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Quyen Q. Hoang, Ph.D.

Affiliations: 
2003 McMaster University, Hamilton, ON, Canada 
 2009- Biochemistry and Molecular Biology Indiana University School of Medicine, Indianapolis, IN, United States 
Area:
Molecular modeling of protein - protein and protein - ligand interactions
Website:
https://medicine.iu.edu/departments/biochemistry-molecular-biology/faculty/20178/hoang-quyen/
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"Quyen Q. Hoang"
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Parents

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Daniel S.-C. Yang grad student 2003 McMaster University
 (Crystal structure and hydroxyapatite binding of porcine osteocalcin.)
Gregory A. Petsko post-doc 2009 Brandeis
Dagmar Ringe post-doc 2009 Brandeis
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Publications

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Fevga C, Park Y, Lohmann E, et al. (2021) A new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson's disease. Parkinsonism & Related Disorders. 89: 63-72
Wu CX, Liao J, Park Y, et al. (2019) Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics. The Journal of Biological Chemistry
O'Neil PT, Machen AJ, Thompson JA, et al. (2019) Constructing Kinetically Controlled Denaturation Isotherms of Folded Proteins Using Denaturant-Pulse Chaperonin Binding. Methods in Molecular Biology (Clifton, N.J.). 1873: 293-304
Huang X, Wu C, Park Y, et al. (2018) The Parkinson's disease-associated mutation N1437H impairs conformational dynamics in the G domain of LRRK2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802031R
Liao J, Hoang QQ. (2018) Roco Proteins and the Parkinson's Disease-Associated LRRK2. International Journal of Molecular Sciences. 19
Tashiro S, Caaveiro JMM, Nakakido M, et al. (2018) Discovery and optimization of inhibitors of the Parkinson's disease associated protein DJ-1. Acs Chemical Biology
Park Y, Hoang QQ. (2017) Combating Parkinson's disease-associated toxicity by modulating proteostasis. Proceedings of the National Academy of Sciences of the United States of America
Liu CF, Brandt GS, Hoang QQ, et al. (2016) Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites. Proceedings of the National Academy of Sciences of the United States of America. 113: E6572-E6581
Bassil F, Fernagut PO, Bezard E, et al. (2016) Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy. Proceedings of the National Academy of Sciences of the United States of America
Wang W, Nguyen LT, Burlak C, et al. (2016) Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein. Proceedings of the National Academy of Sciences of the United States of America
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