Stephen Grossman, Ph.D.

Affiliations: 
2009 Neuroscience Brandeis University, Waltham, MA, United States 
Area:
Visual cortex
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"Stephen Grossman"
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Sacha B. Nelson grad student 2009 Brandeis
 (The dynamics of taste processing in amygdala: Studying the forebrain nature of taste perception.)
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Publications

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Parker TM, Gupta K, Palma AM, et al. (2021) Cell competition in intratumoral and tumor microenvironment interactions. The Embo Journal. e107271
Langston SP, Grossman S, England D, et al. (2021) Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry
Vaughan CA, Singh S, Subler MA, et al. (2021) The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3. Nature Communications. 12: 704
Jecrois AM, Dcona MM, Deng X, et al. (2020) Cryo-EM Structure of CtBP2 Confirms Tetrameric Architecture. Structure (London, England : 1993)
Chawla AT, Chougoni KK, Joshi PJ, et al. (2019) CtBP-a targetable dependency for tumor-initiating cell activity and metastasis in pancreatic adenocarcinoma. Oncogenesis. 8: 55
Dcona MM, Damle PK, Zarate-Perez F, et al. (2019) Active-site tryptophan, the target of anti-neoplastic CtBP inhibitors, mediates inhibitor disruption of CtBP oligomerization and transcription coregulatory activities. Molecular Pharmacology
Chawla AT, Cororaton AD, Idowu MO, et al. (2018) An intestinal stem cell niche in mutated neoplasia targetable by CtBP inhibition. Oncotarget. 9: 32408-32418
Boothello RS, Patel NJ, Damle PK, et al. (2018) Abstract 3460: p38-p14ARF-CtBP2 axis as a novel regulator of CSC phenotype and tumor cell dormancy Cancer Research. 78: 3460-3460
Dcona MM, Morris BL, Ellis KC, et al. (2017) CtBP- an emerging oncogene and novel small molecule drug target: advances in the understanding of its oncogenic action and identification of therapeutic inhibitors. Cancer Biology & Therapy. 0
Vaughan CA, Singh S, Grossman SR, et al. (2017) Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells. Molecular Oncology
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