Piet Eikelenboom - Publications

Affiliations: 
Academic Medical Center Amsterdam, Amsterdam, Netherlands 
Area:
Neurology
Website:
http://www.psyfar.nl/tijdschrift/auteurs/auteurs_item/t/eikelenboom_p

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Carlier A, Boers K, Veerhuis R, Bouckaert F, Sienaert P, Eikelenboom P, Vandenbulcke M, Stek ML, van Exel E, Dols A, Rhebergen D. S100 calcium-binding protein B in older patients with depression treated with electroconvulsive therapy. Psychoneuroendocrinology. 110: 104414. PMID 31493698 DOI: 10.1016/J.Psyneuen.2019.104414  0.316
2019 Carlier A, Berkhof JG, Rozing M, Bouckaert F, Sienaert P, Eikelenboom P, Veerhuis R, Vandenbulcke M, Berkhof J, Stek ML, Rhebergen D, Dols A, Exel EV. Inflammation and remission in older patients with depression treated with electroconvulsive therapy; findings from the MODECT study. Journal of Affective Disorders. 256: 509-516. PMID 31279250 DOI: 10.1016/J.Jad.2019.06.040  0.305
2014 Mulder SD, Nielsen HM, Blankenstein MA, Eikelenboom P, Veerhuis R. Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro. Glia. 62: 493-503. PMID 24446231 DOI: 10.1002/glia.22619  0.337
2012 Richard E, Schmand B, Eikelenboom P, Westendorp RG, Van Gool WA. The Alzheimer myth and biomarker research in dementia. Journal of Alzheimer's Disease : Jad. 31: S203-9. PMID 22810091 DOI: 10.3233/Jad-2012-112216  0.38
2012 Ligthart SA, Richard E, Fransen NL, Eurelings LS, Beem L, Eikelenboom P, van Gool WA, Moll van Charante EP. Association of vascular factors with apathy in community-dwelling elderly individuals. Archives of General Psychiatry. 69: 636-42. PMID 22664551 DOI: 10.1001/Archgenpsychiatry.2011.1858  0.313
2012 Eikelenboom P, Hoozemans JJ, Veerhuis R, van Exel E, Rozemuller AJ, van Gool WA. Whether, when and how chronic inflammation increases the risk of developing late-onset Alzheimer's disease. Alzheimer's Research & Therapy. 4: 15. PMID 22647384 DOI: 10.1186/Alzrt118  0.451
2012 Schmand B, Eikelenboom P, van Gool WA. Value of diagnostic tests to predict conversion to Alzheimer's disease in young and old patients with amnestic mild cognitive impairment. Journal of Alzheimer's Disease : Jad. 29: 641-8. PMID 22297644 DOI: 10.3233/Jad-2012-111703  0.358
2012 Eikelenboom P, van Exel E, Veerhuis R, Rozemuller AJ, van Gool WA, Hoozemans JJ. Innate immunity and the etiology of late-onset Alzheimer's disease. Neuro-Degenerative Diseases. 10: 271-3. PMID 22261470 DOI: 10.1159/000334287  0.412
2011 Hoozemans JJ, Rozemuller AJ, van Haastert ES, Eikelenboom P, van Gool WA. Neuroinflammation in Alzheimer's disease wanes with age. Journal of Neuroinflammation. 8: 171. PMID 22152162 DOI: 10.1186/1742-2094-8-171  0.446
2011 Munster BC, Aronica E, Zwinderman AH, Eikelenboom P, Cunningham C, Rooij SE. Neuroinflammation in delirium: a postmortem case-control study. Rejuvenation Research. 14: 615-22. PMID 21978081 DOI: 10.1089/Rej.2011.1185  0.354
2011 Schmand B, Eikelenboom P, van Gool WA. Value of neuropsychological tests, neuroimaging, and biomarkers for diagnosing Alzheimer's disease in younger and older age cohorts. Journal of the American Geriatrics Society. 59: 1705-10. PMID 21883100 DOI: 10.1111/J.1532-5415.2011.03539.X  0.382
2011 Witlox J, Kalisvaart KJ, de Jonghe JF, Verwey NA, van Stijn MF, Houdijk AP, Traast HS, MacLullich AM, van Gool WA, Eikelenboom P. Cerebrospinal fluid β-amyloid and tau are not associated with risk of delirium: a prospective cohort study in older adults with hip fracture. Journal of the American Geriatrics Society. 59: 1260-7. PMID 21718268 DOI: 10.1111/J.1532-5415.2011.03482.X  0.305
2011 Eikelenboom P, Veerhuis R, van Exel E, Hoozemans JJ, Rozemuller AJ, van Gool WA. The early involvement of the innate immunity in the pathogenesis of late-onset Alzheimer's disease: neuropathological, epidemiological and genetic evidence. Current Alzheimer Research. 8: 142-50. PMID 21345167 DOI: 10.2174/156720511795256080  0.439
2011 Hoozemans JJ, Veerhuis R, Rozemuller JM, Eikelenboom P. Soothing the inflamed brain: effect of non-steroidal anti-inflammatory drugs on Alzheimer's disease pathology. Cns & Neurological Disorders Drug Targets. 10: 57-67. PMID 21143138 DOI: 10.2174/187152711794488665  0.462
2011 Oudega ML, van Exel E, Wattjes MP, Comijs HC, Scheltens P, Barkhof F, Eikelenboom P, de Craen AJ, Beekman AT, Stek ML. White matter hyperintensities, medial temporal lobe atrophy, cortical atrophy, and response to electroconvulsive therapy in severely depressed elderly patients. The Journal of Clinical Psychiatry. 72: 104-12. PMID 20816035 DOI: 10.4088/Jcp.08M04989Blu  0.319
2010 Richard E, Carrano A, Hoozemans JJ, van Horssen J, van Haastert ES, Eurelings LS, de Vries HE, Thal DR, Eikelenboom P, van Gool WA, Rozemuller AJ. Characteristics of dyshoric capillary cerebral amyloid angiopathy. Journal of Neuropathology and Experimental Neurology. 69: 1158-67. PMID 20940625 DOI: 10.1097/Nen.0B013E3181Fab558  0.397
2010 Richard E, van Gool WA, Hoozemans JJ, van Haastert ES, Eikelenboom P, Rozemuller AJ, van de Berg WD. Morphometric changes in the cortical microvascular network in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 22: 811-8. PMID 20858968 DOI: 10.3233/Jad-2010-100849  0.381
2010 Eurelings LS, Richard E, Carrano A, Eikelenboom P, van Gool WA, Rozemuller AJ. Dyshoric capillary cerebral amyloid angiopathy mimicking Creutzfeldt-Jakob disease. Journal of the Neurological Sciences. 295: 131-4. PMID 20537354 DOI: 10.1016/J.Jns.2010.04.020  0.407
2010 Kloppenborg RP, Richard E, Sprengers ME, Troost D, Eikelenboom P, Nederkoorn PJ. Steroid responsive encephalopathy in cerebral amyloid angiopathy: a case report and review of evidence for immunosuppressive treatment. Journal of Neuroinflammation. 7: 18. PMID 20214781 DOI: 10.1186/1742-2094-7-18  0.368
2010 Eikelenboom P, van Exel E, Hoozemans JJ, Veerhuis R, Rozemuller AJ, van Gool WA. Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer's disease. Neuro-Degenerative Diseases. 7: 38-41. PMID 20160456 DOI: 10.1159/000283480  0.451
2010 Carrano A, Richard E, Hoozemans J, van Horssen J, van Haastert E, de Vries E, Eikelenboom P, van Gool W, Rozemuller A. P1-209: Capillary cerebral amyloid angiopathy with dyshoric changes: Clinical and pathological characteristics Alzheimer's & Dementia. 6: S234-S234. DOI: 10.1016/J.Jalz.2010.05.760  0.331
2010 Mulder SD, Nielsen HM, Eikelenboom P, Veerhuis R. P2-250: Amyloid-associated proteins differentially modulate Aβ1-42 uptake in primary human microglia and astrocytes Alzheimer's & Dementia. 6: S387-S387. DOI: 10.1016/J.Jalz.2010.05.1299  0.36
2009 van Exel E, Eikelenboom P, Comijs H, Frölich M, Smit JH, Stek ML, Scheltens P, Eefsting JE, Westendorp RG. Vascular factors and markers of inflammation in offspring with a parental history of late-onset Alzheimer disease. Archives of General Psychiatry. 66: 1263-70. PMID 19884614 DOI: 10.1001/Archgenpsychiatry.2009.146  0.378
2009 Hoozemans JJ, van Haastert ES, Nijholt DA, Rozemuller AJ, Eikelenboom P, Scheper W. The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus. The American Journal of Pathology. 174: 1241-51. PMID 19264902 DOI: 10.2353/Ajpath.2009.080814  0.432
2009 Eikelenboom P, Veerhuis R, Familian A, van Gool W, Rozemuller J. The neuroinflammatory response in plaques and amyloid angiopathy in Alzheimer's disease Journal of the Neurological Sciences. 283: 273-274. DOI: 10.1016/j.jns.2009.02.132  0.352
2008 Hoozemans JJ, Rozemuller JM, van Haastert ES, Veerhuis R, Eikelenboom P. Cyclooxygenase-1 and -2 in the different stages of Alzheimer's disease pathology. Current Pharmaceutical Design. 14: 1419-27. PMID 18537664 DOI: 10.2174/138161208784480171  0.479
2008 Eikelenboom P, Veerhuis R, Familian A, Hoozemans JJ, van Gool WA, Rozemuller AJ. Neuroinflammation in plaque and vascular beta-amyloid disorders: clinical and therapeutic implications. Neuro-Degenerative Diseases. 5: 190-3. PMID 18322387 DOI: 10.1159/000113699  0.438
2007 Scheper W, Hoozemans JJ, Hoogenraad CC, Rozemuller AJ, Eikelenboom P, Baas F. Rab6 is increased in Alzheimer's disease brain and correlates with endoplasmic reticulum stress. Neuropathology and Applied Neurobiology. 33: 523-32. PMID 17573808 DOI: 10.1111/J.1365-2990.2007.00846.X  0.44
2007 Familian A, Eikelenboom P, Veerhuis R. Minocycline does not affect amyloid beta phagocytosis by human microglial cells. Neuroscience Letters. 416: 87-91. PMID 17317005 DOI: 10.1016/J.Neulet.2007.01.052  0.444
2007 Lemstra AW, Groen in't Woud JC, Hoozemans JJ, van Haastert ES, Rozemuller AJ, Eikelenboom P, van Gool WA. Microglia activation in sepsis: a case-control study. Journal of Neuroinflammation. 4: 4. PMID 17224051 DOI: 10.1186/1742-2094-4-4  0.319
2006 Eikelenboom P, Veerhuis R, Scheper W, Rozemuller AJ, van Gool WA, Hoozemans JJ. The significance of neuroinflammation in understanding Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 113: 1685-95. PMID 17036175 DOI: 10.1007/S00702-006-0575-6  0.46
2006 Hoozemans JJ, Chafekar SM, Baas F, Eikelenboom P, Scheper W. Always around, never the same: pathways of amyloid beta induced neurodegeneration throughout the pathogenic cascade of Alzheimer's disease. Current Medicinal Chemistry. 13: 2599-605. PMID 17017913 DOI: 10.2174/092986706778201585  0.363
2006 Kerssens CJ, Pijnenburg YA, Schouws S, Eikelenboom P, van Tilburg W. [The development of psychotic symptoms in later life: late-onset schizophrenia or frontotemporal dementia? A case study]. Tijdschrift Voor Psychiatrie. 48: 739-44. PMID 17007480  0.494
2006 Kerssens CJ, Pijnenburg YA, Schouws S, Eikelenboom P, van Tilburg W. [Late-onset schizophrenia: is it a dementia nonpraecox? Review article with advice on differential diagnosis]. Tijdschrift Voor Psychiatrie. 48: 717-27. PMID 17007477  0.492
2006 Coppus A, Evenhuis H, Verberne GJ, Visser F, van Gool P, Eikelenboom P, van Duijin C. Dementia and mortality in persons with Down's syndrome. Journal of Intellectual Disability Research : Jidr. 50: 768-77. PMID 16961706 DOI: 10.1111/J.1365-2788.2006.00842.X  0.368
2006 Hoozemans JJ, Stieler J, van Haastert ES, Veerhuis R, Rozemuller AJ, Baas F, Eikelenboom P, Arendt T, Scheper W. The unfolded protein response affects neuronal cell cycle protein expression: implications for Alzheimer's disease pathogenesis. Experimental Gerontology. 41: 380-6. PMID 16564150 DOI: 10.1016/J.Exger.2006.01.013  0.388
2006 Hoozemans JJ, Veerhuis R, Rozemuller JM, Eikelenboom P. Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 24: 157-65. PMID 16384684 DOI: 10.1016/J.Ijdevneu.2005.11.001  0.451
2006 Familian A, Boshuizen RS, Eikelenboom P, Veerhuis R. Inhibitory effect of minocycline on amyloid beta fibril formation and human microglial activation. Glia. 53: 233-40. PMID 16220550 DOI: 10.1002/Glia.20268  0.412
2006 Veerhuis R, Familian A, Eikelenboom P. P4-307: Minocycline attenuates the amyloid-β (Aβ) mediated activation of human microglia without affecting microglial Aβ phagocytosis in vitro Alzheimer's & Dementia. 2: S607-S607. DOI: 10.1016/J.Jalz.2006.05.2048  0.372
2005 Rozemuller AJ, van Gool WA, Eikelenboom P. The neuroinflammatory response in plaques and amyloid angiopathy in Alzheimer's disease: therapeutic implications. Current Drug Targets. Cns and Neurological Disorders. 4: 223-33. PMID 15975026 DOI: 10.2174/1568007054038229  0.478
2005 Hoozemans JJ, Veerhuis R, Van Haastert ES, Rozemuller JM, Baas F, Eikelenboom P, Scheper W. The unfolded protein response is activated in Alzheimer's disease. Acta Neuropathologica. 110: 165-72. PMID 15973543 DOI: 10.1007/S00401-005-1038-0  0.441
2005 Veerhuis R, Boshuizen RS, Morbin M, Mazzoleni G, Hoozemans JJ, Langedijk JP, Tagliavini F, Langeveld JP, Eikelenboom P. Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q. Neurobiology of Disease. 19: 273-82. PMID 15837583 DOI: 10.1016/J.Nbd.2005.01.005  0.352
2004 Blasko I, Stampfer-Kountchev M, Robatscher P, Veerhuis R, Eikelenboom P, Grubeck-Loebenstein B. How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes. Aging Cell. 3: 169-76. PMID 15268750 DOI: 10.1111/J.1474-9728.2004.00101.X  0.424
2004 Bate C, Veerhuis R, Eikelenboom P, Williams A. Microglia kill amyloid-beta1-42 damaged neurons by a CD14-dependent process. Neuroreport. 15: 1427-30. PMID 15194867 DOI: 10.1097/01.Wnr.0000132203.76836.16  0.35
2004 Eikelenboom P, van Gool WA. Neuroinflammatory perspectives on the two faces of Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 111: 281-94. PMID 14991455 DOI: 10.1007/S00702-003-0055-1  0.469
2004 Veerhuis R, Boshuizen RS, Morbin M, Hoozemans JJ, Eikelenboom P. P3-383 Microglial activation by prion peptides is enhanced by amyloid associated factors SAP and C1Q that increase PRP fibrillarity Neurobiology of Aging. 25: S464. DOI: 10.1016/S0197-4580(04)81532-X  0.303
2004 Hoozemans J, Veerhuis R, Rozemuller A, Arendt T, Eikelenboom P. P3-216 Neuronal immunoreactivity for COX-2 and phosphorylation of PRB precede P38 MAPK activation and neurofibrillary changes in AD temporal cortex Neurobiology of Aging. 25: S416. DOI: 10.1016/S0197-4580(04)81366-6  0.32
2003 Bate C, Veerhuis R, Eikelenboom P, Williams A. Neurones treated with cyclo-oxygenase-1 inhibitors are resistant to amyloid-beta1-42. Neuroreport. 14: 2099-103. PMID 14600505 DOI: 10.1097/01.Wnr.0000097050.56589.D8  0.357
2003 van Gool WA, Aisen PS, Eikelenboom P. Anti-inflammatory therapy in Alzheimer's disease: is hope still alive? Journal of Neurology. 250: 788-92. PMID 12883918 DOI: 10.1007/S00415-003-1146-5  0.302
2003 Hoozemans JJ, Veerhuis R, Rozemuller AJ, Eikelenboom P. Non-steroidal anti-inflammatory drugs and cyclooxygenase in Alzheimer's disease. Current Drug Targets. 4: 461-8. PMID 12866660 DOI: 10.2174/1389450033490902  0.4
2003 Veerhuis R, Van Breemen MJ, Hoozemans JM, Morbin M, Ouladhadj J, Tagliavini F, Eikelenboom P. Amyloid beta plaque-associated proteins C1q and SAP enhance the Abeta1-42 peptide-induced cytokine secretion by adult human microglia in vitro. Acta Neuropathologica. 105: 135-44. PMID 12536224 DOI: 10.1007/S00401-002-0624-7  0.447
2003 Lemstra AW, Eikelenboom P, van Gool WA. The cholinergic deficiency syndrome and its therapeutic implications. Gerontology. 49: 55-60. PMID 12457052 DOI: 10.1159/000066508  0.373
2002 Hoozemans JJ, Veerhuis R, Rozemuller AJ, Eikelenboom P. The pathological cascade of Alzheimer's disease: the role of inflammation and its therapeutic implications. Drugs of Today (Barcelona, Spain : 1998). 38: 429-43. PMID 12532179 DOI: 10.1358/Dot.2002.38.6.678350  0.46
2002 Mulder C, Schoonenboom SN, Wahlund LO, Scheltens P, van Kamp GJ, Veerhuis R, Hack CE, Blomberg M, Schutgens RB, Eikelenboom P. CSF markers related to pathogenetic mechanisms in Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 109: 1491-8. PMID 12486489 DOI: 10.1007/s00702-002-0763-y  0.334
2002 Nandoe RD, Scheltens P, Eikelenboom P. Head trauma and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 4: 303-8. PMID 12446932 DOI: 10.3233/Jad-2002-4405  0.397
2002 Eikelenboom P, Bate C, Van Gool WA, Hoozemans JJ, Rozemuller JM, Veerhuis R, Williams A. Neuroinflammation in Alzheimer's disease and prion disease. Glia. 40: 232-9. PMID 12379910 DOI: 10.1002/Glia.10146  0.483
2002 Hoozemans JJ, Veerhuis R, Janssen I, van Elk EJ, Rozemuller AJ, Eikelenboom P. The role of cyclo-oxygenase 1 and 2 activity in prostaglandin E(2) secretion by cultured human adult microglia: implications for Alzheimer's disease. Brain Research. 951: 218-26. PMID 12270500 DOI: 10.1016/S0006-8993(02)03164-5  0.389
2002 Hoozemans JJ, Brückner MK, Rozemuller AJ, Veerhuis R, Eikelenboom P, Arendt T. Cyclin D1 and cyclin E are co-localized with cyclo-oxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex. Journal of Neuropathology and Experimental Neurology. 61: 678-88. PMID 12152783 DOI: 10.1093/Jnen/61.8.678  0.378
2002 Eikelenboom P, Hoogendijk WJ, Jonker C, van Tilburg W. Immunological mechanisms and the spectrum of psychiatric syndromes in Alzheimer's disease. Journal of Psychiatric Research. 36: 269-80. PMID 12127594 DOI: 10.1016/S0022-3956(02)00006-7  0.728
2002 Veerhuis R, Hoozemans JJ, Janssen I, Boshuizen RS, Langeveld JP, Eikelenboom P. Adult human microglia secrete cytokines when exposed to neurotoxic prion protein peptide: no intermediary role for prostaglandin E2. Brain Research. 925: 195-203. PMID 11792368 DOI: 10.1016/S0006-8993(01)03273-5  0.308
2001 Hoozemans JJ, Rozemuller AJ, Veerhuis R, Eikelenboom P. Immunological aspects of alzheimer's disease: therapeutic implications. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 15: 325-37. PMID 11437695 DOI: 10.2165/00063030-200115050-00004  0.47
2001 Hoogendijk WJ, Meynen G, Feenstra MG, Eikelenboom P, Kamphorst W, Swaab DF. [Increased activity of stress-regulating systems in Alzheimer disease]. Tijdschrift Voor Gerontologie En Geriatrie. 32: 17-23. PMID 11293840  0.737
2001 Hoozemans JJM, Veerhuis R, Janssen I, Rozemuller AJM, Eikelenboom P. Interleukin-1β induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: Implications for Alzheimer's disease Experimental Gerontology. 36: 559-570. PMID 11250126 DOI: 10.1016/S0531-5565(00)00226-6  0.35
2001 Hoozemans JJM, Rozemuller AJM, Janssen I, De Groot CJA, Veerhuis R, Eikelenboom P. Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain Acta Neuropathologica. 101: 2-8. PMID 11194936 DOI: 10.1007/S004010000251  0.44
2000 Hoogendijk WJ, Meynen G, Eikelenboom P, Swaab DF. Brain alterations in depression. Acta Neuropsychiatrica. 12: 54-8. PMID 26976759 DOI: 10.1017/S0924270800035717  0.733
2000 Blasko I, Veerhuis R, Stampfer-Kountchev M, Saurwein-Teissl M, Eikelenboom P, Grubeck-Loebenstein B. Costimulatory effects of interferon-γ and interleukin-1β or tumor necrosis factor α on the synthesis of Aβ1-40 and Aβ1-42 by human astrocytes Neurobiology of Disease. 7: 682-689. PMID 11114266 DOI: 10.1006/Nbdi.2000.0321  0.366
2000 Rozemuller AJ, Eikelenboom P, Theeuwes JW, Jansen Steur EN, de Vos RA. Activated microglial cells and complement factors are unrelated to cortical Lewy bodies. Acta Neuropathologica. 100: 701-8. PMID 11078223 DOI: 10.1007/s004010000225  0.356
2000 van Gool WA, Eikelenboom P. The two faces of Alzheimer's disease. Journal of Neurology. 247: 500-5. PMID 10993489  0.362
2000 Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S, Griffin WS, Hampel H, Hull M, et al. Inflammation and Alzheimer's disease. Neurobiology of Aging. 21: 383-421. PMID 10858586 DOI: 10.1016/S0197-4580(00)00124-X  0.465
2000 Eikelenboom P, Rozemuller AJ, Hoozemans JJ, Veerhuis R, van Gool WA. Neuroinflammation and Alzheimer disease: clinical and therapeutic implications. Alzheimer Disease and Associated Disorders. 14: S54-61. PMID 10850731 DOI: 10.1097/00002093-200000001-00009  0.457
2000 Van Waarde JA, Timmer LSH, Eikelenboom P, Stam F, Perquin L, Stek ML, Harms HH, De Reus R, Pootjes YG, Rooze HAH. Successful treatment after stubborn resistance of an elderly woman [1] (multiple letters) | Succesvolle behandeling na grimmig verzet van een bejaarde vrouw Nederlands Tijdschrift Voor Geneeskunde. 144: 821-822. PMID 10800554  0.515
2000 Arends YM, Duyckaerts C, Rozemuller JM, Eikelenboom P, Hauw JJ. Microglia, amyloid and dementia in alzheimer disease. A correlative study. Neurobiology of Aging. 21: 39-47. PMID 10794847 DOI: 10.1016/S0197-4580(00)00094-4  0.419
2000 Eikelenboom P, Duyckaert C, Williams AE, Rozemuller AJM. Neuroinflammation and Alzheimer's disease: Relationship between pathogenic mechanisms and clinical expression Neurobiology of Aging. 21: 285. DOI: 10.1016/S0197-4580(00)83234-0  0.371
2000 Duyckaerts C, Arends YM, He Y, Rozemuller AJ, Eikelenboom P, Hauw J, Piette F. Clinicopathological data on the progression of Alzheimer disease lesions in the cerebral cortex Neurobiology of Aging. 21: 265. DOI: 10.1016/S0197-4580(00)83146-2  0.332
2000 Veerhuis R, Janssen I, Van Muiswinkel FL, Eikelenboom P. Involvement of serum amyloid P component and C-reactive protein in the pathogenesis of Alzheimer's disease Neurobiology of Aging. 21: 265. DOI: 10.1016/S0197-4580(00)83145-0  0.42
2000 Hoozemans JJ, Janssen I, Veerhuis R, Eikelenboom P. Cyclooxygenase expression in microglia and neurons in Alzheimer's disease brain Neurobiology of Aging. 21: 119. DOI: 10.1016/S0197-4580(00)82335-0  0.407
2000 Blasko I, Stampfer M, Eikelenboom P, Grubeck-Loebestein B. Cytokines stimulate primary human astrocytes to produce amyloid beta Neurobiology of Aging. 21: 114. DOI: 10.1016/S0197-4580(00)82313-1  0.309
2000 Hoogendijk WJG, Meynen G, Eikelenboom P, Swaab DF. Brain alterations in depression Acta Neuropsychiatrica. 12: 54-58.  0.618
1999 Veerhuis R, Janssen I, De Groot CJA, Van Muiswinkel FL, Hack CE, Eikelenboom P. Cytokines associated with amyloid plaques in Alzheimer's disease brain stimulate human glial and neuronal cell cultures to secrete early complement proteins, but not C1-inhibitor Experimental Neurology. 160: 289-299. PMID 10630213 DOI: 10.1006/Exnr.1999.7199  0.344
1999 Eikelenboom P, Hoogendijk WJ. Do delirium and Alzheimer's dementia share specific pathogenetic mechanisms? Dementia and Geriatric Cognitive Disorders. 10: 319-24. PMID 10473931 DOI: 10.1159/000017162  0.628
1999 Eikelenboom P, Veerhuis R. The importance of inflammatory mechanisms for the development of Alzheimer's disease Experimental Gerontology. 34: 453-461. PMID 10433400 DOI: 10.1016/S0531-5565(99)00022-4  0.453
1999 Van Muiswinkel FL, Raupp SFA, De Vos NM, Smits HA, Verhoef J, Eikelenboom P, Nottet HSLM. The amino-terminus of the amyloid-β protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages Journal of Neuroimmunology. 96: 121-130. PMID 10227431 DOI: 10.1016/S0165-5728(99)00019-3  0.332
1999 Hoogendijk WJ, Feenstra MG, Botterblom MH, Gilhuis J, Sommer IE, Kamphorst W, Eikelenboom P, Swaab DF. Increased activity of surviving locus ceruleus neurons in Alzheimer's disease. Annals of Neurology. 45: 82-91. PMID 9894881 DOI: 10.1002/1531-8249(199901)45:1<82::Aid-Art14>3.0.Co;2-T  0.695
1999 Hoogendijk WJ, Sommer IE, Pool CW, Kamphorst W, Hofman MA, Eikelenboom P, Swaab DF. Lack of association between depression and loss of neurons in the locus coeruleus in Alzheimer disease. Archives of General Psychiatry. 56: 45-51. PMID 9892255 DOI: 10.1001/Archpsyc.56.1.45  0.678
1998 Eikelenboom P, Rozemuller JM, Van Muiswinkel FL. Inflammation and Alzheimer's disease: Relationships between pathogenic mechanisms and clinical expression Experimental Neurology. 154: 89-98. PMID 9875271 DOI: 10.1006/Exnr.1998.6920  0.475
1998 Veerhuis R, Janssen I, Hoozemans JJM, De Groot CJA, Hack CE, Eikelenboom P. Complement C1-inhibitor expression in Alzheimer's disease Acta Neuropathologica. 96: 287-296. PMID 9754962 DOI: 10.1007/S004010050896  0.391
1998 McBride PA, Wilson MI, Eikelenboom P, Tunstall A, Bruce ME. Heparan sulfate proteoglycan is associated with amyloid plaques and neuroanatomically targeted PrP pathology throughout the incubation period of scrapie-infected mice. Experimental Neurology. 149: 447-54. PMID 9500966 DOI: 10.1006/Exnr.1997.6740  0.417
1998 VERBEEK MM, EIKELENBOOM P, DE WAAL RM. Amyloid Formation in Senile Plaques and Congophil-ic Angiopathy Journal of Neuropathology and Experimental Neurology. 57: 97-98. DOI: 10.1097/00005072-199801000-00013  0.333
1997 Verbeek MM, Eikelenboom P, De Waal RMW. Differences between the pathogenesis of senile plaques and congophilic angiopathy in alzheimer disease Journal of Neuropathology and Experimental Neurology. 56: 751-761. PMID 9210871 DOI: 10.1097/00005072-199756070-00001  0.447
1996 Eikelenboom P, Veerhuis R. The role of complement and activated microglia in the pathogenesis of Alzheimer's disease Neurobiology of Aging. 17: 673-680. PMID 8892339 DOI: 10.1016/0197-4580(96)00108-X  0.439
1996 Van Muiswinkel FL, Eikelenboom P. Do nonsteroidal anti-inflammatory drugs have a protective effect against dementia? Drugs and Aging. 9: 1-7. PMID 8818581 DOI: 10.2165/00002512-199609010-00001  0.383
1996 Van Muiswinkel FL, Veerhuis R, Eikelenboom P. Amyloid β protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity Journal of Neurochemistry. 66: 2468-2476. PMID 8632171 DOI: 10.1046/J.1471-4159.1996.66062468.X  0.35
1996 Hoogendijkt W, Sommers I, Eikelenboom P, Pool C, Swaab D. 470 The locus coeruleus in Alzheimer's Disease: the relation between cell death and depression Neurobiology of Aging. 17: S117. DOI: 10.1016/S0197-4580(96)80472-6  0.527
1995 Veerhuis R, Janssen I, Hack CE, Eikelenboom P. Early complement components in Alzheimer's disease brains Acta Neuropathologica. 91: 53-60. PMID 8773146 DOI: 10.1007/S004019570001  0.35
1995 Zhan SS, Veerhuis R, Kamphorst W, Eikelenboom P. Distribution of beta amyloid associated proteins in plaques in Alzheimer's disease and in the non-demented elderly Neurodegeneration. 4: 291-297. PMID 8581561 DOI: 10.1016/1055-8330(95)90018-7  0.403
1995 Veerhuis R, van der Valk P, Janssen I, Zhan SS, Eikelenboom P, Van Nostrand WE. Complement activation in amyloid plaques in Alzheimer's disease brains does not proceed further than C3 Virchows Archiv. 426: 603-610. PMID 7655742 DOI: 10.1007/Bf00192116  0.432
1995 Zhan SS, Kamphorst W, Van Nostrand WE, Eikelenboom P. Distribution of neuronal growth-promoting factors and cytoskeletal proteins in altered neurites in Alzheimer's disease and non-demented elderly Acta Neuropathologica. 89: 356-362. PMID 7610767 DOI: 10.1007/Bf00309629  0.465
1994 Eikelenboom P, Zhan SS, van Gool WA, Allsop D. Inflammatory mechanisms in Alzheimer's disease. Trends in Pharmacological Sciences. 15: 447-50. PMID 7886816 DOI: 10.1016/0165-6147(94)90057-4  0.469
1994 Maat-Schieman ML, Rozemuller AJ, van Duinen SG, Haan J, Eikelenboom P, Roos RA. Microglia in diffuse plaques in hereditary cerebral hemorrhage with amyloidosis (Dutch). An immunohistochemical study. Journal of Neuropathology and Experimental Neurology. 53: 483-91. PMID 7521904 DOI: 10.1097/00005072-199409000-00007  0.4
1994 Eikelenboom P, Zhan SS, Kamphorst W, van der Valk P, Rozemuller JM. Cellular and substrate adhesion molecules (integrins) and their ligands in cerebral amyloid plaques in Alzheimer's disease Virchows Archiv. 424: 421-427. PMID 7515758 DOI: 10.1007/Bf00190565  0.384
1994 Veerhuis R, Janssen I, Zahn S, Eikelenboom P. Complement components in Alzheimer's disease brain Journal of Neuroimmunology. 54: 203. DOI: 10.1016/0165-5728(94)90566-5  0.41
1993 Rozemuller AJM, Roos RAC, Bots GTAM, Kamphorst W, Eikelenboom P, Van Nostrand WE. Distribution of β/A4 protein and amyloid precursor protein in hereditary cerebral hemorrhage with amyloidosis-Dutch type and Alzheimer's disease American Journal of Pathology. 142: 1449-1457. PMID 7684195  0.321
1992 Gollin PA, Kalaria RN, Eikelenboom P, Rozemuller A, Perry G. Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease. Neuroreport. 3: 201-3. PMID 1623174 DOI: 10.1097/00001756-199202000-00020  0.308
1992 Rozemuller JM, der^Valk Pv, Eikelenboom P. Activated microglia and cerebral amyloid deposits in alzheimer's disease Research in Immunology. 143: 646-649. PMID 1455057 DOI: 10.1016/0923-2494(92)80050-U  0.457
1992 Eikelenboom P, Hack CE, Kamphorst W, Rozemuller JM. Distribution pattern and functional state of complement proteins and α-antichymotrypsin in cerebral β/A4 deposits in Alzheimer's disease Research in Immunology. 143: 617-620. PMID 1455052 DOI: 10.1016/0923-2494(92)80044-L  0.325
1992 Rozemuller JM, Bots GTAM, Roos RAC, Eikelenboom P. Acute phase proteins but not activated microglial cells are present in parenchymal β A4 deposits in the brains of patients with hereditary cerebral hemorrhage with amyloidosis-Dutch type Neuroscience Letters. 140: 137-140. PMID 1380141 DOI: 10.1016/0304-3940(92)90087-N  0.388
1992 Eikelenboom P, Berkenbosch F, Hack C, Rozemuller J. Neuroimmunological mechanisms in cerebral amyloid formation in Alzheimer's disease Neurobiology of Aging. 13: S86. DOI: 10.1016/0197-4580(92)90467-C  0.343
1991 Rozemuller JM, Abbink JJ, Kamp AM, Stam FC, Hack CE, Eikelenboom P. Distribution pattern and functional state of alpha 1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease. A immunohistochemical study with monoclonal antibodies against native and inactivated alpha 1-antichymotrypsin. Acta Neuropathologica. 82: 200-7. PMID 1927277 DOI: 10.1007/Bf00294446  0.672
1991 Eikelenboom P, Rozemuller JM, Kraal G, Stam FC, McBride PA, Bruce ME, Fraser H. Cerebral amyloid plaques in Alzheimer's disease but not in scrapie-affected mice are closely associated with a local inflammatory process. Virchows Archiv. B, Cell Pathology Including Molecular Pathology. 60: 329-36. PMID 1685040 DOI: 10.1007/Bf02899564  0.695
1990 Witting W, Kwa IH, Eikelenboom P, Mirmiran M, Swaab DF. Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease Biological Psychiatry. 27: 563-572. PMID 2322616 DOI: 10.1016/0006-3223(90)90523-5  0.544
1990 Rozemuller JM, Stam FC, Eikelenboom P. Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease. Neuroscience Letters. 119: 75-8. PMID 1711182 DOI: 10.1016/0304-3940(90)90759-3  0.669
1989 Rozemuller JM, Eikelenboom P, Stam FC, Beyreuther K, Masters CL. A4 protein in Alzheimer's disease: primary and secondary cellular events in extracellular amyloid deposition. Journal of Neuropathology and Experimental Neurology. 48: 674-91. PMID 2677252 DOI: 10.1097/00005072-198911000-00009  0.67
1989 Eikelenboom P, Hack CE, Rozemuller JM, Stam FC. Complement activation in amyloid plaques in Alzheimer's dementia. Virchows Archiv. B, Cell Pathology Including Molecular Pathology. 56: 259-62. PMID 2565620 DOI: 10.1007/Bf02890024  0.68
1989 Rozemuller JM, Eikelenboom P, Pals ST, Stam FC. Microglial cells around amyloid plaques in Alzheimer's disease express leucocyte adhesion molecules of the LFA-1 family. Neuroscience Letters. 101: 288-92. PMID 2549464 DOI: 10.1016/0304-3940(89)90547-8  0.659
1989 Mirmiran M, Swaab DF, Witting W, Honnebier MBOM, Van Gool WA, Eikelenboom P. Biological clocks in development, aging and Alzheimer's disease Brain Dysfunction. 2: 57-66.  0.445
1988 Rozemuller JM, Eikelenboom P, Kamphorst W, Stam FC. Lack of evidence for dysfunction of the blood-brain barrier in Alzheimer's disease: an immunohistochemical study. Neurobiology of Aging. 9: 383-91. PMID 3185857 DOI: 10.1016/S0197-4580(88)80085-X  0.673
1987 Eikelenboom P, Scott JR, McBride PA, Rozemuller JM, Bruce ME, Fraser H. No evidence for involvement of plasma proteins or blood-borne cells in amyloid plaque formation in scrapie-affected mice - An immunohistoperoxidase study Virchows Archiv B Cell Pathology Including Molecular Pathology. 53: 251-256. PMID 2890238 DOI: 10.1007/Bf02890250  0.353
1987 Eikelenboom P, Brion J, McBride P, Bruce M. 41. Immunocytochemical and histochemical comparison of amyloid plaques in Alzheimer's disease and mouse scrapie Clinical Neurology and Neurosurgery. 89: 15. DOI: 10.1016/0303-8467(87)90041-2  0.467
1987 Rozemuller J, Eikelenboom P, Stam F. 16. No evidence for blood-brain barrier disorders in Alzheimer's disease Clinical Neurology and Neurosurgery. 89: 6. DOI: 10.1016/0303-8467(87)90016-3  0.652
1986 Rozemuller JM, Eikelenboom P, Stam FC. Role of microglia in plaque formation in senile dementia of the Alzheimer type. An immunohistochemical study. Virchows Archiv. B, Cell Pathology Including Molecular Pathology. 51: 247-54. PMID 2874657 DOI: 10.1007/Bf02899034  0.682
1984 Eikelenboom P, Stam FC. An immunohistochemical study on cerebral vascular and senile plaque amyloid in Alzheimer's dementia. Virchows Archiv. B, Cell Pathology Including Molecular Pathology. 47: 17-25. PMID 6151285 DOI: 10.1007/BF02890185  0.667
1983 Eikelenboom P, Jonker C, Stam FC. [Do immunological factors play a role in the pathogenesis of Alzheimer's disease?]. Tijdschrift Voor Gerontologie En Geriatrie. 14: 181-5. PMID 6606242  0.668
1982 Eikelenboom P, Stam FC. Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study. Acta Neuropathologica. 57: 239-42. PMID 6812382 DOI: 10.1007/Bf00685397  0.661
1978 Eikelenboom P, Nassy JJ, Post J, Versteeg JC, Langevoort HL. The histogenesis of lymph nodes in rat and rabbit. The Anatomical Record. 190: 201-15. PMID 629402 DOI: 10.1002/ar.1091900204  0.671
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