Joseph W. Lewcock, Ph.D.
Affiliations: | Johns Hopkins University, Baltimore, MD |
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"Joseph Lewcock"Mean distance: 17.65 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Randall R. Reed | grad student | 2004 | Johns Hopkins | |
| (Molecular mechanisms regulating mono -allelic odorant receptor expression.) | ||||
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Publications
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| Andreone BJ, Przybyla L, Llapashtica C, et al. (2020) Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia. Nature Neuroscience |
| Nugent AA, Lin K, van Lengerich B, et al. (2019) TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge. Neuron |
| Andreone BJ, Larhammar M, Lewcock JW. (2019) Cell Death and Neurodegeneration. Cold Spring Harbor Perspectives in Biology |
| Fang MY, Markmiller S, Vu AQ, et al. (2019) Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron |
| Bonanomi D, Valenza F, Chivatakarn O, et al. (2019) p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts. Neuron |
| Newton K, Dugger DL, Sengupta-Ghosh A, et al. (2018) Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain. Proceedings of the National Academy of Sciences of the United States of America |
| Siu M, Sengupta Ghosh A, Lewcock JW. (2018) Dual Leucine Zipper Kinase Inhibitors for the Treatment of Neurodegeneration. Journal of Medicinal Chemistry |
| Larhammar M, Huntwork-Rodriguez S, Rudhard Y, et al. (2017) The Ste20 family kinases MAP4K4, MINK1 and TNIK, converge to regulate stress induced JNK signaling in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
| Patel S, Meilandt WJ, Erickson RI, et al. (2017) Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's Disease. Journal of Medicinal Chemistry |
| Le Pichon CE, Meilandt WJ, Dominguez S, et al. (2017) Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease. Science Translational Medicine. 9 |