Tristan T. Beaudette, Ph.D.

Affiliations: 
2010 Chemistry University of California, Berkeley, Berkeley, CA, United States 
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Jean M. J. Fréchet grad student 2010 UC Berkeley
 (Synthesis and Biological Evaluation of Acid-Degradable Polymeric Materials for Protein-Based Vaccines.)
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Cui L, Cohen JA, Broaders KE, et al. (2011) Mannosylated dextran nanoparticles: A pH-sensitive system engineered for immunomodulation through mannose targeting Bioconjugate Chemistry. 22: 949-957
Cohen JA, Beaudette TT, Cohen JL, et al. (2010) Acetal-modified dextran microparticles with controlled degradation kinetics and surface functionality for gene delivery in phagocytic and non-phagocytic cells Advanced Materials. 22: 3593-3597
Bachelder EM, Beaudette TT, Broaders KE, et al. (2010) In vitro analysis of acetalated dextran microparticles as a potent delivery platform for vaccine adjuvants Molecular Pharmaceutics. 7: 826-835
Ainslie KM, Lowe RD, Beaudette TT, et al. (2009) Microfabricated devices for enhanced bioadhesive drug delivery: attachment to and small-molecule release through a cell monolayer under flow. Small (Weinheim An Der Bergstrasse, Germany). 5: 2857-63
Beaudette TT, Cohen JA, Bachelder EM, et al. (2009) Chemoselective ligation in the functionalization of polysaccharide-based particles Journal of the American Chemical Society. 131: 10360-10361
Beaudette TT, Bachelder EM, Cohen JA, et al. (2009) In vivo studies on the effect of co-encapsulation of CpG DNA and antigen in acid-degradable microparticle vaccines. Molecular Pharmaceutics. 6: 1160-9
Broaders KE, Cohen JA, Beaudette TT, et al. (2009) Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 5497-502
Cohen JA, Beaudette TT, Tseng WW, et al. (2009) T-cell activation by antigen-loaded pH-sensitive hydrogel particles in vivo: the effect of particle size. Bioconjugate Chemistry. 20: 111-9
Bachelder EM, Beaudette TT, Broaders KE, et al. (2008) Acid-degradable polyurethane particles for protein-based vaccines: biological evaluation and in vitro analysis of particle degradation products. Molecular Pharmaceutics. 5: 876-84
Bachelder EM, Beaudette TT, Broaders KE, et al. (2008) Acetal-derivatized dextran: an acid-responsive biodegradable material for therapeutic applications. Journal of the American Chemical Society. 130: 10494-5
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