Brock Grill, Ph.D.

2009-2012 Pharmacology University of Minnesota, Twin Cities, Minneapolis, MN 
 2012- Neuroscience The Scripps Research Institute, Scripps Florida 
Molecular mechanisms of axon termination and synapse formation
"Brock Grill"
Mean distance: 15.62 (cluster 59)
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Crawley O, Opperman KJ, Desbois M, et al. (2019) Autophagy is inhibited by ubiquitin ligase activity in the nervous system. Nature Communications. 10: 5017
Wang D, Stoveken HM, Zucca S, et al. (2019) Genetic behavioral screen identifies an orphan anti-opioid system. Science (New York, N.Y.)
Giles AC, Desbois M, Opperman KJ, et al. (2019) A complex containing the O-GlcNAc transferase OGT-1 and the ubiquitin ligase EEL-1regulates GABA neuron function. The Journal of Biological Chemistry
Borgen MA, Giles AC, Wang D, et al. (2019) Synapse maintenance is impacted by ATAT-2 tubulin acetyltransferase activity and the RPM-1 signaling hub. Elife. 8
Desbois M, Crawley O, Evans PR, et al. (2018) PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2. The Journal of Biological Chemistry
Crawley O, Giles AC, Desbois M, et al. (2017) A MIG-15/JNK-1 MAP kinase cascade opposes RPM-1 signaling in synapse formation and learning. Plos Genetics. 13: e1007095
Borgen MA, Wang D, Grill B. (2017) RPM-1 regulates axon termination by affecting growth cone collapse and microtubule stability. Development (Cambridge, England)
Opperman KJ, Mulcahy B, Giles AC, et al. (2017) The HECT Family Ubiquitin Ligase EEL-1 Regulates Neuronal Function and Development. Cell Reports. 19: 822-835
Baker ST, Grill B. (2016) Defining minimal binding regions in Regulator of Presynaptic Morphology 1 (RPM-1) using C. elegans neurons reveals differential signaling complexes. The Journal of Biological Chemistry
Risley MG, Kelly SP, Jia K, et al. (2016) Modulating Behavior in C. elegans Using Electroshock and Antiepileptic Drugs. Plos One. 11: e0163786
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