Lloyd Greene - Publications

Columbia University, New York, NY 
neuronal death, neural development

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sun X, Jefferson P, Zhou Q, Angelastro JM, Greene LA. Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD. Molecular Cancer Research : McR. PMID 31676720 DOI: 10.1158/1541-7786.MCR-19-0631  0.48
2019 Sun X, Angelastro JM, Merino D, Zhou Q, Siegelin MD, Greene LA. Dominant-negative ATF5 rapidly depletes survivin in tumor cells. Cell Death & Disease. 10: 709. PMID 31551409 DOI: 10.1038/s41419-019-1872-y  0.48
2018 Corona C, Pasini S, Liu J, Amar F, Greene LA, Shelanski ML. Activating Transcription Factor 4 (ATF4) regulates neuronal activity by controlling GABAR trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29875265 DOI: 10.1523/JNEUROSCI.3350-17.2018  0.72
2018 Liu J, Amar F, Corona C, So RWL, Andrews SJ, Nagy PL, Shelanski ML, Greene LA. Brain-Derived Neurotrophic Factor Elevates Activating Transcription Factor 4 (ATF4) in Neurons and Promotes ATF4-Dependent Induction of. Frontiers in Molecular Neuroscience. 11: 62. PMID 29599707 DOI: 10.3389/fnmol.2018.00062  0.72
2017 Biswas SC, Sanphui P, Chatterjee N, Kemeny S, Greene LA. Cdc25A phosphatase: a key cell cycle protein that regulates neuron death in disease and development. Cell Death & Disease. 8: e2692. PMID 28333146 DOI: 10.1038/cddis.2017.115  0.64
2016 Chatterjee N, Sanphui P, Kemeny S, Greene LA, Biswas SC. Role and regulation of Cdc25A phosphatase in neuron death induced by NGF deprivation or β-amyloid. Cell Death Discovery. 2: 16083. PMID 28028440 DOI: 10.1038/cddiscovery.2016.83  0.64
2016 Pasini S, Liu J, Corona C, Peze-Heidsieck E, Shelanski M, Greene LA. Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα. Scientific Reports. 6: 36952. PMID 27841340 DOI: 10.1038/srep36952  0.44
2016 Karpel-Massler G, Horst BA, Shu C, Chau L, Tsujiuchi T, Bruce JN, Canoll P, Greene LA, Angelastro JM, Siegelin MD. A synthetic cell-penetrating dominant-negative ATF5 peptide exerts anti-cancer activity against a broad spectrum of treatment resistant cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27126996 DOI: 10.1158/1078-0432.CCR-15-2827  0.48
2016 Cates CC, Arias AD, Nakayama Wong LS, Lamé MW, Sidorov M, Cayanan G, Rowland DJ, Fung J, Karpel-Massler G, Siegelin MD, Greene LA, Angelastro JM. Regression/Eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide. Oncotarget. PMID 26863637 DOI: 10.18632/oncotarget.7212  0.48
2015 Aimé P, Sun X, Zareen N, Rao A, Berman Z, Volpicelli-Daley L, Bernd P, Crary JF, Levy OA, Greene LA. Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 10731-49. PMID 26224857 DOI: 10.1523/JNEUROSCI.0614-15.2015  1
2015 Pasini S, Corona C, Liu J, Greene LA, Shelanski ML. Specific downregulation of hippocampal ATF4 reveals a necessary role in synaptic plasticity and memory. Cell Reports. 11: 183-91. PMID 25865882 DOI: 10.1016/j.celrep.2015.03.025  1
2014 Grace PM, Ramos KM, Rodgers KM, Wang X, Hutchinson MR, Lewis MT, Morgan KN, Kroll JL, Taylor FR, Strand KA, Zhang Y, Berkelhammer D, Huey MG, Greene LI, Cochran TA, et al. Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae. Neuroscience. 280: 299-317. PMID 25241065 DOI: 10.1016/j.neuroscience.2014.09.020  0.64
2014 Romaní-Aumedes J, Canal M, Martín-Flores N, Sun X, Pérez-Fernández V, Wewering S, Fernández-Santiago R, Ezquerra M, Pont-Sunyer C, Lafuente A, Alberch J, Luebbert H, Tolosa E, Levy OA, Greene LA, et al. Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease. Cell Death & Disease. 5: e1364. PMID 25101677 DOI: 10.1038/cddis.2014.333  1
2014 Liu J, Pasini S, Shelanski ML, Greene LA. Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology. Frontiers in Cellular Neuroscience. 8: 177. PMID 25071442 DOI: 10.3389/fncel.2014.00177  1
2013 Zareen N, Biswas SC, Greene LA. A feed-forward loop involving Trib3, Akt and FoxO mediates death of NGF-deprived neurons. Cell Death and Differentiation. 20: 1719-30. PMID 24212932 DOI: 10.1038/cdd.2013.128  1
2013 Jean YY, Ribe EM, Pero ME, Moskalenko M, Iqbal Z, Marks LJ, Greene LA, Troy CM. Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death. The Biochemical Journal. 455: 15-25. PMID 23815625 DOI: 10.1042/BJ20130556  1
2013 Sun X, Liu J, Crary JF, Malagelada C, Sulzer D, Greene LA, Levy OA. ATF4 protects against neuronal death in cellular Parkinson's disease models by maintaining levels of parkin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2398-407. PMID 23392669 DOI: 10.1523/JNEUROSCI.2292-12.2013  1
2012 Grau CM, Greene LA. Use of PC12 cells and rat superior cervical ganglion sympathetic neurons as models for neuroprotective assays relevant to Parkinson's disease. Methods in Molecular Biology (Clifton, N.J.). 846: 201-11. PMID 22367813 DOI: 10.1007/978-1-61779-536-7_18  1
2012 Chalazonitis A, Gershon MD, Greene LA. Cell death and the developing enteric nervous system. Neurochemistry International. 61: 839-47. PMID 22342822 DOI: 10.1016/j.neuint.2012.01.028  1
2012 Wilhelm M, Kukekov NV, Schmit TL, Biagas KV, Sproul AA, Gire S, Maes ME, Xu Z, Greene LA. Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. The Journal of Biological Chemistry. 287: 2247-56. PMID 22128169 DOI: 10.1074/jbc.M111.269431  1
2012 Lee HY, Angelastro JM, Kenney AM, Mason CA, Greene LA. Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells. Developmental Neurobiology. 72: 789-804. PMID 22095825 DOI: 10.1002/dneu.20979  1
2012 Arias A, Lamé MW, Santarelli L, Hen R, Greene LA, Angelastro JM. Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas. Oncogene. 31: 739-51. PMID 21725368 DOI: 10.1038/onc.2011.276  1
2011 Greene LA, Levy O, Malagelada C. Akt as a victim, villain and potential hero in Parkinson's disease pathophysiology and treatment. Cellular and Molecular Neurobiology. 31: 969-78. PMID 21547489 DOI: 10.1007/s10571-011-9671-8  1
2011 Willett RT, Greene LA. Gata2 is required for migration and differentiation of retinorecipient neurons in the superior colliculus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4444-55. PMID 21430145 DOI: 10.1523/JNEUROSCI.4616-10.2011  1
2011 Malagelada C, López-Toledano MA, Willett RT, Jin ZH, Shelanski ML, Greene LA. RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3186-96. PMID 21368030 DOI: 10.1523/JNEUROSCI.4011-10.2011  1
2010 Biswas SC, Zhang Y, Iyirhiaro G, Willett RT, Rodriguez Gonzalez Y, Cregan SP, Slack RS, Park DS, Greene LA. Sertad1 plays an essential role in developmental and pathological neuron death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3973-82. PMID 20237268 DOI: 10.1523/JNEUROSCI.6421-09.2010  1
2010 Malagelada C, Jin ZH, Jackson-Lewis V, Przedborski S, Greene LA. Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1166-75. PMID 20089925 DOI: 10.1523/JNEUROSCI.3944-09.2010  1
2009 Sproul AA, Xu Z, Wilhelm M, Gire S, Greene LA. Cbl negatively regulates JNK activation and cell death. Cell Research. 19: 950-61. PMID 19546888 DOI: 10.1038/cr.2009.74  1
2009 Li G, Li W, Angelastro JM, Greene LA, Liu DX. Identification of a novel DNA binding site and a transcriptional target for activating transcription factor 5 in c6 glioma and mcf-7 breast cancer cells. Molecular Cancer Research : McR. 7: 933-43. PMID 19531563 DOI: 10.1158/1541-7786.MCR-08-0365  1
2009 Zareen N, Greene LA. Protocol for culturing sympathetic neurons from rat superior cervical ganglia (SCG). Journal of Visualized Experiments : Jove. PMID 19229183 DOI: 10.3791/988  1
2009 Lee HY, Greene LA, Mason CA, Manzini MC. Isolation and culture of post-natal mouse cerebellar granule neuron progenitor cells and neurons. Journal of Visualized Experiments : Jove. PMID 19229177 DOI: 10.3791/990  1
2009 Levy OA, Malagelada C, Greene LA. Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps. Apoptosis : An International Journal On Programmed Cell Death. 14: 478-500. PMID 19165601 DOI: 10.1007/s10495-008-0309-3  1
2009 Greene LA, Lee HY, Angelastro JM. The transcription factor ATF5: role in neurodevelopment and neural tumors. Journal of Neurochemistry. 108: 11-22. PMID 19046351 DOI: 10.1111/j.1471-4159.2008.05749.x  1
2008 Malagelada C, Jin ZH, Greene LA. RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14363-71. PMID 19118169 DOI: 10.1523/JNEUROSCI.3928-08.2008  1
2008 Biswas SC, Buteau J, Greene LA. Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction. Neurochemical Research. 33: 1845-51. PMID 18351462 DOI: 10.1007/s11064-008-9646-4  1
2008 Malagelada C, Greene LA. PC12 Cells as a model for parkinson's disease research Parkinson's Disease. 375-387. DOI: 10.1016/B978-0-12-374028-1.00029-4  1
2007 Wilhelm M, Kukekov NV, Xu Z, Greene LA. Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH. Developmental Neuroscience. 29: 355-62. PMID 17762203 DOI: 10.1159/000105476  1
2007 Biswas SC, Shi Y, Sproul A, Greene LA. Pro-apoptotic Bim induction in response to nerve growth factor deprivation requires simultaneous activation of three different death signaling pathways. The Journal of Biological Chemistry. 282: 29368-74. PMID 17702754 DOI: 10.1074/jbc.M702634200  1
2007 Monaco SE, Angelastro JM, Szabolcs M, Greene LA. The transcription factor ATF5 is widely expressed in carcinomas, and interference with its function selectively kills neoplastic, but not nontransformed, breast cell lines. International Journal of Cancer. Journal International Du Cancer. 120: 1883-90. PMID 17266024 DOI: 10.1002/ijc.22469  1
2007 Biswas SC, Shi Y, Vonsattel JP, Leung CL, Troy CM, Greene LA. Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 893-900. PMID 17251431 DOI: 10.1523/JNEUROSCI.3524-06.2007  1
2007 Greene LA, Liu DX, Troy CM, Biswas SC. Cell cycle molecules define a pathway required for neuron death in development and disease. Biochimica Et Biophysica Acta. 1772: 392-401. PMID 17229557 DOI: 10.1016/j.bbadis.2006.12.003  1
2007 Wilhelm M, Xu Z, Kukekov NV, Gire S, Greene LA. Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. The Journal of Biological Chemistry. 282: 1288-95. PMID 17095503 DOI: 10.1074/jbc.M607038200  1
2006 Malagelada C, Ryu EJ, Biswas SC, Jackson-Lewis V, Greene LA. RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9996-10005. PMID 17005863 DOI: 10.1523/JNEUROSCI.3292-06.2006  1
2006 Kukekov NV, Xu Z, Greene LA. Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs. The Journal of Biological Chemistry. 281: 15517-24. PMID 16571722 DOI: 10.1074/jbc.M601056200  1
2006 Xu Z, Greene LA. Activation of the apoptotic JNK pathway through the Rac1-binding scaffold protein POSH. Methods in Enzymology. 406: 479-89. PMID 16472680 DOI: 10.1016/S0076-6879(06)06036-8  1
2006 Xu Z, Sproul A, Wang W, Kukekov N, Greene LA. Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis. The Journal of Biological Chemistry. 281: 303-12. PMID 16230351 DOI: 10.1074/jbc.M509060200  1
2006 Angelastro JM, Canoll PD, Kuo J, Weicker M, Costa A, Bruce JN, Greene LA. Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5. Oncogene. 25: 907-16. PMID 16170340 DOI: 10.1038/sj.onc.1209116  1
2006 Wang Q, Maniati M, Jabado O, Pavlaki M, Troy CM, Greene LA, Stefanis L. RAIDD is required for apoptosis of PC12 cells and sympathetic neurons induced by trophic factor withdrawal. Cell Death and Differentiation. 13: 75-83. PMID 15947787 DOI: 10.1038/sj.cdd.4401690  1
2006 Teng KK, Angelastro JM, Cunningham ME, Greene LA. Cultured PC12 cells: A model for neuronal function, differentiation, and survival Cell Biology, Four-Volume Set. 1: 171-176. DOI: 10.1016/B978-012164730-8/50022-8  1
2005 Greene LA, Angelastro JM. You can't go home again: transcriptionally driven alteration of cell signaling by NGF. Neurochemical Research. 30: 1347-52. PMID 16341597 DOI: 10.1007/s11064-005-8807-y  1
2005 Xu Z, Kukekov NV, Greene LA. Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop. Molecular and Cellular Biology. 25: 9949-59. PMID 16260609 DOI: 10.1128/MCB.25.22.9949-9959.2005  1
2005 Biswas SC, Ryu E, Park C, Malagelada C, Greene LA. Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease. Neurochemical Research. 30: 839-45. PMID 16187218 DOI: 10.1007/s11064-005-6877-5  1
2005 Biswas SC, Liu DX, Greene LA. Bim is a direct target of a neuronal E2F-dependent apoptotic pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8349-58. PMID 16162916 DOI: 10.1523/JNEUROSCI.1570-05.2005  1
2005 Silva RM, Ries V, Oo TF, Yarygina O, Jackson-Lewis V, Ryu EJ, Lu PD, Marciniak SJ, Ron D, Przedborski S, Kholodilov N, Greene LA, Burke RE. CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. Journal of Neurochemistry. 95: 974-86. PMID 16135078 DOI: 10.1111/j.1471-4159.2005.03428.x  1
2005 Mason JL, Angelastro JM, Ignatova TN, Kukekov VG, Lin G, Greene LA, Goldman JE. ATF5 regulates the proliferation and differentiation of oligodendrocytes. Molecular and Cellular Neurosciences. 29: 372-80. PMID 15950153 DOI: 10.1016/j.mcn.2005.03.004  1
2005 Angelastro JM, Mason JL, Ignatova TN, Kukekov VG, Stengren GB, Goldman JE, Greene LA. Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3889-99. PMID 15829641 DOI: 10.1523/JNEUROSCI.3447-04.2005  1
2005 Liu DX, Nath N, Chellappan SP, Greene LA. Regulation of neuron survival and death by p130 and associated chromatin modifiers. Genes & Development. 19: 719-32. PMID 15769944 DOI: 10.1101/gad.1296405  1
2005 Ryu EJ, Angelastro JM, Greene LA. Analysis of gene expression changes in a cellular model of Parkinson disease. Neurobiology of Disease. 18: 54-74. PMID 15649696 DOI: 10.1016/j.nbd.2004.08.016  1
2004 Davidson TJ, Harel S, Arboleda VA, Prunell GF, Shelanski ML, Greene LA, Troy CM. Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10040-6. PMID 15537872 DOI: 10.1523/JNEUROSCI.3643-04.2004  1
2004 Liu DX, Biswas SC, Greene LA. B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8720-5. PMID 15470138 DOI: 10.1523/JNEUROSCI.1821-04.2004  1
2004 Eisenhofer G, Bornstein SR, Brouwers FM, Cheung NK, Dahia PL, de Krijger RR, Giordano TJ, Greene LA, Goldstein DS, Lehnert H, Manger WM, Maris JM, Neumann HP, Pacak K, Shulkin BL, et al. Malignant pheochromocytoma: current status and initiatives for future progress. Endocrine-Related Cancer. 11: 423-36. PMID 15369446 DOI: 10.1677/erc.1.00829  1
2004 Greene LA, Biswas SC, Liu DX. Cell cycle molecules and vertebrate neuron death: E2F at the hub. Cell Death and Differentiation. 11: 49-60. PMID 14647236 DOI: 10.1038/sj.cdd.4401341  1
2003 Greene LE, Law M, Goldberger J, Kim F, Johnson JC, Zhang Y, Saykally RJ, Yang P. Low-temperature wafer-scale production of ZnO nanowire arrays. Angewandte Chemie (International Ed. in English). 42: 3031-4. PMID 12851963 DOI: 10.1002/anie.200351461  0.64
2003 Angelastro JM, Ignatova TN, Kukekov VG, Steindler DA, Stengren GB, Mendelsohn C, Greene LA. Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4590-600. PMID 12805299 DOI: 10.1523/JNEUROSCI.23-11-04590.2003  1
2003 Xu Z, Kukekov NV, Greene LA. POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. The Embo Journal. 22: 252-61. PMID 12514131 DOI: 10.1093/emboj/cdg021  1
2002 Ryu EJ, Harding HP, Angelastro JM, Vitolo OV, Ron D, Greene LA. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10690-8. PMID 12486162  1
2002 Töröcsik B, Angelastro JM, Greene LA. The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8971-80. PMID 12388604  1
2002 Biswas SC, Greene LA. Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation. The Journal of Biological Chemistry. 277: 49511-6. PMID 12388545 DOI: 10.1074/jbc.M208086200  1
2002 Angelastro JM, Töröcsik B, Greene LA. Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins. Bmc Neuroscience. 3: 3. PMID 11922865 DOI: 10.1186/1471-2202-3-3  1
2002 Angelastro JM, Ryu EJ, Törõcsik B, Fiske BK, Greene LA. Blue-white selection step enhances the yield of SAGE concatemers. Biotechniques. 32: 484, 486. PMID 11911650  1
2001 Stefanis L, Larsen KE, Rideout HJ, Sulzer D, Greene LA. Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9549-60. PMID 11739566  1
2001 Liu DX, Greene LA. Regulation of neuronal survival and death by E2F-dependent gene repression and derepression Neuron. 32: 425-438. PMID 11709154 DOI: 10.1016/S0896-6273(01)00495-0  1
2001 Liu DX, Greene LA. Neuronal apoptosis at the G1/S cell cycle checkpoint Cell and Tissue Research. 305: 217-228. PMID 11545259 DOI: 10.1007/s004410100396  1
2001 Troy CM, Rabacchi SA, Hohl JB, Angelastro JM, Greene LA, Shelanski ML. Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5007-16. PMID 11438576  1
2001 Xu Z, Maroney AC, Dobrzanski P, Kukekov NV, Greene LA. The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis. Molecular and Cellular Biology. 21: 4713-24. PMID 11416147 DOI: 10.1128/MCB.21.14.4713-4724.2001  1
2001 Valavanis C, Hu Y, Yang Y, Osborne BA, Chouaib S, Greene L, Ashwell JD, Schwartz LM. Model cell lines for the study of apoptosis in vitro. Methods in Cell Biology. 66: 417-36. PMID 11396014 DOI: 10.1016/S0091-679X(01)66019-9  1
2001 Maroney AC, Finn JP, Connors TJ, Durkin JT, Angeles T, Gessner G, Xu Z, Meyer SL, Savage MJ, Greene LA, Scott RW, Vaught JL. Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family. The Journal of Biological Chemistry. 276: 25302-8. PMID 11325962 DOI: 10.1074/jbc.M011601200  1
2001 Troy CM, Rabacchi SA, Xu Z, Maroney AC, Connors TJ, Shelanski ML, Greene LA. beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation. Journal of Neurochemistry. 77: 157-64. PMID 11279271 DOI: 10.1046/j.1471-4159.2001.00218.x  1
2001 Angelastro JM, Moon NY, Liu DX, Yang AS, Greene LA, Franke TF. Characterization of a novel isoform of caspase-9 that inhibits apoptosis. The Journal of Biological Chemistry. 276: 12190-200. PMID 11278518 DOI: 10.1074/jbc.M009523200  1
2001 Stefanis L, Kholodilov N, Rideout HJ, Burke RE, Greene LA. Synuclein-1 is selectively up-regulated in response to nerve growth factor treatment in PC12 cells. Journal of Neurochemistry. 76: 1165-76. PMID 11181836 DOI: 10.1046/j.1471-4159.2001.00114.x  1
2001 Cunningham ME, Kitajewski JK, Greene LA. Efficient generation of stable pheochromocytoma (PC12) cell lines using a recombinant retrovirus (LNC). Methods in Molecular Biology (Clifton, N.J.). 169: 135-47. PMID 11142008  1
2000 Park DS, Obeidat A, Giovanni A, Greene LA. Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment. Neurobiology of Aging. 21: 771-81. PMID 11124421 DOI: 10.1016/S0197-4580(00)00220-7  1
2000 Sulzer D, Bogulavsky J, Larsen KE, Behr G, Karatekin E, Kleinman MH, Turro N, Krantz D, Edwards RH, Greene LA, Zecca L. Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles. Proceedings of the National Academy of Sciences of the United States of America. 97: 11869-74. PMID 11050221 DOI: 10.1073/pnas.97.22.11869  1
2000 Angelastro JM, Klimaschewski L, Tang S, Vitolo OV, Weissman TA, Donlin LT, Shelanski ML, Greene LA. Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling. Proceedings of the National Academy of Sciences of the United States of America. 97: 10424-9. PMID 10984536 DOI: 10.1073/PNAS.97.19.10424  1
2000 Park DS, Morris EJ, Bremner R, Keramaris E, Padmanabhan J, Rosenbaum M, Shelanski ML, Geller HM, Greene LA. Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3104-14. PMID 10777774  1
2000 Mukai J, Hachiya T, Shoji-Hoshino S, Kimura MT, Nadano D, Suvanto P, Hanaoka T, Li Y, Irie S, Greene LA, Sato TA. NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR Journal of Biological Chemistry. 275: 17566-17570. PMID 10764727 DOI: 10.1074/jbc.C000140200  1
1999 Friedman WJ, Greene LA. Neurotrophin signaling via Trks and p75 Experimental Cell Research. 253: 131-142. PMID 10579918 DOI: 10.1006/excr.1999.4705  1
1999 Itagaki C, Isobe T, Taoka M, Natsume T, Nomura N, Horigome T, Omata S, Ichinose H, Nagatsu T, Greene LA, Ichimura T. Stimulus-coupled interaction of tyrosine hydroxylase with 14-3-3 proteins Biochemistry. 38: 15673-15680. PMID 10569954 DOI: 10.1021/bi9914255  1
1999 Maroney AC, Finn JP, Bozyczko-Coyne D, O'Kane TM, Neff NT, Tolkovsky AM, Park DS, Yan CY, Troy CM, Greene LA. CEP-1347 (KT7515), an inhibitor of JNK activation, rescues sympathetic neurons and neuronally differentiated PC12 cells from death evoked by three distinct insults. Journal of Neurochemistry. 73: 1901-12. PMID 10537048  1
1999 Padmanabhan J, Park DS, Greene LA, Shelanski ML. Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8747-56. PMID 10516294  1
1999 Stefanis L, Park DS, Friedman WJ, Greene LA. Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6235-47. PMID 10414953  1
1998 Cunningham ME, Greene LA. A function-structure model for NGF-activated TRK. The Embo Journal. 17: 7282-93. PMID 9857185 DOI: 10.1093/emboj/17.24.7282  1
1998 Park DS, Morris EJ, Padmanabhan J, Shelanski ML, Geller HM, Greene LA. Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents. The Journal of Cell Biology. 143: 457-67. PMID 9786955 DOI: 10.1083/jcb.143.2.457  1
1998 Ferrari G, Greene LA. Promotion of neuronal survival by GM1 ganglioside. Phenomenology and mechanism of action Annals of the New York Academy of Sciences. 845: 263-273. PMID 9668360 DOI: 10.1111/j.1749-6632.1998.tb09679.x  1
1998 Farinelli SE, Greene LA, Friedman WJ. Neuroprotective actions of dipyridamole on cultured CNS neurons Journal of Neuroscience. 18: 5112-5123. PMID 9651195  1
1998 Anderson BL, Boldogh I, Evangelista M, Boone C, Greene LA, Pon LA. The Src homology domain 3 (SH3) of a yeast type I myosin, Myo5p, binds to verprolin and is required for targeting to sites of actin polarization. The Journal of Cell Biology. 141: 1357-70. PMID 9628892 DOI: 10.1083/jcb.141.6.1357  1
1998 Van Irene CY, Greene LA. Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway Journal of Neuroscience. 18: 4042-4049. PMID 9592085  1
1998 Angelastro JM, Ho CL, Frappier T, Liem RK, Greene LA. Peripherin is tyrosine-phosphorylated at its carboxyl-terminal tyrosine. Journal of Neurochemistry. 70: 540-9. PMID 9453548  1
1998 Park DS, Morris EJ, Stefanis L, Troy CM, Shelanski ML, Geller HM, Greene LA. Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 830-40. PMID 9437005  1
1997 Park DS, Stefanis L, Greene LA. Ordering the multiple pathways of apoptosis. Trends in Cardiovascular Medicine. 7: 294-301. PMID 21235899 DOI: 10.1016/S1050-1738(97)00090-X  1
1997 Park DS, Levine B, Ferrari G, Greene LA. Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8975-83. PMID 9364045  1
1997 Stefanis L, Troy CM, Qi H, Greene LA. Inhibitors of trypsin-like serine proteases inhibit processing of the caspase Nedd-2 and protect PC12 cells and sympathetic neurons from death evoked by withdrawal of trophic support. Journal of Neurochemistry. 69: 1425-37. PMID 9326271  1
1997 Stefanis L, Burke RE, Greene LA. Apoptosis in neurodegenerative disorders. Current Opinion in Neurology. 10: 299-305. PMID 9266153  1
1997 Cunningham ME, Stephens RM, Kaplan DR, Greene LA. Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor. The Journal of Biological Chemistry. 272: 10957-67. PMID 9099755 DOI: 10.1074/jbc.272.16.10957  1
1997 Troy CM, Stefanis L, Greene LA, Shelanski ML. Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1911-8. PMID 9045720  1
1997 Park DS, Morris EJ, Greene LA, Geller HM. G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1256-70. PMID 9006970  1
1997 Troy CM, Stefanis L, Greene LA, Shelanski ML. Mechanisms of neuronal degeneration: a final common pathway? Advances in Neurology. 72: 103-11. PMID 8993689  1
1996 Stefanis L, Park DS, Yan CY, Farinelli SE, Troy CM, Shelanski ML, Greene LA. Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis. The Journal of Biological Chemistry. 271: 30663-71. PMID 8940042 DOI: 10.1074/jbc.271.48.30663  1
1996 Park DS, Stefanis L, Yan CY, Farinelli SE, Greene LA. Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells. The Journal of Biological Chemistry. 271: 21898-905. PMID 8702992 DOI: 10.1074/jbc.271.36.21898  1
1996 Park DS, Farinelli SE, Greene LA. Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons. The Journal of Biological Chemistry. 271: 8161-9. PMID 8626506 DOI: 10.1074/jbc.271.14.8161  1
1996 Farinelli SE, Park DS, Greene LA. Nitric oxide delays the death of trophic factor-deprived PC12 cells and sympathetic neurons by a cGMP-mediated mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2325-34. PMID 8601812  1
1987 Greene LA, Aletta JM, Rukenstein A, Green SH. PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation. Methods in Enzymology. 147: 207-16. PMID 3670084  1
1986 Black MM, Aletta JM, Greene LA. Regulation of microtubule composition and stability during nerve growth factor-promoted neurite outgrowth. The Journal of Cell Biology. 103: 545-57. PMID 3733878  0.32
1986 Greene LA, Drexler SA, Connolly JL, Rukenstein A, Green SH. Selective inhibition of responses to nerve growth factor and of microtubule-associated protein phosphorylation by activators of adenylate cyclase. The Journal of Cell Biology. 103: 1967-78. PMID 3023392 DOI: 10.1083/jcb.103.5.1967  1
1986 Green SH, Greene LA. A single Mr approximately 103,000 125I-beta-nerve growth factor-affinity-labeled species represents both the low and high affinity forms of the nerve growth factor receptor. The Journal of Biological Chemistry. 261: 15316-26. PMID 3021771  1
1986 Green SH, Rydel RE, Connolly JL, Greene LA. PC12 cell mutants that possess low- but not high-affinity nerve growth factor receptors neither respond to nor internalize nerve growth factor. The Journal of Cell Biology. 102: 830-43. PMID 3005338  1
1983 Greene LA, Bernd P, Black MM, Burstein DE, Connolly JL, Rukenstein A, Seeley PJ. Genomic and non-genomic actions of nerve growth factor in development. Progress in Brain Research. 58: 347-57. PMID 6314431 DOI: 10.1016/S0079-6123(08)60036-9  1
1982 Black MM, Greene LA. Changes in the colchicine susceptibility of microtubules associated with neurite outgrowth: studies with nerve growth factor-responsive PC12 pheochromocytoma cells. The Journal of Cell Biology. 95: 379-86. PMID 7142295  1
1982 Kouvelas ED, Greene LA. Development of muscarinic cholinergic receptors in chick embryo sympathetic ganglia. Developmental Neuroscience. 5: 375-8. PMID 7140584  1
1982 Greene LA, Burstein DE, Black MM. The role of transcription-dependent priming in nerve growth factor promoted neurite outgrowth. Developmental Biology. 91: 305-16. PMID 7095268 DOI: 10.1016/0012-1606(82)90037-9  1
1979 Kouvelas ED, Luckenbill-Edds L, LaVail JH, Greene LA. Effects of eye removal on receptors of alpha-bungarotoxin in the optic lobes of chick brain. Neuroscience Letters. 11: 99-102. PMID 431891 DOI: 10.1016/0304-3940(79)90063-6  1
1978 Kouvelas ED, Dichter MA, Greene LA. Chick sympathetic neurons develop receptors for alpha-bungarotoxin in vitro, but the toxin does not block nicotinic receptors. Brain Research. 154: 83-93. PMID 698824 DOI: 10.1016/0006-8993(78)91053-3  1
1976 Kouvelas ED, Greene LA. The binding properties and regional ontogeny of receptors for alpha-bungarotoxin in chick brain. Brain Research. 113: 111-26. PMID 953721 DOI: 10.1016/0006-8993(76)90010-X  1
1975 Greene LA, Shain W, Chalazonitis A, Breakfield X, Minna J, Coon HG, Nirenberg M. Neuronal properties of hybrid neuroblastoma X sympathetic ganglion cells. Proceedings of the National Academy of Sciences of the United States of America. 72: 4923-7. PMID 1745 DOI: 10.1073/pnas.72.12.4923  1
1974 Chalazonitis A, Greene LA, Nirenberg M. Electrophysiological chracteristics of chick embryo sympathetic neurons in dissociated cell culture. Brain Research. 68: 235-52. PMID 4826897 DOI: 10.1016/0006-8993(74)90393-X  1
1973 Greene LA, Sytkowski AJ, Vogel Z, Nirenberg MW. -Bungarotoxin used as a probe for acetylcholine receptors of cultured neurones. Nature. 243: 163-6. PMID 4550035 DOI: 10.1038/243163a0  1
1971 Greene LA, Tomita JT, Varon S. Growth-stimulating activities of mouse submaxillary esteropeptidases on chick embryo fibroblasts in vitro. Experimental Cell Research. 64: 387-95. PMID 5100758 DOI: 10.1016/0014-4827(71)90092-9  1
1969 Greene LA, Shooter EM, Varon S. Subunit interaction and enzymatic activity of mouse 7S nerve growth factor. Biochemistry. 8: 3735-41. PMID 5820664  1
1969 Smith AP, Greene LA, Fish HR, Varon S, Shooter EM. Subunit equilibria of the 7S nerve growth factor protein. Biochemistry. 8: 4918-26. PMID 5365786 DOI: 10.1021/bi00840a040  1
1968 Greene LA, Shooter EM, Varon S. Enzymatic activities of mouse nerve growth factor and its subunits. Proceedings of the National Academy of Sciences of the United States of America. 60: 1383-8. PMID 5244746  1
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