Eric Blalock - Publications

Affiliations: 
Pharmacology University of Kentucky, Lexington, KY 

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Porter N, Brewer L, Anderson K, Hoffman J, Thibault J, Gant J, Frazier H, Ghower A, Kraner S, Landfield P, Blalock E, Thibault O. Sexually Dimorphic Effects of Dietary Vitamin D3 Supplementation on Cognition and the Gut Microbiome in Aging Rats (P14-006-19). Current Developments in Nutrition. 3. PMID 31223956 DOI: 10.1093/cdn/nzz052.P14-006-19  0.778
2019 Frazier HN, Ghoweri AO, Sudkamp E, Johnson ES, Anderson KL, Fox G, Vatthanaphone K, Xia M, Lin RL, Hargis-Staggs KE, Porter NM, Pauly JR, Blalock EM, Thibault O. Long-term intranasal insulin aspart: a profile of gene expression, memory, and insulin receptors in aged F344 rats. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 31180116 DOI: 10.1093/Gerona/Glz105  0.623
2018 Gant JC, Kadish I, Chen KC, Thibault O, Blalock EM, Porter NM, Landfield PW. Aging-Related Calcium Dysregulation in Rat Entorhinal Neurons Homologous with the Human Entorhinal Neurons in which Alzheimer's Disease Neurofibrillary Tangles First Appear. Journal of Alzheimer's Disease : Jad. PMID 30412490 DOI: 10.3233/Jad-180618  0.823
2018 Hargis K, Buechel HM, Popovic J, Blalock EM. Acute psychosocial stress in mid-aged male rats causes hyperthermia, cognitive decline, and increased deep sleep power, but does not alter deep sleep duration. Neurobiology of Aging. 70: 78-85. PMID 30007167 DOI: 10.1016/j.neurobiolaging.2018.06.009  0.801
2017 Gant JC, Blalock EM, Chen KC, Kadish I, Thibault O, Porter NM, Landfield PW. FK506-Binding Protein 12.6/1b, a negative regulator of [Ca2+], rescues memory and restores genomic regulation in the hippocampus of aging rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29255009 DOI: 10.1523/Jneurosci.2234-17.2017  0.834
2017 Hargis KE, Blalock EM. Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us? Behavioural Brain Research. 322: 311-328. PMID 27155503 DOI: 10.1016/j.bbr.2016.05.007  0.327
2015 Gant JC, Chen KC, Kadish I, Blalock EM, Thibault O, Porter NM, Landfield PW. Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 10878-87. PMID 26224869 DOI: 10.1523/Jneurosci.1248-15.2015  0.837
2015 Maimaiti S, Anderson KL, DeMoll C, Brewer LD, Rauh BA, Gant JC, Blalock EM, Porter NM, Thibault O. Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25659889 DOI: 10.1093/Gerona/Glu314  0.787
2014 Latimer CS, Brewer LD, Searcy JL, Chen KC, Popovi? J, Kraner SD, Thibault O, Blalock EM, Landfield PW, Porter NM. Vitamin D prevents cognitive decline and enhances hippocampal synaptic function in aging rats. Proceedings of the National Academy of Sciences of the United States of America. 111: E4359-66. PMID 25267625 DOI: 10.1073/Pnas.1404477111  0.748
2014 Buechel HM, Popovic J, Staggs K, Anderson KL, Thibault O, Blalock EM. Aged rats are hypo-responsive to acute restraint: implications for psychosocial stress in aging. Frontiers in Aging Neuroscience. 6: 13. PMID 24575039 DOI: 10.3389/Fnagi.2014.00013  0.798
2014 Gant JC, Blalock EM, Chen KC, Kadish I, Porter NM, Norris CM, Thibault O, Landfield PW. FK506-binding protein 1b/12.6: a key to aging-related hippocampal Ca2+ dysregulation? European Journal of Pharmacology. 739: 74-82. PMID 24291098 DOI: 10.1016/J.Ejphar.2013.10.070  0.817
2013 Chen KC, Blalock EM, Curran-Rauhut MA, Kadish I, Blalock SJ, Brewer L, Porter NM, Landfield PW. Glucocorticoid-dependent hippocampal transcriptome in male rats: pathway-specific alterations with aging. Endocrinology. 154: 2807-20. PMID 23736296 DOI: 10.1210/En.2013-1139  0.692
2013 Pancani T, Anderson KL, Brewer LD, Kadish I, DeMoll C, Landfield PW, Blalock EM, Porter NM, Thibault O. Effect of high-fat diet on metabolic indices, cognition, and neuronal physiology in aging F344 rats. Neurobiology of Aging. 34: 1977-87. PMID 23545425 DOI: 10.1016/J.Neurobiolaging.2013.02.019  0.783
2012 Porter NM, Bohannon JH, Curran-Rauhut M, Buechel HM, Dowling AL, Brewer LD, Popovic J, Thibault V, Kraner SD, Chen KC, Blalock EM. Hippocampal CA1 transcriptional profile of sleep deprivation: relation to aging and stress. Plos One. 7: e40128. PMID 22792227 DOI: 10.1371/journal.pone.0040128  0.789
2012 Searcy JL, Phelps JT, Pancani T, Kadish I, Popovic J, Anderson KL, Beckett TL, Murphy MP, Chen KC, Blalock EM, Landfield PW, Porter NM, Thibault O. Long-term pioglitazone treatment improves learning and attenuates pathological markers in a mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 30: 943-61. PMID 22495349 DOI: 10.3233/Jad-2012-111661  0.744
2011 Latimer CS, Searcy JL, Bridges MT, Brewer LD, Popovi? J, Blalock EM, Landfield PW, Thibault O, Porter NM. Reversal of glial and neurovascular markers of unhealthy brain aging by exercise in middle-aged female mice. Plos One. 6: e26812. PMID 22046366 DOI: 10.1371/Journal.Pone.0026812  0.761
2011 Blalock EM, Buechel HM, Popovic J, Geddes JW, Landfield PW. Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease. Journal of Chemical Neuroanatomy. 42: 118-26. PMID 21756998 DOI: 10.1016/J.Jchemneu.2011.06.007  0.784
2011 Buechel HM, Popovic J, Searcy JL, Porter NM, Thibault O, Blalock EM. Deep sleep and parietal cortex gene expression changes are related to cognitive deficits with age. Plos One. 6: e18387. PMID 21483696 DOI: 10.1371/Journal.Pone.0018387  0.787
2011 Gant JC, Chen KC, Norris CM, Kadish I, Thibault O, Blalock EM, Porter NM, Landfield PW. Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1693-703. PMID 21289178 DOI: 10.1523/Jneurosci.4805-10.2011  0.824
2011 Blalock E, Buechel H, Popovic J, Geddes J, Landfield P. P4-001: Transcriptional profile of a neuronally enriched region of CA1 as a function of progressing Alzheimer's disease Alzheimer's & Dementia. 7: S698-S699. DOI: 10.1016/J.Jalz.2011.05.2020  0.617
2010 Blalock EM, Phelps JT, Pancani T, Searcy JL, Anderson KL, Gant JC, Popovic J, Avdiushko MG, Cohen DA, Chen KC, Porter NM, Thibault O. Effects of long-term pioglitazone treatment on peripheral and central markers of aging. Plos One. 5: e10405. PMID 20454453 DOI: 10.1371/Journal.Pone.0010405  0.833
2010 Blalock EM, Grondin R, Chen KC, Thibault O, Thibault V, Pandya JD, Dowling A, Zhang Z, Sullivan P, Porter NM, Landfield PW. Aging-related gene expression in hippocampus proper compared with dentate gyrus is selectively associated with metabolic syndrome variables in rhesus monkeys. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6058-71. PMID 20427664 DOI: 10.1523/Jneurosci.3956-09.2010  0.804
2010 Norris CM, Blalock EM, Chen KC, Porter NM, Thibault O, Kraner SD, Landfield PW. Hippocampal 'zipper' slice studies reveal a necessary role for calcineurin in the increased activity of L-type Ca(2+) channels with aging. Neurobiology of Aging. 31: 328-38. PMID 18471936 DOI: 10.1016/J.Neurobiolaging.2008.03.026  0.793
2010 Blalock EM, Dowling ALS, Martin S, Popovic J, Barrett EG, Head E. Transcriptional profile of the aging canine brain Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.673  0.301
2009 Brewer LD, Dowling AL, Curran-Rauhut MA, Landfield PW, Porter NM, Blalock EM. Estradiol reverses a calcium-related biomarker of brain aging in female rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6058-67. PMID 19439583 DOI: 10.1523/Jneurosci.5253-08.2009  0.719
2009 Kadish I, Thibault O, Blalock EM, Chen KC, Gant JC, Porter NM, Landfield PW. Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1805-16. PMID 19211887 DOI: 10.1523/Jneurosci.4599-08.2009  0.815
2009 Gant JC, Thibault O, Blalock EM, Yang J, Bachstetter A, Kotick J, Schauwecker PE, Hauser KF, Smith GM, Mervis R, Li Y, Barnes GN. Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. Epilepsia. 50: 629-45. PMID 18657176 DOI: 10.1111/J.1528-1167.2008.01725.X  0.694
2009 Searcy JL, Latimer CS, Thibault O, Blalock EM, Chen K, Kadish I, Landfeild PW, Porter NM. P2-257: Long-term effects of simvastatin and atorvastatin on a rat model of normal brain aging Alzheimer's & Dementia. 5: P335-P335. DOI: 10.1016/J.Jalz.2009.04.571  0.647
2008 Searcy JL, Phelps JT, Blalock EM, Dowling AL, Chen KC, Landfield PW, Thibault O, Kadish I, Porter NM. P2-463: LXR agonist treatment of a transgenic mouse model of Alzheimer's disease: Effects on behavioral, electrophysiological and immunohistochemical markers Alzheimer's & Dementia. 4: T510-T510. DOI: 10.1016/J.Jalz.2008.05.1542  0.734
2008 Phelps JT, Searcy JL, Pancani T, Blalock EM, Chen K, Porter NM, Thibault O. P2-457: Effect of chronic treatment with the PPAR-G agonist, pioglitazone, in a triple transgenic model of Alzheimer's disease Alzheimer's & Dementia. 4: T508-T508. DOI: 10.1016/J.Jalz.2008.05.1536  0.58
2007 Landfield PW, Blalock EM, Chen KC, Porter NM. A new glucocorticoid hypothesis of brain aging: implications for Alzheimer's disease. Current Alzheimer Research. 4: 205-12. PMID 17430248 DOI: 10.2174/156720507780362083  0.694
2007 Rowe WB, Blalock EM, Chen KC, Kadish I, Wang D, Barrett JE, Thibault O, Porter NM, Rose GM, Landfield PW. Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3098-110. PMID 17376971 DOI: 10.1523/Jneurosci.4163-06.2007  0.77
2006 Norris CM, Blalock EM, Thibault O, Brewer LD, Clodfelter GV, Porter NM, Landfield PW. Electrophysiological mechanisms of delayed excitotoxicity: positive feedback loop between NMDA receptor current and depolarization-mediated glutamate release. Journal of Neurophysiology. 96: 2488-500. PMID 16914613 DOI: 10.1152/Jn.00593.2005  0.741
2006 Kelly KM, Nadon NL, Morrison JH, Thibault O, Barnes CA, Blalock EM. The neurobiology of aging. Epilepsy Research. 68: S5-20. PMID 16386406 DOI: 10.1016/J.Eplepsyres.2005.07.015  0.735
2005 Blalock EM, Chen KC, Stromberg AJ, Norris CM, Kadish I, Kraner SD, Porter NM, Landfield PW. Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: statistical reliability and functional correlation. Ageing Research Reviews. 4: 481-512. PMID 16257272 DOI: 10.1016/J.Arr.2005.06.006  0.658
2005 Norris CM, Kadish I, Blalock EM, Chen KC, Thibault V, Porter NM, Landfield PW, Kraner SD. Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4649-58. PMID 15872113 DOI: 10.1523/Jneurosci.0365-05.2005  0.669
2004 Blalock EM, Geddes JW, Chen KC, Porter NM, Markesbery WR, Landfield PW. Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proceedings of the National Academy of Sciences of the United States of America. 101: 2173-8. PMID 14769913 DOI: 10.1073/Pnas.0308512100  0.578
2003 Peng X, Wood CL, Blalock EM, Chen KC, Landfield PW, Stromberg AJ. Statistical implications of pooling RNA samples for microarray experiments. Bmc Bioinformatics. 4: 26. PMID 12823867 DOI: 10.1186/1471-2105-4-26  0.508
2003 Blalock EM, Chen KC, Sharrow K, Herman JP, Porter NM, Foster TC, Landfield PW. Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3807-19. PMID 12736351 DOI: 10.1523/Jneurosci.23-09-03807.2003  0.704
2002 Norris CM, Blalock EM, Chen KC, Porter NM, Landfield PW. Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture. Neuroscience. 110: 213-25. PMID 11958864 DOI: 10.1016/S0306-4522(01)00574-7  0.622
2001 Blalock EM, Chen KC, Vanaman TC, Landfield PW, Slevin JT. Epilepsy-induced decrease of L-type Ca2+ channel activity and coordinate regulation of subunit mRNA in single neurons of rat hippocampal 'zipper' slices. Epilepsy Research. 43: 211-26. PMID 11248533 DOI: 10.1016/S0920-1211(00)00199-6  0.623
2000 Chen KC, Blalock EM, Thibault O, Kaminker P, Landfield PW. Expression of alpha 1D subunit mRNA is correlated with L-type Ca2+ channel activity in single neurons of hippocampal "zipper" slices. Proceedings of the National Academy of Sciences of the United States of America. 97: 4357-62. PMID 10759553 DOI: 10.1073/Pnas.070056097  0.787
1999 Blalock EM, Porter NM, Landfield PW. Decreased G-Protein-Mediated Regulation and Shift in Calcium Channel Types with Age in Hippocampal Cultures The Journal of Neuroscience. 19: 8674-8684. DOI: 10.1523/JNEUROSCI.19-19-08674.1999  0.595
1998 Thibault O, Porter NM, Chen KC, Blalock EM, Kaminker PG, Clodfelter GV, Brewer LD, Landfield PW. Calcium dysregulation in neuronal aging and Alzheimer's disease: history and new directions. Cell Calcium. 24: 417-33. PMID 10091010 DOI: 10.1016/S0143-4160(98)90064-1  0.796
1996 Campbell LW, Hao SY, Thibault O, Blalock EM, Landfield PW. Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6286-95. PMID 8815908 DOI: 10.1523/Jneurosci.16-19-06286.1996  0.812
1995 Thibault O, Mazzanti ML, Blalock EM, Porter NM, Landfield PW. Single-channel and whole-cell studies of calcium currents in young and aged rat hippocampal slice neurons. Journal of Neuroscience Methods. 59: 77-83. PMID 7475254 DOI: 10.1016/0165-0270(94)00196-N  0.788
1994 Thibault O, Mazzanti M, Blalock E, Porter N, Landfield P. 9. Calcium currents at the whole cell and single channel level in young and aged rat hippocampal slice neurons Journal of Neuroscience Methods. 52: A4-A5. DOI: 10.1016/0165-0270(94)90069-8  0.764
1994 Thibault O, Mazzanti ML, Blalock EM, Porter NM, Landfield PW. Brain Neuron Preparations for the Study of Aging Changes in Calcium Potentials and Currents Neuroprotocols. 4: 177-181. DOI: 10.1006/Ncmn.1994.1023  0.774
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