Daniel F. Tardiff, Ph.D.

Molecular and Cell Biology Brandeis University, Waltham, MA, United States 
Molecular Genetics of RNA Processing and Behavior
"Daniel Tardiff"
Mean distance: 16.72 (cluster 11)


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Michael Rosbash grad student 2007 Brandeis
 (Studies of in vivo spliceosomal and transcriptional complexes in Saccharomyces cerevisiae.)
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Khurana V, Tardiff DF, Chung CY, et al. (2015) Toward stem cell-based phenotypic screens for neurodegenerative diseases. Nature Reviews. Neurology. 11: 339-50
Tardiff DF, Khurana V, Chung CY, et al. (2014) From yeast to patient neurons and back again: powerful new discovery platform. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1231-40
Matlack KE, Tardiff DF, Narayan P, et al. (2014) Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity. Proceedings of the National Academy of Sciences of the United States of America. 111: 4013-8
Tardiff DF, Lindquist S. (2013) Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease. Drug Discovery Today. Technologies. 10: e121-8
Tardiff DF, Tucci ML, Caldwell KA, et al. (2012) Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms. The Journal of Biological Chemistry. 287: 4107-20
Ju S, Tardiff DF, Han H, et al. (2011) A yeast model of FUS/TLS-dependent cytotoxicity. Plos Biology. 9: e1001052
Su LJ, Auluck PK, Outeiro TF, et al. (2010) Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models. Disease Models & Mechanisms. 3: 194-208
Macías S, Bragulat M, Tardiff DF, et al. (2008) L30 binds the nascent RPL30 transcript to repress U2 snRNP recruitment. Molecular Cell. 30: 732-42
Tardiff DF, Abruzzi KC, Rosbash M. (2007) Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking. Proceedings of the National Academy of Sciences of the United States of America. 104: 19948-53
Tardiff DF, Lacadie SA, Rosbash M. (2006) A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional. Molecular Cell. 24: 917-29
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