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Bruce P. Bean - Publications

Affiliations: 
Neurobiology Harvard Medical School, Boston, MA, United States 
Area:
ion channels
Website:
http://neuro.med.harvard.edu/people/faculty/bruce-bean

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Vaelli P, Fujita A, Jo S, Zhang HB, Osorno T, Ma X, Bean BP. . Molecular Pharmacology. PMID 39322410 DOI: 10.1124/molpharm.124.000944  0.825
2024 Huang X, Lee S, Chen K, Kawaguchi R, Wiskow O, Ghosh S, Frost D, Perrault L, Pandey R, Klim JR, Boivin B, Hermawan C, Livak KJ, Geschwind DH, Wainger BJ, ... ... Bean BP, et al. Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis. Brain Communications. 6: fcae202. PMID 38911266 DOI: 10.1093/braincomms/fcae202  0.456
2023 Huang J, Fan X, Jin X, Jo S, Zhang HB, Fujita A, Bean BP, Yan N. Cannabidiol inhibits Na channels through two distinct binding sites. Nature Communications. 14: 3613. PMID 37330538 DOI: 10.1038/s41467-023-39307-6  0.789
2023 Deng T, Jovanovic VM, Tristan CA, Weber C, Chu PH, Inman J, Ryu S, Jethmalani Y, Ferreira de Sousa J, Ormanoglu P, Twumasi P, Sen C, Shim J, Jayakar S, Bear Zhang HX, ... ... Bean BP, et al. Scalable generation of sensory neurons from human pluripotent stem cells. Stem Cell Reports. 18: 1030-1047. PMID 37044067 DOI: 10.1016/j.stemcr.2023.03.006  0.304
2023 Jo S, Zhang HB, Bean BP. . Molecular Pharmacology. PMID 36635052 DOI: 10.1124/molpharm.122.000593  0.634
2022 Zhang HB, Heckman L, Niday Z, Jo S, Fujita A, Shim J, Pandey R, Al Jandal H, Jayakar S, Barrett LB, Smith J, Woolf CJ, Bean BP. Cannabidiol activates neuronal Kv7 channels. Elife. 11. PMID 35179483 DOI: 10.7554/eLife.73246  0.845
2021 Yang NJ, Isensee J, Neel DV, Quadros AU, Zhang HB, Lauzadis J, Liu SM, Shiers S, Belu A, Palan S, Marlin S, Maignel J, Kennedy-Curran A, Tong VS, Moayeri M, ... ... Bean BP, et al. Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2 DRG sensory neurons. Nature Neuroscience. PMID 34931070 DOI: 10.1038/s41593-021-00973-8  0.661
2021 Peters CH, Liu PW, Morotti S, Gantz SC, Grandi E, Bean BP, Proenza C. Bidirectional flow of the funny current (I) during the pacemaking cycle in murine sinoatrial node myocytes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34260402 DOI: 10.1073/pnas.2104668118  0.769
2021 Zhang HB, Bean BP. Cannabidiol inhibition of murine primary nociceptors: Tight binding to slow inactivated states of Nav1.8 channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34131037 DOI: 10.1523/JNEUROSCI.3216-20.2021  0.698
2021 Tochitsky I, Jo S, Andrews N, Kotoda M, Doyle B, Shim J, Talbot S, Roberson D, Lee J, Haste L, Jordan SM, Levy BD, Bean BP, Woolf CJ. Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker. British Journal of Pharmacology. PMID 33988876 DOI: 10.1111/bph.15531  0.392
2021 Niday Z, Bean BP. BK channel regulation of after-potentials and burst firing in cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33593855 DOI: 10.1523/JNEUROSCI.0192-20.2021  0.602
2020 Jo S, Bean BP. Lidocaine binding enhances inhibition of Nav1.7 channels by the sulfonamide PF-05089771. Molecular Pharmacology. PMID 32193331 DOI: 10.1124/mol.119.118380  0.503
2020 Talbot S, Doyle B, Huang J, Wang JC, Ahmadi M, Roberson DP, Yekkirala A, Foster SL, Browne LE, Bean BP, Levy BD, Woolf CJ. Vagal sensory neurons drive mucous cell metaplasia. The Journal of Allergy and Clinical Immunology. PMID 31954778 DOI: 10.1016/J.Jaci.2020.01.003  0.387
2020 Bean BP, Chakrapani S, Hibbs RE. Decision letter: Cryo-EM analysis of PIP2 regulation in mammalian GIRK channels Elife. DOI: 10.7554/Elife.60552.Sa1  0.443
2020 Mike A, Bean BP. Decision letter: Sodium channels implement a molecular leaky integrator that detects action potentials and regulates neuronal firing Elife. DOI: 10.7554/Elife.54940.Sa1  0.529
2019 Lee S, Jo S, Talbot S, Zhang HB, Kotoda M, Andrews NA, Puopolo M, Liu PW, Jacquemont T, Pascal M, Heckman LM, Jain A, Lee J, Woolf CJ, Bean BP. Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation. Elife. 8. PMID 31765298 DOI: 10.7554/Elife.48118  0.779
2019 Zheng Y, Liu P, Bai L, Trimmer JS, Bean BP, Ginty DD. Deep Sequencing of Somatosensory Neurons Reveals Molecular Determinants of Intrinsic Physiological Properties. Neuron. PMID 31248728 DOI: 10.1016/J.Neuron.2019.05.039  0.571
2019 Weyrer C, Turecek J, Niday Z, Liu PW, Nanou E, Catterall WA, Bean BP, Regehr WG. The Role of Ca2.1 Channel Facilitation in Synaptic Facilitation. Cell Reports. 26: 2289-2297.e3. PMID 30811980 DOI: 10.1016/J.Celrep.2019.01.114  0.63
2019 Lee S, Jo S, Talbot S, Zhang HB, Kotoda M, Andrews NA, Puopolo M, Liu PW, Jacquemont T, Pascal M, Heckman LM, Jain A, Lee J, Woolf CJ, Bean BP. Author response: Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation Elife. DOI: 10.7554/Elife.48118.Sa2  0.671
2019 Chanda B, Bean BP, Delemotte L. Decision letter: Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP Elife. DOI: 10.7554/Elife.47060.028  0.417
2019 Bean B. Context and Complexity: How Ionic Conductances Interact to Control Neuronal Firing Biophysical Journal. 116: 9a-10a. DOI: 10.1016/j.bpj.2018.11.087  0.366
2018 Hu W, Bean BP. Differential Control of Axonal and Somatic Resting Potential by Voltage-Dependent Conductances in Cortical Layer 5 Pyramidal Neurons. Neuron. 99: 1355. PMID 30236286 DOI: 10.1016/j.neuron.2018.08.042  0.624
2018 Hu W, Bean BP. Differential Control of Axonal and Somatic Resting Potential by Voltage-Dependent Conductances in Cortical Layer 5 Pyramidal Neurons. Neuron. PMID 29526554 DOI: 10.1016/J.Neuron.2018.02.016  0.738
2018 Bean BP, Ren D. Decision letter: Allosteric regulators selectively prevent Ca2+-feedback of CaV and NaV channels Elife. DOI: 10.7554/Elife.35222.024  0.434
2018 Morotti S, Sharpe E, Liu PW, Ellinwood N, Bean BP, Proenza C, Grandi E. Increased Contribution of Funny Current to Sinoatrial Node Firing Activity at Slow Heart Rates Biophysical Journal. 114: 473a. DOI: 10.1016/J.Bpj.2017.11.2605  0.319
2017 Liu P, Blair NT, Bean BP. Action potential broadening in capsaicin-sensitive DRG neurons from frequency-dependent reduction of Kv3 current. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28877968 DOI: 10.1523/JNEUROSCI.1703-17.2017  0.838
2017 Yekkirala AS, Roberson DP, Bean BP, Woolf CJ. Breaking barriers to novel analgesic drug development. Nature Reviews. Drug Discovery. PMID 28596533 DOI: 10.1038/Nrd.2017.87  0.316
2017 Gantz SC, Bean BP. Cell-Autonomous Excitation of Midbrain Dopamine Neurons by Endocannabinoid-Dependent Lipid Signaling. Neuron. PMID 28262417 DOI: 10.1016/J.Neuron.2017.02.025  0.762
2017 Jo S, Bean BP. Lacosamide inhibition of Nav1.7 voltage-gated sodium channels: slow binding to fast-inactivated states. Molecular Pharmacology. PMID 28119481 DOI: 10.1124/mol.116.106401  0.525
2017 Sharpe EJ, Gantz SC, Liu P, Bean BP, Proenza C. Characteristics of Ivabradine-Sensitive Currents in Mouse Sinoatrial Node Myocytes Biophysical Journal. 112: 35a-36a. DOI: 10.1016/J.Bpj.2016.11.226  0.801
2016 Wang W, Touhara KK, Weir K, Bean BP, MacKinnon R. Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels. Elife. 5. PMID 27074662 DOI: 10.7554/Elife.15751  0.768
2016 Wang W, Touhara KK, Weir K, Bean BP, MacKinnon R. Author response: Cooperative regulation by G proteins and Na+ of neuronal GIRK2 K+ channels Elife. DOI: 10.7554/Elife.15751.016  0.76
2015 Kimm T, Khaliq ZM, Bean BP. Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 16404-17. PMID 26674866 DOI: 10.1523/Jneurosci.5291-14.2015  0.877
2015 Bean BP. Pore dilation reconsidered. Nature Neuroscience. 18: 1534-5. PMID 26505561 DOI: 10.1038/nn.4148  0.358
2015 Yamada-Hanff J, Bean BP. Activation of Ih and TTX-sensitive sodium current at subthreshold voltages during CA1 pyramidal neuron firing. Journal of Neurophysiology. 114: 2376-89. PMID 26289465 DOI: 10.1152/jn.00489.2015  0.595
2015 Talbot S, Abdulnour RE, Burkett PR, Lee S, Cronin SJ, Pascal MA, Laedermann C, Foster SL, Tran JV, Lai N, Chiu IM, Ghasemlou N, DiBiase M, Roberson D, Von Hehn C, ... ... Bean BP, et al. Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation. Neuron. PMID 26119026 DOI: 10.1016/J.Neuron.2015.06.007  0.4
2015 Carter BC, Giessel AJ, Sabatini BL, Bean BP. Errata to Transient Sodium Current at Subthreshold Voltages: Activation by EPSP Waveforms [Neuron, 75, (2012), 1081-1093] Neuron. 87: 906. DOI: 10.1016/j.neuron.2015.06.009  0.465
2014 Kimm T, Bean BP. Inhibition of A-type potassium current by the peptide toxin SNX-482. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9182-9. PMID 25009251 DOI: 10.1523/JNEUROSCI.0339-14.2014  0.634
2014 Wainger BJ, Kiskinis E, Mellin C, Wiskow O, Han SS, Sandoe J, Perez NP, Williams LA, Lee S, Boulting G, Berry JD, Brown RH, Cudkowicz ME, Bean BP, Eggan K, et al. Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons. Cell Reports. 7: 1-11. PMID 24703839 DOI: 10.1016/J.Celrep.2014.03.019  0.375
2014 Liu PW, Bean BP. Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4991-5002. PMID 24695716 DOI: 10.1523/JNEUROSCI.1925-13.2014  0.647
2014 Jo S, Bean BP. Sidedness of carbamazepine accessibility to voltage-gated sodium channels. Molecular Pharmacology. 85: 381-7. PMID 24319110 DOI: 10.1124/mol.113.090472  0.579
2014 Brenneis C, Kistner K, Puopolo M, Jo S, Roberson D, Sisignano M, Segal D, Cobos EJ, Wainger BJ, Labocha S, Ferreirós N, von Hehn C, Tran J, Geisslinger G, Reeh PW, ... Bean BP, et al. Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block. British Journal of Pharmacology. 171: 438-51. PMID 24117225 DOI: 10.1111/Bph.12466  0.733
2013 Yamada-Hanff J, Bean BP. Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15011-21. PMID 24048831 DOI: 10.1523/JNEUROSCI.0577-13.2013  0.559
2013 Roberson DP, Gudes S, Sprague JM, Patoski HA, Robson VK, Blasl F, Duan B, Oh SB, Bean BP, Ma Q, Binshtok AM, Woolf CJ. Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons. Nature Neuroscience. 16: 910-8. PMID 23685721 DOI: 10.1038/Nn.3404  0.585
2013 Puopolo M, Binshtok AM, Yao GL, Oh SB, Woolf CJ, Bean BP. Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314. Journal of Neurophysiology. 109: 1704-12. PMID 23303863 DOI: 10.1152/Jn.00012.2013  0.826
2013 Brenneis C, Kistner K, Puopolo M, Segal D, Roberson D, Sisignano M, Labocha S, Ferreirós N, Strominger A, Cobos EJ, Ghasemlou N, Geisslinger G, Reeh PW, Bean BP, Woolf CJ. Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 315-26. PMID 23283344 DOI: 10.1523/Jneurosci.2804-12.2013  0.666
2012 Carter BC, Giessel AJ, Sabatini BL, Bean BP. Transient sodium current at subthreshold voltages: activation by EPSP waveforms. Neuron. 75: 1081-93. PMID 22998875 DOI: 10.1016/j.neuron.2012.08.033  0.596
2012 Liu P, Jo S, Bean BP. Modulation of neuronal sodium channels by the sea anemone peptide BDS-I. Journal of Neurophysiology. 107: 3155-67. PMID 22442564 DOI: 10.1152/Jn.00785.2011  0.678
2011 Bosmans F, Puopolo M, Martin-Eauclaire MF, Bean BP, Swartz KJ. Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors. The Journal of General Physiology. 138: 59-72. PMID 21670206 DOI: 10.1085/Jgp.201110614  0.862
2011 Jo S, Bean BP. Inhibition of neuronal voltage-gated sodium channels by brilliant blue G. Molecular Pharmacology. 80: 247-57. PMID 21536754 DOI: 10.1124/mol.110.070276  0.597
2011 Roberson DP, Binshtok AM, Blasl F, Bean BP, Woolf CJ. Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review. British Journal of Pharmacology. 164: 48-58. PMID 21457220 DOI: 10.1111/J.1476-5381.2011.01391.X  0.506
2011 Carter BC, Bean BP. Incomplete inactivation and rapid recovery of voltage-dependent sodium channels during high-frequency firing in cerebellar Purkinje neurons. Journal of Neurophysiology. 105: 860-71. PMID 21160003 DOI: 10.1152/jn.01056.2010  0.639
2010 Milescu LS, Bean BP, Smith JC. Isolation of somatic Na+ currents by selective inactivation of axonal channels with a voltage prepulse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7740-8. PMID 20519549 DOI: 10.1523/Jneurosci.6136-09.2010  0.819
2010 Khaliq ZM, Bean BP. Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7401-13. PMID 20505107 DOI: 10.1523/Jneurosci.0143-10.2010  0.854
2010 Kim HY, Kim K, Li HY, Chung G, Park CK, Kim JS, Jung SJ, Lee MK, Ahn DK, Hwang SJ, Kang Y, Binshtok AM, Bean BP, Woolf CJ, Oh SB. Selectively targeting pain in the trigeminal system. Pain. 150: 29-40. PMID 20236764 DOI: 10.1016/J.Pain.2010.02.016  0.633
2010 Cannon SC, Bean BP. Sodium channels gone wild: resurgent current from neuronal and muscle channelopathies. The Journal of Clinical Investigation. 120: 80-3. PMID 20038809 DOI: 10.1172/Jci41340  0.607
2010 Bosmans F, Puopolo M, Martin-Eauclaire M, Bean BP, Swartz KJ. Defining the Voltage Sensor Properties and Pharmacology of Nav1.9 Biophysical Journal. 98: 115a. DOI: 10.1016/J.Bpj.2009.12.4215  0.837
2009 Carter BC, Bean BP. Sodium entry during action potentials of mammalian neurons: incomplete inactivation and reduced metabolic efficiency in fast-spiking neurons. Neuron. 64: 898-909. PMID 20064395 DOI: 10.1016/j.neuron.2009.12.011  0.558
2009 Binshtok AM, Gerner P, Oh SB, Puopolo M, Suzuki S, Roberson DP, Herbert T, Wang CF, Kim D, Chung G, Mitani AA, Wang GK, Bean BP, Woolf CJ. Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents. Anesthesiology. 111: 127-37. PMID 19512868 DOI: 10.1097/Aln.0B013E3181A915E7  0.746
2009 Bean BP. Inhibition by an excitatory conductance: a paradox explained. Nature Neuroscience. 12: 530-2. PMID 19396231 DOI: 10.1038/nn0509-530  0.547
2008 Binshtok AM, Wang H, Zimmermann K, Amaya F, Vardeh D, Shi L, Brenner GJ, Ji RR, Bean BP, Woolf CJ, Samad TA. Nociceptors are interleukin-1beta sensors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14062-73. PMID 19109489 DOI: 10.1523/JNEUROSCI.3795-08.2008  0.352
2008 Gerner P, Binshtok AM, Wang CF, Hevelone ND, Bean BP, Woolf CJ, Wang GK. Capsaicin combined with local anesthetics preferentially prolongs sensory/nociceptive block in rat sciatic nerve. Anesthesiology. 109: 872-8. PMID 18946300 DOI: 10.1097/ALN.0b013e31818958f7  0.385
2008 Khaliq ZM, Bean BP. Dynamic, nonlinear feedback regulation of slow pacemaking by A-type potassium current in ventral tegmental area neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10905-17. PMID 18945898 DOI: 10.1523/Jneurosci.2237-08.2008  0.835
2007 Binshtok AM, Bean BP, Woolf CJ. Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. Nature. 449: 607-10. PMID 17914397 DOI: 10.1038/nature06191  0.594
2007 Jackson AC, Bean BP. State-dependent enhancement of subthreshold A-type potassium current by 4-aminopyridine in tuberomammillary nucleus neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10785-96. PMID 17913912 DOI: 10.1523/JNEUROSCI.0935-07.2007  0.796
2007 Bean BP. Neurophysiology: stressful pacemaking. Nature. 447: 1059-60. PMID 17597746 DOI: 10.1038/4471059a  0.34
2007 Bean BP. The action potential in mammalian central neurons. Nature Reviews. Neuroscience. 8: 451-65. PMID 17514198 DOI: 10.1038/nrn2148  0.609
2007 Puopolo M, Raviola E, Bean BP. Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 645-56. PMID 17234596 DOI: 10.1523/Jneurosci.4341-06.2007  0.789
2007 Martina M, Metz AE, Bean BP. Voltage-dependent potassium currents during fast spikes of rat cerebellar Purkinje neurons: inhibition by BDS-I toxin. Journal of Neurophysiology. 97: 563-71. PMID 17065256 DOI: 10.1152/Jn.00269.2006  0.772
2005 Puopolo M, Bean BP, Raviola E. Spontaneous activity of isolated dopaminergic periglomerular cells of the main olfactory bulb. Journal of Neurophysiology. 94: 3618-27. PMID 16033943 DOI: 10.1152/Jn.00225.2005  0.707
2005 Swensen AM, Bean BP. Robustness of burst firing in dissociated purkinje neurons with acute or long-term reductions in sodium conductance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3509-20. PMID 15814781 DOI: 10.1523/Jneurosci.3929-04.2005  0.595
2005 Bean BP. The molecular machinery of resurgent sodium current revealed. Neuron. 45: 185-7. PMID 15664169 DOI: 10.1016/j.neuron.2005.01.006  0.635
2005 McDonough SI, Mori Y, Bean BP. FPL 64176 modification of Ca(V)1.2 L-type calcium channels: dissociation of effects on ionic current and gating current. Biophysical Journal. 88: 211-23. PMID 15501945 DOI: 10.1529/biophysj.104.051714  0.623
2004 Jackson AC, Yao GL, Bean BP. Mechanism of spontaneous firing in dorsomedial suprachiasmatic nucleus neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7985-98. PMID 15371499 DOI: 10.1523/JNEUROSCI.2146-04.2004  0.77
2004 Do MT, Bean BP. Sodium currents in subthalamic nucleus neurons from Nav1.6-null mice. Journal of Neurophysiology. 92: 726-33. PMID 15056687 DOI: 10.1152/jn.00186.2004  0.625
2003 Blair NT, Bean BP. Role of tetrodotoxin-resistant Na+ current slow inactivation in adaptation of action potential firing in small-diameter dorsal root ganglion neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10338-50. PMID 14614093 DOI: 10.1523/Jneurosci.23-32-10338.2003  0.849
2003 Swensen AM, Bean BP. Ionic mechanisms of burst firing in dissociated Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9650-63. PMID 14573545 DOI: 10.1523/Jneurosci.23-29-09650.2003  0.589
2003 Do MT, Bean BP. Subthreshold sodium currents and pacemaking of subthalamic neurons: modulation by slow inactivation. Neuron. 39: 109-20. PMID 12848936 DOI: 10.1016/S0896-6273(03)00360-X  0.551
2003 Martina M, Yao GL, Bean BP. Properties and functional role of voltage-dependent potassium channels in dendrites of rat cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5698-707. PMID 12843273 DOI: 10.1523/Jneurosci.23-13-05698.2003  0.764
2002 Blair NT, Bean BP. Roles of tetrodotoxin (TTX)-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10277-90. PMID 12451128 DOI: 10.1523/Jneurosci.22-23-10277.2002  0.865
2002 Mitterdorfer J, Bean BP. Potassium currents during the action potential of hippocampal CA3 neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10106-15. PMID 12451111 DOI: 10.1523/Jneurosci.22-23-10106.2002  0.61
2002 McDonough SI, Boland LM, Mintz IM, Bean BP. Interactions among toxins that inhibit N-type and P-type calcium channels. The Journal of General Physiology. 119: 313-28. PMID 11929883 DOI: 10.1085/jgp.20028560  0.839
2002 Taddese A, Bean BP. Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons. Neuron. 33: 587-600. PMID 11856532 DOI: 10.1016/S0896-6273(02)00574-3  0.88
2001 Raman IM, Bean BP. Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: evidence for two mechanisms. Biophysical Journal. 80: 729-37. PMID 11159440 DOI: 10.1016/S0006-3495(01)76052-3  0.864
2000 Greif GJ, Sodickson DL, Bean BP, Neer EJ, Mende U. Altered regulation of potassium and calcium channels by GABA(B) and adenosine receptors in hippocampal neurons from mice lacking Galpha(o). Journal of Neurophysiology. 83: 1010-8. PMID 10669512 DOI: 10.1152/Jn.2000.83.2.1010  0.453
2000 Taddese A, Bean B. Stochastic firing of central neurons from stochastic gating of ion channels Annals of Biomedical Engineering. 28: S-109.  0.842
1999 Raman IM, Bean BP. Properties of sodium currents and action potential firing in isolated cerebellar Purkinje neurons. Annals of the New York Academy of Sciences. 868: 93-6. PMID 10414287 DOI: 10.1111/j.1749-6632.1999.tb11279.x  0.811
1999 Burgess DL, Biddlecome GH, McDonough SI, Diaz ME, Zilinski CA, Bean BP, Campbell KP, Noebels JL. beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain. Molecular and Cellular Neurosciences. 13: 293-311. PMID 10328888 DOI: 10.1006/Mcne.1999.0748  0.365
1999 Raman IM, Bean BP. Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1663-74. PMID 10024353 DOI: 10.1523/Jneurosci.19-05-01663.1999  0.835
1998 McDonough SI, Bean BP. Mibefradil inhibition of T-type calcium channels in cerebellar purkinje neurons. Molecular Pharmacology. 54: 1080-7. PMID 9855637 DOI: 10.1124/Mol.54.6.1080  0.638
1998 Sodickson DL, Bean BP. Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8153-62. PMID 9763462 DOI: 10.1523/Jneurosci.18-20-08153.1998  0.524
1998 Feigenspan A, Gustincich S, Bean BP, Raviola E. Spontaneous activity of solitary dopaminergic cells of the retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6776-89. PMID 9712649 DOI: 10.1523/Jneurosci.18-17-06776.1998  0.622
1997 McDonough SI, Lampe RA, Keith RA, Bean BP. Voltage-dependent inhibition of N- and P-type calcium channels by the peptide toxin omega-grammotoxin-SIA. Molecular Pharmacology. 52: 1095-104. PMID 9415720 DOI: 10.1124/Mol.52.6.1095  0.662
1997 Raman IM, Sprunger LK, Meisler MH, Bean BP. Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn8a mutant mice. Neuron. 19: 881-91. PMID 9354334 DOI: 10.1016/S0896-6273(00)80969-1  0.837
1997 Raman IM, Bean BP. Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4517-26. PMID 9169512 DOI: 10.1523/Jneurosci.17-12-04517.1997  0.864
1997 McDonough SI, Mintz IM, Bean BP. Alteration of P-type calcium channel gating by the spider toxin omega-Aga-IVA. Biophysical Journal. 72: 2117-28. PMID 9129813 DOI: 10.1016/S0006-3495(97)78854-4  0.864
1996 Sodickson DL, Bean BP. GABAB receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6374-85. PMID 8815916 DOI: 10.1523/Jneurosci.16-20-06374.1996  0.465
1996 McDonough SI, Swartz KJ, Mintz IM, Boland LM, Bean BP. Inhibition of calcium channels in rat central and peripheral neurons by omega-conotoxin MVIIC. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2612-23. PMID 8786437 DOI: 10.1523/Jneurosci.16-08-02612.1996  0.85
1995 Cardozo DL, Bean BP. Voltage-dependent calcium channels in rat midbrain dopamine neurons: modulation by dopamine and GABAB receptors. Journal of Neurophysiology. 74: 1137-48. PMID 7500139 DOI: 10.1152/Jn.1995.74.3.1137  0.583
1994 Sah DW, Bean BP. Inhibition of P-type and N-type calcium channels by dopamine receptor antagonists. Molecular Pharmacology. 45: 84-92. PMID 8302284  0.448
1994 Kuo CC, Bean BP. Na+ channels must deactivate to recover from inactivation. Neuron. 12: 819-29. PMID 8161454 DOI: 10.1016/0896-6273(94)90335-2  0.715
1994 Boland LM, Morrill JA, Bean BP. omega-Conotoxin block of N-type calcium channels in frog and rat sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 5011-27. PMID 8046465 DOI: 10.1523/Jneurosci.14-08-05011.1994  0.62
1994 Kuo CC, Bean BP. Slow binding of phenytoin to inactivated sodium channels in rat hippocampal neurons. Molecular Pharmacology. 46: 716-25. PMID 7969051  0.687
1993 Kuo CC, Bean BP. G-protein modulation of ion permeation through N-type calcium channels. Nature. 365: 258-62. PMID 8396731 DOI: 10.1038/365258A0  0.685
1993 Mintz IM, Bean BP. GABAB receptor inhibition of P-type Ca2+ channels in central neurons. Neuron. 10: 889-98. PMID 8388225 DOI: 10.1016/0896-6273(93)90204-5  0.828
1993 Swartz KJ, Merritt A, Bean BP, Lovinger DM. Protein kinase C modulates glutamate receptor inhibition of Ca2+ channels and synaptic transmission. Nature. 361: 165-8. PMID 8380626 DOI: 10.1038/361165a0  0.41
1993 Adams ME, Mintz IM, Reily MD, Thanabal V, Bean BP. Structure and properties of omega-agatoxin IVB, a new antagonist of P-type calcium channels. Molecular Pharmacology. 44: 681-8. PMID 8232218  0.805
1993 Mintz IM, Bean BP. Block of calcium channels in rat neurons by synthetic omega-Aga-IVA. Neuropharmacology. 32: 1161-9. PMID 8107970 DOI: 10.1016/0028-3908(93)90010-Z  0.846
1993 Boland LM, Bean BP. Modulation of N-type calcium channels in bullfrog sympathetic neurons by luteinizing hormone-releasing hormone: kinetics and voltage dependence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 516-33. PMID 7678856 DOI: 10.1523/Jneurosci.13-02-00516.1993  0.626
1992 Bean BP. Pharmacology and electrophysiology of ATP-activated ion channels. Trends in Pharmacological Sciences. 13: 87-90. PMID 1374198 DOI: 10.1016/0165-6147(92)90032-2  0.463
1992 Swartz KJ, Bean BP. Inhibition of calcium channels in rat CA3 pyramidal neurons by a metabotropic glutamate receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4358-71. PMID 1359036 DOI: 10.1523/Jneurosci.12-11-04358.1992  0.517
1992 Hillyard DR, Monje VD, Mintz IM, Bean BP, Nadasdi L, Ramachandran J, Miljanich G, Azimi-Zoonooz A, McIntosh JM, Cruz LJ. A new Conus peptide ligand for mammalian presynaptic Ca2+ channels. Neuron. 9: 69-77. PMID 1352986 DOI: 10.1016/0896-6273(92)90221-X  0.792
1992 Bean BP. Whole-cell recording of calcium channel currents. Methods in Enzymology. 207: 181-93. PMID 1326702 DOI: 10.1016/0076-6879(92)07013-E  0.542
1992 Mintz IM, Adams ME, Bean BP. P-type calcium channels in rat central and peripheral neurons. Neuron. 9: 85-95. PMID 1321648 DOI: 10.1016/0896-6273(92)90223-Z  0.835
1992 Mintz IM, Venema VJ, Swiderek KM, Lee TD, Bean BP, Adams ME. P-type calcium channels blocked by the spider toxin omega-Aga-IVA. Nature. 355: 827-9. PMID 1311418 DOI: 10.1038/355827A0  0.829
1992 BEAN B. $beta;-Adrenergic modulation of cardiac calcium channels Journal of Molecular and Cellular Cardiology. 24: 9. DOI: 10.1016/0022-2828(92)93402-6  0.314
1991 Regan LJ, Sah DW, Bean BP. Ca2+ channels in rat central and peripheral neurons: high-threshold current resistant to dihydropyridine blockers and omega-conotoxin. Neuron. 6: 269-80. PMID 1847065 DOI: 10.1016/0896-6273(91)90362-4  0.618
1991 Mintz IM, Venema VJ, Adams ME, Bean BP. Inhibition of N- and L-type Ca2+ channels by the spider venom toxin omega-Aga-IIIA. Proceedings of the National Academy of Sciences of the United States of America. 88: 6628-31. PMID 1713686 DOI: 10.1073/pnas.88.15.6628  0.822
1991 Bean BP. Pharmacology of calcium channels in cardiac muscle, vascular muscle, and neurons. American Journal of Hypertension. 4: 406S-411S. PMID 1654934 DOI: 10.1093/ajh/4.7.406S  0.581
1990 Friel DD, Bean BP. Dual control by ATP and acetylcholine of inwardly rectifying K+ channels in bovine atrial cells. PflüGers Archiv : European Journal of Physiology. 415: 651-7. PMID 2336344 DOI: 10.1007/BF02584001  0.731
1990 Bean B. Gating for the physiologist Nature. 348: 192-193. PMID 1978254 DOI: 10.1038/348192a0  0.413
1990 Bean BP, Friel DD. ATP-activated channels in excitable cells. Ion Channels. 2: 169-203. PMID 1715204  0.732
1990 Bean BP, Williams CA, Ceelen PW. ATP-activated channels in rat and bullfrog sensory neurons: current-voltage relation and single-channel behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 11-9. PMID 1688930 DOI: 10.1523/Jneurosci.10-01-00011.1990  0.641
1990 Bean BP. ATP-activated channels in rat and bullfrog sensory neurons: concentration dependence and kinetics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 1-10. PMID 1688928 DOI: 10.1523/Jneurosci.10-01-00001.1990  0.513
1989 Bean BP. Multiple types of calcium channels in heart muscle and neurons. Modulation by drugs and neurotransmitters. Annals of the New York Academy of Sciences. 560: 334-45. PMID 2568109 DOI: 10.1111/j.1749-6632.1989.tb24113.x  0.488
1989 Bean BP. Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence. Nature. 340: 153-6. PMID 2567963 DOI: 10.1038/340153a0  0.668
1989 Bean BP, Rios E. Nonlinear charge movement in mammalian cardiac ventricular cells. Components from Na and Ca channel gating. The Journal of General Physiology. 94: 65-93. PMID 2553859 DOI: 10.1085/Jgp.94.1.65  0.5
1989 Bean BP. Classes of calcium channels in vertebrate cells. Annual Review of Physiology. 51: 367-84. PMID 2540697 DOI: 10.1146/annurev.ph.51.030189.002055  0.503
1989 Bean B. More than a Ca2+ channel? Trends in Neurosciences. 12: 128-130. PMID 2470169 DOI: 10.1016/0166-2236(89)90050-7  0.458
1988 Friel DD, Bean BP. Two ATP-activated conductances in bullfrog atrial cells. The Journal of General Physiology. 91: 1-27. PMID 3257791 DOI: 10.1085/Jgp.91.1.1  0.718
1988 Huettner JE, Bean BP. Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels. Proceedings of the National Academy of Sciences of the United States of America. 85: 1307-11. PMID 2448800 DOI: 10.1073/Pnas.85.4.1307  0.726
1987 Bean BP, Sturek M, Puga A, Hermsmeyer K. Nitrendipine block of calcium channels in cardiac and vascular muscle Journal of Cardiovascular Pharmacology. 9: S17-S24. DOI: 10.1097/00005344-198700094-00004  0.433
1986 Triggle DJ, Lazdunski M, Bean BP. [Calcium channels and calcium antagonists]. Medizinische Monatsschrift FüR Pharmazeuten. 9: 363-4. PMID 2433568  0.329
1986 Tsien RW, Bean BP, Hess P, Lansman JB, Nilius B, Nowycky MC. Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists. Journal of Molecular and Cellular Cardiology. 18: 691-710. PMID 2427730 DOI: 10.1016/S0022-2828(86)80941-5  0.816
1986 Bean BP, Sturek M, Puga A, Hermsmeyer K. Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs. Circulation Research. 59: 229-35. PMID 2427250 DOI: 10.1161/01.Res.59.2.229  0.583
1986 Bean BP. Calcium channels in skeletal muscle: what do they do? Trends in Neurosciences. 9: 535-536. DOI: 10.1016/0166-2236(86)90168-2  0.426
1985 Bean BP. Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology. The Journal of General Physiology. 86: 1-30. PMID 2411846  0.488
1984 Cohen CJ, Bean BP, Tsien RW. Maximal upstroke velocity as an index of available sodium conductance. Comparison of maximal upstroke velocity and voltage clamp measurements of sodium current in rabbit Purkinje fibers. Circulation Research. 54: 636-51. PMID 6329543 DOI: 10.1161/01.Res.54.6.636  0.724
1984 Bean BP, Nowycky MC, Tsien RW. Beta-adrenergic modulation of calcium channels in frog ventricular heart cells. Nature. 307: 371-5. PMID 6320002 DOI: 10.1038/307371a0  0.669
1984 Bean BP. Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state. Proceedings of the National Academy of Sciences of the United States of America. 81: 6388-92. PMID 6093100 DOI: 10.1073/Pnas.81.20.6388  0.464
1983 Tsien RW, Bean BP, Hess P, Nowycky M. Calcium channels: mechanisms of beta-adrenergic modulation and ion permeation. Cold Spring Harbor Symposia On Quantitative Biology. 48: 201-12. PMID 6327154 DOI: 10.1101/Sqb.1983.048.01.023  0.687
1983 Bean BP, Cohen CJ, Tsien RW. Lidocaine block of cardiac sodium channels. The Journal of General Physiology. 81: 613-42. PMID 6306139 DOI: 10.1085/Jgp.81.5.613  0.718
1981 Cohen CJ, Bean BP, Colatsky TJ, Tsien RW. Tetrodotoxin block of sodium channels in rabbit Purkinje fibers. Interactions between toxin binding and channel gating. The Journal of General Physiology. 78: 383-411. PMID 6270235 DOI: 10.1085/Jgp.78.4.383  0.734
1981 Bean BP. Sodium channel inactivation in the crayfish giant axon. Must channels open before inactivating? Biophysical Journal. 35: 595-614. PMID 6268217 DOI: 10.1016/S0006-3495(81)84815-1  0.591
1981 Bean BP, Shrager P, Goldstein DA. Modification of sodium and potassium channel gating kinetics by ether and halothane. The Journal of General Physiology. 77: 233-53. PMID 6265590 DOI: 10.1085/Jgp.77.3.233  0.799
1981 Bean BP, Cohen CJ, Tsien RW. Lidocaine binding to resting and inactivated cardiac sodium channels Biophysical Journal. 33: T-PM-D6.  0.612
1980 Bean BP, Cohen CJ, Colatsky TJ, Tsien RW. Concentration-dependence of tetrodotoxin action on sodium currents and maximal upstroke velocity in rabbit cardiac Purkinje fibres Journal of Physiology. 23P.  0.532
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