| Year |
Citation |
Score |
| 2023 |
Shimanaka K, Shi B, Brontesi L, Alnakhala H, Jayanthi V, Subramanian K, Ramalingam N, Tripathi A, Dettmer U. Adding hydrophobicity or positive charges to the cytosolic half of the α-synuclein 3-11 helix increases membrane association and S129 phosphorylation. Febs Letters. PMID 37989349 DOI: 10.1002/1873-3468.14773 |
0.758 |
|
| 2023 |
Ramalingam N, Dettmer U. α-Synuclein serine129 phosphorylation - the physiology of pathology. Molecular Neurodegeneration. 18: 84. PMID 37953316 DOI: 10.1186/s13024-023-00680-x |
0.684 |
|
| 2023 |
Ramalingam N, Brontesi L, Jin SX, Selkoe DJ, Dettmer U. Dynamic reversibility of α-synuclein serine-129 phosphorylation is impaired in synucleinopathy models. Embo Reports. e57145. PMID 37870370 DOI: 10.15252/embr.202357145 |
0.746 |
|
| 2023 |
Jin M, Wei Z, Ramalingam N, Xiao M, Xu A, Yu X, Song Q, Liu W, Zhao J, Zhang D, Selkoe DJ, Li S. Activation of β-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms. Molecular Psychiatry. PMID 37365243 DOI: 10.1038/s41380-023-02145-5 |
0.415 |
|
| 2023 |
Ramalingam N, Jin SX, Moors TE, Fonseca-Ornelas L, Shimanaka K, Lei S, Cam HP, Watson AH, Brontesi L, Ding L, Hacibaloglu DY, Jiang H, Choi SJ, Kanter E, Liu L, et al. Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity. Npj Parkinson's Disease. 9: 4. PMID 36646701 DOI: 10.1038/s41531-023-00444-w |
0.727 |
|
| 2023 |
Brontesi L, Imberdis T, Ramalingam N, Dettmer U. The effects of KTKEGV repeat motif and intervening ATVA sequence on α-synuclein solubility and assembly. Journal of Neurochemistry. PMID 36625497 DOI: 10.1111/jnc.15763 |
0.723 |
|
| 2022 |
Tripathi A, Alnakhala H, Terry-Kantor E, Newman A, Liu L, Imberdis T, Fanning S, Nuber S, Ramalingam N, Selkoe D, Dettmer U. Pathogenic mechanisms of cytosolic and membrane-enriched α-synuclein converge on fatty acid homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35086904 DOI: 10.1523/JNEUROSCI.1881-21.2022 |
0.739 |
|
| 2021 |
Kim TE, Newman AJ, Imberdis T, Brontesi L, Tripathi A, Ramalingam N, Fanning S, Selkoe D, Dettmer U. Excess membrane binding of monomeric alpha-, beta-, and gamma-synuclein is invariably associated with inclusion formation and toxicity. Human Molecular Genetics. PMID 34254125 DOI: 10.1093/hmg/ddab188 |
0.773 |
|
| 2021 |
Ramalingam N, Dettmer U. Temperature is a key determinant of alpha- and beta-synuclein membrane interactions in neurons. The Journal of Biological Chemistry. 296: 100271. PMID 33428933 DOI: 10.1016/j.jbc.2021.100271 |
0.723 |
|
| 2020 |
Ho GPH, Ramalingam N, Imberdis T, Wilkie EC, Dettmer U, Selkoe DJ. Upregulation of Cellular Palmitoylation Mitigates α-Synuclein Accumulation and Neurotoxicity. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33103814 DOI: 10.1002/mds.28346 |
0.778 |
|
| 2020 |
Terry-Kantor E, Tripathi A, Imberdis T, LaVoie ZM, Ho GPH, Selkoe D, Fanning S, Ramalingam N, Dettmer U. Rapid Alpha-Synuclein Toxicity in a Neural Cell Model and Its Rescue by a Stearoyl-CoA Desaturase Inhibitor. International Journal of Molecular Sciences. 21. PMID 32707907 DOI: 10.3390/ijms21155193 |
0.737 |
|
| 2019 |
Imberdis T, Negri J, Ramalingam N, Terry-Kantor E, Ho GPH, Fanning S, Stirtz G, Kim TE, Levy OA, Young-Pearse TL, Selkoe D, Dettmer U. Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase. Proceedings of the National Academy of Sciences of the United States of America. PMID 31548371 DOI: 10.1073/Pnas.1903216116 |
0.767 |
|
| 2019 |
Imberdis T, Fanning S, Newman A, Ramalingam N, Dettmer U. Studying α-Synuclein Conformation by Intact-Cell Cross-Linking. Methods in Molecular Biology (Clifton, N.J.). 1948: 77-91. PMID 30771172 DOI: 10.1007/978-1-4939-9124-2_8 |
0.679 |
|
| 2018 |
Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, et al. Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Molecular Cell. PMID 30527540 DOI: 10.1016/J.Molcel.2018.11.028 |
0.744 |
|
| 2018 |
Sun X, Aimé P, Dai D, Ramalingam N, Crary JF, Burke RE, Greene LA, Levy OA. Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease. Experimental Neurology. PMID 29432724 DOI: 10.1016/J.Expneurol.2018.01.015 |
0.357 |
|
| 2017 |
Dettmer U, Ramalingam N, von Saucken VE, Kim TE, Newman AJ, Terry-Kantor E, Nuber S, Ericsson M, Fanning S, Bartels T, Lindquist S, Levy OA, Selkoe D. Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells. Human Molecular Genetics. 26: 3466-3481. PMID 28911198 DOI: 10.1093/hmg/ddx227 |
0.759 |
|
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