Adam M. Freund, Ph.D.
Affiliations: | Molecular & Cell Biology | University of California, Berkeley, Berkeley, CA, United States |
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"Adam Freund"Parents
Sign in to add mentor| Kathleen Collins | grad student | 2010 | UC Berkeley | |
| (Signaling pathways that regulate cellular senescence.) | ||||
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Publications
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| Muñoz DP, Yannone SM, Daemen A, et al. (2019) Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging. Jci Insight. 5 |
| Freund A. (2019) Untangling Aging Using Dynamic, Organism-Level Phenotypic Networks. Cell Systems. 8: 172-181 |
| Mou H, Vinarsky V, Tata PR, et al. (2016) Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells. Cell Stem Cell |
| Wiley CD, Velarde MC, Lecot P, et al. (2015) Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype. Cell Metabolism |
| Laberge RM, Sun Y, Orjalo AV, et al. (2015) MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. Nature Cell Biology. 17: 1049-61 |
| Freund A, Zhong FL, Venteicher AS, et al. (2014) Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1. Cell. 159: 1389-403 |
| Freund A, Laberge RM, Demaria M, et al. (2012) Lamin B1 loss is a senescence-associated biomarker. Molecular Biology of the Cell. 23: 2066-75 |
| Laberge RM, Zhou L, Sarantos MR, et al. (2012) Glucocorticoids suppress selected components of the senescence-associated secretory phenotype. Aging Cell. 11: 569-78 |
| Coppé JP, Rodier F, Patil CK, et al. (2011) Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype. The Journal of Biological Chemistry. 286: 36396-403 |
| Freund A, Patil CK, Campisi J. (2011) p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype. The Embo Journal. 30: 1536-48 |