| Year |
Citation |
Score |
| 2024 |
Kumar S, Rastogi SK, Roy S, Sharma K, Kumar S, Maity D, Chand D, Vishwakarma S, Gayen JR, Srivastava KR, Kumar R, Yadav PN. Discovery and structure - activity relationships of 2,4,5-trimethoxyphenyl pyrimidine derivatives as selective D5 receptor partial agonists. Bioorganic Chemistry. 153: 107809. PMID 39270528 DOI: 10.1016/j.bioorg.2024.107809 |
0.327 |
|
| 2024 |
Singh K, Yadav A, Khan S, Shukla A, Alam M, Verma AK, Tiwari N, Khan F, Yadav PN, Dev K. Baicalein isolated from acts as a potent µ- and κ-opioid receptor antagonist agent via the reversal of agonist-mediated cAMP inhibition. Natural Product Research. 1-9. PMID 39205489 DOI: 10.1080/14786419.2024.2396452 |
0.413 |
|
| 2024 |
Saha S, Khanppnavar B, Maharana J, Kim H, Carino CMC, Daly C, Houston S, Sharma S, Zaidi N, Dalal A, Mishra S, Ganguly M, Tiwari D, Kumari P, Jhingan GD, ... Yadav PN, et al. Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor. Cell. PMID 39089252 DOI: 10.1016/j.cell.2024.07.005 |
0.343 |
|
| 2023 |
Sarma P, Carino CMC, Seetharama D, Pandey S, Dwivedi-Agnihotri H, Rui X, Cao Y, Kawakami K, Kumari P, Chen YC, Luker KE, Yadav PN, Luker GD, Laporte SA, Chen X, et al. Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system. Nature Communications. 14: 4808. PMID 37558722 DOI: 10.1038/s41467-023-40482-9 |
0.394 |
|
| 2022 |
Yadav A, Yadav A, Tripathi S, Dewaker V, Kant R, Yadav PN, Srivastava AK. Copper-Catalyzed Oxidative [3 + 2]-Annulation of Quinoxalin-2(1)-one with Oxime Esters toward Functionalized Pyrazolo[1,5-]quinoxalin-4(5)-ones as Opioid Receptor Modulators. The Journal of Organic Chemistry. 87: 7350-7364. PMID 35587158 DOI: 10.1021/acs.joc.2c00563 |
0.396 |
|
| 2021 |
Batra S, Yadav VD, Kumar L, Kumari P, Kumar S, Singh M, Siddiqi MI, Yadav PN. Synthesis and Assessment of fused β-carboline derivatives as Kappa Opioid Receptor agonist. Chemmedchem. PMID 33599108 DOI: 10.1002/cmdc.202100029 |
0.391 |
|
| 2021 |
Batra S, Yadav VD, Kumar L, Kumari P, Kumar S, Singh M, Siddiqi MI, Yadav PN. Synthesis and Assessment of fused β-carboline derivatives as Kappa Opioid Receptor agonist. Chemmedchem. PMID 33599108 DOI: 10.1002/cmdc.202100029 |
0.391 |
|
| 2021 |
Yadav VD, Kumar L, Kumari P, Kumar S, Singh M, Siddiqi MI, Yadav PN, Batra S. Cover Feature: Synthesis and Assessment of Fused β‐Carboline Derivatives as Kappa Opioid Receptor Agonists (12/2021) Chemmedchem. 16: 1834-1834. DOI: 10.1002/CMDC.202100380 |
0.417 |
|
| 2018 |
Sudarshan K, Boda AK, Dogra S, Bose I, Yadav PN, Aidhen IS. Discovery of an isocoumarin analogue that modulates neuronal functions via neurotrophin receptor TrkB. Bioorganic & Medicinal Chemistry Letters. PMID 30600206 DOI: 10.1016/j.bmcl.2018.12.057 |
0.338 |
|
| 2018 |
Singh LR, Kumar A, Upadhyay A, Gupta S, Palanati GR, Sikka K, Siddiqi MI, Yadav PN, Sashidhara KV. Discovery of coumarin-dihydroquinazolinone analogs as niacin receptor 1 agonist with in-vivo anti-obesity efficacy. European Journal of Medicinal Chemistry. 152: 208-222. PMID 29709786 DOI: 10.1016/j.ejmech.2018.04.037 |
0.311 |
|
| 2018 |
Singh LR, Kumar A, Upadhyay A, Gupta S, Palanati GR, Sikka K, Siddiqi MI, Yadav PN, Sashidhara KV. Discovery of coumarin-dihydroquinazolinone analogs as niacin receptor 1 agonist with in-vivo anti-obesity efficacy. European Journal of Medicinal Chemistry. 152: 208-222. PMID 29709786 DOI: 10.1016/j.ejmech.2018.04.037 |
0.311 |
|
| 2018 |
Varkhedkar R, Dogra S, Tiwari D, Hussain Y, Yadav PN, Pandey G. Discovery of Novel Muscarinic Receptor Modulators by Integrating Natural Product Framework with Bioactive Molecule. Chemmedchem. PMID 29319226 DOI: 10.1002/cmdc.201800001 |
0.31 |
|
| 2017 |
Ravilla L, Venkata Subba Naidu N, Dogra S, Umrao D, Yadav PN, Biswas A, Michael D, Sekar K, Nagarajan K. Opioid receptor modulators with a cinnamyl group. Journal of Medicinal Chemistry. PMID 28726402 DOI: 10.1021/Acs.Jmedchem.7B00643 |
0.422 |
|
| 2017 |
Ravilla L, Venkata Subba Naidu N, Dogra S, Umrao D, Yadav PN, Biswas A, Michael D, Sekar K, Nagarajan K. Opioid receptor modulators with a cinnamyl group. Journal of Medicinal Chemistry. PMID 28726402 DOI: 10.1021/Acs.Jmedchem.7B00643 |
0.422 |
|
| 2017 |
Kumari P, Srivastava A, Ghosh E, Ranjan R, Dogra S, Yadav PN, Shukla AK. Core engagement with β-arrestin is dispensable for agonist induced vasopressin receptor endocytosis and ERK activation. Molecular Biology of the Cell. PMID 28228552 DOI: 10.1091/Mbc.E16-12-0818 |
0.368 |
|
| 2017 |
Kumari P, Srivastava A, Ghosh E, Ranjan R, Dogra S, Yadav PN, Shukla AK. Core engagement with β-arrestin is dispensable for agonist induced vasopressin receptor endocytosis and ERK activation. Molecular Biology of the Cell. PMID 28228552 DOI: 10.1091/Mbc.E16-12-0818 |
0.368 |
|
| 2015 |
Dogra S, Yadav PN. Biased agonism at kappa opioid receptors: Implication in pain and mood disorders. European Journal of Pharmacology. 763: 184-90. PMID 26164787 DOI: 10.1016/j.ejphar.2015.07.018 |
0.338 |
|
| 2015 |
Dogra S, Yadav PN. Biased agonism at kappa opioid receptors: Implication in pain and mood disorders. European Journal of Pharmacology. 763: 184-90. PMID 26164787 DOI: 10.1016/j.ejphar.2015.07.018 |
0.338 |
|
| 2014 |
Singh N, Yadav M, Singh AK, Kumar H, Dwivedi SK, Mishra JS, Gurjar A, Manhas A, Chandra S, Yadav PN, Jagavelu K, Siddiqi MI, Trivedi AK, Chattopadhyay N, Sanyal S. Synthetic FXR agonist GW4064 is a modulator of multiple G protein-coupled receptors. Molecular Endocrinology (Baltimore, Md.). 28: 659-73. PMID 24597548 DOI: 10.1210/me.2013-1353 |
0.415 |
|
| 2013 |
Farrell MS, Pei Y, Wan Y, Yadav PN, Daigle TL, Urban DJ, Lee HM, Sciaky N, Simmons A, Nonneman RJ, Huang XP, Hufeisen SJ, Guettier JM, Moy SS, Wess J, et al. A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 854-62. PMID 23303063 DOI: 10.1038/Npp.2012.251 |
0.451 |
|
| 2013 |
Goldsmith JR, Perez-Chanona E, Yadav PN, Whistler J, Roth B, Jobin C. Intestinal epithelial cell-derived μ-opioid signaling protects against ischemia reperfusion injury through PI3K signaling. The American Journal of Pathology. 182: 776-85. PMID 23291213 DOI: 10.1016/J.Ajpath.2012.11.021 |
0.48 |
|
| 2013 |
Goldsmith JR, Perez-Chanona E, Yadav PN, Whistler J, Roth B, Jobin C. Intestinal epithelial cell-derived μ-opioid signaling protects against ischemia reperfusion injury through PI3K signaling. The American Journal of Pathology. 182: 776-85. PMID 23291213 DOI: 10.1016/J.Ajpath.2012.11.021 |
0.48 |
|
| 2012 |
Goldsmith JR, Chanona EP, Yadav PN, Whistler JL, Roth B, Jobin C. Sa1939 Intestinal Epithelial Cell (IEC)-Derived Mu-Opioid Signaling is Protective Against Ischemia Reperfusion (I/R) Induced Injury Gastroenterology. 142: S-364. DOI: 10.1016/S0016-5085(12)61373-0 |
0.468 |
|
| 2012 |
Yadav PN, Whistler J, Roth BL. ISDN2012_0285: Cellular mechanisms of salvinorin A action
in vivo International Journal of Developmental Neuroscience. 30: 689-689. DOI: 10.1016/J.Ijdevneu.2012.10.056 |
0.334 |
|
| 2011 |
Allen JA, Yadav PN, Setola V, Farrell M, Roth BL. Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo. Translational Psychiatry. 1: e33. PMID 22832607 DOI: 10.1038/Tp.2011.35 |
0.492 |
|
| 2011 |
Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/Pnas.1104807108 |
0.467 |
|
| 2011 |
Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/Pnas.1104807108 |
0.467 |
|
| 2011 |
Yadav PN, Kroeze WK, Farrell MS, Roth BL. Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo. The Journal of Pharmacology and Experimental Therapeutics. 339: 99-105. PMID 21737536 DOI: 10.1124/jpet.111.183780 |
0.525 |
|
| 2011 |
Yadav PN, Kroeze WK, Farrell MS, Roth BL. Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo. The Journal of Pharmacology and Experimental Therapeutics. 339: 99-105. PMID 21737536 DOI: 10.1124/jpet.111.183780 |
0.525 |
|
| 2011 |
Yadav PN, Abbas AI, Farrell MS, Setola V, Sciaky N, Huang XP, Kroeze WK, Crawford LK, Piel DA, Keiser MJ, Irwin JJ, Shoichet BK, Deneris ES, Gingrich J, Beck SG, et al. The presynaptic component of the serotonergic system is required for clozapine's efficacy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 638-51. PMID 21048700 DOI: 10.1038/Npp.2010.195 |
0.434 |
|
| 2011 |
Yadav PN, Abbas AI, Farrell MS, Setola V, Sciaky N, Huang XP, Kroeze WK, Crawford LK, Piel DA, Keiser MJ, Irwin JJ, Shoichet BK, Deneris ES, Gingrich J, Beck SG, et al. The presynaptic component of the serotonergic system is required for clozapine's efficacy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 638-51. PMID 21048700 DOI: 10.1038/Npp.2010.195 |
0.434 |
|
| 2010 |
Magalhaes AC, Holmes KD, Dale LB, Comps-Agrar L, Lee D, Yadav PN, Drysdale L, Poulter MO, Roth BL, Pin JP, Anisman H, Ferguson SS. CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling. Nature Neuroscience. 13: 622-9. PMID 20383137 DOI: 10.1038/Nn.2529 |
0.506 |
|
| 2010 |
Magalhaes AC, Holmes KD, Dale LB, Comps-Agrar L, Lee D, Yadav PN, Drysdale L, Poulter MO, Roth BL, Pin JP, Anisman H, Ferguson SS. CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling. Nature Neuroscience. 13: 622-9. PMID 20383137 DOI: 10.1038/Nn.2529 |
0.506 |
|
| 2009 |
Huang XP, Setola V, Yadav PN, Allen JA, Rogan SC, Hanson BJ, Revankar C, Robers M, Doucette C, Roth BL. Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment. Molecular Pharmacology. 76: 710-22. PMID 19570945 DOI: 10.1124/Mol.109.058057 |
0.521 |
|
| 2009 |
Huang XP, Setola V, Yadav PN, Allen JA, Rogan SC, Hanson BJ, Revankar C, Robers M, Doucette C, Roth BL. Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment. Molecular Pharmacology. 76: 710-22. PMID 19570945 DOI: 10.1124/Mol.109.058057 |
0.521 |
|
| 2009 |
Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL. PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7124-36. PMID 19494135 DOI: 10.1523/Jneurosci.1090-09.2009 |
0.492 |
|
| 2009 |
Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL. PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7124-36. PMID 19494135 DOI: 10.1523/Jneurosci.1090-09.2009 |
0.492 |
|
| 2008 |
Wannemacher KM, Terskiy A, Bian S, Yadav PN, Li H, Howells RD. Purification and mass spectrometric analysis of the kappa opioid receptor. Brain Research. 1230: 13-26. PMID 18656460 DOI: 10.1016/j.brainres.2008.06.121 |
0.775 |
|
| 2008 |
Wannemacher KM, Terskiy A, Bian S, Yadav PN, Li H, Howells RD. Purification and mass spectrometric analysis of the kappa opioid receptor. Brain Research. 1230: 13-26. PMID 18656460 DOI: 10.1016/j.brainres.2008.06.121 |
0.775 |
|
| 2008 |
Allen JA, Yadav PN, Roth BL. Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases. Neuropharmacology. 55: 961-8. PMID 18640136 DOI: 10.1016/j.neuropharm.2008.06.048 |
0.52 |
|
| 2008 |
Allen JA, Yadav PN, Roth BL. Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases. Neuropharmacology. 55: 961-8. PMID 18640136 DOI: 10.1016/j.neuropharm.2008.06.048 |
0.52 |
|
| 2007 |
Terskiy A, Wannemacher KM, Yadav PN, Tsai M, Tian B, Howells RD. Search of the human proteome for endomorphin-1 and endomorphin-2 precursor proteins. Life Sciences. 81: 1593-601. PMID 17964607 DOI: 10.1016/J.LFS.2007.09.025 |
0.731 |
|
| 2007 |
Terskiy A, Wannemacher KM, Yadav PN, Tsai M, Tian B, Howells RD. Search of the human proteome for endomorphin-1 and endomorphin-2 precursor proteins. Life Sciences. 81: 1593-601. PMID 17964607 DOI: 10.1016/J.LFS.2007.09.025 |
0.731 |
|
| 2007 |
Wannemacher KM, Yadav PN, Howells RD. A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa-opioid receptor in human embryonic kidney 293 cells. The Journal of Pharmacology and Experimental Therapeutics. 323: 614-25. PMID 17720886 DOI: 10.1124/JPET.107.125500 |
0.771 |
|
| 2007 |
Wannemacher KM, Yadav PN, Howells RD. A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa-opioid receptor in human embryonic kidney 293 cells. The Journal of Pharmacology and Experimental Therapeutics. 323: 614-25. PMID 17720886 DOI: 10.1124/JPET.107.125500 |
0.771 |
|
| 2006 |
Yadav PN, Chaturvedi K, Howells RD. Inhibition of agonist-induced down-regulation of the delta-opioid receptor with a proteasome inhibitor attenuates opioid tolerance in human embryonic kidney 293 cells. The Journal of Pharmacology and Experimental Therapeutics. 320: 1186-94. PMID 17159161 DOI: 10.1124/jpet.106.113621 |
0.768 |
|
| 2006 |
Yadav PN, Chaturvedi K, Howells RD. Inhibition of agonist-induced down-regulation of the delta-opioid receptor with a proteasome inhibitor attenuates opioid tolerance in human embryonic kidney 293 cells. The Journal of Pharmacology and Experimental Therapeutics. 320: 1186-94. PMID 17159161 DOI: 10.1124/jpet.106.113621 |
0.768 |
|
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