Travis L. Biechele, Ph.D.
Affiliations: | University of Washington, Seattle, Seattle, WA |
Area:
Wnt signalingGoogle:
"Travis Biechele"Mean distance: 17.6 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Randall Moon | grad student | 2009 | University of Washington | |
| (Chemical -genetic screening identifies novel protein regulators of Wnt /beta -catenin signaling.) | ||||
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Publications
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| Cheng J, Tsuda M, Okolotowicz K, et al. (2021) Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness. Cell Chemical Biology |
| Chien AJ, Haydu LE, Biechele TL, et al. (2014) Targeted BRAF inhibition impacts survival in melanoma patients with high levels of Wnt/β-catenin signaling. Plos One. 9: e94748 |
| Robin NC, Agoston Z, Biechele TL, et al. (2014) Simvastatin promotes adult hippocampal neurogenesis by enhancing Wnt/β-catenin signaling. Stem Cell Reports. 2: 9-17 |
| James RG, Bosch KA, Kulikauskas RM, et al. (2013) Protein kinase PKN1 represses Wnt/β-catenin signaling in human melanoma cells. The Journal of Biological Chemistry. 288: 34658-70 |
| James RG, Davidson KC, Bosch KA, et al. (2012) WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling. Plos One. 7: e50457 |
| Conrad WH, Swift RD, Biechele TL, et al. (2012) Regulating the response to targeted MEK inhibition in melanoma: enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation. Cell Cycle (Georgetown, Tex.). 11: 3724-30 |
| Davidson KC, Adams AM, Goodson JM, et al. (2012) Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4. Proceedings of the National Academy of Sciences of the United States of America. 109: 4485-90 |
| Biechele TL, Kulikauskas RM, Toroni RA, et al. (2012) Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma. Science Signaling. 5: ra3 |
| Anastas JN, Biechele TL, Robitaille M, et al. (2012) A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression. Oncogene. 31: 3696-708 |
| Biechele TL, Chien AJ, Moon RT, et al. (2012) Science Signaling Podcast: 10 January 2012 Science Signaling. 5: pc1-pc1 |