Thuc Le, Ph.D.

Affiliations: 
Neuroscience University of California, Los Angeles, Los Angeles, CA 
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"Thuc Le"
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Guoping Fan grad student 2013 UCLA
 (The Regulation of DNA Methylation and Hydroxymethylation in Postmitotic Neurons and Other Mammalian Cells.)
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Publications

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Dao B, Trinh VN, Nguyen HV, et al. (2024) Crosstalk between genomic variants and DNA methylation in FLT3 mutant acute myeloid leukemia. Briefings in Functional Genomics
Aguilera KY, Riahi R, Saadat EA, et al. (2019) Abstract C01: Porcupine inhibition redirects mitochondrial metabolism in Wnt-dependent pancreatic cancer Cancer Research. 79
Kollareddy M, Dimitrova E, Vallabhaneni KC, et al. (2015) Regulation of nucleotide metabolism by mutant p53 contributes to its gain-of-function activities. Nature Communications. 6: 7389
Feng J, Shao N, Szulwach KE, et al. (2015) Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature Neuroscience. 18: 536-44
Huang K, Wu Z, Liu Z, et al. (2014) Selective demethylation and altered gene expression are associated with ICF syndrome in human-induced pluripotent stem cells and mesenchymal stem cells. Human Molecular Genetics. 23: 6448-57
Sun D, Luo M, Jeong M, et al. (2014) Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell. 14: 673-88
Dawlaty MM, Breiling A, Le T, et al. (2014) Loss of Tet enzymes compromises proper differentiation of embryonic stem cells. Developmental Cell. 29: 102-11
Guo JU, Su Y, Shin JH, et al. (2014) Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nature Neuroscience. 17: 215-22
Rudenko A, Dawlaty MM, Seo J, et al. (2013) Tet1 is critical for neuronal activity-regulated gene expression and memory extinction. Neuron. 79: 1109-22
Vincent JJ, Huang Y, Chen PY, et al. (2013) Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell. 12: 470-8
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