Timothy A. Vortherms, Ph.D.
Affiliations: | 2004 | Purdue University, West Lafayette, IN, United States |
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"Timothy Vortherms"Mean distance: 18.22 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Val J. Watts | grad student | 2004 | Purdue | |
| (The role of Galpha(s) in heterologous sensitization of adenylyl cyclase.) | ||||
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| Strakhova MI, Cuff CA, Manelli AM, et al. (2009) In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties. British Journal of Pharmacology. 157: 44-54 |
| Nersesian DL, Black LA, Miller TR, et al. (2008) In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series. Bioorganic & Medicinal Chemistry Letters. 18: 355-9 |
| Vortherms TA, Mosier PD, Westkaemper RB, et al. (2007) Differential helical orientations among related G protein-coupled receptors provide a novel mechanism for selectivity. Studies with salvinorin A and the kappa-opioid receptor. The Journal of Biological Chemistry. 282: 3146-56 |
| Vortherms TA, Nguyen CH, Bastepe M, et al. (2006) D2 dopamine receptor-induced sensitization of adenylyl cyclase type 1 is G alpha(s) independent. Neuropharmacology. 50: 576-84 |
| Yan F, Mosier PD, Westkaemper RB, et al. (2005) Identification of the molecular mechanisms by which the diterpenoid salvinorin A binds to kappa-opioid receptors. Biochemistry. 44: 8643-51 |
| Goldberg MS, Pisani A, Haburcak M, et al. (2005) Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron. 45: 489-96 |
| Vortherms TA, Nguyen CH, Berlot CH, et al. (2004) Using molecular tools to dissect the role of Galphas in sensitization of AC1. Molecular Pharmacology. 66: 1617-24 |
| Vortherms TA, Watts VJ. (2004) Sensitization of neuronal A2A adenosine receptors after persistent D2 dopamine receptor activation. The Journal of Pharmacology and Experimental Therapeutics. 308: 221-7 |
| Johnston CA, Cumbay MG, Vortherms TA, et al. (2001) Adrenergic agonists induce heterologous sensitization of adenylate cyclase in NS20Y-D(2L) cells. Febs Letters. 497: 85-9 |