatayová K, Davies SG, Fletcher AM, Green WD, Lee JA, Roberts PM, Russell AJ, Thomson JE. Syntheses of Dihydroconduramines (±)-B-1, (±)-E-1, and (±)-F-1 via Diastereoselective Epoxidation of N-Protected 4-Aminocyclohex-2-en-1-ols. The Journal of Organic Chemistry. 80: 6609-18. PMID 25942585 DOI: 10.1021/Acs.Joc.5B00716 |
0.569 |
|
| 2015 |
Guiraud S, Squire SE, Edwards B, Chen H, Burns DT, Shah N, Babbs A, Davies SG, Wynne GM, Russell AJ, Elsey D, Wilson FX, Tinsley JM, Davies KE. Second-generation compound for the modulation of utrophin in the therapy of DMD. Human Molecular Genetics. 24: 4212-24. PMID 25935002 DOI: 10.1093/Hmg/Ddv154 |
0.544 |
|
| 2015 |
Davies SG, Kennewell PD, Russell AJ, Seden PT, Westwood R, Wynne GM. Stemistry: the control of stem cells in situ using chemistry. Journal of Medicinal Chemistry. 58: 2863-94. PMID 25590360 DOI: 10.1021/Jm500838D |
0.532 |
|
| 2015 |
Brennan MB, Davies SG, Fletcher AM, Lee JA, Roberts PM, Russell AJ, Thomson JE. Epoxidation of trans-4-aminocyclohex-2-en-1-ol derivatives: Competition of hydroxy-directed and ammonium-directed pathways Australian Journal of Chemistry. 68: 610-621. DOI: 10.1071/Ch14531 |
0.576 |
|
| 2015 |
Davies SG, Goddard EC, Roberts PM, Russell AJ, Thomson JE. Enantiopure 3-Amino-Substituted 1-Indanones, 1-Tetralones, and 1-Benzosuberones via Friedel-Crafts Cyclisation of ω-Aryl-β-benzamido Acids Synlett. 26: 1541-1544. DOI: 10.1055/S-0034-1380675 |
0.613 |
|
| 2014 |
Abuhammad A, Fullam E, Bhakta S, Russell AJ, Morris GM, Finn PW, Sim E. Exploration of piperidinols as potential antitubercular agents. Molecules (Basel, Switzerland). 19: 16274-90. PMID 25310152 DOI: 10.3390/Molecules191016274 |
0.335 |
|
| 2014 |
Laurieri N, Dairou J, Egleton JE, Stanley LA, Russell AJ, Dupret JM, Sim E, Rodrigues-Lima F. From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2. Plos One. 9: e96370. PMID 24823794 DOI: 10.1371/Journal.Pone.0096370 |
0.34 |
|
| 2014 |
Egleton JE, Thinnes CC, Seden PT, Laurieri N, Lee SP, Hadavizadeh KS, Measures AR, Jones AM, Thompson S, Varney A, Wynne GM, Ryan A, Sim E, Russell AJ. Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1. Bioorganic & Medicinal Chemistry. 22: 3030-54. PMID 24758871 DOI: 10.1016/J.Bmc.2014.03.015 |
0.54 |
|
| 2014 |
Fairclough R, Squire S, Araujo N, Vuorinen A, Davies S, Wynne G, Russell A, Davies K. P13 New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD) Neuromuscular Disorders. 24: S10. DOI: 10.1016/S0960-8966(14)70029-X |
0.471 |
|
| 2014 |
Fairclough R, Guiraud S, Squire S, Babbs A, Edward B, Shah N, Bracchi A, Wilson F, Horne G, Robinson N, Araujo N, Hewings D, Vuorinen A, Davies S, Wynne G, ... Russell A, et al. G.P.89 Neuromuscular Disorders. 24: 821. DOI: 10.1016/J.Nmd.2014.06.103 |
0.468 |
|
| 2013 |
Laurieri N, Egleton JE, Varney A, Thinnes CC, Quevedo CE, Seden PT, Thompson S, Rodrigues-Lima F, Dairou J, Dupret JM, Russell AJ, Sim E. A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1. Plos One. 8: e70600. PMID 23940600 DOI: 10.1371/Journal.Pone.0070600 |
0.518 |
|
| 2013 |
Fullam E, Talbot J, Abuhammed A, Westwood I, Davies SG, Russell AJ, Sim E. Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase. Bioorganic & Medicinal Chemistry Letters. 23: 2759-64. PMID 23518278 DOI: 10.1016/J.Bmcl.2013.02.052 |
0.583 |
|
| 2013 |
Hewings DS, Fedorov O, Filippakopoulos P, Martin S, Picaud S, Tumber A, Wells C, Olcina MM, Freeman K, Gill A, Ritchie AJ, Sheppard DW, Russell AJ, Hammond EM, Knapp S, et al. Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. Journal of Medicinal Chemistry. 56: 3217-27. PMID 23517011 DOI: 10.1021/Jm301588R |
0.319 |
|
| 2013 |
Claridge TDW, Davies SG, Kruchinin D, Odell B, Roberts PM, Russell AJ, Thomson JE, Toms SM. Solution phase structures of enantiopure and racemic lithium N-benzyl-N-(α-methylbenzyl)amide in THF: Low temperature 6Li and 15N NMR spectroscopic studies Tetrahedron Asymmetry. 24: 947-952. DOI: 10.1016/J.Tetasy.2013.07.001 |
0.611 |
|
| 2012 |
Abuhammad A, Fullam E, Lowe ED, Staunton D, Kawamura A, Westwood IM, Bhakta S, Garner AC, Wilson DL, Seden PT, Davies SG, Russell AJ, Garman EF, Sim E. Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages. Plos One. 7: e52790. PMID 23285185 DOI: 10.1371/Journal.Pone.0052790 |
0.564 |
|
| 2012 |
Davies SG, Fletcher AM, Lee JA, Roberts PM, Russell AJ, Taylor RJ, Thomson AD, Thomson JE. Polysubstituted piperidines via iodolactonization: application to the asymmetric synthesis of (+)-pseudodistomin D. Organic Letters. 14: 1672-5. PMID 22416848 DOI: 10.1021/Ol300209S |
0.599 |
|
| 2012 |
Fairclough R, Squire S, Potter A, Powell D, Davies S, Bataille C, Wynne G, Russell A, Davies K. O01 Identification of new chemical compounds with upregulate utrophin for the therapy of Duchenne muscular dystrophy Neuromuscular Disorders. 22: S3. DOI: 10.1016/S0960-8966(12)00071-5 |
0.424 |
|
| 2011 |
Csatayová K, Davies SG, Lee JA, Roberts PM, Russell AJ, Thomson JE, Wilson DL. Highly diastereoselective and stereodivergent dihydroxylations of acyclic allylic amines: application to the asymmetric synthesis of 3,6-dideoxy-3-amino-L-talose. Organic Letters. 13: 2606-9. PMID 21488631 DOI: 10.1021/Ol200717N |
0.57 |
|
| 2011 |
Fullam E, Abuhammad A, Wilson DL, Anderton MC, Davies SG, Russell AJ, Sim E. Analysis of β-amino alcohols as inhibitors of the potential anti-tubercular target N-acetyltransferase. Bioorganic & Medicinal Chemistry Letters. 21: 1185-90. PMID 21251821 DOI: 10.1016/J.Bmcl.2010.12.099 |
0.589 |
|
| 2011 |
Westwood IM, Kawamura A, Russell AJ, Sandy J, Davies SG, Sim E. Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening. Combinatorial Chemistry & High Throughput Screening. 14: 117-24. PMID 21118080 DOI: 10.2174/138620711794474051 |
0.559 |
|
| 2011 |
Abuhammad A, Fullam E, Westwood I, Russell A, Davies S, Sim E. Structural studies on novel antitubercular targets Acta Crystallographica Section a Foundations of Crystallography. 67: C289-C290. DOI: 10.1107/S0108767311092762 |
0.462 |
|
| 2011 |
Fairclough R, Powell D, Squire S, Potter A, Bareja A, Russell A, Davies S, Davies K. P05 Utrophin upregulation in DMD therapy: current status and new tools for the future Neuromuscular Disorders. 21: S8. DOI: 10.1016/S0960-8966(11)70024-4 |
0.383 |
|
| 2011 |
Abraham E, Claridge TDW, Davies SG, Odell B, Roberts PM, Russell AJ, Smith AD, Smith LJ, Storr HR, Sweet MJ, Thompson AL, Thomson JE, Tranter GE, Watkin DJ. A systematic study of the solid state and solution phase conformational preferences of β-peptides derived from C(3)-alkyl substituted transpentacin derivatives Tetrahedron Asymmetry. 22: 69-100. DOI: 10.1016/J.Tetasy.2010.12.007 |
0.627 |
|
| 2011 |
Davies SG, Fletcher AM, Hughes DG, Lee JA, Price PD, Roberts PM, Russell AJ, Smith AD, Thomson JE, Williams OMH. Asymmetric synthesis of piperidines and octahydroindolizines using a one-pot ring-closure/N-debenzylation procedure Tetrahedron. 67: 9975-9992. DOI: 10.1016/J.Tet.2011.09.038 |
0.649 |
|
| 2010 |
Westwood IM, Bhakta S, Russell AJ, Fullam E, Anderton MC, Kawamura A, Mulvaney AW, Vickers RJ, Bhowruth V, Besra GS, Lalvani A, Davies SG, Sim E. Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars. Protein & Cell. 1: 82-95. PMID 21204000 DOI: 10.1007/S13238-010-0006-1 |
0.563 |
|
| 2010 |
Csatayová K, Davies SG, Lee JA, Ling KB, Roberts PM, Russell AJ, Thomson JE. Syntheses of trans-SCH-A and cis-SCH-A via a stereodivergent cyclopropanation protocol. Organic Letters. 12: 3152-5. PMID 20552964 DOI: 10.1021/Ol101295T |
0.547 |
|
| 2010 |
Cresswell AJ, Davies SG, Lee JA, Roberts PM, Russell AJ, Thomson JE, Tyte MJ. Beta-fluoroamphetamines via the stereoselective synthesis of benzylic fluorides. Organic Letters. 12: 2936-9. PMID 20509635 DOI: 10.1021/Ol100862S |
0.775 |
|
| 2010 |
Laurieri N, Crawford MH, Kawamura A, Westwood IM, Robinson J, Fletcher AM, Davies SG, Sim E, Russell AJ. Small molecule colorimetric probes for specific detection of human arylamine N-acetyltransferase 1, a potential breast cancer biomarker. Journal of the American Chemical Society. 132: 3238-9. PMID 20170182 DOI: 10.1021/Ja909165U |
0.571 |
|
| 2010 |
Bagal SK, Davies SG, Lee JA, Roberts PM, Russell AJ, Scott PM, Thomson JE. An oxidation and ring contraction approach to the synthesis of (+/-)-1-deoxynojirimycin and (+/-)-1-deoxyaltronojirimycin. Organic Letters. 12: 136-9. PMID 19954199 DOI: 10.1021/Ol902533B |
0.604 |
|
| 2010 |
Davies S, Csatayová K, Lee J, Ling K, Roberts P, Russell A, Thomson J. Synthesis oftrans-SCH-A Synfacts. 2010: 1096-1096. DOI: 10.1055/s-0030-1258077 |
0.508 |
|
| 2010 |
Davies SG, Hughes DG, Price PD, Roberts PM, Russell AJ, Smith AD, Thomson JE, Williams OMH. Asymmetric synthesis of piperidines and octahydroindolizines Synlett. 567-570. DOI: 10.1055/S-0029-1219346 |
0.659 |
|
| 2010 |
Abraham E, Bailey CW, Claridge TDW, Davies SG, Ling KB, Odell B, Rees TL, Roberts PM, Russell AJ, Smith AD, Smith LJ, Storr HR, Sweet MJ, Thompson AL, Thomson JE, et al. A systematic study of the solid state and solution phase conformational preferences of β-peptides derived from transpentacin Tetrahedron Asymmetry. 21: 1797-1815. DOI: 10.1016/J.Tetasy.2010.06.001 |
0.588 |
|
| 2010 |
Csatayová K, Davies SG, Lee JA, Ling KB, Roberts PM, Russell AJ, Thomson JE. Chemo- and diastereoselective cyclopropanation of allylic amines and carbamates Tetrahedron. 66: 8420-8440. DOI: 10.1016/J.Tet.2010.08.055 |
0.571 |
|
| 2010 |
Davies SG, Ling KB, Roberts PM, Russell AJ, Thomson JE, Woods PA. The stereodivergent aziridination of allylic carbamates, amides and sulfonamides Tetrahedron. 66: 6806-6813. DOI: 10.1016/J.Tet.2010.06.059 |
0.572 |
|
| 2010 |
Bentley SA, Davies SG, Lee JA, Roberts PM, Russell AJ, Thomson JE, Toms SM. Conjugate addition of lithium N-tert-butyldimethylsilyloxy-N-(α-methylbenzyl)amide: asymmetric synthesis of β2,2,3-trisubstituted amino acids Tetrahedron. 66: 4604-4620. DOI: 10.1016/J.Tet.2010.04.027 |
0.62 |
|
| 2010 |
Bentley SA, Davies SG, Lee JA, Roberts PM, Russell AJ, Thomson JE, Toms SM. ChemInform Abstract: Conjugate Addition of Lithium N-tert-Butyldimethylsilyloxy-N-(α-methylbenzyl)amide: Asymmetric Synthesis of β2,2,3-Trisubstituted Amino Acids. Cheminform. 41: no-no. DOI: 10.1002/CHIN.201043070 |
0.452 |
|
| 2009 |
Bond CW, Cresswell AJ, Davies SG, Fletcher AM, Kurosawa W, Lee JA, Roberts PM, Russell AJ, Smith AD, Thomson JE. Ammonium-directed oxidation of cyclic allylic and homoallylic amines. The Journal of Organic Chemistry. 74: 6735-48. PMID 19642691 DOI: 10.5059/Yukigoseikyokaishi.68.1295 |
0.788 |
|
| 2009 |
Soncin F, Mohamet L, Eckardt D, Ritson S, Eastham AM, Bobola N, Russell A, Davies S, Kemler R, Merry CL, Ward CM. Abrogation of E-cadherin-mediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal. Stem Cells (Dayton, Ohio). 27: 2069-80. PMID 19544408 DOI: 10.1002/Stem.134 |
0.426 |
|
| 2009 |
Wilkinson RN, Pouget C, Gering M, Russell AJ, Davies SG, Kimelman D, Patient R. Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta. Developmental Cell. 16: 909-16. PMID 19531361 DOI: 10.1016/J.Devcel.2009.04.014 |
0.506 |
|
| 2009 |
Pettigrew DM, Roversi P, Davies SG, Russell AJ, Lea SM. A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol. Acta Crystallographica. Section D, Biological Crystallography. 65: 513-22. PMID 19465765 DOI: 10.1107/S0907444909005113 |
0.544 |
|
| 2009 |
Aciro C, Davies SG, Kurosawa W, Roberts PM, Russell AJ, Thomson JE. Highly diastereoselective anti-dihydroxylation of 3-N,N-dibenzylaminocyclohex-1-ene N-oxide. Organic Letters. 11: 1333-6. PMID 19209907 DOI: 10.1021/Ol900114B |
0.577 |
|
| 2009 |
Davies SG, Durbin MJ, Goddard EC, Kelly PM, Kurosawa W, Lee JA, Nicholson RL, Price PD, Roberts PM, Russell AJ, Scott PM, Smith AD. Doubly diastereoselective conjugate addition of homochiral lithium amides to homochiral alpha,beta-unsaturated esters containing cis- and trans-dioxolane units. Organic & Biomolecular Chemistry. 7: 761-76. PMID 19194592 DOI: 10.1039/B818298A |
0.624 |
|
| 2009 |
Kachoosangi RT, Musameh MM, Abu-Yousef I, Yousef JM, Kanan SM, Xiao L, Davies SG, Russell A, Compton RG. Carbon nanotube-ionic liquid composite sensors and biosensors. Analytical Chemistry. 81: 435-42. PMID 19117466 DOI: 10.1021/Ac801853R |
0.501 |
|
| 2009 |
Russell AJ, Westwood IM, Crawford MH, Robinson J, Kawamura A, Redfield C, Laurieri N, Lowe ED, Davies SG, Sim E. Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2. Bioorganic & Medicinal Chemistry. 17: 905-18. PMID 19059786 DOI: 10.1016/J.Bmc.2008.11.032 |
0.587 |
|
| 2009 |
Davies SG, Nicholson RL, Price PD, Roberts PM, Russell AJ, Savory ED, Smith AD, Thomson JE. Iodine-mediated ring-closing iodoamination with concomitant N-debenzylation for the asymmetric synthesis of polyhydroxylated pyrrolidines Tetrahedron Asymmetry. 20: 758-772. DOI: 10.1016/J.Tetasy.2009.02.014 |
0.666 |
|
| 2008 |
Claridge TD, Davies SG, Lee JA, Nicholson RL, Roberts PM, Russell AJ, Smith AD, Toms SM. Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide. Organic Letters. 10: 5437-40. PMID 18975957 DOI: 10.1021/Ol802212E |
0.602 |
|
| 2008 |
Claridge TD, Davies SG, Polywka ME, Roberts PM, Russell AJ, Savory ED, Smith AD. "Pure by NMR"? Organic Letters. 10: 5433-6. PMID 18975956 DOI: 10.1021/Ol802211P |
0.568 |
|
| 2008 |
Aciro C, Davies SG, Roberts PM, Russell AJ, Smith AD, Thomson JE. Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol. Organic & Biomolecular Chemistry. 6: 3762-70. PMID 18843406 DOI: 10.1039/B808812H |
0.633 |
|
| 2008 |
Aciro C, Claridge TD, Davies SG, Roberts PM, Russell AJ, Thomson JE. Ammonium-directed dihydroxylation of 3-aminocyclohex-1-enes: development of a metal-free dihydroxylation protocol. Organic & Biomolecular Chemistry. 6: 3751-61. PMID 18843405 DOI: 10.1039/B808811J |
0.569 |
|
| 2008 |
Abraham E, Brock EA, Candela-Lena JI, Davies SG, Georgiou M, Nicholson RL, Perkins JH, Roberts PM, Russell AJ, Sánchez-Fernández EM, Scott PM, Smith AD, Thomson JE. Asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition. Organic & Biomolecular Chemistry. 6: 1665-73. PMID 18421401 DOI: 10.1039/B801671B |
0.624 |
|
| 2008 |
Davies SG, Mortimer DA, Mulvaney AW, Russell AJ, Skarphedinsson H, Smith AD, Vickers RJ. An oxidatively-activated safety catch linker for solid phase synthesis. Organic & Biomolecular Chemistry. 6: 1625-34. PMID 18421396 DOI: 10.1039/B802204F |
0.627 |
|
| 2008 |
Davies SG, Durbin MJ, Hartman SJS, Matsuno A, Roberts PM, Russell AJ, Smith AD, Thomson JE, Toms SM. Parallel kinetic resolution of tert-butyl (RS)-6-alkyl-cyclohex-1-ene-carboxylates for the asymmetric synthesis of 6-alkyl-substituted cishexacin derivatives Tetrahedron Asymmetry. 19: 2870-2881. DOI: 10.1016/J.Tetasy.2008.11.019 |
0.656 |
|
| 2008 |
Case-Green SC, Davies SG, Roberts PM, Russell AJ, Thomson JE. Asymmetric synthesis of tetrahydrolipstatin and valilactone Tetrahedron Asymmetry. 19: 2620-2631. DOI: 10.1016/J.Tetasy.2008.11.012 |
0.566 |
|
| 2008 |
Abraham E, Davies SG, Docherty AJ, Ling KB, Roberts PM, Russell AJ, Thomson JE, Toms SM. Parallel kinetic resolution of methyl (RS)-5-tris(phenylthio)methyl-cyclopent-1-ene-carboxylate for the asymmetric synthesis of (1R,2S,5S)- and (1S,2R,5R)-5-methyl-cispentacin Tetrahedron Asymmetry. 19: 1356-1362. DOI: 10.1016/J.Tetasy.2008.05.016 |
0.561 |
|
| 2008 |
Abraham E, Davies SG, Roberts PM, Russell AJ, Thomson JE. Jaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignment Tetrahedron Asymmetry. 19: 1027-1047. DOI: 10.1016/J.Tetasy.2008.04.017 |
0.517 |
|
| 2008 |
Aciro C, Davies SG, Garner AC, Ishii Y, Key MS, Ling KB, Prasad RS, Roberts PM, Rodriguez-Solla H, O'Leary-Steele C, Russell AJ, Sanganee HJ, Savory ED, Smith AD, Thomson JE. Stereoselective functionalisation of SuperQuat enamides: asymmetric synthesis of homochiral 1,2-diols and α-benzyloxy carbonyl compounds Tetrahedron. 64: 9320-9344. DOI: 10.1016/J.Tet.2008.07.012 |
0.663 |
|
| 2008 |
Davies SG, Russell AJ, Sheppard RL, Smith AD, Thomson JE. ChemInform Abstract: Evaluating β-Amino Acids as Enantioselective Organocatalysts of the Hajos—Parrish—Eder—Sauer—Wiechert Reaction. Cheminform. 39. DOI: 10.1002/chin.200806095 |
0.515 |
|
| 2008 |
Beddow JE, Davies SG, Ling KB, Roberts PM, Russell AJ, Smith AD, Thomson JE. ChemInform Abstract: Asymmetric Synthesis of β2-Amino Acids: 2-Substituted-3-aminopropanoic Acids from N-Acryloyl SuperQuat Derivatives. Cheminform. 39. DOI: 10.1002/CHIN.200801183 |
0.432 |
|
| 2007 |
Cailleau T, Cooke JW, Davies SG, Ling KB, Naylor A, Nicholson RL, Price PD, Roberts PM, Russell AJ, Smith AD, Thomson JE. Asymmetric synthesis of beta-amino-gamma-substituted-gamma-butyrolactones: double diastereoselective conjugate addition of homochiral lithium amides to homochiral alpha,beta-unsaturated esters. Organic & Biomolecular Chemistry. 5: 3922-31. PMID 18043795 DOI: 10.1039/B712937H |
0.617 |
|
| 2007 |
Davies SG, Ling KB, Roberts PM, Russell AJ, Thomson JE. Diastereoselective Simmons-Smith cyclopropanations of allylic amines and carbamates. Chemical Communications (Cambridge, England). 4029-31. PMID 17912405 DOI: 10.1039/B711358G |
0.589 |
|
| 2007 |
Davies SG, Russell AJ, Sheppard RL, Smith AD, Thomson JE. Evaluating beta-amino acids as enantioselective organocatalysts of the Hajos-Parrish-Eder-Sauer-Wiechert reaction. Organic & Biomolecular Chemistry. 5: 3190-200. PMID 17878978 DOI: 10.1039/B711171A |
0.605 |
|
| 2007 |
Beddow JE, Davies SG, Ling KB, Roberts PM, Russell AJ, Smith AD, Thomson JE. Asymmetric synthesis of beta2-amino acids: 2-substituted-3-aminopropanoic acids from N-acryloyl SuperQuat derivatives. Organic & Biomolecular Chemistry. 5: 2812-25. PMID 17700850 DOI: 10.1039/B707689D |
0.653 |
|
| 2007 |
Madikane VE, Bhakta S, Russell AJ, Campbell WE, Claridge TD, Elisha BG, Davies SG, Smith P, Sim E. Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris. Bioorganic & Medicinal Chemistry. 15: 3579-86. PMID 17368035 DOI: 10.1016/J.Bmc.2007.02.011 |
0.56 |
|
| 2007 |
Rogers EI, Silvester DS, Jones SEW, Aldous L, Hardacre C, Russell AJ, Davies SG, Compton RG. Electrochemical kinetics of Ag|Ag+ and TMPD|TMPD+ in the room-temperature ionic liquid [C4mpyrr][NTf2]; toward optimizing reference electrodes for voltammetry in RTILs Journal of Physical Chemistry C. 111: 13957-13966. DOI: 10.1021/Jp0737754 |
0.513 |
|
| 2007 |
Abraham E, Candela-Lena JI, Davies SG, Georgiou M, Nicholson RL, Roberts PM, Russell AJ, Sánchez-Fernández EM, Smith AD, Thomson JE. Asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine, jaspine B (pachastrissamine) and its C(2)-epimer Tetrahedron Asymmetry. 18: 2510-2513. DOI: 10.1016/J.Tetasy.2007.10.026 |
0.623 |
|
| 2007 |
Davies SG, Mulvaney AW, Russell AJ, Smith AD. Parallel synthesis of homochiral β-amino acids Tetrahedron Asymmetry. 18: 1554-1566. DOI: 10.1016/J.Tetasy.2007.06.008 |
0.651 |
|
| 2006 |
Westwood IM, Kawamura A, Fullam E, Russell AJ, Davies SG, Sim E. Structure and mechanism of arylamine N-acetyltransferases. Current Topics in Medicinal Chemistry. 6: 1641-54. PMID 16918475 DOI: 10.2174/156802606778108979 |
0.549 |
|
| 2006 |
Davies SG, Garrido NM, Kruchinin D, Ichihara O, Kotchie LJ, Price PD, Mortimer AJP, Russell AJ, Smith AD. Homochiral lithium amides for the asymmetric synthesis of β-amino acids Tetrahedron Asymmetry. 17: 1793-1811. DOI: 10.1016/J.Tetasy.2006.05.008 |
0.621 |
|
| 2006 |
Candela-Lena JI, Davies SG, Roberts PM, Roux B, Russell AJ, Sánchez-Fernández EM, Smith AD. Asymmetric synthesis of α-mercapto-β-amino acid derivatives: application to the synthesis of polysubstituted thiomorpholines Tetrahedron: Asymmetry. 17: 1135-1145. DOI: 10.1016/J.Tetasy.2006.04.004 |
0.654 |
|
| 2006 |
Davies SG, Garrido NM, Kruchinin D, Ichihara O, Kotchie LJ, Price PD, Mortimer AJP, Russell AJ, Smith AD. Homochiral Lithium Amides for the Asymmetric Synthesis of β-Amino Acids. Cheminform. 37. DOI: 10.1002/chin.200651059 |
0.527 |
|
| 2004 |
Beddow JE, Davies SG, Smith AD, Russell AJ. Asymmetric synthesis of 2-alkyl- and 2-aryl-3-aminopropionic acids (beta2-amino acids) from (S)-N-acryloyl-5,5-dimethyloxazolidin-2-one SuperQuat derivatives. Chemical Communications (Cambridge, England). 2778-9. PMID 15568113 DOI: 10.1039/B410938D |
0.659 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2018 |
Stefaniak J, Lewis AM, Conole D, Galan SRG, Bataille CJR, Wynne GM, Castaldi MP, Lundbäck T, Russell AJ, Huber KVM. Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-based MDMX Inhibitors. Acs Chemical Biology. PMID 30216042 DOI: 10.1021/Acschembio.8B00665 |
0.299 |
|
| 2019 |
Wilkinson IVL, Reynolds JK, Galan SRG, Vuorinen A, Sills AJ, Pires E, Wynne GM, Wilson FX, Russell AJ. Characterisation of utrophin modulator SMT C1100 as a non-competitive inhibitor of firefly luciferase. Bioorganic Chemistry. 103395. PMID 31733898 DOI: 10.1016/J.Bioorg.2019.103395 |
0.291 |
|
| 2014 |
Laurieri N, Kawamura A, Westwood IM, Varney A, Morris E, Russell AJ, Stanley LA, Sim E. Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding. Bmc Pharmacology & Toxicology. 15: 68. PMID 25432241 DOI: 10.1186/2050-6511-15-68 |
0.291 |
|
| 2017 |
Kerr AG, Tam LC, Hale AB, Cioroch M, Douglas G, Agkatsev S, Hibbit O, Mason J, Holt-Martyn J, Bataille CJ, Wynne GM, Channon KM, Russell AJ, Wade-Martins R. A genomic DNA reporter screen identifies squalene synthase inhibitors which act cooperatively with statins to upregulate the low-density lipoprotein receptor. The Journal of Pharmacology and Experimental Therapeutics. PMID 28360334 DOI: 10.1124/Jpet.116.239574 |
0.286 |
|
| 2017 |
Partridge FA, Murphy EA, Willis NJ, Bataille CJ, Forman R, Heyer-Chauhan N, Marinič B, Sowood DJ, Wynne GM, Else KJ, Russell AJ, Sattelle DB. Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo. Plos Neglected Tropical Diseases. 11: e0005359. PMID 28182663 DOI: 10.1371/Journal.Pntd.0005359 |
0.285 |
|
| 2009 |
Lack NA, Kawamura A, Fullam E, Laurieri N, Beard S, Russell AJ, Evangelopoulos D, Westwood I, Sim E. Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis. The Biochemical Journal. 418: 369-78. PMID 19014350 DOI: 10.1042/Bj20082011 |
0.282 |
|
| 2015 |
Clunie-O'Connor C, Smits AM, Antoniades C, Russell AJ, Yellon DM, Goumans MJ, Riley PR. The Derivation of Primary Human Epicardium-Derived Cells. Current Protocols in Stem Cell Biology. 35: 2C.5.1-2C.5.12. PMID 26544538 DOI: 10.1002/9780470151808.Sc02C05S35 |
0.279 |
|
| 2015 |
Gianella-Borradori M, Christou I, Bataille CJ, Cross RL, Wynne GM, Greaves DR, Russell AJ. Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists. Bioorganic & Medicinal Chemistry. 23: 241-63. PMID 25487422 DOI: 10.1016/J.Bmc.2014.11.002 |
0.266 |
|
| 2020 |
Partridge FA, Forman R, Bataille CJR, Wynne GM, Nick M, Russell AJ, Else KJ, Sattelle DB. Anthelmintic drug discovery: target identification, screening methods and the role of open science. Beilstein Journal of Organic Chemistry. 16: 1203-1224. PMID 32550933 DOI: 10.3762/Bjoc.16.105 |
0.265 |
|
| 2017 |
Partridge FA, Brown AE, Buckingham SD, Willis NJ, Wynne GM, Forman R, Else KJ, Morrison AA, Matthews JB, Russell AJ, Lomas DA, Sattelle DB. An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes. International Journal For Parasitology. Drugs and Drug Resistance. 8: 8-21. PMID 29223747 DOI: 10.1016/J.Ijpddr.2017.11.004 |
0.265 |
|
| 2019 |
Lucy D, Purvis GSD, Zeboudj L, Chatzopoulou M, Recio C, Bataille CJR, Wynne GM, Greaves DR, Russell AJ. A biased agonist at immunometabolic receptor GPR84 causes distinct functional effects in macrophages. Acs Chemical Biology. PMID 31465201 DOI: 10.1021/Acschembio.9B00533 |
0.264 |
|
| 2020 |
Hua P, Hester J, Adigbli G, Li R, Psaila B, Roy A, Bataille CJR, Wynne GM, Jackson T, Milne TA, Russell A, Davies J, Roberts I, Issa F, Watt SM. The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes. Blood. PMID 32599615 DOI: 10.1182/Blood.2020005357 |
0.264 |
|
| 2013 |
Lufino MM, Silva AM, Németh AH, Alegre-Abarrategui J, Russell AJ, Wade-Martins R. A GAA repeat expansion reporter model of Friedreich's ataxia recapitulates the genomic context and allows rapid screening of therapeutic compounds. Human Molecular Genetics. 22: 5173-87. PMID 23943791 DOI: 10.1093/Hmg/Ddt370 |
0.263 |
|
| 2019 |
Cruz-Migoni A, Canning P, Quevedo CE, Bataille CJR, Bery N, Miller A, Russell AJ, Phillips SEV, Carr SB, Rabbitts TH. Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds. Proceedings of the National Academy of Sciences of the United States of America. PMID 30683716 DOI: 10.2210/Pdb6Goe/Pdb |
0.262 |
|
| 2018 |
Partridge FA, Forman R, Willis NJ, Bataille CJR, Murphy EA, Brown AE, Heyer-Chauhan N, Marinič B, Sowood DJC, Wynne GM, Else KJ, Russell AJ, Sattelle DB. 2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm. Plos Neglected Tropical Diseases. 12: e0006487. PMID 29995893 DOI: 10.1371/Journal.Pntd.0006487 |
0.261 |
|
| 2013 |
McIntyre A, Hulikova A, Ledaki I, Seden P, Turley H, Jones D, Russell A, Swietach P, Harris AL. Abstract 4053: Hypoxic trans-activation of sodium dependent bicarbonate co-transporters regulates pH in 3D spheroids and promotes growth. Cancer Research. 73: 4053-4053. DOI: 10.1158/1538-7445.Am2013-4053 |
0.259 |
|
| 2013 |
Russell AJ. Regenerative medicinal chemistry: the in situ control of stem cells. Acs Medicinal Chemistry Letters. 4: 365-8. PMID 24900675 DOI: 10.1021/Ml400110B |
0.255 |
|
| 2018 |
Quevedo CE, Cruz-Migoni A, Bery N, Miller A, Tanaka T, Petch D, Bataille CJR, Lee LYW, Fallon PS, Tulmin H, Ehebauer MT, Fernandez-Fuentes N, Russell AJ, Carr SB, Phillips SEV, et al. Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment. Nature Communications. 9: 3169. PMID 30093669 DOI: 10.1038/S41467-018-05707-2 |
0.254 |
|
| 2016 |
Kerr AG, Tam L, Cioroch M, Hale A, Douglas G, Mason J, Bataille C, Wynne G, Russell A, Channon K, Wade-Martins R. 19. Using a Novel Combinatorial Non-Viral Vector and Small Molecules to Treat Familial Hypercholesterolaemia (FH) Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32828-3 |
0.247 |
|
| 2015 |
Araujo N, Vuorinen A, Fairclough R, Guiraud S, Donald J, Cairnduff C, Hewings D, Martinez F, Csatayova K, Willis N, Squire S, Babbs A, Edwards B, Shah N, Tinsley J, ... ... Russell A, et al. Discovery of small molecule utrophin modulators for the therapy of Duchenne muscular dystrophy (DMD) Neuromuscular Disorders. 25: S260. DOI: 10.1016/J.Nmd.2015.06.272 |
0.244 |
|
| 2020 |
Babbs A, Chatzopoulou M, Edwards B, Squire SE, Wilkinson IVL, Wynne GM, Russell AJ, Davies KE. From diagnosis to therapy in Duchenne muscular dystrophy. Biochemical Society Transactions. PMID 32597486 DOI: 10.1042/Bst20190282 |
0.243 |
|
| 2020 |
Kennedy TL, Russell AJ, Riley P. Experimental Limitations of Extracellular Vesicle-Based Therapies for the Treatment of Myocardial Infarction. Trends in Cardiovascular Medicine. PMID 32822840 DOI: 10.1016/J.Tcm.2020.08.003 |
0.241 |
|
| 2017 |
Quevedo CE, Cruz A, Tulmin H, Bataille CJ, Tanaka T, Petch D, Russell AJ, Phillips S, Rabbitts TH. Abstract LB-068: From intracellular antibody fragments to small molecule inhibitors of mutant KRAS Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-068 |
0.237 |
|
| 2012 |
Williams JG, Manzano A, Bensaad K, Collins JM, Serres S, CT, Sibson N, Bartrons R, Russell AJ, Harris AL. Isoenzyme-specific PFK-2/FBPase-2 Inhibition as an Anti-cancer Strategy European Journal of Cancer. 48. DOI: 10.1016/S0959-8049(12)70886-9 |
0.235 |
|
| 2017 |
Recio C, Lucy D, Iveson P, Iqbal AJ, Valaris S, Wynne G, Russell AJ, Choudhury R, O'Callaghan C, Monaco C, Greaves DR. The Role of Metabolite-sensing G Protein-Coupled Receptors in inflammation and metabolic disease. Antioxidants & Redox Signaling. PMID 29117706 DOI: 10.1089/Ars.2017.7168 |
0.235 |
|
| 2015 |
Taylor L, Christou I, Kapellos TS, Buchan A, Brodermann MH, Gianella-Borradori M, Russell A, Iqbal AJ, Greaves DR. Primary Macrophage Chemotaxis Induced by Cannabinoid Receptor 2 Agonists Occurs Independently of the CB2 Receptor. Scientific Reports. 5: 10682. PMID 26033291 DOI: 10.1038/Srep10682 |
0.234 |
|
| 2018 |
Recio C, Lucy D, Purvis GSD, Iveson P, Zeboudj L, Iqbal AJ, Lin D, O'Callaghan C, Davison L, Griesbach E, Russell AJ, Wynne GM, Dib L, Monaco C, Greaves DR. Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages. Frontiers in Immunology. 9: 1419. PMID 29973940 DOI: 10.3389/Fimmu.2018.01419 |
0.234 |
|
| 2015 |
Guiraud S, Chen H, Squire S, Edwards B, Burns D, Shah N, Davies S, Wynne G, Russell A, Elsey D, Wilson F, Tinsley J, Davies K. Utrophin modulators significantly improve muscular dystrophy in the mdx diaphragm Neuromuscular Disorders. 25: S260. DOI: 10.1016/J.Nmd.2015.06.271 |
0.234 |
|
| 2015 |
Guiraud S, Squire S, Edwards B, Chen H, Burns D, Shah N, Babbs A, Davies S, Wynne G, Russell A, Elsey D, Wilson F, Tinsley J, Davies K. Second generation utrophin modulator for the therapy of Duchenne muscular dystrophy Neuromuscular Disorders. 25. DOI: 10.1016/J.Nmd.2015.06.270 |
0.232 |
|
| 2016 |
McIntyre A, Hulikova A, Ledaki I, Snell C, Singleton D, Steers G, Seden P, Jones D, Bridges E, Wigfield S, Li JL, Russell A, Swietach P, Harris AL. Disrupting hypoxia-induced bicarbonate transport acidifies tumor cells and suppresses tumor growth. Cancer Research. PMID 27197160 DOI: 10.1158/0008-5472.Can-15-1862 |
0.228 |
|
| 2015 |
Zervou S, Whittington HJ, Russell AJ, Lygate CA. Augmentation of Creatine in the Heart. Mini Reviews in Medicinal Chemistry. 16: 19-28. PMID 26202199 DOI: 10.2174/1389557515666150722102151 |
0.227 |
|
| 2017 |
Venturi E, Lindsay C, Lotteau S, Yang Z, Steer E, Witschas K, Wilson AD, Wickens JR, Russell AJ, Steele D, Calaghan S, Sitsapesan R. Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform. British Journal of Pharmacology. PMID 29278865 DOI: 10.1111/Bph.14136 |
0.226 |
|
| 2017 |
Muntoni F, Maresh K, Davies K, Harriman S, Layton G, Rosskamp R, Russell A, Tejura B, Tinsley J. PhaseOut DMD: a Phase 2, proof of concept, clinical study of utrophin modulation with ezutromid Neuromuscular Disorders. 27. DOI: 10.1016/J.Nmd.2017.06.443 |
0.224 |
|
| 2016 |
Russell AJ, Silpa L. Chemical-Induced Naive Pluripotency. Cell Chemical Biology. 23: 532-4. PMID 27203371 DOI: 10.1016/J.Chembiol.2016.05.002 |
0.223 |
|
| 2011 |
Li JL, Sainson RC, Oon CE, Turley H, Leek R, Sheldon H, Bridges E, Shi W, Snell C, Bowden ET, Wu H, Chowdhury PS, Russell AJ, Montgomery CP, Poulsom R, et al. DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo. Cancer Research. 71: 6073-83. PMID 21803743 DOI: 10.1158/0008-5472.Can-11-1704 |
0.218 |
|
| 2018 |
Bery N, Cruz-Migoni A, Bataille CJ, Quevedo CE, Tulmin H, Miller A, Russell A, Phillips SE, Carr SB, Rabbitts TH. BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. Elife. 7. PMID 29989546 DOI: 10.7554/Elife.37122 |
0.218 |
|
| 2020 |
Dinsdale R, Russell A, Stansfeld PJ, Tammaro P. Molecular Mechanism of Modulation of the TMEM16A Channel by Anthracene-9-Carboxylic Acid: Implications for Channel Gating Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1823 |
0.217 |
|
| 2016 |
Burns D, Guiraud S, Carr C, Squire S, Edwards B, Chen H, Kennedy T, Babbs A, Shah N, Berg A, Wynne G, Russell A, Elsey D, Harriman S, Wilson F, et al. Utrophin modulation for the treatment of cardiomyopathy in mdx mice Neuromuscular Disorders. 26: S131. DOI: 10.1016/J.Nmd.2016.06.166 |
0.214 |
|
| 1995 |
Haley A, Russell AJ, Wood N, Allan AC, Knight M, Campbell AK, Trewavas AJ. Effects of mechanical signaling on plant cell cytosolic calcium. Proceedings of the National Academy of Sciences of the United States of America. 92: 4124-8. PMID 11536690 DOI: 10.1073/Pnas.92.10.4124 |
0.205 |
|
| 2018 |
Lindsay C, Wilson AD, Venturi E, Russell AJ, Sitsapesan R. Atorvastatin Activates Skeletal RyR1 Channels: Towards Reducing Statin Side-Effects Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.2589 |
0.203 |
|
| 2008 |
Musameh MM, Kachoosangi RT, Xiao L, Russell A, Compton RG. Ionic liquid-carbon composite glucose biosensor. Biosensors & Bioelectronics. 24: 87-92. PMID 18457943 DOI: 10.1016/J.Bios.2008.03.015 |
0.198 |
|
| 2018 |
Wilson AD, Lindsay C, Venturi E, Russell AJ, Sitsapesan R. Statins Bind to Cardiac Ryanodine Receptor (RyR2) Channels to Alter Opening Frequency Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.3361 |
0.185 |
|
| 2022 |
Chatzopoulou M, Madden KS, Bromhead LJ, Greaves C, Cogswell TJ, Da Silva Pinto S, Galan SRG, Georgiou I, Kennedy MS, Kennett A, Apps G, Russell AJ, Wynne GM. Pilot Study to Quantify Palladium Impurities in Lead-like Compounds Following Commonly Used Purification Techniques. Acs Medicinal Chemistry Letters. 13: 262-270. PMID 35173892 DOI: 10.1021/acsmedchemlett.1c00638 |
0.162 |
|
| 2023 |
Wang P, Raja A, Luscombe VB, Bataille CJR, Lucy D, Rogga VV, Greaves DR, Russell AJ. Development of Highly Potent, G-Protein Pathway Biased, Selective, and Orally Bioavailable GPR84 Agonists. Journal of Medicinal Chemistry. PMID 38146625 DOI: 10.1021/acs.jmedchem.3c00951 |
0.158 |
|
| 2021 |
Partridge FA, Bataille CJR, Forman R, Marriott AE, Forde-Thomas J, Häberli C, Dinsdale RL, O'Sullivan JDB, Willis NJ, Wynne GM, Whiteland H, Archer J, Steven A, Keiser J, Turner JD, ... ... Russell AJ, et al. Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: , , , and . Acs Infectious Diseases. PMID 33797218 DOI: 10.1021/acsinfecdis.1c00025 |
0.148 |
|
| 2022 |
Lindsay C, Musgaard M, Russell AJ, Sitsapesan R. Statin-activation of RyR1 is a class effect but separable from HMG-CoA reductase inhibition. British Journal of Pharmacology. PMID 35703154 DOI: 10.1111/bph.15893 |
0.133 |
|
| 2023 |
Kennett A, Epple S, van der Valk G, Georgiou I, Gout E, Vivès RR, Russell AJ. Modified minimal-size fragments of heparan sulfate as inhibitors of endosulfatase-2 (Sulf-2). Chemical Communications (Cambridge, England). PMID 38086706 DOI: 10.1039/d3cc02565a |
0.126 |
|
| 2023 |
Madden KS, Todd PMT, Urata K, Russell AJ, Vincent KA, Reeve HA. A pharmacophore-based approach to demonstrating the scope of alcohol dehydrogenases. Bioorganic & Medicinal Chemistry. 83: 117255. PMID 36966660 DOI: 10.1016/j.bmc.2023.117255 |
0.125 |
|
| 2024 |
Kennett A, Epple S, van der Valk G, Georgiou I, Gout E, Vivès RR, Russell AJ. Correction: Modified minimal-size fragments of heparan sulfate as inhibitors of endosulfatase-2 (Sulf-2). Chemical Communications (Cambridge, England). PMID 38602132 DOI: 10.1039/d4cc90123a |
0.12 |
|
| 2022 |
Silpa L, Sim R, Russell AJ. Recent advances in small molecule stimulation of regeneration and repair. Bioorganic & Medicinal Chemistry Letters. 61: 128601. PMID 35123003 DOI: 10.1016/j.bmcl.2022.128601 |
0.117 |
|
| 2021 |
Bery N, Bataille CJR, Russell A, Hayes A, Raynaud F, Milhas S, Anand S, Tulmin H, Miller A, Rabbitts TH. A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2. Science Advances. 7. PMID 33837087 DOI: 10.1126/sciadv.abg1950 |
0.111 |
|
| 2013 |
Russell AJ. Regenerative medicinal chemistry: The in situ control of stem cells Acs Medicinal Chemistry Letters. 4: 365-368. DOI: 10.1021/ml400110b |
0.109 |
|
| 2020 |
Luscombe VB, Lucy D, Bataille CJR, Russell AJ, Greaves DR. 20 Years an Orphan: Is GPR84 a Plausible Medium-Chain Fatty Acid-Sensing Receptor? Dna and Cell Biology. 39: 1926-1937. PMID 33001759 DOI: 10.1089/dna.2020.5846 |
0.107 |
|
| 2023 |
Luscombe VB, Wang P, Russell AJ, Greaves DR. Biased agonists of GPR84 and insights into biological control. British Journal of Pharmacology. PMID 38148720 DOI: 10.1111/bph.16310 |
0.1 |
|
| 2020 |
Wilkinson IVL, Terstappen GC, Russell AJ. Combining experimental strategies for successful target deconvolution. Drug Discovery Today. PMID 32971235 DOI: 10.1016/j.drudis.2020.09.016 |
0.098 |
|
| 2023 |
Luscombe VB, Baena-López LA, Bataille CJR, Russell AJ, Greaves DR. Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory G-protein coupled receptor GPR84. European Journal of Pharmacology. 956: 175960. PMID 37543157 DOI: 10.1016/j.ejphar.2023.175960 |
0.092 |
|
| 2008 |
Roos A, Barr A, King O, Ugochukwu E, Russell A, Knapp S, von Delft F. A family-wide approach to structure-based inhibitor design for protein tyrosine phosphatases Acta Crystallographica Section a Foundations of Crystallography. 64: C38-C38. DOI: 10.1107/S0108767308098796 |
0.081 |
|
| 2022 |
Bose SJ, Read MJ, Akerman E, Capel RA, Ayagama T, Russell A, Terrar DA, Zaccolo M, Burton RAB. Inhibition of adenylyl cyclase 1 by ST034307 inhibits IP-evoked changes in sino-atrial node beat rate. Frontiers in Pharmacology. 13: 951897. PMID 36105228 DOI: 10.3389/fphar.2022.951897 |
0.079 |
|
| 2021 |
Dinsdale RL, Pipatpolkai T, Agostinelli E, Russell AJ, Stansfeld PJ, Tammaro P. An outer-pore gate modulates the pharmacology of the TMEM16A channel. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34413188 DOI: 10.1073/pnas.2023572118 |
0.067 |
|
| 2023 |
Brimblecombe KR, Connor-Robson N, Bataille CJR, Roberts BM, Gracie C, O'Connor B, Te Water Naude R, Karthik G, Russell AJ, Wade-Martins R, Cragg SJ. Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's. The European Journal of Neuroscience. PMID 37941514 DOI: 10.1111/ejn.16180 |
0.064 |
|
| 1977 |
Sumner DJ, Russell AJ. Digoxin pharmacokinetics: multicompartmental analysis and its clinical implications. British Journal of Clinical Pharmacology. 3: 221-9. PMID 973956 DOI: 10.1111/J.1365-2125.1976.TB00596.X |
0.059 |
|
| 2017 |
Russell A, Yaraskavitch M, Fok D, Chhibber S, Street L, Korngut L. Obinutuzumab Plus Chlorambucil in a Patient with Severe Myasthenia Gravis and Chronic Lymphocytic Leukemia. Journal of Neuromuscular Diseases. 4: 251-257. PMID 28869483 DOI: 10.3233/JND-170211 |
0.058 |
|
| 2018 |
Bery N, Cruz-Migoni A, Bataille CJ, Quevedo CE, Tulmin H, Miller A, Russell A, Phillips SE, Carr SB, Rabbitts TH. Correction: BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. Elife. 7. PMID 30074480 DOI: 10.7554/eLife.40515 |
0.057 |
|
| 2002 |
Russell AJ, Bidartondo MI, Butterfield BG. The root nodules of the Podocarpaceae harbour arbuscular mycorrhizal fungi. The New Phytologist. 156: 283-295. PMID 33873271 DOI: 10.1046/j.1469-8137.2002.00504.x |
0.05 |
|
| 2020 |
Russell A, Hahn C, Chhibber S, Korngut L, Fine NM. Utility of Neuropathy Screening for Wild-Type Transthyretin Amyloidosis Patients. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 1-30. PMID 33342448 DOI: 10.1017/cjn.2020.271 |
0.047 |
|
| 2022 |
Conway SJ, Kawamura A, Marr TM, Platt F, Russell AJ. Increasing Diversity in Admissions to Postgraduate Study. Journal of Medicinal Chemistry. 65: 5867-5869. PMID 35438504 DOI: 10.1021/acs.jmedchem.2c00533 |
0.04 |
|
| 2022 |
Russell A, Taylor MD, Barnes TC, Johnson DD, Gillanders BM. Habitat transitions by a large coastal sciaenid across life history stages, resolved using otolith chemistry. Marine Environmental Research. 176: 105614. PMID 35381507 DOI: 10.1016/j.marenvres.2022.105614 |
0.039 |
|
| 2004 |
Malow RM, Jean-Gilles MM, Devieux JG, Rosenberg R, Russell A. Increasing access to preventive health care through cultural adaptation of effective HIV prevention interventions: a brief report from the HIV prevention in Haitian youths study. The Abnf Journal : Official Journal of the Association of Black Nursing Faculty in Higher Education, Inc. 15: 127-32. PMID 18399363 |
0.039 |
|
| 2005 |
Papapetropoulos S, Lopez-Alberola R, Baumbach L, Russell A, Gonzalez MA, Bowen BC, Singer C. Case of maternally transmitted juvenile Huntington's disease with a very large trinucleotide repeat. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 1380-3. PMID 16007623 DOI: 10.1002/mds.20557 |
0.038 |
|
| 2023 |
Russell A, Khayambashi S, Fine NM, Chhibber S, Hahn C. Characteristics of Carpal Tunnel Syndrome in Wild-Type Transthyretin Amyloidosis. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 1-13. PMID 37555238 DOI: 10.1017/cjn.2023.268 |
0.015 |
|
| 2002 |
Alpay L, Russell A. Information technology training in primary care: the nurses' voice. Computers, Informatics, Nursing : Cin. 20: 136-42. PMID 12105401 DOI: 10.1097/00024665-200207000-00008 |
0.015 |
|
| 2005 |
Parker EJ, Misan G, Richards LC, Russell A. Planning and implementing the first stage of an oral health program for the Pika Wiya Health Service Incorporated Aboriginal community in Port Augusta, South Australia. Rural and Remote Health. 5: 254. PMID 15885023 |
0.014 |
|
| 2006 |
Gasiorowicz M, Hurie M, Russell A, Hoxie N, Vergeront J. Epidemiologic trends in infection, mortality, and transplants related to hepatitis C in Wisconsin. Wmj : Official Publication of the State Medical Society of Wisconsin. 105: 34-9. PMID 16676489 |
0.013 |
|
| 2014 |
Mizell D, Washington-Brown LJ, Russell A. Transitioning RN to BSN students from acute care to hospice care nursing. The Abnf Journal : Official Journal of the Association of Black Nursing Faculty in Higher Education, Inc. 25: 103-9. PMID 25612396 |
0.01 |
|
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