Diana W. Shineman, Ph.D.
Affiliations: | 2008 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
tau, dementia, neurodegenerationGoogle:
"Diana Shineman"Mean distance: 16.53 (cluster 24) | S | N | B | C | P |
Parents
Sign in to add mentor| Virginia Man-Yee Lee | grad student | 2008 | Penn | |
| (Signaling pathways regulating amyloid precursor protein and Abeta generation: Roles for isoprostane-induced thromboxane receptor signaling and chronic Akt activation in Alzheimer's disease.) | ||||
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Publications
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| Shineman DW, Dain AS, Kim ML, et al. (2009) Constitutively active Akt inhibits trafficking of amyloid precursor protein and amyloid precursor protein metabolites through feedback inhibition of phosphoinositide 3-kinase. Biochemistry. 48: 3787-94 |
| Cheung KH, Shineman D, Müller M, et al. (2008) Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating. Neuron. 58: 871-83 |
| Shineman DW, Zhang B, Leight SN, et al. (2008) Thromboxane receptor activation mediates isoprostane-induced increases in amyloid pathology in Tg2576 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4785-94 |
| Easton RM, Cho H, Roovers K, et al. (2005) Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Molecular and Cellular Biology. 25: 1869-78 |
| Sung S, Yang H, Uryu K, et al. (2004) Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. The American Journal of Pathology. 165: 2197-206 |