Brian G. Ciruna, Ph.D.

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Stem cell research, Molecular genetics, Developmental biology
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"Brian Ciruna"
Mean distance: 19.4 (cluster 57)
 

Parents

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Janet Rossant grad student 2001 University of Toronto
 (The role of FGFR1 signalling in the specification and morphogenesis of mesoderm during mouse gastrulation.)
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Publications

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Ali RQ, Meyer-Miner A, David-Rachel M, et al. (2023) Loss of a cilia-associated gene, pkd1l1, causes biliary defects in zebrafish: Implications for Biliary Atresia Splenic Malformation. Disease Models & Mechanisms
Rebello D, Wohler E, Erfani V, et al. (2023) COL11A2 as a candidate gene for vertebral malformations and congenital scoliosis. Human Molecular Genetics
Jussila M, Boswell CW, Griffiths NW, et al. (2022) Live imaging and conditional disruption of native PCP activity using endogenously tagged zebrafish sfGFP-Vangl2. Nature Communications. 13: 5598
Meyer-Miner A, Van Gennip JLM, Henke K, et al. (2022) Resolving primary pathomechanisms driving idiopathic-like spinal curvature using a new scoliosis model. Iscience. 25: 105028
Tsatskis Y, Rosenfeld R, Pearson JD, et al. (2020) The NEMP family supports metazoan fertility and nuclear envelope stiffness. Science Advances. 6: eabb4591
Rose CD, Pompili D, Henke K, et al. (2020) SCO-Spondin Defects and Neuroinflammation Are Conserved Mechanisms Driving Spinal Deformity across Genetic Models of Idiopathic Scoliosis. Current Biology : Cb
Hengel H, Bosso-Lefèvre C, Grady G, et al. (2020) Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy. Nature Communications. 11: 595
Van Gennip JLM, Boswell CW, Ciruna B. (2018) Neuroinflammatory signals drive spinal curve formation in zebrafish models of idiopathic scoliosis. Science Advances. 4: eaav1781
Konjikusic MJ, Yeetong P, Boswell CW, et al. (2018) Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development. Plos Genetics. 14: e1007817
Jussila M, Ciruna B. (2017) Zebrafish models of non-canonical Wnt/planar cell polarity signalling: fishing for valuable insight into vertebrate polarized cell behavior. Wiley Interdisciplinary Reviews. Developmental Biology. 6
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