Melissa Borgen, Ph.D.

Affiliations: 
2014 Florida Atlantic University, Boca Raton, FL, United States 
Area:
Invertebrates, competition, synapse formation
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"Melissa Borgen"
Mean distance: 15.57 (cluster 59)
 
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Parents

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Rodney K. Murphey grad student 2014 Florida Atlantic University
 (Highwire coordinates synapse formation and maturation by regulating both a map kinase cascade and the ability of the axon to respond to external cues in the giant fiber system of Drosophila melanogaster.)
Brock Grill post-doc The Scripps Research Institute, Scripps Florida
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Publications

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Amezquita J, Desbois M, Opperman KJ, et al. (2024) Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development. Plos Genetics. 20: e1011496
Borgen M, Grill B. (2024) Ubiquitin ligase signalling networks shape presynaptic development, function and disease. The Journal of Physiology
Amezquita J, Desbois M, Opperman KJ, et al. (2023) Axon development is regulated at genetic and proteomic interfaces between the integrin adhesome and the RPM-1 ubiquitin ligase signaling hub. Biorxiv : the Preprint Server For Biology
Crawley O, Opperman KJ, Desbois M, et al. (2019) Autophagy is inhibited by ubiquitin ligase activity in the nervous system. Nature Communications. 10: 5017
Borgen MA, Giles AC, Wang D, et al. (2019) Synapse maintenance is impacted by ATAT-2 tubulin acetyltransferase activity and the RPM-1 signaling hub. Elife. 8
Borgen MA, Wang D, Grill B. (2017) RPM-1 regulates axon termination by affecting growth cone collapse and microtubule stability. Development (Cambridge, England)
Borgen M, Rowland K, Boerner J, et al. (2017) Axon Termination, Pruning, and Synaptogenesis in the Giant Fiber System of Drosophila melanogaster Is Promoted by Highwire. Genetics
Grill B, Murphey RK, Borgen MA. (2016) The PHR proteins: intracellular signaling hubs in neuronal development and axon degeneration. Neural Development. 11: 8
Orr BO, Borgen MA, Caruccio PM, et al. (2014) Netrin and Frazzled regulate presynaptic gap junctions at a Drosophila giant synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5416-30
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