Matthew R. Fleming, Ph.D.
Affiliations: | 2012 | Yale University, New Haven, CT |
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Parents
Sign in to add mentor| Leonard K. Kaczmarek | grad student | 2012 | Yale | |
| (Phosphorylation regulates gating and channel-protein interactions in the Slack sodium-activated potassium channel.) | ||||
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| Fleming MR, Brown MR, Kronengold J, et al. (2016) Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex. Cell Reports |
| Zhang Y, Zhang XF, Fleming MR, et al. (2016) Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating. Cell |
| Fleming MR, Shamah SM, Kaczmarek LK. (2014) Use of label-free optical biosensors to detect modulation of potassium channels by G-protein coupled receptors. Journal of Visualized Experiments : Jove. e51307 |
| Martin HC, Kim GE, Pagnamenta AT, et al. (2014) Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis. Human Molecular Genetics. 23: 3200-11 |
| Fleming MR, Kaczmarek LK. (2014) Activation of Slack Channels Alters their Interactions with the Pp1 Targeting Protein Phactr1 Biophysical Journal. 106: 543a-544a |
| Kim GE, Fleming MR, Kronengold J, et al. (2013) Biogenesis of the Sodium-Activated Potassium Channel Slack-B is Controlled by the Dephosphorylation of N-Terminal Serines Biophysical Journal. 104: 131a |
| Fleming MR, Barcia G, Colleaux L, et al. (2013) Use of Resonance-Wavelength Grating Optical Biosensors to Detect Channel-Protein Interaction in Slack KNa Channels Biophysical Journal. 104: 131a |
| Zhang Y, Brown MR, Hyland C, et al. (2012) Regulation of neuronal excitability by interaction of fragile X mental retardation protein with slack potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15318-27 |
| Barcia G, Fleming MR, Deligniere A, et al. (2012) De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy. Nature Genetics. 44: 1255-9 |
| Fleming MR, Kaczmarek LK. (2011) Phosphorylation Regulates Gating and Channel-Protein Interaction in the Slack Kna Channel Biophysical Journal. 100: 284a |