Hongbo Chi - Publications

Affiliations: 
Immunology St Jude Children's Research Hospital/UTHSC 

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Year Citation  Score
2023 Norton EG, Chapman NM, Chi H. Strengthening bonds via RyR2 inhibition helps immune suppression. The Journal of Clinical Investigation. 133. PMID 38099491 DOI: 10.1172/JCI172986  0.421
2023 Zhou P, Chi H. Fructose sweetens the adipocyte-T cell alliance against tumors. Cell Metabolism. 35: 2093-2094. PMID 38056424 DOI: 10.1016/j.cmet.2023.11.004  0.434
2023 Guo C, Chi H. Immunometabolism of dendritic cells in health and disease. Advances in Immunology. 160: 83-116. PMID 38042587 DOI: 10.1016/bs.ai.2023.10.002  0.332
2023 Bell M, Lange S, Sejdiu BI, Ibanez J, Shi H, Sun X, Meng X, Nguyen P, Sutton M, Wagner J, Kc A, Langfitt D, Patil SL, Tan H, Pandey RV, ... ... Chi H, et al. Modular chimeric cytokine receptors with leucine zippers enhance the antitumour activity of CAR T cells via JAK/STAT signalling. Nature Biomedical Engineering. PMID 38036617 DOI: 10.1038/s41551-023-01143-w  0.464
2023 Fan H, Xia S, Xiang J, Li Y, Ross MO, Lim SA, Yang F, Tu J, Xie L, Dougherty U, Zhang FQ, Zheng Z, Zhang R, Wu R, Dong L, ... ... Chi H, et al. Trans-vaccenic acid reprograms CD8 T cells and anti-tumour immunity. Nature. PMID 37993715 DOI: 10.1038/s41586-023-06749-3  0.342
2023 Zhou P, Shi H, Huang H, Sun X, Yuan S, Chapman NM, Connelly JP, Lim SA, Saravia J, Kc A, Pruett-Miller SM, Chi H. Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer. Nature. PMID 37968405 DOI: 10.1038/s41586-023-06733-x  0.54
2023 Su W, Saravia J, Risch I, Rankin S, Guy C, Chapman NM, Shi H, Sun Y, Kc A, Li W, Huang H, Lim SA, Hu H, Wang Y, Liu D, ... ... Chi H, et al. CXCR6 orchestrates brain CD8 T cell residency and limits mouse Alzheimer's disease pathology. Nature Immunology. PMID 37679549 DOI: 10.1038/s41590-023-01604-z  0.468
2023 Reina-Campos M, Heeg M, Kennewick K, Mathews IT, Galletti G, Luna V, Nguyen Q, Huang H, Milner JJ, Hu KH, Vichaidit A, Santillano N, Boland BS, Chang JT, Jain M, ... ... Chi H, et al. Metabolic programs of T cell tissue residency empower tumour immunity. Nature. PMID 37648857 DOI: 10.1038/s41586-023-06483-w  0.504
2023 Guo C, You Z, Shi H, Sun Y, Du X, Palacios G, Guy C, Yuan S, Chapman NM, Lim SA, Sun X, Saravia J, Rankin S, Dhungana Y, Chi H. SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity. Nature. PMID 37407815 DOI: 10.1038/s41586-023-06299-8  0.501
2023 You Z, Chi H. Lipid metabolism in dendritic cell biology. Immunological Reviews. PMID 37172120 DOI: 10.1111/imr.13215  0.367
2023 Yu J, Ding L, Shi H, Qian C, Burdyshaw C, Veloso J, Khatamian A, Pan Q, Dhungana Y, Xie Z, Risch I, Yang X, Huang X, Yan L, Rusch M, ... ... Chi H, et al. scMINER: a mutual information-based framework for identifying hidden drivers from single-cell omics data. Research Square. PMID 36747874 DOI: 10.21203/rs.3.rs-2476875/v1  0.331
2023 Ding L, Shi H, Qian C, Burdyshaw C, Veloso JP, Khatamian A, Pan Q, Dhungana Y, Xie Z, Risch I, Yang X, Huang X, Yan L, Rusch M, Brewer M, ... ... Chi H, et al. scMINER: a mutual information-based framework for identifying hidden drivers from single-cell omics data. Biorxiv : the Preprint Server For Biology. PMID 36747870 DOI: 10.1101/2023.01.26.523391  0.331
2023 Yuan S, Chi H. Early immune pressure makes tumors metabolically stronger. Cell Metabolism. 35: 3-5. PMID 36599301 DOI: 10.1016/j.cmet.2022.12.009  0.312
2022 Blanco DB, Chapman NM, Raynor JL, Xu C, Su W, Kc A, Li W, Lim SA, Schattgen S, Shi H, Risch I, Sun Y, Dhungana Y, Kim Y, Wei J, ... ... Chi H, et al. PTEN directs developmental and metabolic signaling for innate-like T cell fate and tissue homeostasis. Nature Cell Biology. PMID 36302969 DOI: 10.1038/s41556-022-01011-w  0.541
2022 Guo A, Huang H, Zhu Z, Chen MJ, Shi H, Yuan S, Sharma P, Connelly JP, Liedmann S, Dhungana Y, Li Z, Haydar D, Yang M, Beere H, Yustein JT, ... ... Chi H, et al. cBAF complex components and MYC cooperate early in CD8 T cell fate. Nature. PMID 35732731 DOI: 10.1038/s41586-022-04849-0  0.496
2022 Li Y, Yang X, Sun Y, Li Z, Yang W, Ju B, Easton J, Pei D, Cheng C, Lee SH, Pui CH, Yu J, Chi H, Yang JJ. The Impact of T cell Immunity on Chemotherapy Response in Childhood Acute Lymphoblastic Leukemia. Blood. PMID 35675514 DOI: 10.1182/blood.2021014495  0.446
2022 Thangavelu G, Andrejeva G, Bolivar-Wagers S, Jin S, Zaiken MC, Loschi M, Aguilar EG, Furlan SN, Brown CC, Lee YC, Hyman CM, Feser CJ, Panoskaltsis-Mortari A, Hippen KL, MacDonald KP, ... ... Chi H, et al. Retinoic acid signaling acts as a rheostat to balance Treg function. Cellular & Molecular Immunology. PMID 35581350 DOI: 10.1038/s41423-022-00869-y  0.412
2022 Lim SA, Su W, Chapman NM, Chi H. Lipid metabolism in T cell signaling and function. Nature Chemical Biology. 18: 470-481. PMID 35484263 DOI: 10.1038/s41589-022-01017-3  0.579
2022 Chi H. Immunometabolism at the intersection of metabolic signaling, cell fate, and systems immunology. Cellular & Molecular Immunology. 19: 299-302. PMID 35190684 DOI: 10.1038/s41423-022-00840-x  0.359
2022 Chapman NM, Chi H. Metabolic adaptation of lymphocytes in immunity and disease. Immunity. 55: 14-30. PMID 35021054 DOI: 10.1016/j.immuni.2021.12.012  0.398
2021 Oh DY, Fong L, Newell EW, Turk MJ, Chi H, Chang HY, Satpathy AT, Fairfax B, Silva-Santos B, Lantz O. Toward a better understanding of T cells in cancer. Cancer Cell. 39: 1549-1552. PMID 34906313 DOI: 10.1016/j.ccell.2021.11.010  0.462
2021 Long L, Wei J, Lim SA, Raynor JL, Shi H, Connelly JP, Wang H, Guy C, Xie B, Chapman NM, Fu G, Wang Y, Huang H, Su W, Saravia J, ... ... Chi H, et al. CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity. Nature. PMID 34795452 DOI: 10.1038/s41586-021-04109-7  0.586
2021 Raynor JL, Chi H. Investigating the Dynamic Changes in iNKT Cell Metabolic Profiles During Development. Methods in Molecular Biology (Clifton, N.J.). 2388: 181-192. PMID 34524673 DOI: 10.1007/978-1-0716-1775-5_17  0.366
2021 Shi H, Chi H. Polyamine: A metabolic compass for T helper cell fate direction. Cell. 184: 4109-4112. PMID 34358466 DOI: 10.1016/j.cell.2021.07.012  0.39
2021 Fu G, Guy CS, Chapman NM, Palacios G, Wei J, Zhou P, Long L, Wang YD, Qian C, Dhungana Y, Huang H, Kc A, Shi H, Rankin S, Brown SA, ... ... Chi H, et al. Metabolic control of T cells and humoral immunity by phosphatidylethanolamine. Nature. PMID 34234346 DOI: 10.1038/s41586-021-03692-z  0.57
2021 Gocho Y, Liu J, Hu J, Yang W, Dharia NV, Zhang J, Shi H, Du G, John A, Lin TN, Hunt J, Huang X, Rowland L, Shi L, Maxwell D, ... ... Chi H, et al. Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia. Nature Cancer. 2: 284-299. PMID 34151288 DOI: 10.1038/s43018-020-00167-4  0.456
2021 Raynor JL, Chapman NM, Chi H. Metabolic Control of Memory T-Cell Generation and Stemness. Cold Spring Harbor Perspectives in Biology. PMID 33820774 DOI: 10.1101/cshperspect.a037770  0.427
2021 Zheng W, Wei J, Zebley C, Jones LL, Dhungana Y, Wang YD, Mavuluri J, Long L, Fan Y, Youngblood B, Chi H, Geiger TL. Regnase-1 suppresses TCF-1+ precursor exhausted T cell formation to limit CAR T cell responses against ALL. Blood. PMID 33690816 DOI: 10.1182/blood.2020009309  0.486
2021 Wei J, Zheng W, Chapman NM, Geiger TL, Chi H. T cell metabolism in homeostasis and cancer immunity. Current Opinion in Biotechnology. 68: 240-250. PMID 33676144 DOI: 10.1016/j.copbio.2021.02.003  0.537
2021 Huang H, Zhou P, Wei J, Long L, Shi H, Dhungana Y, Chapman NM, Fu G, Saravia J, Raynor JL, Liu S, Palacios G, Wang YD, Qian C, Yu J, ... Chi H, et al. In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8 T cell fate decisions. Cell. PMID 33636132 DOI: 10.1016/j.cell.2021.02.021  0.523
2021 Lim SA, Wei J, Nguyen TM, Shi H, Su W, Palacios G, Dhungana Y, Chapman NM, Long L, Saravia J, Vogel P, Chi H. Lipid signalling enforces functional specialization of T cells in tumours. Nature. PMID 33627871 DOI: 10.1038/s41586-021-03235-6  0.61
2021 Raynor JL, Chi H. LCK senses asparagine for T cell activation. Nature Cell Biology. 23: 7-8. PMID 33420487 DOI: 10.1038/s41556-020-00621-6  0.458
2020 Su W, Chapman NM, Wei J, Zeng H, Dhungana Y, Shi H, Saravia J, Zhou P, Long L, Rankin S, Kc A, Vogel P, Chi H. Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector T Cells. Cell Metabolism. PMID 33207246 DOI: 10.1016/j.cmet.2020.10.022  0.594
2020 Chapman NM, Gottschalk S, Chi H. Preventing Ubiquitination Improves CAR T Cell Therapy via 'CAR Merry-Go-Around'. Immunity. 53: 243-245. PMID 32814023 DOI: 10.1016/j.immuni.2020.07.023  0.516
2020 Amersfoort J, Schaftenaar FH, Douna H, van Santbrink PJ, van Puijvelde GHM, Slütter B, Foks AC, Harms A, Moreno-Gordaliza E, Wang Y, Hankemeier T, Bot I, Chi H, Kuiper J. Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells. Cardiovascular Research. PMID 32653923 DOI: 10.1093/Cvr/Cvaa208  0.44
2020 Kennedy DE, Okoreeh MK, Maienschein-Cline M, Ai J, Veselits M, McLean KC, Dhungana Y, Wang H, Peng J, Chi H, Mandal M, Clark MR. Novel specialized cell state and spatial compartments within the germinal center. Nature Immunology. PMID 32341509 DOI: 10.1038/S41590-020-0660-2  0.32
2020 Raynor JL, Liu C, Dhungana Y, Guy C, Chapman NM, Shi H, Neale G, Sesaki H, Chi H. Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions. The Journal of Experimental Medicine. 217. PMID 32289155 DOI: 10.1084/Jem.20191157  0.455
2020 Huang H, Long L, Zhou P, Chapman NM, Chi H. mTOR signaling at the crossroads of environmental signals and T-cell fate decisions. Immunological Reviews. PMID 32212344 DOI: 10.1111/imr.12845  0.529
2020 Saravia J, Raynor JL, Chapman NM, Lim SA, Chi H. Signaling networks in immunometabolism. Cell Research. PMID 32203134 DOI: 10.1038/s41422-020-0301-1  0.511
2020 Yang K, Chi H. Autophagy modulates CD4 T-cell lineage recommitment upon pathogen infection. Cellular & Molecular Immunology. PMID 32047257 DOI: 10.1038/s41423-020-0368-0  0.337
2020 Saravia J, Zeng H, Dhungana Y, Bastardo Blanco D, Nguyen TM, Chapman NM, Wang Y, Kanneganti A, Liu S, Raynor JL, Vogel P, Neale G, Carmeliet P, Chi H. Homeostasis and transitional activation of regulatory T cells require c-Myc. Science Advances. 6: eaaw6443. PMID 31911938 DOI: 10.1126/sciadv.aaw6443  0.479
2019 Shi H, Chi H. Metabolic Control of Treg Cell Stability, Plasticity, and Tissue-Specific Heterogeneity. Frontiers in Immunology. 10: 2716. PMID 31921097 DOI: 10.3389/fimmu.2019.02716  0.476
2019 Wei J, Long L, Zheng W, Dhungana Y, Lim SA, Guy C, Wang Y, Wang YD, Qian C, Xu B, Kc A, Saravia J, Huang H, Yu J, Doench JG, ... ... Chi H, et al. Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy. Nature. PMID 31827283 DOI: 10.1038/S41586-019-1821-Z  0.468
2019 Du X, Zeng H, Liu S, Guy C, Dhungana Y, Neale G, Bergo MO, Chi H. Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress. The Journal of Experimental Medicine. PMID 31722972 DOI: 10.1084/jem.20190969  0.505
2019 Shi H, Chapman NM, Wen J, Guy C, Long L, Dhungana Y, Rankin S, Pelletier S, Vogel P, Wang H, Peng J, Guan KL, Chi H. Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb. Immunity. PMID 31668641 DOI: 10.1016/J.Immuni.2019.10.001  0.458
2019 Chapman NM, Boothby MR, Chi H. Metabolic coordination of T cell quiescence and activation. Nature Reviews. Immunology. PMID 31406325 DOI: 10.1038/s41577-019-0203-y  0.57
2019 Zhou P, Chi H. AGK Unleashes CD8 T Cell Glycolysis to Combat Tumor Growth. Cell Metabolism. 30: 233-234. PMID 31390548 DOI: 10.1016/j.cmet.2019.07.008  0.431
2019 Wang Y, Du X, Wei J, Long L, Tan H, Guy C, Dhungana Y, Qian C, Neale G, Fu YX, Yu J, Peng J, Chi H. LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity. Cell Research. PMID 30911060 DOI: 10.1038/S41422-019-0157-4  0.417
2019 Saravia J, Chapman NM, Chi H. Helper T cell differentiation. Cellular & Molecular Immunology. PMID 30867582 DOI: 10.1038/s41423-019-0220-6  0.53
2018 Karmaus PWF, Chen X, Lim SA, Herrada AA, Nguyen TM, Xu B, Dhungana Y, Rankin S, Chen W, Rosencrance C, Yang K, Fan Y, Cheng Y, Easton J, Neale G, ... ... Chi H, et al. Metabolic heterogeneity underlies reciprocal fates of T17 cell stemness and plasticity. Nature. PMID 30568299 DOI: 10.1038/S41586-018-0806-7  0.543
2018 Du X, Chapman NM, Chi H. Emerging Roles of Cellular Metabolism in Regulating Dendritic Cell Subsets and Function. Frontiers in Cell and Developmental Biology. 6: 152. PMID 30483503 DOI: 10.3389/fcell.2018.00152  0.404
2018 Shi H, Liu C, Tan H, Li Y, Nguyen TM, Dhungana Y, Guy C, Vogel P, Neale G, Rankin S, Feng Y, Peng J, Tao W, Chi H. Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity. Immunity. PMID 30413360 DOI: 10.1016/J.Immuni.2018.10.010  0.414
2018 Raynor J, Chi H. Sprouty branches out to control T cell memory. Proceedings of the National Academy of Sciences of the United States of America. PMID 30181286 DOI: 10.1073/pnas.1813460115  0.303
2018 McDonald-Hyman C, Muller JT, Loschi M, Thangavelu G, Saha A, Kumari S, Reichenbach DK, Smith MJ, Zhang G, Koehn BH, Lin J, Mitchell JS, Fife BT, Panoskaltsis-Mortari A, Feser CJ, ... ... Chi H, et al. The vimentin intermediate filament network restrains regulatory T-cell suppression of graft-versus-host disease. The Journal of Clinical Investigation. PMID 30106752 DOI: 10.1172/Jci95713  0.45
2018 Newton RH, Shrestha S, Sullivan JM, Yates KB, Compeer EB, Ron-Harel N, Blazar BR, Bensinger SJ, Haining WN, Dustin ML, Campbell DJ, Chi H, Turka LA. Maintenance of CD4 T cell fitness through regulation of Foxo1. Nature Immunology. PMID 29988091 DOI: 10.1038/S41590-018-0157-4  0.525
2018 Yang K, Blanco DB, Chen X, Dash P, Neale G, Rosencrance C, Easton J, Chen W, Cheng C, Dhungana Y, Kc A, Awad W, Guo XJ, Thomas PG, Chi H. Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells. Science Immunology. 3. PMID 29980617 DOI: 10.1126/sciimmunol.aas9818  0.536
2018 Podojil JR, Chiang MY, Ifergan I, Copeland R, Liu LN, Maloveste S, Langermann S, Liebenson D, Balabanov R, Chi H, Chen L, Vignali DAA, Miller SD. B7-H4 Modulates Regulatory CD4 T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 Complex. Journal of Immunology (Baltimore, Md. : 1950). PMID 29898965 DOI: 10.4049/Jimmunol.1700811  0.368
2018 Du X, Wen J, Wang Y, Karmaus PWF, Khatamian A, Tan H, Li Y, Guy C, Nguyen TM, Dhungana Y, Neale G, Peng J, Yu J, Chi H. Hippo/Mst signalling couples metabolic state and immune function of CD8α dendritic cells. Nature. PMID 29849151 DOI: 10.1038/S41586-018-0177-0  0.529
2018 Chapman NM, Zeng H, Nguyen TM, Wang Y, Vogel P, Dhungana Y, Liu X, Neale G, Locasale JW, Chi H. mTOR coordinates transcriptional programs and mitochondrial metabolism of activated T subsets to protect tissue homeostasis. Nature Communications. 9: 2095. PMID 29844370 DOI: 10.1038/S41467-018-04392-5  0.53
2018 Chapman NM, Chi H. Hallmarks of T-cell Exit from Quiescence. Cancer Immunology Research. 6: 502-508. PMID 29716982 DOI: 10.1158/2326-6066.CIR-17-0605  0.564
2018 Malireddi RKS, Gurung P, Mavuluri J, Dasari TK, Klco JM, Chi H, Kanneganti TD. TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation. The Journal of Experimental Medicine. PMID 29500178 DOI: 10.1084/Jem.20171922  0.304
2018 Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, Dhungana Y, Guy C, Neale G, Cloer C, Peng J, Wang D, Chi H. Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis. Science Advances. 4: eaar5701. PMID 29399633 DOI: 10.1126/Sciadv.Aar5701  0.46
2018 Yang K, Chi H. Investigating Cellular Quiescence of T Lymphocytes and Antigen-Induced Exit from Quiescence. Methods in Molecular Biology (Clifton, N.J.). 1686: 161-172. PMID 29030820 DOI: 10.1007/978-1-4939-7371-2_12  0.527
2017 Yu M, Chen Y, Zeng H, Zheng Y, Fu G, Zhu W, Broeckel U, Aggarwal P, Turner A, Neale G, Guy C, Zhu N, Chi H, Wen R, Wang D. PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development. Nature Communications. 8: 1457. PMID 29133930 DOI: 10.1038/S41467-017-01388-5  0.374
2017 Chapman NM, Shrestha S, Chi H. Metabolism in Immune Cell Differentiation and Function. Advances in Experimental Medicine and Biology. 1011: 1-85. PMID 28875486 DOI: 10.1007/978-94-024-1170-6_1  0.358
2017 Yang K, Blanco DB, Neale G, Vogel P, Avila J, Clish CB, Wu C, Shrestha S, Rankin S, Long L, Kc A, Chi H. Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling. Nature. PMID 28847007 DOI: 10.1038/nature23665  0.508
2017 Zeng H, Chi H. mTOR signaling in the differentiation and function of regulatory and effector T cells. Current Opinion in Immunology. 46: 103-111. PMID 28535458 DOI: 10.1016/j.coi.2017.04.005  0.566
2017 Wei J, Raynor J, Nguyen TM, Chi H. Nutrient and Metabolic Sensing in T Cell Responses. Frontiers in Immunology. 8: 247. PMID 28337199 DOI: 10.3389/fimmu.2017.00247  0.543
2017 Tan H, Yang K, Li Y, Shaw TI, Wang Y, Blanco DB, Wang X, Cho JH, Wang H, Rankin S, Guy C, Peng J, Chi H. Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation. Immunity. PMID 28285833 DOI: 10.1016/J.Immuni.2017.02.010  0.478
2017 Chapman NM, Chi H. Dietary Fat Inflames CD4(+) T Cell Memory in Obesity. Cell Metabolism. 25: 490-492. PMID 28273470 DOI: 10.1016/j.cmet.2017.02.012  0.445
2016 Shi LZ, Saravia J, Zeng H, Kalupahana NS, Guy CS, Neale G, Chi H. Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 27994150 DOI: 10.1073/pnas.1617669114  0.391
2016 Zeng H, Cohen S, Guy C, Shrestha S, Neale G, Brown SA, Cloer C, Kishton RJ, Gao X, Youngblood B, Do M, Li MO, Locasale JW, Rathmell JC, Chi H. mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation. Immunity. PMID 27637146 DOI: 10.1016/J.Immuni.2016.08.017  0.552
2016 Cao G, Wang Q, Li G, Meng Z, Liu H, Tong J, Huang W, Liu Z, Jia Y, Wei J, Chi H, Yang H, Zhao L, Wu Z, Hao J, et al. mTOR inhibition potentiates cytotoxicity of Vγ4 γδ T cells via up-regulating NKG2D and TNF-α. Journal of Leukocyte Biology. PMID 27256566 DOI: 10.1189/jlb.5A0116-053RR  0.539
2016 Nguyen HD, Chatterjee S, Haarberg KM, Wu Y, Bastian D, Heinrichs J, Fu J, Daenthanasanmak A, Schutt S, Shrestha S, Liu C, Wang H, Chi H, Mehrotra S, Yu XZ. Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation. The Journal of Clinical Investigation. PMID 26950421 DOI: 10.1172/JCI82587  0.447
2016 Wei J, Long L, Yang K, Guy C, Shrestha S, Chen Z, Wu C, Vogel P, Neale G, Green DR, Chi H. Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis. Nature Immunology. PMID 26808230 DOI: 10.1038/Ni.3365  0.509
2015 Li J, Du X, Shi H, Deng K, Chi H, Tao W. Mammalian sterile 20-like kinase 1 (Mst1) enhances the stability of forkhead box P3 (Foxp3) and the Function of Regulatory T cells by Modulating Foxp3 Acetylation. The Journal of Biological Chemistry. PMID 26538561 DOI: 10.1074/jbc.M115.668442  0.34
2015 Lukens JR, Gurung P, Shaw PJ, Barr MJ, Zaki MH, Brown SA, Vogel P, Chi H, Kanneganti TD. The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells. Immunity. 42: 654-64. PMID 25888258 DOI: 10.1016/J.Immuni.2015.03.006  0.485
2015 Huang G, Wang Y, Vogel P, Chi H. Control of IL-17 receptor signaling and tissue inflammation by the p38α-MKP-1 signaling axis in a mouse model of multiple sclerosis. Science Signaling. 8: ra24. PMID 25737586 DOI: 10.1126/scisignal.aaa2147  0.441
2015 Liu C, Chapman NM, Karmaus PW, Zeng H, Chi H. mTOR and metabolic regulation of conventional and regulatory T cells. Journal of Leukocyte Biology. PMID 25714803 DOI: 10.1189/Jlb.2Ri0814-408R  0.569
2015 Yang K, Chi H. AMPK helps T cells survive nutrient starvation. Immunity. 42: 4-6. PMID 25607450 DOI: 10.1016/j.immuni.2014.12.029  0.5
2015 Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nature Immunology. 16: 178-87. PMID 25559258 DOI: 10.1038/ni.3076  0.493
2015 Zeng H, Chi H. Metabolic control of regulatory T cell development and function. Trends in Immunology. 36: 3-12. PMID 25248463 DOI: 10.1016/j.it.2014.08.003  0.418
2014 Zeng H, Chi H. mTOR signaling and transcriptional regulation in T lymphocytes. Transcription. 5: e28263. PMID 25764218 DOI: 10.4161/trns.28263  0.525
2014 Yang K, Chi H. Metabolic Control of Th17 Cell Generation and CNS Inflammation. Journal of Neurology & Neurophysiology. PMID 25705564 DOI: 10.4172/2155-9562.S12-004  0.478
2014 Chapman NM, Chi H. mTOR Links Environmental Signals to T Cell Fate Decisions. Frontiers in Immunology. 5: 686. PMID 25653651 DOI: 10.3389/fimmu.2014.00686  0.538
2014 Chapman NM, Chi H. mTOR signaling, Tregs and immune modulation. Immunotherapy. 6: 1295-311. PMID 25524385 DOI: 10.2217/imt.14.84  0.451
2014 Shrestha S, Yang K, Wei J, Karmaus PW, Neale G, Chi H. Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs. Proceedings of the National Academy of Sciences of the United States of America. 111: 14858-63. PMID 25271321 DOI: 10.1073/pnas.1404264111  0.512
2014 Wei J, Yang K, Chi H. Cutting edge: Discrete functions of mTOR signaling in invariant NKT cell development and NKT17 fate decision. Journal of Immunology (Baltimore, Md. : 1950). 193: 4297-301. PMID 25261481 DOI: 10.4049/jimmunol.1402042  0.447
2014 Karmaus PW, Chi H. c-Myc and AP4: a relay team for metabolic reprogramming of CD8+ T cells. Nature Immunology. 15: 828-9. PMID 25137465 DOI: 10.1038/ni.2962  0.363
2014 Mahmud SA, Manlove LS, Schmitz HM, Xing Y, Wang Y, Owen DL, Schenkel JM, Boomer JS, Green JM, Yagita H, Chi H, Hogquist KA, Farrar MA. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells. Nature Immunology. 15: 473-81. PMID 24633226 DOI: 10.1038/Ni.2849  0.466
2014 Wu J, Yang J, Yang K, Wang H, Gorentla B, Shin J, Qiu Y, Que LG, Foster WM, Xia Z, Chi H, Zhong XP. iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions. The Journal of Clinical Investigation. 124: 1685-98. PMID 24614103 DOI: 10.1172/Jci69780  0.463
2014 Karmaus PW, Chi H. Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation. Cellular and Molecular Life Sciences : Cmls. 71: 1893-906. PMID 24366237 DOI: 10.1007/s00018-013-1534-7  0.335
2013 Zeng H, Chi H. The interplay between regulatory T cells and metabolism in immune regulation. Oncoimmunology. 2: e26586. PMID 24404429 DOI: 10.4161/onci.26586  0.415
2013 Yang K, Shrestha S, Zeng H, Karmaus PW, Neale G, Vogel P, Guertin DA, Lamb RF, Chi H. T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming. Immunity. 39: 1043-56. PMID 24315998 DOI: 10.1016/j.immuni.2013.09.015  0.586
2013 Wang Y, Huang G, Zeng H, Yang K, Lamb RF, Chi H. Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E4894-903. PMID 24282297 DOI: 10.1073/pnas.1308905110  0.435
2013 Yang K, Chi H. Tuning mTOR activity for immune balance. The Journal of Clinical Investigation. 123: 5001-4. PMID 24270416 DOI: 10.1172/JCI73202  0.568
2013 Negishi H, Matsuki K, Endo N, Sarashina H, Miki S, Matsuda A, Fukazawa K, Taguchi-Atarashi N, Ikushima H, Yanai H, Nishio J, Honda K, Fujioka Y, Ohba Y, Noda T, ... ... Chi H, et al. Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis. Proceedings of the National Academy of Sciences of the United States of America. 110: 19884-9. PMID 24248350 DOI: 10.1073/Pnas.1320145110  0.34
2013 Shi LZ, Chi H. Gfi1: a unique controller of T(reg) cells. Cell Cycle (Georgetown, Tex.). 12: 3581-2. PMID 24131921 DOI: 10.4161/cc.26824  0.415
2013 Shi LZ, Kalupahana NS, Turnis ME, Neale G, Hock H, Vignali DA, Chi H. Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E3198-205. PMID 23918371 DOI: 10.1073/Pnas.1300950110  0.564
2013 Zeng H, Yang K, Cloer C, Neale G, Vogel P, Chi H. mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function. Nature. 499: 485-90. PMID 23812589 DOI: 10.1038/nature12297  0.612
2013 Huang G, Wang Y, Chi H. Control of T cell fates and immune tolerance by p38α signaling in mucosal CD103+ dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 650-9. PMID 23752611 DOI: 10.4049/jimmunol.1300398  0.456
2013 Zeng H, Chi H. mTOR and lymphocyte metabolism. Current Opinion in Immunology. 25: 347-55. PMID 23722114 DOI: 10.1016/j.coi.2013.05.002  0.488
2013 Mancino A, Habbeddine M, Johnson E, Luron L, Bebien M, Memet S, Fong C, Bajenoff M, Wu X, Karin M, Caamano J, Chi H, Seed M, Lawrence T. I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection. The Embo Journal. 32: 816-28. PMID 23422957 DOI: 10.1038/emboj.2013.28  0.424
2012 Yang K, Chi H. mTOR and metabolic pathways in T cell quiescence and functional activation. Seminars in Immunology. 24: 421-8. PMID 23375549 DOI: 10.1016/j.smim.2012.12.004  0.596
2012 Callen E, Faryabi RB, Luckey M, Hao B, Daniel JA, Yang W, Sun HW, Dressler G, Peng W, Chi H, Ge K, Krangel MS, Park JH, Nussenzweig A. The DNA Damage- and Transcription-Associated Protein Paxip1 Controls Thymocyte Development and Emigration Immunity. 37: 971-985. PMID 23159437 DOI: 10.1016/J.Immuni.2012.10.007  0.359
2012 Chi H. Regulation and function of mTOR signalling in T cell fate decisions. Nature Reviews. Immunology. 12: 325-38. PMID 22517423 DOI: 10.1038/nri3198  0.582
2012 Huang G, Wang Y, Chi H. Regulation of TH17 cell differentiation by innate immune signals. Cellular & Molecular Immunology. 9: 287-95. PMID 22504954 DOI: 10.1038/cmi.2012.10  0.558
2012 Lukens JR, Barr MJ, Chaplin DD, Chi H, Kanneganti TD. Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 3107-15. PMID 22345669 DOI: 10.4049/Jimmunol.1103308  0.389
2012 Wang Y, Huang G, Vogel P, Neale G, Reizis B, Chi H. Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function. Proceedings of the National Academy of Sciences of the United States of America. 109: E343-52. PMID 22308391 DOI: 10.1073/Pnas.1115635109  0.391
2012 Huang G, Wang Y, Vogel P, Kanneganti TD, Otsu K, Chi H. Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation. Nature Immunology. 13: 152-61. PMID 22231518 DOI: 10.1038/ni.2207  0.508
2011 Wang R, Dillon CP, Shi LZ, Milasta S, Carter R, Finkelstein D, McCormick LL, Fitzgerald P, Chi H, Munger J, Green DR. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity. 35: 871-82. PMID 22195744 DOI: 10.1016/J.Immuni.2011.09.021  0.477
2011 Yang K, Neale G, Green DR, He W, Chi H. The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function. Nature Immunology. 12: 888-97. PMID 21765414 DOI: 10.1038/Ni.2068  0.433
2011 Huang G, Wang Y, Shi LZ, Kanneganti TD, Chi H. Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates. Immunity. 35: 45-58. PMID 21723158 DOI: 10.1016/j.immuni.2011.05.014  0.571
2011 Shi LZ, Wang R, Huang G, Vogel P, Neale G, Green DR, Chi H. HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. The Journal of Experimental Medicine. 208: 1367-76. PMID 21708926 DOI: 10.1084/Jem.20110278  0.516
2011 Shaw PJ, Barr MJ, Lukens JR, McGargill MA, Chi H, Mak TW, Kanneganti TD. Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity. Immunity. 34: 75-84. PMID 21236705 DOI: 10.1016/J.Immuni.2010.12.015  0.318
2010 Liu G, Yang K, Burns S, Shrestha S, Chi H. The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells. Nature Immunology. 11: 1047-56. PMID 20852647 DOI: 10.1038/ni.1939  0.504
2010 Chi H, Flavell RA. Studies on MAP Kinase signaling in the immune system. Methods in Molecular Biology (Clifton, N.J.). 661: 471-80. PMID 20812002 DOI: 10.1007/978-1-60761-795-2_29  0.487
2010 He W, Hao J, Dong S, Gao Y, Tao J, Chi H, Flavell R, O'Brien RL, Born WK, Craft J, Han J, Wang P, Zhao L, Wu J, Yin Z. Naturally activated V gamma 4 gamma delta T cells play a protective role in tumor immunity through expression of eomesodermin. Journal of Immunology (Baltimore, Md. : 1950). 185: 126-33. PMID 20525896 DOI: 10.4049/Jimmunol.0903767  0.502
2010 Shaw PJ, Lukens JR, Burns S, Chi H, McGargill MA, Kanneganti TD. Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 184: 4610-4. PMID 20368281 DOI: 10.4049/Jimmunol.1000217  0.305
2009 Bogani D, Siggers P, Brixey R, Warr N, Beddow S, Edwards J, Williams D, Wilhelm D, Koopman P, Flavell RA, Chi H, Ostrer H, Wells S, Cheeseman M, Greenfield A. Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. Plos Biology. 7: e1000196. PMID 19753101 DOI: 10.1371/Journal.Pbio.1000196  0.31
2009 Liu G, Burns S, Huang G, Boyd K, Proia RL, Flavell RA, Chi H. The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR. Nature Immunology. 10: 769-77. PMID 19483717 DOI: 10.1038/Ni.1743  0.526
2007 Menon S, Chi H, Zhang H, Deng XW, Flavell RA, Wei N. COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence. Nature Immunology. 8: 1236-45. PMID 17906629 DOI: 10.1038/Ni1514  0.499
2007 Chen L, He W, Kim ST, Tao J, Gao Y, Chi H, Intlekofer AM, Harvey B, Reiner SL, Yin Z, Flavell RA, Craft J. Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 2730-6. PMID 17312115 DOI: 10.4049/Jimmunol.178.5.2730  0.467
2006 Wan YY, Chi H, Xie M, Schneider MD, Flavell RA. The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function. Nature Immunology. 7: 851-8. PMID 16799562 DOI: 10.1038/Ni1355  0.528
2005 Gao Y, Tao J, Li MO, Zhang D, Chi H, Henegariu O, Kaech SM, Davis RJ, Flavell RA, Yin Z. JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance. Journal of Immunology (Baltimore, Md. : 1950). 175: 5783-9. PMID 16237070 DOI: 10.4049/Jimmunol.175.9.5783  0.42
2005 Chi H, Flavell RA. Cutting edge: regulation of T cell trafficking and primary immune responses by sphingosine 1-phosphate receptor 1. Journal of Immunology (Baltimore, Md. : 1950). 174: 2485-8. PMID 15728452 DOI: 10.4049/Jimmunol.174.5.2485  0.458
2004 Chi H, Lu B, Takekawa M, Davis RJ, Flavell RA. GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells. The Embo Journal. 23: 1576-86. PMID 15044949 DOI: 10.1038/Sj.Emboj.7600173  0.487
Low-probability matches (unlikely to be authored by this person)
2017 Karmaus PWF, Herrada AA, Guy C, Neale G, Dhungana Y, Long L, Vogel P, Avila J, Clish CB, Chi H. Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis. The Journal of Experimental Medicine. PMID 28784627 DOI: 10.1084/jem.20161855  0.298
2020 Chen L, Chi H, Kinashi T. Editorial: Hippo Signaling in the Immune System. Frontiers in Immunology. 11: 587514. PMID 33163003 DOI: 10.3389/fimmu.2020.587514  0.297
2011 Chi H. Sphingosine-1-phosphate and immune regulation: trafficking and beyond. Trends in Pharmacological Sciences. 32: 16-24. PMID 21159389 DOI: 10.1016/j.tips.2010.11.002  0.292
2006 Chi H, Barry SP, Roth RJ, Wu JJ, Jones EA, Bennett AM, Flavell RA. Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 103: 2274-9. PMID 16461893 DOI: 10.1073/Pnas.0510965103  0.283
2020 Hao Shi, Yan KK, Ding L, Qian C, Chi H, Yu J. Network Approaches for Dissecting the Immune System. Iscience. 23: 101354. PMID 32717640 DOI: 10.1016/J.Isci.2020.101354  0.28
2022 Shi H, Doench JG, Chi H. CRISPR screens for functional interrogation of immunity. Nature Reviews. Immunology. PMID 36481809 DOI: 10.1038/s41577-022-00802-4  0.275
2009 Huang G, Shi LZ, Chi H. Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination. Cytokine. 48: 161-9. PMID 19740675 DOI: 10.1016/j.cyto.2009.08.002  0.271
2013 Lupfer C, Thomas PG, Anand PK, Vogel P, Milasta S, Martinez J, Huang G, Green M, Kundu M, Chi H, Xavier RJ, Green DR, Lamkanfi M, Dinarello CA, Doherty PC, et al. Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nature Immunology. 14: 480-8. PMID 23525089 DOI: 10.1038/Ni.2563  0.262
2019 Wang W, Chapman NM, Zhang B, Li M, Fan M, Laribee RN, Zaidi MR, Pfeffer LM, Chi H, Wu ZH. Upregulation of PD-L1 via HMGB1-activated IRF3 and NF-kB contributes to UV radiation-induced immune suppression. Cancer Research. PMID 30737234 DOI: 10.1158/0008-5472.CAN-18-3134  0.257
2018 Wu J, Yang J, Yang K, Wang H, Gorentla B, Shin J, Qiu Y, Que LG, Foster WM, Xia Z, Chi H, Zhong XP. iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions. The Journal of Clinical Investigation. 128: 1707-1708. PMID 29608144 DOI: 10.1172/JCI120531  0.253
2017 Wu J, Yang J, Yang K, Wang H, Gorentla B, Shin J, Qiu Y, Que LG, Foster WM, Xia Z, Chi H, Zhong XP. iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions. The Journal of Clinical Investigation. 127: 4216. PMID 29091076 DOI: 10.1172/JCI98066  0.253
2021 Tan H, Blanco DB, Xie B, Li Y, Wu Z, Chi H, Peng J. Quantifying Proteome and Protein Modifications in Activated T Cells by Multiplexed Isobaric Labeling Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 2285: 297-317. PMID 33928561 DOI: 10.1007/978-1-0716-1311-5_23  0.249
2008 Chi H, Flavell RA. Acetylation of MKP-1 and the control of inflammation. Science Signaling. 1: pe44. PMID 18922786 DOI: 10.1126/Scisignal.141Pe44  0.245
2018 Chi H. Sin1-mTORC2 signaling drives glycolysis of developing thymocytes. Journal of Molecular Cell Biology. PMID 30496428 DOI: 10.1093/jmcb/mjy078  0.245
2015 Chi H, Kallies A. Metabolism and lymphocyte biology. Molecular Immunology. 68: 491. PMID 26552762 DOI: 10.1016/j.molimm.2015.10.006  0.239
2019 Yu J, Peng J, Chi H. Systems immunology: Integrating multi-omics data to infer regulatory networks and hidden drivers of immunity. Current Opinion in Systems Biology. 15: 19-29. PMID 32789283 DOI: 10.1016/J.Coisb.2019.03.003  0.207
2022 Wang Y, Chi H. Fasting as key tone for COVID immunity. Nature Metabolism. PMID 36180792 DOI: 10.1038/s42255-022-00646-1  0.206
2018 Kanneganti A, Malireddi RKS, Saavedra PHV, Vande Walle L, Van Gorp H, Kambara H, Tillman H, Vogel P, Luo HR, Xavier RJ, Chi H, Lamkanfi M. GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever. The Journal of Experimental Medicine. PMID 29793924 DOI: 10.1084/jem.20172060  0.188
2005 Chi H, Sarkisian MR, Rakic P, Flavell RA. Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development. Proceedings of the National Academy of Sciences of the United States of America. 102: 3846-51. PMID 15731347 DOI: 10.1073/Pnas.0500026102  0.187
2022 Sun X, Chi H. Tregs tango with killer cells in acute infection. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202400119. PMID 35312353 DOI: 10.1073/pnas.2202400119  0.185
2012 Hübner A, Mulholland DJ, Standen CL, Karasarides M, Cavanagh-Kyros J, Barrett T, Chi H, Greiner DL, Tournier C, Sawyers CL, Flavell RA, Wu H, Davis RJ. JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate. Proceedings of the National Academy of Sciences of the United States of America. 109: 12046-51. PMID 22753496 DOI: 10.1073/Pnas.1209660109  0.182
2020 Bai B, Wang X, Li Y, Chen PC, Yu K, Dey KK, Yarbro JM, Han X, Lutz BM, Rao S, Jiao Y, Sifford JM, Han J, Wang M, Tan H, ... ... Chi H, et al. Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. Neuron. PMID 31926610 DOI: 10.1016/J.Neuron.2019.12.015  0.171
2006 He Y, Luo Y, Tang S, Rajantie I, Salven P, Heil M, Zhang R, Luo D, Li X, Chi H, Yu J, Carmeliet P, Schaper W, Sinusas AJ, Sessa WC, et al. Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis Journal of Clinical Investigation. 116: 2344-2355. PMID 16932810 DOI: 10.1172/Jci28123  0.159
2006 Sarkisian MR, Bartley CM, Chi H, Nakamura F, Hashimoto-Torii K, Torii M, Flavell RA, Rakic P. MEKK4 signaling regulates filamin expression and neuronal migration. Neuron. 52: 789-801. PMID 17145501 DOI: 10.1016/J.Neuron.2006.10.024  0.148
2023 Dong X, Ding L, Thrasher A, Wang X, Liu J, Pan Q, Rash J, Dhungana Y, Yang X, Risch I, Li Y, Yan L, Rusch M, McLeod C, Yan KK, ... ... Chi H, et al. NetBID2 provides comprehensive hidden driver analysis. Nature Communications. 14: 2581. PMID 37142594 DOI: 10.1038/s41467-023-38335-6  0.148
2011 Liu W, Zi M, Chi H, Jin J, Prehar S, Neyses L, Cartwright EJ, Flavell RA, Davis RJ, Wang X. Deprivation of MKK7 in cardiomyocytes provokes heart failure in mice when exposed to pressure overload. Journal of Molecular and Cellular Cardiology. 50: 702-11. PMID 21284947 DOI: 10.1016/J.Yjmcc.2011.01.013  0.146
2019 Zeng H, Chi H. Metabolic sleuthing solves a rare immunodeficiency disease. Nature Immunology. 20: 1264-1266. PMID 31527832 DOI: 10.1038/s41590-019-0499-6  0.146
2019 Wang W, Chapman NM, Zhang B, Li M, Fan M, Laribee RN, Zaidi MR, Pfeffer LM, Chi H, Wu ZH. Correction: Upregulation of PD-L1 via HMGB1-Activated IRF3 and NF-κB Contributes to UV Radiation-Induced Immune Suppression. Cancer Research. 79: 5682. PMID 31676679 DOI: 10.1158/0008-5472.CAN-19-2862  0.145
2013 Keating R, Hertz T, Wehenkel M, Harris TL, Edwards BA, McClaren JL, Brown SA, Surman S, Wilson ZS, Bradley P, Hurwitz J, Chi H, Doherty PC, Thomas PG, McGargill MA. The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus. Nature Immunology. 14: 1266-76. PMID 24141387 DOI: 10.1038/Ni.2741  0.139
2022 Chi H, Zhou K, Shen L, Xu J, Li J, Chen S, Wu X, Tung TH, Shen B, Zhu H. The evaluation of the immune status of COVID-19 recovered subjects with persistent abnormal lung CT after one year: A longitudinal cohort study. International Immunopharmacology. 110: 109019. PMID 35816945 DOI: 10.1016/j.intimp.2022.109019  0.131
2018 Luo L, Chi H, Ling J. MiR-124-3p suppresses glioma aggressiveness via targeting of Fra-2. Pathology, Research and Practice. PMID 30243808 DOI: 10.1016/j.prp.2018.09.017  0.13
2008 Chi H, Flavell RA. Innate recognition of non-self nucleic acids. Genome Biology. 9: 211. PMID 18341708 DOI: 10.1186/Gb-2008-9-3-211  0.125
2007 Chi H, Flavell RA. Immunology: sensing the enemy within. Nature. 448: 423-4. PMID 17653183 DOI: 10.1038/448423A  0.121
2015 Kratochvill F, Gratz N, Qualls JE, Van De Velde LA, Chi H, Kovarik P, Murray PJ. Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner. Cancer Research. 75: 3054-64. PMID 26183929 DOI: 10.1158/0008-5472.CAN-15-0205  0.102
2022 Yang Y, Li Z, Zhong Q, Zhao L, Wang Y, Chi H. Identification and validation of a novel prognostic signature based on transcription factors in breast cancer by bioinformatics analysis. Gland Surgery. 11: 892-912. PMID 35694087 DOI: 10.21037/gs-22-267  0.076
2020 Bai B, Wang X, Li Y, Chen PC, Yu K, Dey KK, Yarbro JM, Han X, Lutz BM, Rao S, Jiao Y, Sifford JM, Han J, Wang M, Tan H, ... ... Chi H, et al. Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. Neuron. 106: 700. PMID 32437656 DOI: 10.1016/j.neuron.2020.04.031  0.074
2020 Zheng Y, Zhang Y, Chi H, Chen S, Peng M, Luo L, Chen L, Li J, Shen B, Wang D. The hemocyte counts as a potential biomarker for predicting disease progression in COVID-19: a retrospective study. Clinical Chemistry and Laboratory Medicine. PMID 32352397 DOI: 10.1515/cclm-2020-0377  0.06
2014 Fang H, Liu X, Shen L, Li F, Liu Y, Chi H, Miao H, Lu J, Bai Y. Role of mtDNA haplogroups in the prevalence of knee osteoarthritis in a southern Chinese population. International Journal of Molecular Sciences. 15: 2646-59. PMID 24534808 DOI: 10.3390/ijms15022646  0.051
2019 Krummel M, Blish C, Kuhns M, Cadwell K, Oberst A, Goldrath A, Ansel KM, Chi H, O'Connell R, Wherry EJ, Pepper M. Universal Principled Review: A Community-Driven Method to Improve Peer Review. Cell. 179: 1441-1445. PMID 31835023 DOI: 10.1016/J.Cell.2019.11.029  0.045
2014 Li S, Dai Q, Chen S, Zhang S, Liao X, Deng X, Chi H, Li F, Zhu J, Jiang Y. Xeroderma pigmentosum complementation group D (XPD) gene polymorphisms contribute to bladder cancer risk: a meta-analysis. Tumor Biology. 35: 3905-3915. PMID 24347488 DOI: 10.1007/S13277-013-1519-Z  0.042
2012 Zeng H, Chi H. Induced senescence: a cunning Fox's new trick. Blood. 120: 1965-6. PMID 22956524 DOI: 10.1182/blood-2012-07-439562  0.041
2022 Zhou K, Chi H, Wang J, Zheng Y, Pan J, Yu D, Xu J, Zhu H, Li J, Chen S, Zhao X, Wu X, Shen B, Tung TH, Luo C. Physical condition, psychological status, and posttraumatic stress disorder among recovered COVID-19 subjects: A mediation analysis. Frontiers in Psychiatry. 13: 918679. PMID 36147994 DOI: 10.3389/fpsyt.2022.918679  0.034
2021 Zhou X, Chen T, Zhang Q, Qi M, Zhang L, Du J, Chi H, Shen B, Xu X, Lu Y. De novo HBB frameshift mutation in a patient with dominant β-thalassemia major. International Journal of Laboratory Hematology. PMID 34323379 DOI: 10.1111/ijlh.13669  0.031
2022 Saravia J, Chi H. mTORC2 forms iron-clad defense to guard memory. Nature Immunology. PMID 35058617 DOI: 10.1038/s41590-021-01100-2  0.028
2020 Crotty S, Blish C, Cadwell K, Chi H, Goldrath A, Green D, Kaech SM, Krummel M, Pepper M, Rothlin CV, Wherry EJ. Reinvigorating NIH Grant Peer Review. Immunity. 52: 1-3. PMID 31940266 DOI: 10.1016/J.Immuni.2019.12.016  0.025
2023 Shen L, Chen L, Chi H, Luo L, Ruan J, Zhao X, Jiang Y, Tung TH, Zhu H, Zhou K, Shen B, Xu J. Parameters and Morphological Changes of Erythrocytes and Platelets of COVID-19 Subjects: A Longitudinal Cohort Study. Infection and Drug Resistance. 16: 1657-1668. PMID 36992967 DOI: 10.2147/IDR.S400735  0.025
2023 Zhou K, Hu B, Zhao X, Chi H, Pan J, Zheng Y, Bi X, Chen M, Xie J, Xu J, Tung TH, Shen B, Zhu H. Longitudinal observation of viral load in patients infected with Omicron variant and its relationship with clinical symptoms. Frontiers in Microbiology. 13: 1037733. PMID 36713203 DOI: 10.3389/fmicb.2022.1037733  0.017
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