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David S. Segal

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Neuropharmacology
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"David Segal"
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Parents

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Arnold J. Mandell grad student UCSD

Children

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Peter Todd research assistant 1992-1994 UCSD
Amy F. Arnsten grad student 1976-1982 UCSD Neurosciences

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Publications

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Kuczenski R, Segal DS, Melega WP, et al. (2009) Human methamphetamine pharmacokinetics simulated in the rat: behavioral and neurochemical effects of a 72-h binge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2430-41
Clark RE, Kuczenski R, Segal DS. (2007) Escalating dose, multiple binge methamphetamine regimen does not impair recognition memory in rats. Synapse (New York, N.Y.). 61: 515-22
O'Neil ML, Kuczenski R, Segal DS, et al. (2006) Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge. Synapse (New York, N.Y.). 60: 465-73
Shilling PD, Kuczenski R, Segal DS, et al. (2006) Differential regulation of immediate-early gene expression in the prefrontal cortex of rats with a high vs low behavioral response to methamphetamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2359-67
Segal DS, Kuczenski R. (2006) Human methamphetamine pharmacokinetics simulated in the rat: single daily intravenous administration reveals elements of sensitization and tolerance. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 941-55
Segal DS, Kuczenski R, O'Neil ML, et al. (2005) Prolonged exposure of rats to intravenous methamphetamine: behavioral and neurochemical characterization. Psychopharmacology. 180: 501-12
Kuczenski R, Segal DS. (2005) Stimulant actions in rodents: implications for attention-deficit/hyperactivity disorder treatment and potential substance abuse. Biological Psychiatry. 57: 1391-6
Feifel D, Shilling PD, Kuczenski R, et al. (2003) Altered extracellular dopamine concentration in the brains of cholecystokinin-A receptor deficient rats. Neuroscience Letters. 348: 147-50
Segal DS, Kuczenski R, O'Neil ML, et al. (2003) Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1730-40
Kuczenski R, Segal DS. (2002) Exposure of adolescent rats to oral methylphenidate: preferential effects on extracellular norepinephrine and absence of sensitization and cross-sensitization to methamphetamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7264-71
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