Dan H Barouch, M.D., PhD. - Publications

Affiliations: 
Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States 

315 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jacob-Dolan C, Ty D, Hope D, McMahan K, Liu J, Powers OC, Cotter CA, Sciacca M, Wu C, Borducchi E, Bouffard E, Richter H, Velasco J, Teow E, Boursiquot M, ... ... Barouch DH, et al. Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques. Science Translational Medicine. 16: eadl4317. PMID 38536937 DOI: 10.1126/scitranslmed.adl4317  0.555
2024 Lasrado N, Collier AY, Miller J, Hachmann NP, Liu J, Anand T, A Bondzie E, Fisher JL, Mazurek CR, Patio RC, Rodrigues SL, Rowe M, Surve N, Ty DM, Wu C, ... ... Barouch DH, et al. Waning immunity and IgG4 responses following bivalent mRNA boosting. Science Advances. 10: eadj9945. PMID 38394195 DOI: 10.1126/sciadv.adj9945  0.313
2024 Song NJ, Chakravarthy KB, Jeon H, Bolyard C, Reynolds K, Weller KP, Reisinger S, Wang Y, Li A, Jiang S, Ma Q, Barouch DH, Rubinstein MP, Shields PG, Oltz EM, et al. mRNA vaccines against SARS-CoV-2 induce divergent antigen-specific T-cell responses in patients with lung cancer. Journal For Immunotherapy of Cancer. 12. PMID 38177076 DOI: 10.1136/jitc-2023-007922  0.4
2023 Nkolola JP, Barouch DH. Prophylactic HIV-1 vaccine trials: past, present, and future. The Lancet. Hiv. PMID 38141639 DOI: 10.1016/S2352-3018(23)00264-3  0.436
2023 Fan J, Li S, Zhang Y, Zheng J, Wang D, Liao Y, Cui Z, Zhao D, Barouch DH, Yu J. Early Emerging SARS-CoV-2 Spike Mutants Are Diversified in Virologic Properties but Elicit Compromised Antibody Responses. Viruses. 15. PMID 38140642 DOI: 10.3390/v15122401  0.789
2023 McMahan K, Wegmann F, Aid M, Sciacca M, Liu J, Hachmann NP, Miller J, Jacob-Dolan C, Powers O, Hope D, Wu C, Pereira J, Murdza T, Mazurek CR, Hoyt A, ... ... Barouch DH, et al. Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques. Nature. PMID 38096903 DOI: 10.1038/s41586-023-06951-3  0.568
2023 Aid M, Stephenson KE, Collier AY, Nkolola JP, Michael JV, McKenzie SE, Barouch DH. Activation of coagulation and proinflammatory pathways in thrombosis with thrombocytopenia syndrome and following COVID-19 vaccination. Nature Communications. 14: 6703. PMID 37872311 DOI: 10.1038/s41467-023-42559-x  0.458
2023 Lasrado N, Collier AY, Hachmann NP, Miller J, Rowe M, Schonberg ED, Rodrigues SL, LaPiana A, Patio RC, Anand T, Fisher J, Mazurek CR, Guan R, Wagh K, Theiler J, ... ... Barouch DH, et al. Neutralization escape by SARS-CoV-2 Omicron subvariant BA.2.86. Vaccine. PMID 37872011 DOI: 10.1016/j.vaccine.2023.10.051  0.498
2023 van Duijn J, Stieh D, Fernandez N, King D, Gilmour J, Tolboom J, Callewaert K, Willems W, Pau MG, De Rosa SC, McElrath MJ, Barouch DH, Hayes P. Mosaic HIV-1 vaccination induces anti-viral CD8 T cell functionality in the phase 1/2a clinical trial APPROACH. Journal of Virology. e0112623. PMID 37811993 DOI: 10.1128/jvi.01126-23  0.369
2023 Aid M, Sciacca M, McMahan K, Hope D, Liu J, Jacob-Dolan C, Powers O, Barrett J, Wu C, Mutoni A, Murdza T, Richter H, Velasco J, Teow E, Boursiquot M, ... ... Barouch DH, et al. Mpox infection protects against re-challenge in rhesus macaques. Cell. PMID 37734373 DOI: 10.1016/j.cell.2023.08.023  0.325
2023 Lasrado N, Barouch DH. SARS-CoV-2 Hybrid Immunity: The Best of Both Worlds. The Journal of Infectious Diseases. PMID 37592872 DOI: 10.1093/infdis/jiad353  0.52
2023 Sankhala RS, Dussupt V, Donofrio G, Gromowski GD, De La Barrera RA, Larocca RA, Mendez-Rivera L, Lee A, Choe M, Zaky W, Mantus G, Jensen JL, Chen WH, Gohain N, Bai H, ... ... Barouch DH, et al. Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Reports. 42: 112942. PMID 37561630 DOI: 10.1016/j.celrep.2023.112942  0.41
2023 Vidal SJ, Sellers D, Yu J, Wakabayashi S, Sixsmith J, Aid M, Barrett J, Stevens SF, Liu X, Li W, Plumlee CR, Urdahl KB, Martinot AJ, Barouch DH. Attenuated vaccine protection in a low-dose murine challenge model. Iscience. 26: 106963. PMID 37378347 DOI: 10.1016/j.isci.2023.106963  0.69
2023 Love J, Rodriguez-Aponte S, Tostanoski L, Dalvie N, Johnston R, Jacob-Dolan C, Powers O, Hachmann N, Miller J, Hall K, Siamatu M, Mazurek C, Surve N, Barouch D. SARS-CoV-2 RBD dimers elicit response comparable to VLPs in mice. Research Square. PMID 37163131 DOI: 10.21203/rs.3.rs-2692315/v1  0.381
2023 Vander Straeten A, Sarmadi M, Daristotle JL, Kanelli M, Tostanoski LH, Collins J, Pardeshi A, Han J, Varshney D, Eshaghi B, Garcia J, Forster TA, Li G, Menon N, Pyon SL, ... ... Barouch DH, et al. A microneedle vaccine printer for thermostable COVID-19 mRNA vaccines. Nature Biotechnology. PMID 37095347 DOI: 10.1038/s41587-023-01774-z  0.445
2023 Bartsch YC, Cizmeci D, Kang J, Gao H, Shi W, Chandrashekar A, Collier AY, Chen B, Barouch DH, Alter G. Selective SARS-CoV2 BA.2 escape of antibody Fc/Fc-receptor interactions. Iscience. 26: 106582. PMID 37082529 DOI: 10.1016/j.isci.2023.106582  0.552
2023 Solforosi L, Costes LMM, Tolboom JTBM, McMahan K, Anioke T, Hope D, Murdza T, Sciacca M, Bouffard E, Barrett J, Wu C, Hachmann N, Miller J, Yu J, He X, ... ... Barouch DH, et al. Booster with Ad26.COV2.S or Omicron-adapted vaccine enhanced immunity and efficacy against SARS-CoV-2 Omicron in macaques. Nature Communications. 14: 1944. PMID 37029141 DOI: 10.1038/s41467-023-37715-2  0.757
2023 Yu J, Thomas PV, Sciacca M, Wu C, Liu J, He X, Miller J, Hachmann NP, Surve N, McMahan K, Jacob-Dolan C, Powers O, Hall K, Barrett J, Hope D, ... ... Barouch DH, et al. Ad26.COV2.S and SARS-CoV-2 spike protein ferritin nanoparticle vaccine protect against SARS-CoV-2 Omicron BA.5 challenge in macaques. Cell Reports. Medicine. 101018. PMID 37023746 DOI: 10.1016/j.xcrm.2023.101018  0.758
2023 Cable J, Graham BS, Koup RA, Seder RA, Karikó K, Pardi N, Barouch DH, Sharma B, Rauch S, Nachbagauer R, Forsell MNE, Schotsaert M, Ellebedy AH, Loré K, Irvine DJ, et al. Progress in vaccine development for infectious diseases-a Keystone Symposia report. Annals of the New York Academy of Sciences. 1524: 65-86. PMID 37020354 DOI: 10.1111/nyas.14975  0.459
2023 Nanishi E, Borriello F, Seo HS, O'Meara TR, McGrath ME, Saito Y, Chen J, Diray-Arce J, Song K, Xu AZ, Barman S, Menon M, Dong D, Caradonna TM, Feldman J, ... ... Barouch DH, et al. Publisher Correction: Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. Npj Vaccines. 8: 30. PMID 36869134 DOI: 10.1038/s41541-023-00634-w  0.553
2023 Jacob-Dolan C, Yu J, McMahan K, Giffin V, Chandrashekar A, Martinot AJ, Anioke T, Powers OC, Hall K, Hope D, Miller J, Hachmann NP, Chung B, Gardner S, Sellers D, ... ... Barouch DH, et al. Immunogenicity and protective efficacy of GBP510/AS03 vaccine against SARS-CoV-2 delta challenge in rhesus macaques. Npj Vaccines. 8: 23. PMID 36823160 DOI: 10.1038/s41541-023-00622-0  0.755
2023 Nanishi E, Borriello F, Seo HS, O'Meara TR, McGrath ME, Saito Y, Chen J, Diray-Arce J, Song K, Xu AZ, Barman S, Menon M, Dong D, Caradonna TM, Feldman J, ... ... Barouch DH, et al. Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. Npj Vaccines. 8: 18. PMID 36788219 DOI: 10.1038/s41541-023-00610-4  0.629
2023 Lasrado N, Collier AY, Miller J, Hachmann NP, Liu J, Sciacca M, Wu C, Anand T, Bondzie EA, Fisher JL, Mazurek CR, Patio RC, Powers O, Rodrigues SL, Rowe M, ... ... Barouch DH, et al. Waning Immunity Against XBB.1.5 Following Bivalent mRNA Boosters. Biorxiv : the Preprint Server For Biology. PMID 36747640 DOI: 10.1101/2023.01.22.525079  0.407
2023 Collier AY, Miller J, Hachmann NP, McMahan K, Liu J, Bondzie EA, Gallup L, Rowe M, Schonberg E, Thai S, Barrett J, Borducchi EN, Bouffard E, Jacob-Dolan C, Mazurek CR, ... ... Barouch DH, et al. Immunogenicity of BA.5 Bivalent mRNA Vaccine Boosters. The New England Journal of Medicine. PMID 36630611 DOI: 10.1056/NEJMc2213948  0.427
2022 Cooper A, Sidaway A, Chandrashekar A, Latta E, Chakraborty K, Yu J, McMahan K, Giffin V, Manickam C, Kroll K, Mosher M, Reeves RK, Gam R, Arthofer E, Choudhry M, ... ... Barouch DH, et al. A genetically engineered, stem-cell-derived cellular vaccine. Cell Reports. Medicine. 100843. PMID 36480934 DOI: 10.1016/j.xcrm.2022.100843  0.764
2022 Yu J, Thomas PV, McMahan K, Jacob-Dolan C, Liu J, He X, Hope D, Martinez EJ, Chen WH, Sciacca M, Hachmann NP, Lifton M, Miller J, Powers OC, Hall K, ... ... Barouch DH, et al. Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN. Science Advances. 8: eade4433. PMID 36417525 DOI: 10.1126/sciadv.ade4433  0.736
2022 Nilles EJ, Paulino CT, de St Aubin M, Restrepo AC, Mayfield H, Dumas D, Finch E, Garnier S, Etienne MC, Iselin L, Duke W, Jarolim P, Oasan T, Yu J, Wan H, ... ... Barouch DH, et al. SARS-CoV-2 seroprevalence, cumulative infections, and immunity to symptomatic infection - A multistage national household survey and modelling study, Dominican Republic, June-October 2021. Lancet Regional Health. Americas. 16: 100390. PMID 36408529 DOI: 10.1016/j.lana.2022.100390  0.685
2022 Collier AY, Miller J, Hachmann NP, McMahan K, Liu J, Bondzie EA, Gallup L, Rowe M, Schonberg E, Thai S, Barrett J, Borducchi EN, Bouffard E, Jacob-Dolan C, Mazurek CR, ... ... Barouch DH, et al. Immunogenicity of the BA.5 Bivalent mRNA Vaccine Boosters. Biorxiv : the Preprint Server For Biology. PMID 36324798 DOI: 10.1101/2022.10.24.513619  0.448
2022 Dagotto G, Ventura JD, Martinez DR, Anioke T, Chung BS, Siamatu M, Barrett J, Miller J, Schäfer A, Yu J, Tostanoski LH, Wagh K, Baric RS, Korber B, Barouch DH. Immunogenicity and protective efficacy of a rhesus adenoviral vaccine targeting conserved COVID-19 replication transcription complex. Npj Vaccines. 7: 125. PMID 36302778 DOI: 10.1038/s41541-022-00553-2  0.739
2022 Barouch DH. Covid-19 Vaccines - Immunity, Variants, Boosters. The New England Journal of Medicine. 387: 1011-1020. PMID 36044620 DOI: 10.1056/NEJMra2206573  0.5
2022 Gilbert PB, Huang Y, deCamp AC, Karuna S, Zhang Y, Magaret CA, Giorgi EE, Korber B, Edlefsen PT, Rossenkhan R, Juraska M, Rudnicki E, Kochar N, Huang Y, Carpp LN, ... Barouch DH, et al. Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition. Nature Medicine. PMID 35995954 DOI: 10.1038/s41591-022-01953-6  0.312
2022 Wherry EJ, Barouch DH. T cell immunity to COVID-19 vaccines. Science (New York, N.Y.). 377: 821-822. PMID 35981045 DOI: 10.1126/science.add2897  0.463
2022 Tan CS, Collier AY, Yu J, Liu J, Chandrashekar A, McMahan K, Jacob-Dolan C, He X, Roy V, Hauser BM, Munt JE, Mallory ML, Mattocks M, Powers JM, Meganck RM, ... ... Barouch DH, et al. Durability of Heterologous and Homologous COVID-19 Vaccine Boosts. Jama Network Open. 5: e2226335. PMID 35947380 DOI: 10.1001/jamanetworkopen.2022.26335  0.724
2022 Liu J, Yu J, McMahan K, Jacob-Dolan C, He X, Giffin V, Wu C, Sciacca M, Powers O, Nampanya F, Miller J, Lifton M, Hope D, Hall K, Hachmann NP, ... ... Barouch DH, et al. CD8 T Cells Contribute to Vaccine Protection Against SARS-CoV-2 in Macaques. Science Immunology. eabq7647. PMID 35943359 DOI: 10.1126/sciimmunol.abq7647  0.777
2022 Nanishi E, McGrath ME, O'Meara TR, Barman S, Yu J, Wan H, Dillen CA, Menon M, Seo HS, Song K, Xu AZ, Sebastian L, Brook B, Bosco AN, Borriello F, ... ... Barouch DH, et al. mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant. Communications Biology. 5: 790. PMID 35933439 DOI: 10.1038/s42003-022-03765-3  0.72
2022 Gebre MS, Rauch S, Roth N, Gergen J, Yu J, Liu X, Cole AC, Mueller SO, Petsch B, Barouch DH. mRNA vaccines induce rapid antibody responses in mice. Npj Vaccines. 7: 88. PMID 35915094 DOI: 10.1038/s41541-022-00511-y  0.749
2022 Hartwell BL, Melo MB, Xiao P, Lemnios AA, Li N, Chang JYH, Yu J, Gebre MS, Chang A, Maiorino L, Carter C, Moyer TJ, Dalvie NC, Rodriguez-Aponte SA, Rodrigues KA, ... ... Barouch DH, et al. Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity. Science Translational Medicine. 14: eabn1413. PMID 35857825 DOI: 10.1126/scitranslmed.abn1413  0.718
2022 Nkolola JP, Yu J, Wan H, Chang A, McMahan K, Anioke T, Jacob-Dolan C, Powers O, Ye T, Chandrashekar A, Sellers D, Barrett J, Loo YM, Esser MT, Carnahan RH, ... ... Barouch DH, et al. A bivalent SARS-CoV-2 monoclonal antibody combination does not impact the immunogenicity of a vector-based COVID-19 vaccine in macaques. Science Translational Medicine. eabo6160. PMID 35857623 DOI: 10.1126/scitranslmed.abo6160  0.765
2022 Herman GA, O'Brien MP, Forleo-Neto E, Sarkar N, Isa F, Hou P, Chan KC, Bar KJ, Barnabas RV, Barouch DH, Cohen MS, Hurt CB, Burwen DR, Marovich MA, Musser BJ, et al. Efficacy and safety of a single dose of casirivimab and imdevimab for the prevention of COVID-19 over an 8-month period: a randomised, double-blind, placebo-controlled trial. The Lancet. Infectious Diseases. PMID 35803290 DOI: 10.1016/S1473-3099(22)00416-9  0.327
2022 Figueiredo JC, Hirsch FR, Kushi LH, Nembhard WN, Crawford JM, Mantis N, Finster L, Merin NM, Merchant A, Reckamp KL, Melmed GY, Braun J, McGovern D, Parekh S, Corley DA, ... ... Barouch DH, et al. Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies. Open Forum Infectious Diseases. 9: ofac171. PMID 35765315 DOI: 10.1093/ofid/ofac171  0.327
2022 Hachmann NP, Miller J, Collier AY, Ventura JD, Yu J, Rowe M, Bondzie EA, Powers O, Surve N, Hall K, Barouch DH. Neutralization Escape by SARS-CoV-2 Omicron Subvariants BA.2.12.1, BA.4, and BA.5. The New England Journal of Medicine. PMID 35731894 DOI: 10.1056/NEJMc2206576  0.554
2022 Walker-Sperling VEK, Mercado NB, Chandrashekar A, Borducchi EN, Liu J, Nkolola JP, Lewis M, Murry JP, Yang Y, Geleziunas R, Robb ML, Michael NL, Pau MG, Wegmann F, Schuitemaker H, ... ... Barouch DH, et al. Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques. Nature Communications. 13: 3463. PMID 35710819 DOI: 10.1038/s41467-022-31196-5  0.432
2022 Ventura JD, Nkolola JP, Chandrashekar A, Borducchi EN, Liu J, Mercado NB, Hope DL, Giffin VM, McMahan K, Geleziunas R, Murry JP, Yang Y, Lewis MG, Pau MG, Wegmann F, ... ... Barouch DH, et al. Therapeutic efficacy of an Ad26/MVA vaccine with SIV gp140 protein and vesatolimod in ART-suppressed rhesus macaques. Npj Vaccines. 7: 53. PMID 35585080 DOI: 10.1038/s41541-022-00477-x  0.518
2022 Piedra-Mora C, Robinson SR, Tostanoski LH, Dayao DAE, Chandrashekar A, Bauer K, Wrijil L, Ducat S, Hayes T, Yu J, Bondzie EA, McMahan K, Sellers D, Giffin V, Hope D, ... ... Barouch DH, et al. Reduced SARS-CoV-2 disease outcomes in Syrian hamsters receiving immune sera: Quantitative image analysis in pathologic assessments. Veterinary Pathology. 3009858221095794. PMID 35521761 DOI: 10.1177/03009858221095794  0.624
2022 Zhu DY, Gorman MJ, Yuan D, Yu J, Mercado NB, McMahan K, Borducchi EN, Lifton M, Liu J, Nampanya F, Patel S, Peter L, Tostanoski LH, Pessaint L, Van Ry A, ... ... Barouch DH, et al. Defining the determinants of protection against SARS-CoV-2 infection and viral control in a dose-down Ad26.CoV2.S vaccine study in nonhuman primates. Plos Biology. 20: e3001609. PMID 35512013 DOI: 10.1371/journal.pbio.3001609  0.754
2022 Chandrashekar A, Yu J, McMahan K, Jacob-Dolan C, Liu J, He X, Hope D, Anioke T, Barrett J, Chung B, Hachmann NP, Lifton M, Miller J, Powers O, Sciacca M, ... ... Barouch DH, et al. Vaccine protection against the SARS-CoV-2 Omicron variant in macaques. Cell. PMID 35427477 DOI: 10.1016/j.cell.2022.03.024  0.78
2022 Aid M, Vidal SJ, Piedra-Mora C, Ducat S, Chan CN, Bondoc S, Colarusso A, Starke CE, Nekorchuk M, Busman-Sahay K, Estes JD, Martinot AJ, Barouch DH. Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques. Plos Pathogens. 18: e1009990. PMID 35395058 DOI: 10.1371/journal.ppat.1009990  0.529
2022 DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, Alisoltani A, Alter G, Amara RR, Baric RS, Barouch DH, Bloom JD, Bloyet LM, Bonenfant G, Boon ACM, Boritz EA, et al. Defining the risk of SARS-CoV-2 variants on immune protection. Nature. PMID 35361968 DOI: 10.1038/s41586-022-04690-5  0.448
2022 Kaplonek P, Cizmeci D, Fischinger S, Collier AR, Suscovich T, Linde C, Broge T, Mann C, Amanat F, Dayal D, Rhee J, de St Aubin M, Nilles EJ, Musk ER, Menon AS, ... ... Barouch DH, et al. mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions. Science Translational Medicine. eabm2311. PMID 35348368 DOI: 10.1126/scitranslmed.abm2311  0.535
2022 Bekker LG, Garrett N, Goga A, Fairall L, Reddy T, Yende-Zuma N, Kassanjee R, Collie S, Sanne I, Boulle A, Seocharan I, Engelbrecht I, Davies MA, Champion J, Chen T, ... ... Barouch D, et al. Effectiveness of the Ad26.COV2.S vaccine in health-care workers in South Africa (the Sisonke study): results from a single-arm, open-label, phase 3B, implementation study. Lancet (London, England). 399: 1141-1153. PMID 35305740 DOI: 10.1016/S0140-6736(22)00007-1  0.322
2022 Yu J, Collier AY, Rowe M, Mardas F, Ventura JD, Wan H, Miller J, Powers O, Chung B, Siamatu M, Hachmann NP, Surve N, Nampanya F, Chandrashekar A, Barouch DH. Neutralization of the SARS-CoV-2 Omicron BA.1 and BA.2 Variants. The New England Journal of Medicine. PMID 35294809 DOI: 10.1056/NEJMc2201849  0.559
2022 Dalvie NC, Tostanoski LH, Rodriguez-Aponte SA, Kaur K, Bajoria S, Kumru OS, Martinot AJ, Chandrashekar A, McMahan K, Mercado NB, Yu J, Chang A, Giffin VM, Nampanya F, Patel S, ... ... Barouch DH, et al. SARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaques. Science Advances. 8: eabl6015. PMID 35294244 DOI: 10.1126/sciadv.abl6015  0.758
2022 Collier AY, Brown CM, McMahan KA, Yu J, Liu J, Jacob-Dolan C, Chandrashekar A, Tierney D, Ansel JL, Rowe M, Sellers D, Ahmad K, Aguayo R, Anioke T, Gardner S, ... ... Barouch DH, et al. Characterization of immune responses in fully vaccinated individuals following breakthrough infection with the SARS-CoV-2 delta variant. Science Translational Medicine. eabn6150. PMID 35258323 DOI: 10.1126/scitranslmed.abn6150  0.772
2022 Mahrokhian SH, Tostanoski LH, Jacob-Dolan C, Zahn RC, Wegmann F, McMahan K, Yu J, Gebre MS, Bondzie EA, Wan H, Powers O, Ye T, Barrett J, Schuitemaker H, Barouch DH. Durability and expansion of neutralizing antibody breadth following Ad26.COV2.S vaccination of mice. Npj Vaccines. 7: 23. PMID 35197477 DOI: 10.1038/s41541-022-00454-4  0.723
2022 He X, Aid M, Chandrashekar A, Yu J, McMahan K, Wegmann F, Jacob-Dolan C, Maron JS, Atyeo C, Wan H, Sellers D, Liu J, Lifton M, Gardner S, A Bondzie E, ... ... Barouch DH, et al. A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2-specific immune responses in rhesus macaques. Science Translational Medicine. eabm4996. PMID 35191769 DOI: 10.1126/scitranslmed.abm4996  0.695
2022 Yu J, Collier AY, Rowe M, Mardas F, Ventura JD, Wan H, Miller J, Powers O, Chung B, Siamatu M, Hachmann NP, Surve N, Nampanya F, Chandrashekar A, Barouch DH. Comparable Neutralization of the SARS-CoV-2 Omicron BA.1 and BA.2 Variants. Medrxiv : the Preprint Server For Health Sciences. PMID 35169817 DOI: 10.1101/2022.02.06.22270533  0.738
2022 Chandrashekar A, Yu J, McMahan K, Jacob-Dolan C, Liu J, He X, Hope D, Anioke T, Barrett J, Chung B, Hachmann NP, Lifton M, Miller J, Powers O, Sciacca M, ... ... Barouch DH, et al. Vaccine Protection Against the SARS-CoV-2 Omicron Variant in Macaques. Biorxiv : the Preprint Server For Biology. PMID 35169798 DOI: 10.1101/2022.02.06.479285  0.747
2022 Kalinke U, Barouch DH, Rizzi R, Lagkadinou E, Türeci Ö, Pather S, Neels P. Clinical development and approval of COVID-19 vaccines. Expert Review of Vaccines. 21: 609-619. PMID 35157542 DOI: 10.1080/14760584.2022.2042257  0.463
2022 Cobb RR, Nkolola J, Gilchuk P, Chandrashekar A, Yu J, House RV, Earnhart CG, Dorsey NM, Hopkins SA, Snow DM, Chen RE, VanBlargan LA, Hechenblaickner M, Hoppe B, Collins L, ... ... Barouch DH, et al. A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques. Med (New York, N.Y.). PMID 35132398 DOI: 10.1016/j.medj.2022.01.004  0.624
2022 Liu J, Chandrashekar A, Sellers D, Barrett J, Jacob-Dolan C, Lifton M, McMahan K, Sciacca M, VanWyk H, Wu C, Yu J, Collier AY, Barouch DH. Vaccines Elicit Highly Conserved Cellular Immunity to SARS-CoV-2 Omicron. Nature. PMID 35102312 DOI: 10.1038/s41586-022-04465-y  0.744
2022 Siddiqui SM, Bowman KA, Zhu AL, Fischinger S, Beger S, Maron JS, Bartsch YC, Atyeo C, Gorman MJ, Yanis A, Hultquist JF, Lorenzo-Redondo R, Ozer EA, Simons LM, Talj R, ... ... Barouch DH, et al. Serological Markers of SARS-CoV-2 Reinfection. Mbio. e0214121. PMID 35073738 DOI: 10.1128/mbio.02141-21  0.533
2022 Muñoz-Fontela C, Widerspick L, Albrecht RA, Beer M, Carroll MW, de Wit E, Diamond MS, Dowling WE, Funnell SGP, García-Sastre A, Gerhards NM, de Jong R, Munster VJ, Neyts J, Perlman S, ... ... Barouch DH, et al. Advances and gaps in SARS-CoV-2 infection models. Plos Pathogens. 18: e1010161. PMID 35025969 DOI: 10.1371/journal.ppat.1010161  0.345
2022 Liu J, Chandrashekar A, Sellers D, Barrett J, Lifton M, McMahan K, Sciacca M, VanWyk H, Wu C, Yu J, Collier AY, Barouch DH. Vaccines Elicit Highly Cross-Reactive Cellular Immunity to the SARS-CoV-2 Omicron Variant. Medrxiv : the Preprint Server For Health Sciences. PMID 35018387 DOI: 10.1101/2022.01.02.22268634  0.756
2022 Tostanoski LH, Chandrashekar A, Patel S, Yu J, Jacob-Dolan C, Chang A, Powers OC, Sellers D, Gardner S, Barrett J, Sanborn O, Stephenson KE, Ansel JL, Jaegle K, Seaman MS, ... ... Barouch DH, et al. Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters. Npj Vaccines. 7: 2. PMID 35013325 DOI: 10.1038/s41541-021-00427-z  0.735
2022 Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Cavazzoni CB, Brook B, Barman S, Chen J, Diray-Arce J, Doss-Gollin S, De Leon M, ... ... Barouch DH, et al. An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice. Science Translational Medicine. 14: eabj5305. PMID 34783582 DOI: 10.1126/scitranslmed.abj5305  0.674
2021 Rodrigues KA, Rodriguez-Aponte SA, Dalvie NC, Lee JH, Abraham W, Carnathan DG, Jimenez LE, Ngo JT, Chang JYH, Zhang Z, Yu J, Chang A, Nakao C, Goodwin B, Naranjo CA, ... ... Barouch DH, et al. Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2. Science Advances. 7: eabj6538. PMID 34878851 DOI: 10.1126/sciadv.abj6538  0.649
2021 Nilles EJ, Siddiqui SM, Fischinger S, Bartsch YC, de St Aubin M, Zhou G, Gluck MJ, Berger S, Rhee J, Petersen E, Mormann B, Loesche M, Hu Y, Chen Z, Yu J, ... ... Barouch DH, et al. Epidemiological and Immunological Features of Obesity and SARS-CoV-2. Viruses. 13. PMID 34835041 DOI: 10.3390/v13112235  0.6
2021 Gebre MS, Rauch S, Roth N, Yu J, Chandrashekar A, Mercado NB, He X, Liu J, McMahan K, Martinot A, Martinez DR, Giffin T, Hope D, Patel S, Sellers D, ... ... Barouch DH, et al. Optimization of Non-Coding Regions for a Non-Modified mRNA COVID-19 Vaccine. Nature. PMID 34794169 DOI: 10.1038/s41586-021-04231-6  0.744
2021 Collier AY, Yu J, Mcmahan K, Liu J, Atyeo C, Ansel JL, Fricker ZP, Pavlakis M, Curry MP, Jacob-Dolan C, Patel H, Sellers D, Barrett J, Rowe M, Ahmad K, ... ... Barouch DH, et al. COVID-19 mRNA Vaccine Immunogenicity in Immunosuppressed Individuals. The Journal of Infectious Diseases. PMID 34792136 DOI: 10.1093/infdis/jiab569  0.735
2021 Iketani S, Liu L, Nair MS, Chandrashekar A, Mohri H, Wang M, Barouch DH, Huang Y, Ho DD. Ad26.COV2.S boosts antibody and T-cell responses following BNT162b2 vaccination. Emerging Microbes & Infections. 1-9. PMID 34779713 DOI: 10.1080/22221751.2021.2006581  0.468
2021 Gebre MS, Rauch S, Roth N, Gergen J, Yu J, Liu X, Cole AC, Mueller SO, Petsch B, Barouch DH. mRNA Vaccines Induce Rapid Antibody Responses in Mice. Biorxiv : the Preprint Server For Biology. PMID 34751269 DOI: 10.1101/2021.11.01.466863  0.746
2021 Yu J, Collins ND, Mercado NB, McMahan K, Chandrashekar A, Liu J, Anioke T, Chang A, Giffin VM, Hope DL, Sellers D, Nampanya F, Gardner S, Barrett J, Wan H, ... ... Barouch DH, et al. Protective Efficacy of Gastrointestinal SARS-CoV-2 Delivery Against Intranasal and Intratracheal SARS-CoV-2 Challenge in Rhesus Macaques. Journal of Virology. JVI0159921. PMID 34705557 DOI: 10.1128/JVI.01599-21  0.747
2021 Tostanoski LH, Yu J, Mercado NB, McMahan K, Jacob-Dolan C, Martinot AJ, Piedra-Mora C, Anioke T, Chang A, Giffin VM, Hope DL, Wan H, Bondzie EA, Mahrokhian SH, Wrijil LM, ... ... Barouch DH, et al. Immunity elicited by natural infection or Ad26.COV2.S vaccination protects hamsters against SARS-CoV-2 variants of concern. Science Translational Medicine. eabj3789. PMID 34705477 DOI: 10.1126/scitranslmed.abj3789  0.743
2021 Collier AY, Brown CM, Mcmahan K, Yu J, Liu J, Jacob-Dolan C, Chandrashekar A, Tierney D, Ansel JL, Rowe M, Sellers D, Ahmad K, Aguayo R, Anioke T, Gardner S, ... ... Barouch DH, et al. Immune Responses in Fully Vaccinated Individuals Following Breakthrough Infection with the SARS-CoV-2 Delta Variant in Provincetown, Massachusetts. Medrxiv : the Preprint Server For Health Sciences. PMID 34704104 DOI: 10.1101/2021.10.18.21265113  0.733
2021 Collier AY, Yu J, McMahan K, Liu J, Chandrashekar A, Maron JS, Atyeo C, Martinez DR, Ansel JL, Aguayo R, Rowe M, Jacob-Dolan C, Sellers D, Barrett J, Ahmad K, ... ... Barouch DH, et al. Differential Kinetics of Immune Responses Elicited by Covid-19 Vaccines. The New England Journal of Medicine. PMID 34648703 DOI: 10.1056/NEJMc2115596  0.731
2021 Roozendaal R, Solforosi L, Stieh DJ, Serroyen J, Straetemans R, Dari A, Boulton M, Wegmann F, Rosendahl Huber SK, van der Lubbe JEM, Hendriks J, Le Gars M, Dekking L, Czapska-Casey DN, Guimera N, ... ... Barouch DH, et al. SARS-CoV-2 binding and neutralizing antibody levels after Ad26.COV2.S vaccination predict durable protection in rhesus macaques. Nature Communications. 12: 5877. PMID 34620860 DOI: 10.1038/s41467-021-26117-x  0.756
2021 Jacob-Dolan C, Barouch DH. COVID-19 Vaccines: Adenoviral Vectors. Annual Review of Medicine. 73: 41-54. PMID 34609905 DOI: 10.1146/annurev-med-012621-102252  0.495
2021 Langellotto F, Dellacherie MO, Yeager C, Ijaz H, Yu J, Cheng CA, Dimitrakakis N, Seiler BT, Gebre MS, Gilboa T, Johnson R, Storm N, Bardales S, Graveline A, White D, ... ... Barouch DH, et al. A Modular Biomaterial Scaffold-Based Vaccine Elicits Durable Adaptive Immunity to Subunit SARS-CoV-2 Antigens. Advanced Healthcare Materials. e2101370. PMID 34605223 DOI: 10.1002/adhm.202101370  0.766
2021 Chandrashekar A, Liu J, Yu J, McMahan K, Tostanoski LH, Jacob-Dolan C, Mercado NB, Anioke T, Chang A, Gardner S, Giffin VM, Hope DL, Nampanya F, Patel S, Sanborn O, ... ... Barouch DH, et al. Prior infection with SARS-CoV-2 WA1/2020 partially protects rhesus macaques against re-infection with B.1.1.7 and B.1.351 variants. Science Translational Medicine. eabj2641. PMID 34546094 DOI: 10.1126/scitranslmed.abj2641  0.575
2021 Tostanoski LH, Gralinski LE, Martinez DR, Schaefer A, Mahrokhian SH, Li Z, Nampanya F, Wan H, Yu J, Chang A, Liu J, McMahan K, Ventura JD, Dinnon KH, Leist SR, ... ... Barouch DH, et al. Protective efficacy of rhesus adenovirus COVID-19 vaccines against mouse-adapted SARS-CoV-2. Journal of Virology. JVI0097421. PMID 34523968 DOI: 10.1128/JVI.00974-21  0.772
2021 Kaplonek P, Cizmeci D, Fischinger S, Collier AR, Suscovich T, Linde C, Broge T, Mann C, Amanat F, Dayal D, Rhee J, de St Aubin M, Nilles EJ, Musk ER, Menon AS, ... ... Barouch DH, et al. Subtle immunological differences in mRNA-1273 and BNT162b2 COVID-19 vaccine induced Fc-functional profiles. Biorxiv : the Preprint Server For Biology. PMID 34494026 DOI: 10.1101/2021.08.31.458247  0.531
2021 Dalvie NC, Rodriguez-Aponte SA, Hartwell BL, Tostanoski LH, Biedermann AM, Crowell LE, Kaur K, Kumru OS, Carter L, Yu J, Chang A, McMahan K, Courant T, Lebas C, Lemnios AA, ... ... Barouch DH, et al. Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34493582 DOI: 10.1073/pnas.2106845118  0.715
2021 Sivapalan R, Liu J, Chakraborty K, Arthofer E, Choudhry M, Barie PS, Barouch DH, Henley T. Virus Induced Lymphocytes (VIL) as a novel viral antigen-specific T cell therapy for COVID-19 and potential future pandemics. Scientific Reports. 11: 15295. PMID 34315945 DOI: 10.1038/s41598-021-94654-y  0.325
2021 Dalvie NC, Tostanoski LH, Rodriguez-Aponte SA, Kaur K, Bajoria S, Kumru OS, Martinot AJ, Chandrashekar A, McMahan K, Mercado NB, Yu J, Chang A, Giffin VM, Nampanya F, Patel S, ... ... Barouch DH, et al. A modular protein subunit vaccine candidate produced in yeast confers protection against SARS-CoV-2 in non-human primates. Biorxiv : the Preprint Server For Biology. PMID 34282417 DOI: 10.1101/2021.07.13.452251  0.75
2021 Najafabadi AH, Abadi ZIN, Aikins ME, Foulds KE, Donaldson MM, Yuan W, Okeke EB, Nam J, Xu Y, Weerappuli P, Hetrick T, Adams D, Lester PA, Salazar AM, Barouch DH, et al. Vaccine nanodiscs plus polyICLC elicit robust CD8+ T cell responses in mice and non-human primates. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 34280415 DOI: 10.1016/j.jconrel.2021.07.026  0.444
2021 Barouch DH, Stephenson KE, Sadoff J, Yu J, Chang A, Gebre M, McMahan K, Liu J, Chandrashekar A, Patel S, Gars ML, de Groot AM, Heerwegh D, Struyf F, Douoguih M, et al. Durable Humoral and Cellular Immune Responses Following Ad26.COV2.S Vaccination for COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 34268527 DOI: 10.1101/2021.07.05.21259918  0.727
2021 Barouch DH, Stephenson KE, Sadoff J, Yu J, Chang A, Gebre M, McMahan K, Liu J, Chandrashekar A, Patel S, Le Gars M, de Groot AM, Heerwegh D, Struyf F, Douoguih M, et al. Durable Humoral and Cellular Immune Responses 8 Months after Ad26.COV2.S Vaccination. The New England Journal of Medicine. PMID 34260834 DOI: 10.1056/NEJMc2108829  0.732
2021 Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Gallagher KME, Bauer MR, Taylor HB, Dunn WA, Tarr C, Sidney J, Rachimi S, Conway HL, Katsis K, Wang Y, ... ... Barouch DH, et al. Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs. Cell. PMID 34171305 DOI: 10.1016/j.cell.2021.05.046  0.367
2021 Larocca RA, Abbink P, Ventura JD, Chandrashekar A, Mercado N, Li Z, Borducchi E, De La Barrera RA, Eckels KH, Modjarrad K, Busch MP, Michael NL, Barouch DH. Impact of prior Dengue immunity on Zika vaccine protection in rhesus macaques and mice. Plos Pathogens. 17: e1009673. PMID 34170962 DOI: 10.1371/journal.ppat.1009673  0.549
2021 Yu J, Tostanoski LH, Mercado NB, McMahan K, Liu J, Jacob-Dolan C, Chandrashekar A, Atyeo C, Martinez DR, Anioke T, Bondzie EA, Chang A, Gardner S, Giffin VM, Hope DL, ... ... Barouch DH, et al. Protective efficacy of Ad26.COV2.S against SARS-CoV-2 B.1.351 in macaques. Nature. PMID 34161961 DOI: 10.1038/s41586-021-03732-8  0.716
2021 Tostanoski LH, Gralinski LE, Martinez DR, Schaefer A, Mahrokhian SH, Li Z, Nampanya F, Wan H, Yu J, Chang A, Liu J, McMahan K, Dinnon KH, Leist SR, Baric RS, ... Barouch DH, et al. Protective efficacy of rhesus adenovirus COVID-19 vaccines against mouse-adapted SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 34159335 DOI: 10.1101/2021.06.14.448461  0.766
2021 He X, Chandrashekar A, Zahn R, Wegmann F, Yu J, Mercado NB, McMahan K, Martinot AJ, Piedra-Mora C, Beecy S, Ducat S, Chamanza R, Huber SR, van Heerden M, van der Fits L, ... ... Barouch DH, et al. Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques. Cell. PMID 34133941 DOI: 10.1016/j.cell.2021.05.040  0.728
2021 Alter G, Yu J, Liu J, Chandrashekar A, Borducchi EN, Tostanoski LH, McMahan K, Jacob-Dolan C, Martinez DR, Chang A, Anioke T, Lifton M, Nkolola J, Stephenson KE, Atyeo C, ... ... Barouch DH, et al. Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans. Nature. PMID 34107529 DOI: 10.1038/s41586-021-03681-2  0.729
2021 Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Brook B, Chen J, Diray-Arce J, Doss-Gollin S, Leon M, Chew K, Menon M, ... ... Barouch DH, et al. Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity. Biorxiv : the Preprint Server For Biology. PMID 34031655 DOI: 10.1101/2021.05.20.444848  0.723
2021 Collier AY, McMahan K, Yu J, Tostanoski LH, Aguayo R, Ansel J, Chandrashekar A, Patel S, Apraku Bondzie E, Sellers D, Barrett J, Sanborn O, Wan H, Chang A, Anioke T, ... ... Barouch DH, et al. Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women. Jama. PMID 33983379 DOI: 10.1001/jama.2021.7563  0.685
2021 Solforosi L, Kuipers H, Jongeneelen M, Rosendahl Huber SK, van der Lubbe JEM, Dekking L, Czapska-Casey DN, Izquierdo Gil A, Baert MRM, Drijver J, Vaneman J, van Huizen E, Choi Y, Vreugdenhil J, Kroos S, ... ... Barouch DH, et al. Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP. The Journal of Experimental Medicine. 218. PMID 33909009 DOI: 10.1084/jem.20202756  0.464
2021 Vidal SJ, Collier AY, Yu J, McMahan K, Tostanoski LH, Ventura JD, Aid M, Peter L, Jacob-Dolan C, Anioke T, Chang A, Wan H, Aguayo R, Ngo D, Gerszten RE, ... ... Barouch DH, et al. Correlates of Neutralization Against SARS-CoV-2 Variants of Concern by Early Pandemic Sera. Journal of Virology. PMID 33893169 DOI: 10.1128/JVI.00404-21  0.7
2021 Sadoff J, Gray G, Vandebosch A, Cárdenas V, Shukarev G, Grinsztejn B, Goepfert PA, Truyers C, Fennema H, Spiessens B, Offergeld K, Scheper G, Taylor KL, Robb ML, Treanor J, ... Barouch DH, et al. Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19. The New England Journal of Medicine. PMID 33882225 DOI: 10.1056/NEJMoa2101544  0.423
2021 van der Lubbe JEM, Rosendahl Huber SK, Vijayan A, Dekking L, van Huizen E, Vreugdenhil J, Choi Y, Baert MRM, Feddes-de Boer K, Izquierdo Gil A, van Heerden M, Dalebout TJ, Myeni SK, Kikkert M, Snijder EJ, ... ... Barouch DH, et al. Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease. Npj Vaccines. 6: 39. PMID 33741993 DOI: 10.1038/s41541-021-00301-y  0.532
2021 Gebre MS, Brito LA, Tostanoski LH, Edwards DK, Carfi A, Barouch DH. Novel approaches for vaccine development. Cell. 184: 1589-1603. PMID 33740454 DOI: 10.1016/j.cell.2021.02.030  0.484
2021 Yu J, Li Z, He X, Gebre MS, Bondzie EA, Wan H, Jacob-Dolan C, Martinez DR, Nkolola JP, Baric RS, Barouch DH. Deletion of the SARS-CoV-2 Spike Cytoplasmic Tail Increases Infectivity in Pseudovirus Neutralization Assays. Journal of Virology. PMID 33727331 DOI: 10.1128/JVI.00044-21  0.726
2021 Stephenson KE, Le Gars M, Sadoff J, de Groot AM, Heerwegh D, Truyers C, Atyeo C, Loos C, Chandrashekar A, McMahan K, Tostanoski LH, Yu J, Gebre MS, Jacob-Dolan C, Li Z, ... ... Barouch DH, et al. Immunogenicity of the Ad26.COV2.S Vaccine for COVID-19. Jama. PMID 33704352 DOI: 10.1001/jama.2021.3645  0.727
2021 Jacob-Dolan C, Feldman J, McMahan K, Yu J, Zahn R, Wegmann F, Schuitemaker H, Schmidt AG, Barouch DH. Coronavirus-Specific Antibody Cross Reactivity in Rhesus Macaques Following SARS-CoV-2 Vaccination and Infection. Journal of Virology. PMID 33692201 DOI: 10.1128/JVI.00117-21  0.766
2021 Dalvie NC, Rodriguez-Aponte SA, Hartwell BL, Tostanoski LH, Biedermann AM, Crowell LE, Kaur K, Kumru O, Carter L, Yu J, Chang A, McMahan K, Courant T, Lebas C, Lemnios AA, ... ... Barouch DH, et al. Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters. Biorxiv : the Preprint Server For Biology. PMID 33688647 DOI: 10.1101/2021.03.03.433558  0.726
2021 Yu KK, Fischinger S, Smith MT, Atyeo C, Cizmeci D, Wolf CR, Layton ED, Logue JK, Aguilar MS, Shuey K, Loos C, Yu J, Franko NM, Choi RY, Wald A, ... Barouch DH, et al. Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2. Jci Insight. PMID 33621211 DOI: 10.1172/jci.insight.146242  0.613
2021 Bartsch YC, Fischinger S, Siddiqui SM, Chen Z, Yu J, Gebre M, Atyeo C, Gorman MJ, Zhu AL, Kang J, Burke JS, Slein M, Gluck MJ, Beger S, Hu Y, ... ... Barouch DH, et al. Discrete SARS-CoV-2 antibody titers track with functional humoral stability. Nature Communications. 12: 1018. PMID 33589636 DOI: 10.1038/s41467-021-21336-8  0.703
2021 Salisch NC, Stephenson KE, Williams K, Cox F, van der Fits L, Heerwegh D, Truyers C, Habets MN, Kanjilal DG, Larocca RA, Abbink P, Liu J, Peter L, Fierro C, De La Barrera RA, ... ... Barouch DH, et al. A Double-Blind, Randomized, Placebo-Controlled Phase 1 Study of Ad26.ZIKV.001, an Ad26-Vectored Anti-Zika Virus Vaccine. Annals of Internal Medicine. PMID 33587687 DOI: 10.7326/M20-5306  0.443
2021 He X, Chandrashekar A, Zahn R, Wegmann F, Yu J, Mercado NB, McMahan K, Martinot AJ, Piedra-Mora C, Beecy S, Ducat S, Chamanza R, Huber SR, van der Fits L, Borducchi EN, ... ... Barouch DH, et al. Low-Dose Ad26.COV2.S Protection Against SARS-CoV-2 Challenge in Rhesus Macaques. Biorxiv : the Preprint Server For Biology. PMID 33532782 DOI: 10.1101/2021.01.27.428380  0.73
2021 Murakowski DK, Barton JP, Peter L, Chandrashekar A, Bondzie E, Gao A, Barouch DH, Chakraborty AK. Adenovirus-vectored vaccine containing multidimensionally conserved parts of the HIV proteome is immunogenic in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33514660 DOI: 10.1073/pnas.2022496118  0.469
2021 Hu Z, Leet DE, Allesøe RL, Oliveira G, Li S, Luoma AM, Liu J, Forman J, Huang T, Iorgulescu JB, Holden R, Sarkizova S, Gohil SH, Redd RA, Sun J, ... ... Barouch DH, et al. Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma. Nature Medicine. PMID 33479501 DOI: 10.1038/s41591-020-01206-4  0.432
2021 Mercado NB, Zahn R, Wegmann F, Loos C, Chandrashekar A, Yu J, Liu J, Peter L, McMahan K, Tostanoski LH, He X, Martinez DR, Rutten L, Bos R, van Manen D, ... ... Barouch DH, et al. Publisher Correction: Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques. Nature. PMID 33469218 DOI: 10.1038/s41586-020-03100-y  0.72
2021 Sadoff J, Le Gars M, Shukarev G, Heerwegh D, Truyers C, de Groot AM, Stoop J, Tete S, Van Damme W, Leroux-Roels I, Berghmans PJ, Kimmel M, Van Damme P, de Hoon J, Smith W, ... ... Barouch DH, et al. Interim Results of a Phase 1-2a Trial of Ad26.COV2.S Covid-19 Vaccine. The New England Journal of Medicine. PMID 33440088 DOI: 10.1056/NEJMoa2034201  0.454
2020 Martinot AJ, Blass E, Yu J, Aid M, Mahrokhian SH, Cohen SB, Plumlee CR, Larocca RA, Siddiqi N, Wakabayashi S, Gardner M, Audette R, Devorak A, Urdahl KB, Rubin EJ, ... Barouch DH, et al. Protective efficacy of an attenuated Mtb ΔLprG vaccine in mice. Plos Pathogens. 16: e1009096. PMID 33315936 DOI: 10.1371/journal.ppat.1009096  0.726
2020 McMahan K, Yu J, Mercado NB, Loos C, Tostanoski LH, Chandrashekar A, Liu J, Peter L, Atyeo C, Zhu A, Bondzie EA, Dagotto G, Gebre MS, Jacob-Dolan C, Li Z, ... ... Barouch DH, et al. Correlates of protection against SARS-CoV-2 in rhesus macaques. Nature. PMID 33276369 DOI: 10.1038/s41586-020-03041-6  0.745
2020 Yu KKQ, Fischinger S, Smith MT, Atyeo C, Cizmeci D, Wolf CR, Layton ED, Logue JK, Aguilar MS, Shuey K, Loos C, Yu J, Franko N, Choi RY, Wald A, ... Barouch DH, et al. T cell and antibody functional correlates of severe COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 33269369 DOI: 10.1101/2020.11.25.20235150  0.643
2020 Mahomed S, Garrett N, Karim QA, Zuma NY, Capparelli E, Baxter C, Gengiah T, Archary D, Samsunder N, Rose ND, Moore P, Williamson C, Barouch DH, Fast PE, Pozzetto B, et al. Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial. Bmj Open. 10: e042247. PMID 33243815 DOI: 10.1136/bmjopen-2020-042247  0.306
2020 Zohar T, Loos C, Fischinger S, Atyeo C, Wang C, Slein MD, Burke J, Yu J, Feldman J, Hauser BM, Caradonna T, Schmidt AG, Cai Y, Streeck H, Ryan ET, ... Barouch DH, et al. Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality. Cell. PMID 33207184 DOI: 10.1016/j.cell.2020.10.052  0.7
2020 Nilles EJ, Siddiqui SM, Fischinger S, Bartsch YC, de Saint Aubin M, Zhou G, Gluck M, Berger S, Rhee J, Petersen E, Mormann B, Loesche M, Chen Z, Yu J, Gebre M, ... ... Barouch DH, et al. Epidemiological and immunological features of obesity and SARS-CoV-2. Medrxiv : the Preprint Server For Health Sciences. PMID 33200139 DOI: 10.1101/2020.11.11.20229724  0.557
2020 Bricker KM, Obregon-Perko V, Uddin F, Williams B, Uffman EA, Garrido C, Fouda GG, Geleziunas R, Robb M, Michael N, Barouch DH, Chahroudi A. Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation. Plos Pathogens. 16: e1008954. PMID 33104758 DOI: 10.1371/journal.ppat.1008954  0.482
2020 Bos R, Rutten L, van der Lubbe JEM, Bakkers MJG, Hardenberg G, Wegmann F, Zuijdgeest D, de Wilde AH, Koornneef A, Verwilligen A, van Manen D, Kwaks T, Vogels R, Dalebout TJ, Myeni SK, ... ... Barouch DH, et al. Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses. Npj Vaccines. 5: 91. PMID 33083026 DOI: 10.1038/s41541-020-00243-x  0.452
2020 Iyer AS, Jones FK, Nodoushani A, Kelly M, Becker M, Slater D, Mills R, Teng E, Kamruzzaman M, Garcia-Beltran WF, Astudillo M, Yang D, Miller TE, Oliver E, Fischinger S, ... ... Barouch DH, et al. Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients. Science Immunology. 5. PMID 33033172 DOI: 10.1126/sciimmunol.abe0367  0.619
2020 Baden LR, Stieh DJ, Sarnecki M, Walsh SR, Tomaras GD, Kublin JG, McElrath MJ, Alter G, Ferrari G, Montefiori D, Mann P, Nijs S, Callewaert K, Goepfert P, Edupuganti S, ... ... Barouch DH, et al. Safety and immunogenicity of two heterologous HIV vaccine regimens in healthy, HIV-uninfected adults (TRAVERSE): a randomised, parallel-group, placebo-controlled, double-blind, phase 1/2a study. The Lancet. Hiv. 7: e688-e698. PMID 33010242 DOI: 10.1016/S2352-3018(20)30229-0  0.414
2020 Alter G, Yu WH, Chandrashekar A, Borducchi EN, Ghneim K, Sharma A, Nedellec R, McKenney KR, Linde C, Broge T, Suscovich TJ, Linnekin T, Abbink P, Mercado NB, Nkolola JP, ... ... Barouch DH, et al. Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques. Cell. 183: 185-196.e14. PMID 33007262 DOI: 10.1016/j.cell.2020.08.033  0.543
2020 Muñoz-Fontela C, Dowling WE, Funnell SGP, Gsell PS, Balta XR, Albrecht RA, Andersen H, Baric RS, Carroll MW, Cavaleri M, Qin C, Crozier I, Dallmeier K, de Waal L, de Wit E, ... ... Barouch DH, et al. Animal models for COVID-19. Nature. PMID 32967005 DOI: 10.1038/s41586-020-2787-6  0.437
2020 Tostanoski LH, Wegmann F, Martinot AJ, Loos C, McMahan K, Mercado NB, Yu J, Chan CN, Bondoc S, Starke CE, Nekorchuk M, Busman-Sahay K, Piedra-Mora C, Wrijil LM, Ducat S, ... ... Barouch DH, et al. Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters. Nature Medicine. PMID 32884153 DOI: 10.1038/S41591-020-1070-6  0.738
2020 Dagotto G, Yu J, Barouch DH. Approaches and Challenges in SARS-CoV-2 Vaccine Development. Cell Host & Microbe. PMID 32798444 DOI: 10.1016/j.chom.2020.08.002  0.746
2020 Atyeo C, Fischinger S, Zohar T, Slein MD, Burke J, Loos C, McCulloch DJ, Newman KL, Wolf C, Yu J, Shuey K, Feldman J, Hauser BM, Caradonna T, Schmidt AG, ... ... Barouch D, et al. Distinct Early Serological Signatures Track with SARS-CoV-2 Survival. Immunity. PMID 32783920 DOI: 10.1016/J.Immuni.2020.07.020  0.673
2020 Iyer AS, Jones FK, Nodoushani A, Kelly M, Becker M, Slater D, Mills R, Teng E, Kamruzzaman M, Garcia-Beltran WF, Astudillo M, Yang D, Miller TE, Oliver E, Fischinger S, ... ... Barouch DH, et al. Dynamics and significance of the antibody response to SARS-CoV-2 infection. Medrxiv : the Preprint Server For Health Sciences. PMID 32743600 DOI: 10.1101/2020.07.18.20155374  0.637
2020 Mercado NB, Zahn R, Wegmann F, Loos C, Chandrashekar A, Yu J, Liu J, Peter L, McMahan K, Tostanoski LH, He X, Martinez DR, Rutten L, Bos R, van Manen D, ... ... Barouch DH, et al. Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques. Nature. PMID 32731257 DOI: 10.1038/S41586-020-2607-Z  0.761
2020 Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, ... ... Barouch DH, et al. Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. PMID 32668443 DOI: 10.1038/S41586-020-2548-6  0.375
2020 Stephenson KE, Tan CS, Walsh SR, Hale A, Ansel JL, Kanjilal DG, Jaegle K, Peter L, Borducchi EN, Nkolola JP, Makoni T, Fogel R, Bradshaw C, Tyler A, Moseley E, ... ... Barouch DH, et al. Safety and immunogenicity of a Zika purified inactivated virus vaccine given via standard, accelerated, or shortened schedules: a single-centre, double-blind, sequential-group, randomised, placebo-controlled, phase 1 trial. The Lancet. Infectious Diseases. PMID 32618279 DOI: 10.1016/S1473-3099(20)30085-2  0.484
2020 López-Camacho C, De Lorenzo G, Slon-Campos JL, Dowall S, Abbink P, Larocca RA, Kim YC, Poggianella M, Graham V, Findlay-Wilson S, Rayner E, Carmichael J, Dejnirattisai W, Boyd M, Hewson R, ... ... Barouch DH, et al. Immunogenicity and Efficacy of Zika Virus Envelope Domain III in DNA, Protein, and ChAdOx1 Adenoviral-Vectored Vaccines. Vaccines. 8. PMID 32560145 DOI: 10.3390/vaccines8020307  0.562
2020 Chandrashekar A, Liu J, Martinot AJ, McMahan K, Mercado NB, Peter L, Tostanoski LH, Yu J, Maliga Z, Nekorchuk M, Busman-Sahay K, Terry M, Wrijil LM, Ducat S, Martinez DR, ... ... Barouch DH, et al. SARS-CoV-2 infection protects against rechallenge in rhesus macaques. Science (New York, N.Y.). PMID 32434946 DOI: 10.1126/Science.Abc4776  0.695
2020 Yu J, Tostanoski LH, Peter L, Mercado NB, McMahan K, Mahrokhian SH, Nkolola JP, Liu J, Li Z, Chandrashekar A, Martinez DR, Loos C, Atyeo C, Fischinger S, Burke JS, ... ... Barouch DH, et al. DNA vaccine protection against SARS-CoV-2 in rhesus macaques. Science (New York, N.Y.). PMID 32434945 DOI: 10.1126/Science.Abc6284  0.776
2020 Stephenson KE, Wagh K, Korber B, Barouch DH. Vaccines and Broadly Neutralizing Antibodies for HIV-1 Prevention. Annual Review of Immunology. 38: 673-703. PMID 32340576 DOI: 10.1146/Annurev-Immunol-080219-023629  0.343
2020 Colby DJ, Sarnecki M, Barouch DH, Tipsuk S, Stieh DJ, Kroon E, Schuetz A, Intasan J, Sacdalan C, Pinyakorn S, Grandin P, Song H, Tovanabutra S, Shubin Z, Kim D, et al. Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption. Nature Medicine. PMID 32235883 DOI: 10.1038/s41591-020-0774-y  0.42
2020 Stephenson KE, Wegmann F, Tomaka F, Walsh SR, Tan CS, Lavreys L, Ansel JL, Kanjilal DG, Jaegle K, Nkolola JP, Peter L, Fogel R, Bradshaw C, Tyler A, Makoni T, ... ... Barouch DH, et al. Comparison of shortened mosaic HIV-1 vaccine schedules: a randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) and a preclinical study in rhesus monkeys (NHP 17-22). The Lancet. Hiv. PMID 32078815 DOI: 10.1016/S2352-3018(20)30001-1  0.402
2020 Dussupt V, Sankhala RS, Gromowski GD, Donofrio G, De La Barrera RA, Larocca RA, Zaky W, Mendez-Rivera L, Choe M, Davidson E, McCracken MK, Brien JD, Abbink P, Bai H, Bryan AL, ... ... Barouch DH, et al. Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nature Medicine. PMID 32015557 DOI: 10.1038/S41591-019-0746-2  0.57
2020 Julg B, Barouch DH. Neutralizing antibodies for HIV-1 prevention. Current Opinion in Hiv and Aids. 14: 318-324. PMID 31082819 DOI: 10.1097/COH.0000000000000556  0.322
2019 Tartaglia LJ, Badamchi-Zadeh A, Abbink P, Blass E, Aid M, Gebre MS, Li Z, Pastores KC, Trott S, Gupte S, Larocca RA, Barouch DH. Alpha-defensin 5 differentially modulates adenovirus vaccine vectors from different serotypes in vivo. Plos Pathogens. 15: e1008180. PMID 31841560 DOI: 10.1371/journal.ppat.1008180  0.37
2019 López-Camacho C, Kim YC, Abbink P, Larocca RA, Huiskonen JT, Barouch DH, Reyes-Sandoval A. Assessment of Immunogenicity and Efficacy of a Zika Vaccine Using Modified Vaccinia Ankara Virus as Carriers. Pathogens (Basel, Switzerland). 8. PMID 31684117 DOI: 10.3390/pathogens8040216  0.526
2019 Larocca RA, Mendes EA, Abbink P, Peterson RL, Martinot AJ, Iampietro MJ, Kang ZH, Aid M, Kirilova M, Jacob-Dolan C, Tostanoski L, Borducchi EN, De La Barrera RA, Barouch DH. Adenovirus Vector-Based Vaccines Confer Maternal-Fetal Protection against Zika Virus Challenge in Pregnant IFN-αβR Mice. Cell Host & Microbe. PMID 31668877 DOI: 10.1016/j.chom.2019.10.001  0.477
2019 Pegu A, Borate B, Huang Y, Pauthner MG, Hessell AJ, Julg B, Doria-Rose NA, Schmidt SD, Carpp LN, Cully MD, Chen X, Shaw GM, Barouch DH, Haigwood NL, Corey L, et al. A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge. Cell Host & Microbe. 26: 336-346.e3. PMID 31513771 DOI: 10.1016/J.Chom.2019.08.014  0.351
2019 Ehrenberg PK, Shangguan S, Issac B, Alter G, Geretz A, Izumi T, Bryant C, Eller MA, Wegmann F, Apps R, Creegan M, Bolton DL, Sekaly RP, Robb ML, Gramzinski RA, ... ... Barouch DH, et al. A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials. Science Translational Medicine. 11. PMID 31462510 DOI: 10.1126/Scitranslmed.Aaw4236  0.465
2019 Bricault CA, Yusim K, Seaman MS, Yoon H, Theiler J, Giorgi EE, Wagh K, Theiler M, Hraber P, Macke JP, Kreider EF, Learn GH, Hahn BH, Scheid JF, Kovacs JM, ... ... Barouch DH, et al. HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host & Microbe. 26: 296. PMID 31415756 DOI: 10.1016/j.chom.2019.07.016  0.388
2019 Petitdemange C, Kasturi SP, Kozlowski PA, Nabi R, Quarnstrom CF, Reddy PBJ, Derdeyn CA, Spicer LM, Patel P, Legere T, Kovalenkov YO, Labranche CC, Villinger F, Tomai M, Vasilakos J, ... ... Barouch D, et al. Vaccine induction of antibodies and tissue-resident CD8+ T cells enhances protection against mucosal SHIV-infection in young macaques. Jci Insight. 4. PMID 30830870 DOI: 10.1172/Jci.Insight.126047  0.469
2019 Jones AT, Shen X, Walter KL, LaBranche CC, Wyatt LS, Tomaras GD, Montefiori DC, Moss B, Barouch DH, Clements JD, Kozlowski PA, Varadarajan R, Amara RR. HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge. Nature Communications. 10: 798. PMID 30778066 DOI: 10.1038/S41467-019-08739-4  0.533
2019 Bricault CA, Yusim K, Seaman MS, Yoon H, Theiler J, Giorgi EE, Wagh K, Theiler M, Hraber P, Macke JP, Kreider EF, Learn GH, Hahn BH, Scheid JF, Kovacs JM, ... ... Barouch DH, et al. HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host & Microbe. 25: 59-72.e8. PMID 30629920 DOI: 10.1016/J.Chom.2018.12.001  0.492
2019 Barouch DH, Picker LJ. Novel vaccine vectors for HIV-1. Nature Reviews. Microbiology. 15: 696. PMID 29021601 DOI: 10.1038/nrmicro.2017.134  0.378
2018 Pauthner MG, Nkolola JP, Havenar-Daughton C, Murrell B, Reiss SM, Bastidas R, Prévost J, Nedellec R, von Bredow B, Abbink P, Cottrell CA, Kulp DW, Tokatlian T, Nogal B, Bianchi M, ... ... Barouch DH, et al. Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers. Immunity. PMID 30552025 DOI: 10.1016/J.Immuni.2018.11.011  0.527
2018 Stephenson KE, Keefer MC, Bunce CA, Frances D, Abbink P, Maxfield LF, Neubauer GH, Nkolola J, Peter L, Lane C, Park H, Verlinde C, Lombardo A, Yallop C, Havenga M, ... ... Barouch DH, et al. First-in-human randomized controlled trial of an oral, replicating adenovirus 26 vector vaccine for HIV-1. Plos One. 13: e0205139. PMID 30427829 DOI: 10.1371/journal.pone.0205139  0.348
2018 Badamchi-Zadeh A, Moynihan KD, Larocca RA, Aid M, Provine NM, Iampietro MJ, Kinnear E, Penaloza-MacMaster P, Abbink P, Blass E, Tregoning JS, Irvine DJ, Barouch DH. Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy. Journal of Immunology (Baltimore, Md. : 1950). 201: 2744-2752. PMID 30249811 DOI: 10.4049/Jimmunol.1800885  0.439
2018 Cox F, van der Fits L, Abbink P, Larocca RA, van Huizen E, Saeland E, Verhagen J, Peterson R, Tolboom J, Kaufmann B, Schuitemaker H, Barouch DH, Zahn R. Adenoviral vector type 26 encoding Zika virus (ZIKV) M-Env antigen induces humoral and cellular immune responses and protects mice and nonhuman primates against ZIKV challenge. Plos One. 13: e0202820. PMID 30142207 DOI: 10.1371/journal.pone.0202820  0.462
2018 Lofano G, Gorman MJ, Yousif AS, Yu WH, Fox JM, Dugast AS, Ackerman ME, Suscovich TJ, Weiner J, Barouch D, Streeck H, Little S, Smith D, Richman D, Lauffenburger D, et al. Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement. Science Immunology. 3. PMID 30120121 DOI: 10.1126/Sciimmunol.Aat7796  0.356
2018 Barouch DH, Tomaka FL, Wegmann F, Stieh DJ, Alter G, Robb ML, Michael NL, Peter L, Nkolola JP, Borducchi EN, Chandrashekar A, Jetton D, Stephenson KE, Li W, Korber B, et al. Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19). Lancet (London, England). 392: 232-243. PMID 30047376 DOI: 10.1016/S0140-6736(18)31364-3  0.371
2018 Bhattacharyya M, Whitney JB, Seaman M, Barouch DH, Penaloza-MacMaster P. T cell subset differentiation and antibody responses following antiretroviral therapy during SIV infection. Immunology. PMID 30014618 DOI: 10.1111/Imm.12985  0.41
2018 Alter G, Barouch D. Immune Correlate-Guided HIV Vaccine Design. Cell Host & Microbe. 24: 25-33. PMID 30001521 DOI: 10.1016/J.Chom.2018.06.012  0.503
2018 López-Camacho C, Abbink P, Larocca RA, Dejnirattisai W, Boyd M, Badamchi-Zadeh A, Wallace ZR, Doig J, Velazquez RS, Neto RDL, Coelho DF, Kim YC, Donald CL, Owsianka A, De Lorenzo G, ... ... Barouch DH, et al. Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors. Nature Communications. 9: 2441. PMID 29934593 DOI: 10.1038/s41467-018-04859-5  0.546
2018 Abbink P, Stephenson KE, Barouch DH. Zika virus vaccines. Nature Reviews. Microbiology. PMID 29921914 DOI: 10.1038/s41579-018-0039-7  0.469
2018 Barouch DH. A step forward for HIV vaccines. The Lancet. Hiv. 5: e338-e339. PMID 29898871 DOI: 10.1016/S2352-3018(18)30095-X  0.364
2018 Abbink P, Larocca RA, Dejnirattisai W, Peterson R, Nkolola JP, Borducchi EN, Supasa P, Mongkolsapaya J, Screaton GR, Barouch DH. Therapeutic and protective efficacy of a dengue antibody against Zika infection in rhesus monkeys. Nature Medicine. 24: 721-723. PMID 29867228 DOI: 10.1038/s41591-018-0056-0  0.331
2018 Kang ZH, Bricault CA, Borducchi EN, Stephenson KE, Seaman MS, Pau M, Schuitemaker H, van Manen D, Wegmann F, Barouch DH. Similar epitope specificities of IgG and IgA antibodies elicited by Ad26 vector prime, Env protein boost immunizations in rhesus monkeys. Journal of Virology. PMID 29793950 DOI: 10.1128/JVI.00537-18  0.552
2018 Bricault CA, Kovacs JM, Badamchi-Zadeh A, McKee K, Shields JL, Gunn BM, Neubauer GH, Ghantous F, Jennings J, Gillis L, Perry J, Nkolola JP, Alter G, Chen B, Stephenson KE, ... ... Barouch DH, et al. Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs. Journal of Virology. PMID 29643249 DOI: 10.1128/Jvi.00369-18  0.468
2018 Iampietro MJ, Larocca RA, Provine NM, Abbink P, Kang ZH, Bricault CA, Barouch DH. Immunogenicity and Cross-reactivity of Rhesus Adenoviral Vectors. Journal of Virology. PMID 29563285 DOI: 10.1128/JVI.00159-18  0.491
2018 Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, ... ... Barouch DH, et al. Corrigendum: An immunogenic personal neoantigen vaccine for patients with melanoma. Nature. 555: 402. PMID 29542692 DOI: 10.1038/Nature25145  0.373
2018 Blass E, Aid M, Martinot AJ, Larocca RA, Kang ZH, Badamchi-Zadeh A, Penaloza-MacMaster P, Reeves RK, Barouch DH. Adenovirus vector vaccination impacts NK cell rheostat function following LCMV infection. Journal of Virology. PMID 29514912 DOI: 10.1128/JVI.02103-17  0.424
2018 Klasse PJ, Ketas TJ, Cottrell CA, Ozorowski G, Debnath G, Camara D, Francomano E, Pugach P, Ringe RP, LaBranche CC, van Gils MJ, Bricault CA, Barouch DH, Crotty S, Silvestri G, et al. Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques. Plos Pathogens. 14: e1006913. PMID 29474444 DOI: 10.1371/Journal.Ppat.1006913  0.307
2018 Abbink P, Kirilova M, Boyd M, Mercado N, Li Z, Nityanandam R, Nanayakkara O, Peterson R, Larocca RA, Aid M, Tartaglia L, Mutetwa T, Blass E, Jetton D, Maxfield LF, ... ... Barouch DH, et al. Rapid Cloning of Novel Rhesus Adenoviral Vaccine Vectors. Journal of Virology. PMID 29298888 DOI: 10.1128/Jvi.01924-17  0.368
2017 Abbink P, Larocca RA, Visitsunthorn K, Boyd M, De La Barrera RA, Gromowski GD, Kirilova M, Peterson R, Li Z, Nanayakkara O, Nityanandam R, Mercado NB, Borducchi EN, Chandrashekar A, Jetton D, ... ... Barouch DH, et al. Durability and correlates of vaccine protection against Zika virus in rhesus monkeys. Science Translational Medicine. 9. PMID 29237759 DOI: 10.1126/scitranslmed.aao4163  0.556
2017 Modjarrad K, Lin L, George SL, Stephenson KE, Eckels KH, De La Barrera RA, Jarman RG, Sondergaard E, Tennant J, Ansel JL, Mills K, Koren M, Robb ML, Barrett J, Thompson J, ... ... Barouch DH, et al. Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials. Lancet (London, England). PMID 29217375 DOI: 10.1016/S0140-6736(17)33106-9  0.477
2017 Julg B, Liu PT, Wagh K, Fischer WM, Abbink P, Mercado NB, Whitney JB, Nkolola JP, McMahan K, Tartaglia LJ, Borducchi EN, Khatiwada S, Kamath M, LeSuer JA, Seaman MS, ... ... Barouch DH, et al. Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail. Science Translational Medicine. 9. PMID 28931655 DOI: 10.1126/Scitranslmed.Aao4235  0.303
2017 Xu L, Pegu A, Rao E, Doria-Rose N, Beninga J, McKee K, Lord DM, Wei RR, Deng G, Louder M, Schmidt SD, Mankoff Z, Wu L, Asokan M, Beil C, ... ... Barouch DH, et al. Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques. Science (New York, N.Y.). PMID 28931639 DOI: 10.1126/Science.Aan8630  0.375
2017 McCracken MK, Gromowski GD, Friberg HL, Lin X, Abbink P, De La Barrera R, Eckles KH, Garver LS, Boyd M, Jetton D, Barouch DH, Wise MC, Lewis BS, Currier JR, Modjarrad K, et al. Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques. Plos Pathogens. 13: e1006487. PMID 28771605 DOI: 10.1371/Journal.Ppat.1006487  0.356
2017 Julg B, Sok D, Schmidt SD, Abbink P, Newman RM, Broge T, Linde C, Nkolola J, Le K, Su D, Torabi J, Pack M, Pegu A, Allen TM, Mascola JR, ... ... Barouch DH, et al. Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity Against SHIV in Rhesus Monkeys. Journal of Virology. PMID 28768869 DOI: 10.1128/Jvi.01187-17  0.335
2017 Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, ... ... Barouch DH, et al. An immunogenic personal neoantigen vaccine for patients with melanoma. Nature. PMID 28678778 DOI: 10.1038/Nature22991  0.434
2017 Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, ... ... Barouch DH, et al. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 46: 1073-1088.e6. PMID 28636956 DOI: 10.1016/J.Immuni.2017.05.007  0.432
2017 Keele BF, Li W, Borducchi EN, Nkolola JP, Abbink P, Chen B, Seaman MS, Barouch DH. Adenovirus prime, Env protein boost vaccine protects against neutralization-resistant SIVsmE660 variants in rhesus monkeys. Nature Communications. 8: 15740. PMID 28580942 DOI: 10.1038/ncomms15740  0.465
2017 Julg B, Pegu A, Abbink P, Liu J, Brinkman A, Molloy K, Mojta S, Chandrashekar A, Callow K, Wang K, Chen X, Schmidt SD, Huang J, Koup RA, Seaman MS, ... ... Barouch DH, et al. Virological control by the CD4-binding site antibody N6 in SHIV-infected rhesus monkeys. Journal of Virology. PMID 28539448 DOI: 10.1128/JVI.00498-17  0.303
2017 Saunders KO, Nicely NI, Wiehe K, Bonsignori M, Meyerhoff RR, Parks R, Walkowicz WE, Aussedat B, Wu NR, Cai F, Vohra Y, Park PK, Eaton A, Go EP, Sutherland LL, ... ... Barouch DH, et al. Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. Cell Reports. 18: 2175-2188. PMID 28249163 DOI: 10.1016/J.Celrep.2017.02.003  0.578
2017 Barouch DH, Thomas SJ, Michael NL. Prospects for a Zika Virus Vaccine. Immunity. 46: 176-182. PMID 28228277 DOI: 10.1016/j.immuni.2017.02.005  0.492
2017 Brown EP, Dowell KG, Boesch AW, Normandin E, Mahan AE, Chu T, Barouch DH, Bailey-Kellogg C, Alter G, Ackerman ME. Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles. Journal of Immunological Methods. PMID 28163018 DOI: 10.1016/J.Jim.2017.01.010  0.45
2017 Ackerman ME, Barouch DH, Alter G. Systems serology for evaluation of HIV vaccine trials. Immunological Reviews. 275: 262-270. PMID 28133810 DOI: 10.1111/Imr.12503  0.552
2016 Larocca RA, Provine NM, Aid M, Iampietro MJ, Borducchi EN, Badamchi-Zadeh A, Abbink P, Ng'ang'a D, Bricault CA, Blass E, Penaloza-MacMaster P, Stephenson KE, Barouch DH. Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4(+) T cell responses that impair CD8(+) T cell function. Science Immunology. 1. PMID 28239679 DOI: 10.1126/sciimmunol.aaf7643  0.329
2016 Penaloza MacMaster P, Shields JL, Alayo QA, Cabral C, Jimenez J, Mondesir J, Chandrashekar A, Cabral JM, Lim M, Iampietro MJ, Provine NM, Bricault CA, Seaman M, Orlinger K, Aspoeck A, ... ... Barouch DH, et al. Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens. Vaccine. PMID 27899229 DOI: 10.1016/J.Vaccine.2016.11.063  0.551
2016 Borducchi EN, Cabral C, Stephenson KE, Liu J, Abbink P, Ng'ang'a D, Nkolola JP, Brinkman AL, Peter L, Lee BC, Jimenez J, Jetton D, Mondesir J, Mojta S, Chandrashekar A, ... ... Barouch DH, et al. Ad26/MVA Therapeutic Vaccination with TLR7 Stimulation in SIV-Infected Rhesus Monkeys. Nature. PMID 27841870 DOI: 10.1038/Nature20583  0.473
2016 Dowd KA, Ko SY, Morabito KM, Yang ES, Pelc RS, DeMaso CR, Castilho LR, Abbink P, Boyd M, Nityanandam R, Gordon DN, Gallagher JR, Chen X, Todd JP, Tsybovsky Y, ... ... Barouch DH, et al. Rapid development of a DNA vaccine for Zika virus. Science (New York, N.Y.). PMID 27708058 DOI: 10.1126/Science.Aai9137  0.502
2016 Penaloza-MacMaster P, Alayo QA, Ra J, Provine NM, Larocca R, Lee B, Barouch DH. Inhibitory receptor expression on memory CD8 T cells following Ad vector immunization. Vaccine. PMID 27566899 DOI: 10.1016/j.vaccine.2016.08.048  0.308
2016 Liu J, Ghneim K, Sok D, Bosche WJ, Li Y, Chipriano E, Berkemeier B, Oswald K, Borducchi E, Cabral C, Peter L, Brinkman A, Shetty M, Jimenez J, Mondesir J, ... ... Barouch DH, et al. Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus. Science (New York, N.Y.). PMID 27540005 DOI: 10.1126/Science.Aag0491  0.337
2016 Abbink P, Larocca RA, De La Barrera RA, Bricault CA, Moseley ET, Boyd M, Kirilova M, Li Z, Ng'ang'a D, Nanayakkara O, Nityanandam R, Mercado NB, Borducchi EN, Agarwal A, Brinkman AL, ... ... Barouch DH, et al. Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys. Science (New York, N.Y.). PMID 27492477 DOI: 10.1126/Science.Aah6157  0.544
2016 Stephenson KE, Neubauer GH, Bricault CA, Shields J, Bayne M, Reimer U, Pawlowski N, Knaute T, Zerweck J, Seaman MS, Rosenberg ES, Barouch DH. Antibody Responses After Analytic Treatment Interruption in Human Immunodeficiency Virus-1-Infected Individuals on Early Initiated Antiretroviral Therapy. Open Forum Infectious Diseases. 3: ofw100. PMID 27419172 DOI: 10.1093/ofid/ofw100  0.328
2016 Larocca RA, Abbink P, Peron JP, Zanotto PM, Iampietro MJ, Badamchi-Zadeh A, Boyd M, Ng'ang'a D, Kirilova M, Nityanandam R, Mercado NB, Li Z, Moseley ET, Bricault CA, Borducchi EN, ... ... Barouch DH, et al. Vaccine protection against Zika virus from Brazil. Nature. PMID 27355570 DOI: 10.1038/nature18952  0.544
2016 Stephenson KE, D'Couto HT, Barouch DH. New concepts in HIV-1 vaccine development. Current Opinion in Immunology. 41: 39-46. PMID 27268856 DOI: 10.1016/j.coi.2016.05.011  0.438
2016 Mahan AE, Jennewein MF, Suscovich T, Dionne K, Tedesco J, Chung AW, Streeck H, Pau M, Schuitemaker H, Francis D, Fast P, Laufer D, Walker BD, Baden L, Barouch DH, et al. Correction: Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination. Plos Pathogens. 12: e1005694. PMID 27253391 DOI: 10.1371/Journal.Ppat.1005694  0.411
2016 Moldt B, Le KM, Carnathan DG, Whitney JB, Schultz N, Lewis MG, Borducchi EN, Smith KM, Mackel JJ, Sweat SL, Hodges AP, Godzik A, Parren PW, Silvestri G, Barouch DH, et al. Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques. Aids (London, England). 30: 1543-1551. PMID 27243773 DOI: 10.1097/Qad.0000000000001102  0.306
2016 Barouch DH, Ghneim K, Bosche WJ, Li Y, Berkemeier B, Hull M, Bhattacharyya S, Cameron M, Liu J, Smith K, Borducchi E, Cabral C, Peter L, Brinkman A, Shetty M, et al. Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys. Cell. PMID 27085913 DOI: 10.1016/J.Cell.2016.03.021  0.37
2016 Mahan AE, Jennewein MF, Suscovich T, Dionne K, Tedesco J, Chung AW, Streeck H, Pau M, Schuitemaker H, Francis D, Fast P, Laufer D, Walker BD, Baden L, Barouch DH, et al. Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination. Plos Pathogens. 12: e1005456. PMID 26982805 DOI: 10.1371/Journal.Ppat.1005456  0.375
2016 Handley SA, Desai C, Zhao G, Droit L, Monaco CL, Schroeder AC, Nkolola JP, Norman ME, Miller AD, Wang D, Barouch DH, Virgin HW. SIV Infection-Mediated Changes in Gastrointestinal Bacterial Microbiome and Virome Are Associated with Immunodeficiency and Prevented by Vaccination. Cell Host & Microbe. 19: 323-335. PMID 26962943 DOI: 10.1016/J.Chom.2016.02.010  0.489
2016 Provine NM, Badamchi-Zadeh A, Bricault CA, Penaloza-MacMaster P, Larocca RA, Borducchi EN, Seaman MS, Barouch DH. Transient CD4+ T cell depletion results in the delayed development of functional vaccine-elicited antibody responses. Journal of Virology. PMID 26865713 DOI: 10.1128/JVI.00039-16  0.365
2016 Tartaglia LJ, Chang HW, Lee BC, Abbink P, Ng'ang'a D, Boyd M, Lavine CL, Lim SY, Sanisetty S, Whitney JB, Seaman MS, Rolland M, Tovanabutra S, Ananworanich J, Robb ML, ... ... Barouch DH, et al. Production of Mucosally Transmissible SHIV Challenge Stocks from HIV-1 Circulating Recombinant Form 01_AE env Sequences. Plos Pathogens. 12: e1005431. PMID 26849216 DOI: 10.1371/Journal.Ppat.1005431  0.322
2016 Baden LR, Karita E, Mutua G, Bekker LG, Gray G, Page-Shipp L, Walsh SR, Nyombayire J, Anzala O, Roux S, Laher F, Innes C, Seaman MS, Cohen YZ, Peter L, ... ... Barouch DH, et al. Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention: A Randomized Trial. Annals of Internal Medicine. PMID 26833336 DOI: 10.7326/M15-0880  0.366
2015 Chung AW, Kumar MP, Arnold KB, Yu WH, Schoen MK, Dunphy LJ, Suscovich TJ, Frahm N, Linde C, Mahan AE, Hoffner M, Streeck H, Ackerman ME, McElrath MJ, Schuitemaker H, ... ... Barouch DH, et al. Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology. Cell. 163: 988-98. PMID 26544943 DOI: 10.1016/J.Cell.2015.10.027  0.515
2015 Maxfield LF, Abbink P, Stephenson KE, Borducchi EN, Ng'ang'a D, Kirilova MM, Paulino N, Boyd M, Shabram P, Ruan Q, Patel M, Barouch DH. Attenuation of Replication-Competent Adenovirus Serotype 26 Vaccines by Vectorization. Clinical and Vaccine Immunology : Cvi. 22: 1166-75. PMID 26376928 DOI: 10.1128/CVI.00510-15  0.337
2015 Reeves RK, Li H, Jost S, Blass E, Li H, Schafer JL, Varner V, Manickam C, Eslamizar L, Altfeld M, von Andrian UH, Barouch DH. Antigen-specific NK cell memory in rhesus macaques. Nature Immunology. PMID 26193080 DOI: 10.1038/Ni.3227  0.427
2015 Barouch DH, Alter G, Broge T, Linde C, Ackerman ME, Brown EP, Borducchi EN, Smith KM, Nkolola JP, Liu J, Shields J, Parenteau L, Whitney JB, Abbink P, Ng'ang'a DM, et al. Protective efficacy of adenovirus-protein vaccines against SIV challenges in rhesus monkeys. Science (New York, N.Y.). PMID 26138104 DOI: 10.1126/Science.Aab3886  0.535
2015 Alter G, Barouch DH. Natural evolution of broadly neutralizing antibodies. Cell. 161: 427-8. PMID 25910199 DOI: 10.1016/J.Cell.2015.04.007  0.31
2015 Penaloza-MacMaster P, Barber DL, Wherry EJ, Provine NM, Teigler JE, Parenteau L, Blackmore S, Borducchi EN, Larocca RA, Yates KB, Shen H, Haining WN, Sommerstein R, Pinschewer DD, Ahmed R, ... Barouch DH, et al. Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection. Science (New York, N.Y.). 347: 278-82. PMID 25593185 DOI: 10.1126/Science.Aaa2148  0.433
2015 Bricault CA, Kovacs JM, Nkolola JP, Yusim K, Giorgi EE, Shields JL, Perry J, Lavine CL, Cheung A, Ellingson-Strouss K, Rademeyer C, Gray GE, Williamson C, Stamatatos L, Seaman MS, ... ... Barouch DH, et al. A multivalent clade C HIV-1 Env trimer cocktail elicits a higher magnitude of neutralizing antibodies than any individual component. Journal of Virology. 89: 2507-19. PMID 25540368 DOI: 10.1128/Jvi.03331-14  0.362
2015 Chang HW, Tartaglia LJ, Whitney JB, Lim SY, Sanisetty S, Lavine CL, Seaman MS, Rademeyer C, Williamson C, Ellingson-Strouss K, Stamatatos L, Kublin J, Barouch DH. Generation and evaluation of clade C simian-human immunodeficiency virus challenge stocks. Journal of Virology. 89: 1965-74. PMID 25473043 DOI: 10.1128/Jvi.03279-14  0.307
2015 Abbink P, Maxfield LF, Ng'ang'a D, Borducchi EN, Iampietro MJ, Bricault CA, Teigler JE, Blackmore S, Parenteau L, Wagh K, Handley SA, Zhao G, Virgin HW, Korber B, Barouch DH. Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors. Journal of Virology. 89: 1512-22. PMID 25410856 DOI: 10.1128/Jvi.02950-14  0.478
2015 Baden LR, Liu J, Li H, Johnson JA, Walsh SR, Kleinjan JA, Engelson BA, Peter L, Abbink P, Milner DA, Golden KL, Viani KL, Stachler MD, Chen BJ, Pau MG, ... ... Barouch DH, et al. Induction of HIV-1-specific mucosal immune responses following intramuscular recombinant adenovirus serotype 26 HIV-1 vaccination of humans. The Journal of Infectious Diseases. 211: 518-28. PMID 25165165 DOI: 10.1093/infdis/jiu485  0.425
2014 Hokey DA, Wachholder R, Darrah PA, Bolton DL, Barouch DH, Hill K, Dheenadhayalan V, Schwander S, Godin CS, Douoguih M, Pau MG, Seder RA, Roederer M, Sadoff JC, Sizemore D. A nonhuman primate toxicology and immunogenicity study evaluating aerosol delivery of AERAS-402/Ad35 vaccine: Evidence for transient t cell responses in peripheral blood and robust sustained responses in the lungs. Human Vaccines & Immunotherapeutics. 10: 2199-210. PMID 25424923 DOI: 10.4161/hv.29108  0.472
2014 Barouch DH, Michael NL. Accelerating HIV-1 Vaccine Efficacy Trials. Cell. 159: 969-72. PMID 25416935 DOI: 10.1016/j.cell.2014.10.046  0.33
2014 Barouch DH, Picker LJ. Novel vaccine vectors for HIV-1. Nature Reviews. Microbiology. 12: 765-71. PMID 25296195 DOI: 10.1038/nrmicro3360  0.453
2014 Li H, Stephenson KE, Kang ZH, Lavine CL, Seaman MS, Barouch DH. Common features of mucosal and peripheral antibody responses elicited by candidate HIV-1 vaccines in rhesus monkeys. Journal of Virology. 88: 13510-5. PMID 25210178 DOI: 10.1128/JVI.02095-14  0.506
2014 Pejawar-Gaddy S, Kovacs JM, Barouch DH, Chen B, Irvine DJ. Design of lipid nanocapsule delivery vehicles for multivalent display of recombinant Env trimers in HIV vaccination. Bioconjugate Chemistry. 25: 1470-8. PMID 25020048 DOI: 10.1021/Bc5002246  0.354
2014 Teigler JE, Kagan JC, Barouch DH. Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. Journal of Virology. 88: 10354-63. PMID 24991003 DOI: 10.1128/Jvi.00936-14  0.411
2014 Nkolola JP, Bricault CA, Cheung A, Shields J, Perry J, Kovacs JM, Giorgi E, van Winsen M, Apetri A, Brinkman-van der Linden EC, Chen B, Korber B, Seaman MS, Barouch DH. Characterization and immunogenicity of a novel mosaic M HIV-1 gp140 trimer. Journal of Virology. 88: 9538-52. PMID 24965452 DOI: 10.1128/Jvi.01739-14  0.352
2014 Manrique A, Adams E, Barouch DH, Fast P, Graham BS, Kim JH, Kublin JG, McCluskey M, Pantaleo G, Robinson HL, Russell N, Snow W, Johnston MI. The immune space: a concept and template for rationalizing vaccine development. Aids Research and Human Retroviruses. 30: 1017-22. PMID 24857015 DOI: 10.1089/Aid.2014.0040  0.512
2014 Dugast AS, Chan Y, Hoffner M, Licht A, Nkolola J, Li H, Streeck H, Suscovich TJ, Ghebremichael M, Ackerman ME, Barouch DH, Alter G. Lack of protection following passive transfer of polyclonal highly functional low-dose non-neutralizing antibodies. Plos One. 9: e97229. PMID 24820481 DOI: 10.1371/Journal.Pone.0097229  0.363
2014 Penaloza-MacMaster P, Teigler JE, Obeng RC, Kang ZH, Provine NM, Parenteau L, Blackmore S, Ra J, Borducchi EN, Barouch DH. Augmented replicative capacity of the boosting antigen improves the protective efficacy of heterologous prime-boost vaccine regimens. Journal of Virology. 88: 6243-54. PMID 24648461 DOI: 10.1128/JVI.00406-14  0.549
2014 Balandya E, Miller AD, Beck M, Liu J, Li H, Borducchi E, Smith K, Cabral C, Stanley K, Maxfield LF, Barouch DH. Adenovirus serotype 26 and 35 vectors induce simian immunodeficiency virus-specific T lymphocyte responses in foreskin in rhesus monkeys. Journal of Virology. 88: 3756-65. PMID 24429370 DOI: 10.1128/JVI.03771-13  0.459
2014 Teigler JE, Phogat S, Franchini G, Hirsch VM, Michael NL, Barouch DH. The canarypox virus vector ALVAC induces distinct cytokine responses compared to the vaccinia virus-based vectors MVA and NYVAC in rhesus monkeys. Journal of Virology. 88: 1809-14. PMID 24257612 DOI: 10.1128/JVI.02386-13  0.506
2014 Stephenson KE, Barouch DH. A global approach to HIV-1 vaccine development. Immunological Reviews. 254: 295-304. PMID 23772627 DOI: 10.1111/imr.12073  0.411
2013 Barouch DH. The quest for an HIV-1 vaccine--moving forward. The New England Journal of Medicine. 369: 2073-6. PMID 24283223 DOI: 10.1056/NEJMp1312711  0.363
2013 Barouch DH, Stephenson KE, Borducchi EN, Smith K, Stanley K, McNally AG, Liu J, Abbink P, Maxfield LF, Seaman MS, Dugast AS, Alter G, Ferguson M, Li W, Earl PL, et al. Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys. Cell. 155: 531-9. PMID 24243013 DOI: 10.1016/J.Cell.2013.09.061  0.403
2013 Nabi G, Genannt Bonsmann MS, Tenbusch M, Gardt O, Barouch DH, Temchura V, Uberla K. GagPol-specific CD4⁺ T-cells increase the antibody response to Env by intrastructural help. Retrovirology. 10: 117. PMID 24156704 DOI: 10.1186/1742-4690-10-117  0.441
2013 Li AV, Moon JJ, Abraham W, Suh H, Elkhader J, Seidman MA, Yen M, Im EJ, Foley MH, Barouch DH, Irvine DJ. Generation of effector memory T cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination. Science Translational Medicine. 5: 204ra130. PMID 24068737 DOI: 10.1126/Scitranslmed.3006516  0.482
2013 Johnson JA, Barouch DH, Baden LR. Nonreplicating vectors in HIV vaccines. Current Opinion in Hiv and Aids. 8: 412-20. PMID 23925001 DOI: 10.1097/COH.0b013e328363d3b7  0.372
2013 Im EJ, Borducchi EN, Provine NM, McNally AG, Li S, Frankel FR, Barouch DH. An attenuated Listeria monocytogenes vector primes more potent simian immunodeficiency virus-specific mucosal immunity than DNA vaccines in mice. Journal of Virology. 87: 4751-5. PMID 23388715 DOI: 10.1128/JVI.03085-12  0.52
2013 DeMuth PC, Min Y, Huang B, Kramer JA, Miller AD, Barouch DH, Hammond PT, Irvine DJ. Polymer multilayer tattooing for enhanced DNA vaccination. Nature Materials. 12: 367-76. PMID 23353628 DOI: 10.1038/Nmat3550  0.415
2013 Yusim K, Dilan R, Borducchi E, Stanley K, Giorgi E, Fischer W, Theiler J, Marcotrigiano J, Korber B, Barouch DH. Hepatitis C genotype 1 mosaic vaccines are immunogenic in mice and induce stronger T-cell responses than natural strains. Clinical and Vaccine Immunology : Cvi. 20: 302-5. PMID 23221002 DOI: 10.1128/Cvi.00605-12  0.356
2013 Tan WG, Jin HT, West EE, Penaloza-MacMaster P, Wieland A, Zilliox MJ, McElrath MJ, Barouch DH, Ahmed R. Comparative analysis of simian immunodeficiency virus gag-specific effector and memory CD8+ T cells induced by different adenovirus vectors. Journal of Virology. 87: 1359-72. PMID 23175355 DOI: 10.1128/Jvi.02055-12  0.31
2013 Penaloza-MacMaster P, Provine NM, Ra J, Borducchi EN, McNally A, Simmons NL, Iampietro MJ, Barouch DH. Alternative serotype adenovirus vaccine vectors elicit memory T cells with enhanced anamnestic capacity compared to Ad5 vectors. Journal of Virology. 87: 1373-84. PMID 23152535 DOI: 10.1128/JVI.02058-12  0.32
2013 Baden LR, Walsh SR, Seaman MS, Tucker RP, Krause KH, Patel A, Johnson JA, Kleinjan J, Yanosick KE, Perry J, Zablowsky E, Abbink P, Peter L, Iampietro MJ, Cheung A, ... ... Barouch DH, et al. First-in-human evaluation of the safety and immunogenicity of a recombinant adenovirus serotype 26 HIV-1 Env vaccine (IPCAVD 001). The Journal of Infectious Diseases. 207: 240-7. PMID 23125444 DOI: 10.1093/Infdis/Jis670  0.382
2013 Barouch DH, Liu J, Peter L, Abbink P, Iampietro MJ, Cheung A, Alter G, Chung A, Dugast AS, Frahm N, McElrath MJ, Wenschuh H, Reimer U, Seaman MS, Pau MG, et al. Characterization of humoral and cellular immune responses elicited by a recombinant adenovirus serotype 26 HIV-1 Env vaccine in healthy adults (IPCAVD 001). The Journal of Infectious Diseases. 207: 248-56. PMID 23125443 DOI: 10.1093/Infdis/Jis671  0.473
2012 Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/J.Chom.2012.09.008  0.45
2012 Li H, Rhee EG, Masek-Hammerman K, Teigler JE, Abbink P, Barouch DH. Adenovirus serotype 26 utilizes CD46 as a primary cellular receptor and only transiently activates T lymphocytes following vaccination of rhesus monkeys. Journal of Virology. 86: 10862-5. PMID 22811531 DOI: 10.1128/JVI.00928-12  0.374
2012 Teigler JE, Iampietro MJ, Barouch DH. Vaccination with adenovirus serotypes 35, 26, and 48 elicits higher levels of innate cytokine responses than adenovirus serotype 5 in rhesus monkeys. Journal of Virology. 86: 9590-8. PMID 22787208 DOI: 10.1128/JVI.00740-12  0.419
2012 Stephenson KE, Li H, Walker BD, Michael NL, Barouch DH. Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following simian immunodeficiency virus challenges of vaccinated rhesus monkeys. Journal of Virology. 86: 9583-9. PMID 22761379 DOI: 10.1128/JVI.00996-12  0.532
2012 Liu J, Li H, Iampietro MJ, Barouch DH. Accelerated heterologous adenovirus prime-boost SIV vaccine in neonatal rhesus monkeys. Journal of Virology. 86: 7829-35. PMID 22593160 DOI: 10.1128/JVI.00512-12  0.459
2012 Barouch DH, Klasse PJ, Dufour J, Veazey RS, Moore JP. Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission. Proceedings of the National Academy of Sciences of the United States of America. 109: 8694-8. PMID 22586094 DOI: 10.1073/pnas.1203183109  0.511
2012 Stephenson KE, Hural J, Buchbinder SP, Sinangil F, Barouch DH. Preexisting adenovirus seropositivity is not associated with increased HIV-1 acquisition in three HIV-1 vaccine efficacy trials. The Journal of Infectious Diseases. 205: 1806-10. PMID 22492863 DOI: 10.1093/infdis/jis285  0.307
2012 Barouch DH, Liu J, Li H, Maxfield LF, Abbink P, Lynch DM, Iampietro MJ, SanMiguel A, Seaman MS, Ferrari G, Forthal DN, Ourmanov I, Hirsch VM, Carville A, Mansfield KG, et al. Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys. Nature. 482: 89-93. PMID 22217938 DOI: 10.1038/Nature10766  0.518
2012 Kaufman DR, Li F, Cruz AN, Self SG, Barouch DH. Focus and breadth of cellular immune responses elicited by a heterologous insert prime-boost vaccine regimen in rhesus monkeys. Vaccine. 30: 506-9. PMID 22133509 DOI: 10.1016/J.Vaccine.2011.11.079  0.48
2012 Bradley RR, Lynch DM, Iampietro MJ, Borducchi EN, Barouch DH. Adenovirus serotype 5 neutralizing antibodies target both hexon and fiber following vaccination and natural infection. Journal of Virology. 86: 625-9. PMID 22072776 DOI: 10.1128/JVI.06254-11  0.422
2012 Bradley RR, Maxfield LF, Lynch DM, Iampietro MJ, Borducchi EN, Barouch DH. Adenovirus serotype 5-specific neutralizing antibodies target multiple hexon hypervariable regions. Journal of Virology. 86: 1267-72. PMID 22072746 DOI: 10.1128/JVI.06165-11  0.336
2011 Kaufman DR, De Calisto J, Simmons NL, Cruz AN, Villablanca EJ, Mora JR, Barouch DH. Vitamin A deficiency impairs vaccine-elicited gastrointestinal immunity. Journal of Immunology (Baltimore, Md. : 1950). 187: 1877-83. PMID 21765014 DOI: 10.4049/jimmunol.1101248  0.465
2011 Barouch DH, Kik SV, Weverling GJ, Dilan R, King SL, Maxfield LF, Clark S, Ng'ang'a D, Brandariz KL, Abbink P, Sinangil F, de Bruyn G, Gray GE, Roux S, Bekker LG, et al. International seroepidemiology of adenovirus serotypes 5, 26, 35, and 48 in pediatric and adult populations. Vaccine. 29: 5203-9. PMID 21619905 DOI: 10.1016/J.Vaccine.2011.05.025  0.311
2011 Barouch DH. Novel adenovirus vector-based vaccines for HIV-1. Current Opinion in Hiv and Aids. 5: 386-90. PMID 20978378 DOI: 10.1097/COH.0b013e32833cfe4c  0.493
2011 Rhee EG, Blattman JN, Kasturi SP, Kelley RP, Kaufman DR, Lynch DM, La Porte A, Simmons NL, Clark SL, Pulendran B, Greenberg PD, Barouch DH. Multiple innate immune pathways contribute to the immunogenicity of recombinant adenovirus vaccine vectors. Journal of Virology. 85: 315-23. PMID 20962088 DOI: 10.1128/Jvi.01597-10  0.476
2010 Wilks AB, Christian EC, Seaman MS, Sircar P, Carville A, Gomez CE, Esteban M, Pantaleo G, Barouch DH, Letvin NL, Permar SR. Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 185: 7097-106. PMID 21041730 DOI: 10.4049/Jimmunol.1002751  0.648
2010 Masek-Hammerman K, Li H, Liu J, Abbink P, La Porte A, O'Brien KL, Whitney JB, Carville A, Mansfield KG, Barouch DH. Mucosal trafficking of vector-specific CD4+ T lymphocytes following vaccination of rhesus monkeys with adenovirus serotype 5. Journal of Virology. 84: 9810-6. PMID 20686023 DOI: 10.1128/Jvi.01157-10  0.425
2010 Liu J, Keele BF, Li H, Keating S, Norris PJ, Carville A, Mansfield KG, Tomaras GD, Haynes BF, Kolodkin-Gal D, Letvin NL, Hahn BH, Shaw GM, Barouch DH. Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. Journal of Virology. 84: 10406-12. PMID 20686016 DOI: 10.1128/Jvi.01155-10  0.583
2010 Rhee EG, Kelley RP, Agarwal I, Lynch DM, La Porte A, Simmons NL, Clark SL, Barouch DH. TLR4 ligands augment antigen-specific CD8+ T lymphocyte responses elicited by a viral vaccine vector. Journal of Virology. 84: 10413-9. PMID 20631129 DOI: 10.1128/JVI.00928-10  0.451
2010 Lim SY, Chan T, Gelman RS, Whitney JB, O'Brien KL, Barouch DH, Goldstein DB, Haynes BF, Letvin NL. Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys. Plos Genetics. 6: e1000997. PMID 20585621 DOI: 10.1371/Journal.Pgen.1000997  0.435
2010 Rosenberg ES, Graham BS, Chan ES, Bosch RJ, Stocker V, Maenza J, Markowitz M, Little S, Sax PE, Collier AC, Nabel G, Saindon S, Flynn T, Kuritzkes D, Barouch DH, et al. Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection. Plos One. 5: e10555. PMID 20479938 DOI: 10.1371/Journal.Pone.0010555  0.338
2010 Kaufman DR, Bivas-Benita M, Simmons NL, Miller D, Barouch DH. Route of adenovirus-based HIV-1 vaccine delivery impacts the phenotype and trafficking of vaccine-elicited CD8+ T lymphocytes. Journal of Virology. 84: 5986-96. PMID 20357087 DOI: 10.1128/JVI.02563-09  0.436
2010 Barouch DH, O'Brien KL, Simmons NL, King SL, Abbink P, Maxfield LF, Sun YH, La Porte A, Riggs AM, Lynch DM, Clark SL, Backus K, Perry JR, Seaman MS, Carville A, et al. Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys. Nature Medicine. 16: 319-23. PMID 20173752 DOI: 10.1038/Nm.2089  0.372
2010 Barouch DH, Korber B. HIV-1 vaccine development after STEP. Annual Review of Medicine. 61: 153-67. PMID 20059334 DOI: 10.1146/annurev.med.042508.093728  0.439
2010 Nkolola JP, Peng H, Settembre EC, Freeman M, Grandpre LE, Devoy C, Lynch DM, La Porte A, Simmons NL, Bradley R, Montefiori DC, Seaman MS, Chen B, Barouch DH. Breadth of neutralizing antibodies elicited by stable, homogeneous clade A and clade C HIV-1 gp140 envelope trimers in guinea pigs. Journal of Virology. 84: 3270-9. PMID 20053749 DOI: 10.1128/JVI.02252-09  0.36
2010 Thorner AR, Barouch DH. HIV-1 vaccine development: progress and prospects. Current Infectious Disease Reports. 9: 71-5. PMID 17254507 DOI: 10.1007/s11908-007-0025-0  0.494
2009 O'Brien KL, Liu J, King SL, Sun YH, Schmitz JE, Lifton MA, Hutnick NA, Betts MR, Dubey SA, Goudsmit J, Shiver JW, Robertson MN, Casimiro DR, Barouch DH. Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans. Nature Medicine. 15: 873-5. PMID 19620961 DOI: 10.1038/Nm.1991  0.396
2009 Hudgens MG, Gilbert PB, Mascola JR, Wu CD, Barouch DH, Self SG. Power to detect the effects of HIV vaccination in repeated low-dose challenge experiments. The Journal of Infectious Diseases. 200: 609-13. PMID 19591571 DOI: 10.1086/600891  0.333
2009 Barouch DH, Liu J, Lynch DM, O'Brien KL, La Porte A, Simmons NL, Riggs AM, Clark S, Abbink P, Montefiori DC, Landucci G, Forthal DN, Self SG, Carville A, Mansfield K, et al. Protective efficacy of a single immunization of a chimeric adenovirus vector-based vaccine against simian immunodeficiency virus challenge in rhesus monkeys. Journal of Virology. 83: 9584-90. PMID 19553307 DOI: 10.1128/Jvi.00821-09  0.535
2009 Grandpre LE, Duke-Cohan JS, Ewald BA, Devoy C, Barouch DH, Letvin NL, Reinherz EL, Baden LR, Dolin R, Seaman MS. Immunogenicity of recombinant Modified Vaccinia Ankara following a single or multi-dose vaccine regimen in rhesus monkeys. Vaccine. 27: 1549-56. PMID 19168105 DOI: 10.1016/j.vaccine.2009.01.010  0.691
2009 Liu J, O'Brien KL, Lynch DM, Simmons NL, La Porte A, Riggs AM, Abbink P, Coffey RT, Grandpre LE, Seaman MS, Landucci G, Forthal DN, Montefiori DC, Carville A, Mansfield KG, ... ... Barouch DH, et al. Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature. 457: 87-91. PMID 18997770 DOI: 10.1038/Nature07469  0.543
2008 Barouch DH. HIV vaccine trial canceled. Aids Clinical Care. 20: 69. PMID 18841618  0.347
2008 Barouch DH. Challenges in the development of an HIV-1 vaccine. Nature. 455: 613-9. PMID 18833271 DOI: 10.1038/nature07352  0.383
2008 Kaufman DR, Liu J, Carville A, Mansfield KG, Havenga MJ, Goudsmit J, Barouch DH. Trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination. Journal of Immunology (Baltimore, Md. : 1950). 181: 4188-98. PMID 18768876 DOI: 10.4049/Jimmunol.181.6.4188  0.455
2008 Santra S, Korber BT, Muldoon M, Barouch DH, Nabel GJ, Gao F, Hahn BH, Haynes BF, Letvin NL. A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys. Proceedings of the National Academy of Sciences of the United States of America. 105: 10489-94. PMID 18650391 DOI: 10.1073/Pnas.0803352105  0.628
2008 Kaufman DR, Goudsmit J, Holterman L, Ewald BA, Denholtz M, Devoy C, Giri A, Grandpre LE, Heraud JM, Franchini G, Seaman MS, Havenga MJ, Barouch DH. Differential antigen requirements for protection against systemic and intranasal vaccinia virus challenges in mice. Journal of Virology. 82: 6829-37. PMID 18448519 DOI: 10.1128/Jvi.00353-08  0.493
2008 Barouch DH. Bovine adenovirus vectored vaccine for avian influenza. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 807-8. PMID 18432270 DOI: 10.1038/mt.2008.47  0.446
2008 Barouch DH. HIV-1 vaccine candidate ineffective. Aids Clinical Care. 19: 93. PMID 18399000  0.369
2008 Liu J, Kjeken R, Mathiesen I, Barouch DH. Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporation. Journal of Virology. 82: 5643-9. PMID 18353952 DOI: 10.1128/JVI.02564-07  0.493
2008 Liu J, Ewald BA, Lynch DM, Denholtz M, Abbink P, Lemckert AA, Carville A, Mansfield KG, Havenga MJ, Goudsmit J, Barouch DH. Magnitude and phenotype of cellular immune responses elicited by recombinant adenovirus vectors and heterologous prime-boost regimens in rhesus monkeys. Journal of Virology. 82: 4844-52. PMID 18337575 DOI: 10.1128/Jvi.02616-07  0.397
2007 Abbink P, Lemckert AA, Ewald BA, Lynch DM, Denholtz M, Smits S, Holterman L, Damen I, Vogels R, Thorner AR, O'Brien KL, Carville A, Mansfield KG, Goudsmit J, Havenga MJ, ... Barouch DH, et al. Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D. Journal of Virology. 81: 4654-63. PMID 17329340 DOI: 10.1128/Jvi.02696-06  0.359
2006 Thorner AR, Lemckert AA, Goudsmit J, Lynch DM, Ewald BA, Denholtz M, Havenga MJ, Barouch DH. Immunogenicity of heterologous recombinant adenovirus prime-boost vaccine regimens is enhanced by circumventing vector cross-reactivity. Journal of Virology. 80: 12009-16. PMID 17035318 DOI: 10.1128/Jvi.01749-06  0.492
2006 Thorner AR, Vogels R, Kaspers J, Weverling GJ, Holterman L, Lemckert AA, Dilraj A, McNally LM, Jeena PM, Jepsen S, Abbink P, Nanda A, Swanson PE, Bates AT, O'Brien KL, ... ... Barouch DH, et al. Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa. Journal of Clinical Microbiology. 44: 3781-3. PMID 17021110 DOI: 10.1128/Jcm.01249-06  0.365
2006 Liu J, Ewald BA, Lynch DM, Nanda A, Sumida SM, Barouch DH. Modulation of DNA vaccine-elicited CD8+ T-lymphocyte epitope immunodominance hierarchies Journal of Virology. 80: 11991-11997. PMID 17005652 DOI: 10.1128/JVI.01348-06  0.521
2006 Lemckert AA, Grimbergen J, Smits S, Hartkoorn E, Holterman L, Berkhout B, Barouch DH, Vogels R, Quax P, Goudsmit J, Havenga MJ. Generation of a novel replication-incompetent adenoviral vector derived from human adenovirus type 49: manufacture on PER.C6 cells, tropism and immunogenicity. The Journal of General Virology. 87: 2891-9. PMID 16963747 DOI: 10.1099/Vir.0.82079-0  0.501
2006 Roberts DM, Nanda A, Havenga MJ, Abbink P, Lynch DM, Ewald BA, Liu J, Thorner AR, Swanson PE, Gorgone DA, Lifton MA, Lemckert AA, Holterman L, Chen B, Dilraj A, ... ... Barouch DH, et al. Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity. Nature. 441: 239-43. PMID 16625206 DOI: 10.1038/Nature04721  0.412
2006 Barouch DH. Rational design of gene-based vaccines. The Journal of Pathology. 208: 283-9. PMID 16362986 DOI: 10.1002/path.1874  0.473
2005 Nanda A, Lynch DM, Goudsmit J, Lemckert AA, Ewald BA, Sumida SM, Truitt DM, Abbink P, Kishko MG, Gorgone DA, Lifton MA, Shen L, Carville A, Mansfield KG, Havenga MJ, ... Barouch DH, et al. Immunogenicity of recombinant fiber-chimeric adenovirus serotype 35 vector-based vaccines in mice and rhesus monkeys. Journal of Virology. 79: 14161-8. PMID 16254351 DOI: 10.1128/Jvi.79.22.14161-14168.2005  0.32
2005 Peyerl FW, Barouch DH, Bazick HS, Manuel E, Letvin NL. Use of molecular beacons for rapid, real-time, quantitative monitoring of cytotoxic T-lymphocyte epitope mutations in simian immunodeficiency virus. Journal of Clinical Microbiology. 43: 4773-9. PMID 16145140 DOI: 10.1128/Jcm.43.9.4773-4779.2005  0.792
2005 Lemckert AA, Sumida SM, Holterman L, Vogels R, Truitt DM, Lynch DM, Nanda A, Ewald BA, Gorgone DA, Lifton MA, Goudsmit J, Havenga MJ, Barouch DH. Immunogenicity of heterologous prime-boost regimens involving recombinant adenovirus serotype 11 (Ad11) and Ad35 vaccine vectors in the presence of anti-ad5 immunity. Journal of Virology. 79: 9694-701. PMID 16014931 DOI: 10.1128/Jvi.79.15.9694-9701.2005  0.43
2005 Barouch DH, Yang ZY, Kong WP, Korioth-Schmitz B, Sumida SM, Truitt DM, Kishko MG, Arthur JC, Miura A, Mascola JR, Letvin NL, Nabel GJ. A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates. Journal of Virology. 79: 8828-34. PMID 15994776 DOI: 10.1128/Jvi.79.14.8828-8834.2005  0.644
2005 Sumida SM, Truitt DM, Lemckert AA, Vogels R, Custers JH, Addo MM, Lockman S, Peter T, Peyerl FW, Kishko MG, Jackson SS, Gorgone DA, Lifton MA, Essex M, Walker BD, ... ... Barouch DH, et al. Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein. Journal of Immunology (Baltimore, Md. : 1950). 174: 7179-85. PMID 15905562 DOI: 10.4049/Jimmunol.174.11.7179  0.774
2005 Santra S, Seaman MS, Xu L, Barouch DH, Lord CI, Lifton MA, Gorgone DA, Beaudry KR, Svehla K, Welcher B, Chakrabarti BK, Huang Y, Yang ZY, Mascola JR, Nabel GJ, et al. Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. Journal of Virology. 79: 6516-22. PMID 15858035 DOI: 10.1128/Jvi.79.10.6516-6522.2005  0.651
2005 Sun Y, Schmitz JE, Acierno PM, Santra S, Subbramanian RA, Barouch DH, Gorgone DA, Lifton MA, Beaudry KR, Manson K, Philippon V, Xu L, Maecker HT, Mascola JR, Panicali D, et al. Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 174: 4753-60. PMID 15814700 DOI: 10.4049/Jimmunol.174.8.4753  0.54
2005 Barouch DH, Nabel GJ. Adenovirus vector-based vaccines for human immunodeficiency virus type 1. Human Gene Therapy. 16: 149-56. PMID 15761255 DOI: 10.1089/Hum.2005.16.149  0.47
2005 Barouch DH, Powers J, Truitt DM, Kishko MG, Arthur JC, Peyerl FW, Kuroda MJ, Gorgone DA, Lifton MA, Lord CI, Hirsch VM, Montefiori DC, Carville A, Mansfield KG, Kunstman KJ, et al. Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants. Nature Immunology. 6: 247-52. PMID 15685174 DOI: 10.1038/Ni1167  0.753
2004 Peyerl FW, Bazick HS, Newberg MH, Barouch DH, Sodroski J, Letvin NL. Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope. Journal of Virology. 78: 13901-10. PMID 15564498 DOI: 10.1128/Jvi.78.24.13901-13910.2004  0.73
2004 Barouch DH, Letvin NL, Seder RA. The role of cytokine DNAs as vaccine adjuvants for optimizing cellular immune responses Immunological Reviews. 202: 266-274. PMID 15546399 DOI: 10.1111/j.0105-2896.2004.00200.x  0.637
2004 Sumida SM, McKay PF, Truitt DM, Kishko MG, Arthur JC, Seaman MS, Jackson SS, Gorgone DA, Lifton MA, Letvin NL, Barouch DH. Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines. The Journal of Clinical Investigation. 114: 1334-42. PMID 15520866 DOI: 10.1172/Jci22608  0.636
2004 Lemckert AA, Goudsmit J, Barouch DH. Challenges in the search for an HIV vaccine. European Journal of Epidemiology. 19: 513-6. PMID 15330122 DOI: 10.1023/B:Ejep.0000032423.87658.68  0.509
2004 Barouch DH, Truitt DM, Letvin NL. Expression kinetics of the interleukin-2/immunoglobulin (IL-2/Ig) plasmid cytokine adjuvant Vaccine. 22: 3092-3097. PMID 15297060 DOI: 10.1016/j.vaccine.2004.01.065  0.566
2004 Peyerl FW, Barouch DH, Letvin NL. Structural constraints on viral escape from HIV- and SIV-specific cytotoxic T-lymphocytes. Viral Immunology. 17: 144-51. PMID 15279695 DOI: 10.1089/0882824041310658  0.747
2004 Santra S, Barouch DH, Korioth-Schmitz B, Lord CI, Krivulka GR, Yu F, Beddall MH, Gorgone DA, Lifton MA, Miura A, Philippon V, Manson K, Markham PD, Parrish J, Kuroda MJ, et al. Recombinant poxvirus boosting of DNA-primed rhesus monkeys augments peak but not memory T lymphocyte responses. Proceedings of the National Academy of Sciences of the United States of America. 101: 11088-93. PMID 15258286 DOI: 10.1073/Pnas.0401954101  0.657
2004 Barouch DH, Letvin NL. HIV escape from cytotoxic T lymphocytes: A potential hurdle for vaccines? Lancet. 364: 10-11. PMID 15234837 DOI: 10.1016/S0140-6736(04)16609-9  0.565
2004 Barouch DH, Pau MG, Custers JH, Koudstaal W, Kostense S, Havenga MJ, Truitt DM, Sumida SM, Kishko MG, Arthur JC, Korioth-Schmitz B, Newberg MH, Gorgone DA, Lifton MA, Panicali DL, et al. Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity. Journal of Immunology (Baltimore, Md. : 1950). 172: 6290-7. PMID 15128818 DOI: 10.4049/Jimmunol.172.10.6290  0.597
2004 McKay PF, Barouch DH, Santra S, Sumida SM, Jackson SS, Gorgone DA, Lifton MA, Letvin NL. Recruitment of different subsets of antigen-presenting cells selectively modulates DNA vaccine-elicited CD4+ and CD8+ T lymphocyte responses European Journal of Immunology. 34: 1011-1020. PMID 15048711 DOI: 10.1002/eji.200324840  0.606
2004 Sumida SM, Truitt DM, Kishko MG, Arthur JC, Jackson SS, Gorgone DA, Lifton MA, Koudstaal W, Pau MG, Kostense S, Havenga MJ, Goudsmit J, Letvin NL, Barouch DH. Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. Journal of Virology. 78: 2666-73. PMID 14990686 DOI: 10.1128/Jvi.78.6.2666-2673.2004  0.604
2003 Peyerl FW, Barouch DH, Yeh WW, Bazick HS, Kunstman J, Kunstman KJ, Wolinsky SM, Letvin NL. Simian-human immunodeficiency virus escape from cytotoxic T-lymphocyte recognition at a structurally constrained epitope. Journal of Virology. 77: 12572-8. PMID 14610180 DOI: 10.1128/JVI.77.23.12572-12578.2003  0.738
2003 Mascola JR, Lewis MG, VanCott TC, Stiegler G, Katinger H, Seaman M, Beaudry K, Barouch DH, Korioth-Schmitz B, Krivulka G, Sambor A, Welcher B, Douek DC, Montefiori DC, Shiver JW, et al. Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies. Journal of Virology. 77: 10348-56. PMID 12970419 DOI: 10.1128/JVI.77.19.10348-10356.2003  0.587
2003 Subbramanian RA, Kuroda MJ, Charini WA, Barouch DH, Costantino C, Santra S, Schmitz JE, Martin KL, Lifton MA, Gorgone DA, Shiver JW, Letvin NL. Magnitude and diversity of cytotoxic-T-lymphocyte responses elicited by multiepitope DNA vaccination in rhesus monkeys. Journal of Virology. 77: 10113-8. PMID 12941922 DOI: 10.1128/JVI.77.18.10113-10118.2003  0.677
2003 Barouch DH, McKay PF, Sumida SM, Santra S, Jackson SS, Gorgone DA, Lifton MA, Chakrabarti BK, Xu L, Nabel GJ, Letvin NL. Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. Journal of Virology. 77: 8729-35. PMID 12885892 DOI: 10.1128/Jvi.77.16.8729-8735.2003  0.65
2003 Barouch DH, Kunstman J, Glowczwskie J, Kunstman KJ, Egan MA, Peyerl FW, Santra S, Kuroda MJ, Schmitz JE, Beaudry K, Krivulka GR, Lifton MA, Gorgone DA, Wolinsky SM, Letvin NL. Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys. Journal of Virology. 77: 7367-75. PMID 12805435 DOI: 10.1128/JVI.77.13.7367-7375.2003  0.804
2003 Premenko-Lanier M, Rota PA, Rhodes G, Verhoeven D, Barouch DH, Lerche NW, Letvin NL, Bellini WJ, McChesney MB. DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate. Virology. 307: 67-75. PMID 12667815 DOI: 10.1016/S0042-6822(02)00036-3  0.638
2003 McKay PF, Barouch DH, Schmitz JE, Veazey RS, Gorgone DA, Lifton MA, Williams KC, Letvin NL. Global dysfunction of CD4 T-lymphocyte cytokine expression in simian-human immunodeficiency virus/SIV-infected monkeys is prevented by vaccination Journal of Virology. 77: 4695-4702. PMID 12663776 DOI: 10.1128/JVI.77.8.4695-4702.2003  0.527
2002 Barouch DH, Letvin NL. Viral evolution and challenges in the development of HIV vaccines Vaccine. 20. PMID 12477431 DOI: 10.1016/S0264-410X(02)00390-0  0.672
2002 Santra S, Barouch DH, Kuroda MJ, Schmitz JE, Krivulka GR, Beaudry K, Lord CI, Lifton MA, Wyatt LS, Moss B, Hirsch VM, Letvin NL. Prior vaccination increases the epitopic breadth of the cytotoxic T-lymphocyte response that evolves in rhesus monkeys following a simian-human immunodeficiency virus infection. Journal of Virology. 76: 6376-81. PMID 12021371 DOI: 10.1128/Jvi.76.12.6376-6381.2002  0.672
2002 Letvin NL, Barouch DH, Montefiori DC. Prospects for vaccine protection against HIV-1 infection and AIDS Annual Review of Immunology. 20: 73-99. PMID 11861598 DOI: 10.1146/annurev.immunol.20.081501.094854  0.631
2002 Barouch DH, Kunstman J, Kuroda MJ, Schmitz JE, Santra S, Peyerl FW, Krivulka GR, Beaudry K, Lifton MA, Gorgone DA, Montefiori DC, Lewis MG, Wolinsky SM, Letvin NL. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature. 415: 335-9. PMID 11797012 DOI: 10.1038/415335a  0.802
2002 Barouch DH, Santra S, Tenner-Racz K, Racz P, Kuroda MJ, Schmitz JE, Jackson SS, Lifton MA, Freed DC, Perry HC, Davies ME, Shiver JW, Letvin NL. Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF. Journal of Immunology (Baltimore, Md. : 1950). 168: 562-8. PMID 11777947 DOI: 10.4049/jimmunol.168.2.562  0.597
2002 McKay PF, Schmitz JE, Barouch DH, Kuroda MJ, Lifton MA, Nickerson CE, Gorgone DA, Letvin NL. Vaccine protection against functional CTL abnormalities in simian human immunodeficiency virus-infected rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 168: 332-7. PMID 11751978 DOI: 10.4049/jimmunol.168.1.332  0.56
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