Anna Greka, Ph.D. - Publications

Affiliations: 
2004 Harvard University, Cambridge, MA, United States 
Area:
Ion channels and calcium signaling

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ningoo M, Plant LD, Greka A, Logothetis DE. PIP regulation of TRPC5 channel activation and desensitization. The Journal of Biological Chemistry. 100726. PMID 33933453 DOI: 10.1016/j.jbc.2021.100726  0.343
2019 Pablo JL, Greka A. Charting a TRP to Novel Therapeutic Destinations for Kidney Diseases. Trends in Pharmacological Sciences. PMID 31704171 DOI: 10.1016/J.Tips.2019.10.001  0.414
2019 Dvela-Levitt M, Kost-Alimova M, Emani M, Kohnert E, Thompson R, Sidhom EH, Rivadeneira A, Sahakian N, Roignot J, Papagregoriou G, Montesinos MS, Clark AR, McKinney D, Gutierrez J, Roth M, ... ... Greka A, et al. Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy. Cell. 178: 521-535.e23. PMID 31348885 DOI: 10.1016/J.Cell.2019.07.002  0.368
2019 Sharma SH, Pablo JL, Montesinos MS, Greka A, Hopkins CR. Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903. Bioorganic & Medicinal Chemistry Letters. 29: 155-159. PMID 30538066 DOI: 10.1016/J.Bmcl.2018.12.007  0.315
2018 Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Structures and gating mechanism of human TRPM2. Science (New York, N.Y.). PMID 30467180 DOI: 10.1126/Science.Aav4809  0.413
2018 Christov M, Clark AR, Corbin B, Hakroush S, Rhee EP, Saito H, Brooks D, Hesse E, Bouxsein M, Galjart N, Jung JY, Mundel P, Jüppner H, Weins A, Greka A. Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities. Jci Insight. 3. PMID 29467330 DOI: 10.1172/Jci.Insight.95091  0.301
2017 Sieber J, Wieder N, Clark A, Reitberger M, Matan S, Schoenfelder J, Zhang J, Mandinova A, Bittker JA, Gutierrez J, Aygün O, Udeshi N, Carr S, Mundel P, Jehle AW, ... Greka A, et al. GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death. Cell Chemical Biology. PMID 29249695 DOI: 10.1016/J.Chembiol.2017.11.006  0.313
2017 Zhou Y, Castonguay P, Sidhom EH, Clark AR, Dvela-Levitt M, Kim S, Sieber J, Wieder N, Jung JY, Andreeva S, Reichardt J, Dubois F, Hoffmann SC, Basgen JM, Montesinos MS, ... ... Greka A, et al. A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models. Science (New York, N.Y.). 358: 1332-1336. PMID 29217578 DOI: 10.1126/Science.Aal4178  0.389
2016 Buvall L, Wallentin H, Sieber J, Andreeva S, Choi HY, Mundel P, Greka A. Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes. Journal of the American Society of Nephrology : Jasn. PMID 27628902 DOI: 10.1681/Asn.2016040414  0.343
2016 Zhou Y, Greka A. Calcium Signaling in the Kidney. American Journal of Physiology. Renal Physiology. ajprenal.00117.2016. PMID 27029425 DOI: 10.1152/Ajprenal.00117.2016  0.346
2016 Greka A. Human genetics of nephrotic syndrome and the quest for precision medicine. Current Opinion in Nephrology and Hypertension. PMID 26808706 DOI: 10.1097/Mnh.0000000000000204  0.361
2015 Wieder N, Greka A. Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies. Pediatric Nephrology (Berlin, Germany). PMID 26490951 DOI: 10.1007/S00467-015-3224-1  0.41
2013 Buvall L, Rashmi P, Lopez-Rivera E, Andreeva S, Weins A, Wallentin H, Greka A, Mundel P. Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics. Nature Communications. 4: 2863. PMID 24287595 DOI: 10.1038/Ncomms3863  0.326
2013 Schaldecker T, Kim S, Tarabanis C, Tian D, Hakroush S, Castonguay P, Ahn W, Wallentin H, Heid H, Hopkins CR, Lindsley CW, Riccio A, Buvall L, Weins A, Greka A. Inhibition of the TRPC5 ion channel protects the kidney filter. The Journal of Clinical Investigation. 123: 5298-309. PMID 24231357 DOI: 10.1172/Jci71165  0.409
2012 Carrasquillo R, Tian D, Krishna S, Pollak MR, Greka A, Schlöndorff J. SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity. Bmc Cell Biology. 13: 33. PMID 23171048 DOI: 10.1186/1471-2121-13-33  0.424
2012 Greka A, Mundel P. Calcium regulates podocyte actin dynamics. Seminars in Nephrology. 32: 319-26. PMID 22958486 DOI: 10.1016/J.Semnephrol.2012.06.003  0.346
2012 Greka A, Mundel P. Cell biology and pathology of podocytes. Annual Review of Physiology. 74: 299-323. PMID 22054238 DOI: 10.1146/Annurev-Physiol-020911-153238  0.364
2011 Greka A, Mundel P. Balancing calcium signals through TRPC5 and TRPC6 in podocytes. Journal of the American Society of Nephrology : Jasn. 22: 1969-80. PMID 21980113 DOI: 10.1681/Asn.2011040370  0.407
2010 Tian D, Jacobo SM, Billing D, Rozkalne A, Gage SD, Anagnostou T, Pavenstädt H, Pavenstaedt H, Hsu HH, Schlondorff J, Ramos A, Greka A. Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels. Science Signaling. 3: ra77. PMID 20978238 DOI: 10.1126/Scisignal.2001200  0.416
2007 Möller CC, Wei C, Altintas MM, Li J, Greka A, Ohse T, Pippin JW, Rastaldi MP, Wawersik S, Schiavi S, Henger A, Kretzler M, Shankland SJ, Reiser J. Induction of TRPC6 channel in acquired forms of proteinuric kidney disease. Journal of the American Society of Nephrology : Jasn. 18: 29-36. PMID 17167110 DOI: 10.1681/Asn.2006091010  0.445
2005 Moore JE, Runnels LW, Greka A, Navarro B, Clapham DE. 225 THE CALCIUM-PERMEABLE ION CHANNEL TRPM7 MAY PLAY A ROLE IN CELL MOTILITY AND WOUND REPAIR IN RAT CARDIAC FIBROBASTS Journal of Investigative Medicine. 53: S292.4-S292. DOI: 10.2310/6650.2005.00006.224  0.441
2004 Bezzerides VJ, Ramsey IS, Kotecha S, Greka A, Clapham DE. Rapid vesicular translocation and insertion of TRP channels. Nature Cell Biology. 6: 709-20. PMID 15258588 DOI: 10.1038/Ncb1150  0.686
2003 Greka A, Navarro B, Oancea E, Duggan A, Clapham DE. TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nature Neuroscience. 6: 837-45. PMID 12858178 DOI: 10.1038/Nn1092  0.666
2003 Oancea E, Bezzerides VJ, Greka A, Clapham DE. Mechanism of persistent protein kinase D1 translocation and activation. Developmental Cell. 4: 561-74. PMID 12689594 DOI: 10.1016/S1534-5807(03)00087-X  0.634
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