Lili Wan, Ph.D.

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Spinal Muscular Atrophy, RNA binding proteins, Splicing, High-Throughput Screening
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"Lili Wan"
Mean distance: 17.41 (cluster 11)
 
SNBCP

Parents

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Gideon Dreyfuss grad student 2001 Penn
 (Functional diversity of the RNA -binding proteins from the nucleus to the cytoplasm.)
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Publications

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Oh JM, Venters CC, Di C, et al. (2020) U1 snRNP regulates cancer cell migration and invasion in vitro. Nature Communications. 11: 1
Li D, Zhang J, Wang M, et al. (2018) Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation. Nature Communications. 9: 1726
Oh JM, Di C, Venters CC, et al. (2017) U1 snRNP telescripting regulates a size-function-stratified human genome. Nature Structural & Molecular Biology
Wan L, Dreyfuss G. (2017) Splicing-Correcting Therapy for SMA. Cell. 170: 5
So BR, Wan L, Zhang Z, et al. (2016) A U1 snRNP-specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange. Nature Structural & Molecular Biology
Zhang Z, Pinto AM, Wan L, et al. (2013) Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 110: 19348-53
Younis I, Dittmar K, Wang W, et al. (2013) Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA. Elife. 2: e00780
Younis I, Dittmar K, Wang W, et al. (2013) Author response: Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA Elife
Berg MG, Singh LN, Younis I, et al. (2012) U1 snRNP determines mRNA length and regulates isoform expression. Cell. 150: 53-64
Berg MG, Wan L, Younis I, et al. (2012) A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis. Molecular and Cellular Biology. 32: 1271-83
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