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High-probability grants
According to our matching algorithm, Richard W. Briggs is the likely recipient of the following grants.
| Years |
Recipients |
Code |
Title / Keywords |
Matching
score |
| 1985 — 1987 |
Briggs, Richard W. |
R23Activity Code Description:
Undocumented code - click on the grant title for more information. |
Rf Coil Design For Biological Nuclear Magnetic Resonance @ Pennsylvania State Univ Hershey Med Ctr
LONG-TERM OBJECTIVES 1. To calculate magnetic field profiles of NMR coils of different geometries, and the signal detected by them from different regions in space with various pulse sequences. 2. To use this information to design tailor-made NMR coils with good homogeneity and spatial selectivity properties for specific in vivo organs and tissue. This will hopefully allow better discrimination of signal from desired tissue vs. undesired tissue, better signal-to-noise ratio, and more reliable measurements of relaxation times and kinetics. SPECIFIC AIMS 1. To calculate and graphically display radiofrequency magnetic field profiles and contours generated by NMR coils of various geometries. To calculate and display signal intensities obtained from different regions of a sample with these coils using different commonly employed pulse sequences as a function of RF power and pulse duration and inter-pulse delay time. 2. To use such information to design transmitter and receiver coils with desired properties of field homogeneity, spatial selectivity, and sensitivity for applications in in vivo biological nuclear magnetic resonance (NMR). 3. To verify these calculations with experimental data from phantom samples and coils constructed to geometrical specifications suggested by theory. 4. To build coils of successful geometries to be compatible with in vivo physiology and anatomy, and apply them to study metabolism. METHODOLOGY 1. Write software to perform the calculations and graphics displays on a VAX 11/780, using the Biot Law. 2. Construct coils from materials selected for biocompatibility and electromagnetic performance. Measure induced fields on bench with synthesizer, oscilloscope, and search coil. Measure S/N on spectrometer with phantoms at different spatial locations. 3. Apply coils to study of in vivo metabolism of selected organs, viz., brain, heart, and kidney.
|
0.964 |
| 2000 — 2002 |
Briggs, Richard W. |
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes. |
Core--Neuroimaging
The purpose of Neuroimaging Core B is to provide the subprojects of this program project grant with the facilities, technical expertise, and methodology, to successfully apply fMRI to the study and treatment of aphasia and related disorders caused by stroke and other neurological disorders. This will include all aspects of data acquisition (including interface of task presentation and performance monitoring with the MR scanning), data transfer, data archiving, and data analysis (including statistics). In particular, it will be the function of the core to provide optimized MRI sequences for anatomic, angiographic and functional images of the brain for subjects selected for fMRI. In this program project proposal, fMRI will be used by the various subprojects to answer two types of questions. Every fMRI component of the subprojects in this proposal will address one or both of the following questions for the relevant language and cognitive functions. (1) How do damaged brain systems operate differently from normal brain systems in performing various tasks? To answer this question, functional brain maps of brain- damaged patients will be compared to those of neurologically normal controls on relevant cognitive tasks. (2) How does rehabilitation change brain systems responsible for relevant cognitive activities in brain- damaged individuals? To anser this question, functional brain maps will be acquired for relevant cognitive activities before and after the individual patient receives rehabilitation.
|
0.964 |
