Kirk D. Beebe, Ph.D.

Affiliations: 
2000 Ohio State University, Columbus, Columbus, OH 
Area:
chemical biology, medicinal chemistry
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"Kirk Beebe"
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Dehua Pei grad student 2000 Ohio State
 (Substrate recognition through modular domains: Protein tyrosine phosphatase SHP -1 and Tail -specific protease (Tsp).)
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Arabaci G, Yi T, Fu H, et al. (2002) alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship. Bioorganic & Medicinal Chemistry Letters. 12: 3047-50
Beebe KD, Wang P, Arabaci G, et al. (2000) Determination of the binding specificity of the SH2 domains of protein tyrosine phosphatase SHP-1 through the screening of a combinatorial phosphotyrosyl peptide library. Biochemistry. 39: 13251-60
Wang P, Byeon IJ, Liao H, et al. (2000) II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides. Journal of Molecular Biology. 302: 927-40
Beebe KD, Shin J, Peng J, et al. (2000) Substrate recognition through a PDZ domain in tail-specific protease. Biochemistry. 39: 3149-55
Arabaci G, Guo XC, Beebe KD, et al. (1999) α-haloacetophenone derivatives as photoreversible covalent inhibitors of protein tyrosine phosphatases Journal of the American Chemical Society. 121: 5085-5086
Beebe KD, Pei D. (1998) A continuous fluorimetric assay for tail-specific protease. Analytical Biochemistry. 263: 51-6
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