Anna Greka, Ph.D.

2004 Harvard University, Cambridge, MA, United States 
Ion channels and calcium signaling
"Anna Greka"
Mean distance: 15.54 (cluster 11)


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David E. Clapham grad student 2004 Harvard
 (TRP channels and the cytoskeleton: Implications for neuronal growth and cellular motility.)
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Ningoo M, Plant LD, Greka A, et al. (2021) PIP regulation of TRPC5 channel activation and desensitization. The Journal of Biological Chemistry. 100726
Pablo JL, Greka A. (2019) Charting a TRP to Novel Therapeutic Destinations for Kidney Diseases. Trends in Pharmacological Sciences
Dvela-Levitt M, Kost-Alimova M, Emani M, et al. (2019) Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy. Cell. 178: 521-535.e23
Sharma SH, Pablo JL, Montesinos MS, et al. (2019) Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903. Bioorganic & Medicinal Chemistry Letters. 29: 155-159
Wang L, Fu TM, Zhou Y, et al. (2018) Structures and gating mechanism of human TRPM2. Science (New York, N.Y.)
Christov M, Clark AR, Corbin B, et al. (2018) Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities. Jci Insight. 3
Sieber J, Wieder N, Clark A, et al. (2017) GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death. Cell Chemical Biology
Zhou Y, Castonguay P, Sidhom EH, et al. (2017) A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models. Science (New York, N.Y.). 358: 1332-1336
Buvall L, Wallentin H, Sieber J, et al. (2016) Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes. Journal of the American Society of Nephrology : Jasn
Zhou Y, Greka A. (2016) Calcium Signaling in the Kidney. American Journal of Physiology. Renal Physiology. ajprenal.00117.2016
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