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High-probability grants
According to our matching algorithm, Lloyd M Beidler is the likely recipient of the following grants.
| Years |
Recipients |
Code |
Title / Keywords |
Matching
score |
| 1985 — 1990 |
Beidler, Lloyd M. |
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
Responses From Chorda Tympani &Glossopharyngeal Nerves @ Florida State University
A comparison of taste responses from the fungiform, foliate and circumvallate papillae will be studied by simultaneous recording from the chorda tympani and glossopharyngeal nerves. Hypoglossal stimulation will be used to increase the transport rate of the taste stimulus to the taste buds of the circumvallate and foliate papillae by mechanical movement of the tongue. The effectiveness of a variety of bitter stimuli will be measured by response-concentration functions. The hypothesis that "the relative reactivity of taste receptor cells to different chemicals is determined by inherent properties of the tissue from which the cells are formed" will be tested by simultaneous recording of chorda tympani and glossopharyngeal nerve bundles that innervate the foliate papillae. The taste system is excellent for study of the general problem of molecule-cell interactions that are so important in biology and medicine. Since the taste cells are rapidly renewed, the process of cell differentiation can also be studied by examining the importance of nerve contact in taste cell differentiation. Bitterness is of great importance in the development of both rodenticides and medicines.
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1 |
| 1985 — 1986 |
Beidler, Lloyd |
N/AActivity Code Description:
No activity code was retrieved: click on the grant title for more information |
U.S.-Japan Joint Seminar: Taste Cell Transduction/ Shimoda, Japan/September, 1985 @ Florida State University |
0.915 |
| 1987 — 1991 |
Beidler, Lloyd M. |
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
Effect of Age On Taste @ Florida State University
The objective is to understand the role of taste cell renewal in the aging process. Food identification difficulties and a lack of proper nutrition have been noted in the elderly. The role of taste in these deficiencies is not understood. A likely physiological change in taste for the elderly is a slowing down of taste cell renewal. The relationship between taste perception and taste cell renewal is not known. The specific aims are: (1) Compare taste cell renewal in young and old Fischer-344 rats. (2) Simultaneously, the functioning of the taste system of young and old rats will be studies to note any decrease in sensitivity with age, using a comprehensive analysis of behavior in the presence of a variety of tastants and by electrophysiological recordings from peripheral taste nerves, including those from the palate. (3) Finally, changes in taste bud renewal will be experimentally introduced by injecting vinblastine sulfate, which arrests mitosis in its metaphase and by injecting testosterone, which alters the life cycle of the taste cells. The effects of these changes will be measured both by recording the neural changes in the taste nerves and by thoroughly studying the taste behavior of the rat.
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1 |