Paul E. O'Maille, Ph.D.

Affiliations: 
2001 Ohio State University, Columbus, Columbus, OH 
Area:
Protein Structure-Function, NMR, Enzyme Mechanism
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"Paul O'Maille"
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Parents

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Ming-Daw Tsai grad student 2001 Ohio State
 (Combinatorial protein engineering by structure -based gene shuffling.)
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Publications

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Nartey CM, Koo HJ, Laurendon C, et al. (2024) Coevolutionary Information Captures Catalytic Functions and Reveals Divergent Roles of Terpene Synthase Interdomain Connections. Biochemistry
Rebholz Z, Shewade L, Kaler K, et al. (2023) Emergence of terpene chemical communication in insects: Evolutionary recruitment of isoprenoid metabolism. Protein Science : a Publication of the Protein Society. e4634
Tholl D, Rebholz Z, Morozov AV, et al. (2023) Terpene synthases and pathways in animals: enzymology and structural evolution in the biosynthesis of volatile infochemicals. Natural Product Reports
Ballal A, Laurendon C, Salmon M, et al. (2020) Sparse epistatic patterns in the evolution of terpene synthases. Molecular Biology and Evolution
Nguyen TD, Faraldos JA, Vardakou M, et al. (2016) Discovery of germacrene A synthases in Barnadesia spinosa: The first committed step in sesquiterpene lactone biosynthesis in the basal member of the Asteraceae. Biochemical and Biophysical Research Communications
Salmon M, Thimmappa RB, Minto RE, et al. (2016) A conserved amino acid residue critical for product and substrate specificity in plant triterpene synthases. Proceedings of the National Academy of Sciences of the United States of America
Koo HJ, Vickery CR, Xu Y, et al. (2016) Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants. The Journal of Antibiotics
Salmon M, Laurendon C, Vardakou M, et al. (2015) Emergence of terpene cyclization in Artemisia annua. Nature Communications. 6: 6143
Thimmappa R, Geisler K, Louveau T, et al. (2014) Triterpene biosynthesis in plants Annual Review of Plant Biology. 65: 225-257
Crenshaw C, Aljadeff J, Fernandez I, et al. (2013) Protein Epistasis and the Biophysical Constraints on Catalytic Promiscuity Planta Medica. 79
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