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Ajay S. Yekkirala, PhD - Publications

Affiliations: 
2007-2011 Pharmacology University of Minnesota, Twin Cities, Minneapolis, MN 
 2011-2018 Neurobiology Harvard Medical School - Boston Children's Hospital 
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sprague JM, Yekkirala AS, Singh B, Tochitsky I, Stephens M, Viramontes O, Ivanis J, Biscola NP, Havton LA, Woolf CJ, Latremoliere A. Bortezomib-induced neuropathy is in part mediated by the sensitization of TRPV1 channels. Communications Biology. 6: 1228. PMID 38052846 DOI: 10.1038/s42003-023-05624-1  0.577
2021 Robinson KC, Kemény LV, Fell GL, Hermann AL, Allouche J, Ding W, Yekkirala A, Hsiao JJ, Su MY, Theodosakis N, Kozak G, Takeuchi Y, Shen S, Berenyi A, Mao J, et al. Reduced MC4R signaling alters nociceptive thresholds associated with red hair. Science Advances. 7. PMID 33811065 DOI: 10.1126/sciadv.abd1310  0.538
2020 Talbot S, Doyle B, Huang J, Wang JC, Ahmadi M, Roberson DP, Yekkirala A, Foster SL, Browne LE, Bean BP, Levy BD, Woolf CJ. Vagal sensory neurons drive mucous cell metaplasia. The Journal of Allergy and Clinical Immunology. PMID 31954778 DOI: 10.1016/J.Jaci.2020.01.003  0.637
2017 Knezevic NN, Yekkirala A, Yaksh TL. Basic/Translational Development of Forthcoming Opioid- and Nonopioid-Targeted Pain Therapeutics. Anesthesia and Analgesia. 125: 1714-1732. PMID 29049116 DOI: 10.1213/ANE.0000000000002442  0.362
2017 Yekkirala AS, Roberson DP, Bean BP, Woolf CJ. Breaking barriers to novel analgesic drug development. Nature Reviews. Drug Discovery. PMID 28983099 DOI: 10.1038/Nrd.2017.202  0.616
2017 Yekkirala AS, Roberson DP, Bean BP, Woolf CJ. Breaking barriers to novel analgesic drug development. Nature Reviews. Drug Discovery. PMID 28596533 DOI: 10.1038/Nrd.2017.87  0.631
2016 Sisignano M, Angioni C, Park CK, Meyer Dos Santos S, Jordan H, Kuzikov M, Liu D, Zinn S, Hohman SW, Schreiber Y, Zimmer B, Schmidt M, Lu R, Suo J, Zhang DD, ... ... Yekkirala AS, et al. Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791151 DOI: 10.1073/Pnas.1613246113  0.621
2016 Chandran V, Coppola G, Nawabi H, Omura T, Versano R, Huebner EA, Zhang A, Costigan M, Yekkirala A, Barrett L, Blesch A, Michaelevski I, Davis-Turak J, Gao F, Langfelder P, et al. A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program. Neuron. PMID 26898779 DOI: 10.1016/J.Neuron.2016.01.034  0.601
2013 Le Naour M, Akgün E, Yekkirala A, Lunzer MM, Powers MD, Kalyuzhny AE, Portoghese PS. Bivalent ligands that target μ opioid (MOP) and cannabinoid1 (CB1) receptors are potent analgesics devoid of tolerance. Journal of Medicinal Chemistry. 56: 5505-13. PMID 23734559 DOI: 10.1021/Jm4005219  0.588
2013 Yekkirala AS, Kalyuzhny AE, Portoghese PS. An immunocytochemical-derived correlate for evaluating the bridging of heteromeric mu-delta opioid protomers by bivalent ligands. Acs Chemical Biology. 8: 1412-6. PMID 23675763 DOI: 10.1021/Cb400113D  0.574
2013 Yekkirala AS. Two to tango: GPCR oligomers and GPCR-TRP channel interactions in nociception. Life Sciences. 92: 438-45. PMID 22771696 DOI: 10.1016/J.Lfs.2012.06.021  0.413
2012 Yekkirala AS, Banks ML, Lunzer MM, Negus SS, Rice KC, Portoghese PS. Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys. Acs Chemical Neuroscience. 3: 720-7. PMID 23019498 DOI: 10.1021/Cn300049M  0.585
2012 Metcalf MD, Yekkirala AS, Powers MD, Kitto KF, Fairbanks CA, Wilcox GL, Portoghese PS. The δ opioid receptor agonist SNC80 selectively activates heteromeric μ-δ opioid receptors. Acs Chemical Neuroscience. 3: 505-9. PMID 22860219 DOI: 10.1021/Cn3000394  0.591
2011 Yekkirala AS, Lunzer MM, McCurdy CR, Powers MD, Kalyuzhny AE, Roerig SC, Portoghese PS. N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromers. Proceedings of the National Academy of Sciences of the United States of America. 108: 5098-103. PMID 21385944 DOI: 10.1073/Pnas.1016277108  0.593
2010 Yekkirala AS, Kalyuzhny AE, Portoghese PS. Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonists. Acs Chemical Neuroscience. 1: 146-54. PMID 22816017 DOI: 10.1021/Cn9000236  0.579
2009 Zhang S, Yekkirala A, Tang Y, Portoghese PS. A bivalent ligand (KMN-21) antagonist for mu/kappa heterodimeric opioid receptors. Bioorganic & Medicinal Chemistry Letters. 19: 6978-80. PMID 19892550 DOI: 10.1016/J.Bmcl.2009.10.045  0.573
2007 Lunzer MM, Yekkirala A, Hebbel RP, Portoghese PS. Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia. Proceedings of the National Academy of Sciences of the United States of America. 104: 6061-5. PMID 17389363 DOI: 10.1073/Pnas.0700295104  0.584
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