Erwan Bezard

Université de Bordeaux, Talence, Nouvelle-Aquitaine, France 
neurodegenerative disorders
"Erwan Bezard"

Bezard has authored or co-authored over 90 professional publications in the field of neurobiology, most of which are on Parkinson's disease and related disorders. He is perhaps best known for the reappraisal of both the identification of the nature of compensatory mechanisms that mask the progression Parkinson's disease and their sequential activation in non-human primate models that mimic Parkinson’s progression. His current research interests include the study of the compensatory mechanisms, the levodopa-induced dyskinesia, the basic pathophysiology of basal ganglia circuitry, and the development of new strategies to alleviate symptoms and/or to slow disease progression.

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Mean distance: 15.8 (cluster 6)
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Serra M, Di Maio A, Bassareo V, et al. (2023) Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration. Neurobiology of Disease. 106226
Lopez-Cuina M, Guérin P, Dutheil N, et al. (2023) GRK2-Targeted Knockdown as Therapy for Multiple System Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society
Darricau M, Katsinelos T, Raschella F, et al. (2022) Tau seeds from patients induce progressive supranuclear palsy pathology and symptoms in primates. Brain : a Journal of Neurology
Teil M, Doudnikoff E, Thiolat ML, et al. (2022) The Zinc Ionophore Clioquinol Reduces Parkinson's Disease Patient-Derived Brain Extracts-Induced Neurodegeneration. Molecular Neurobiology
Arotcarena ML, Soria FN, Cunha A, et al. (2022) Acidic nanoparticles protect against α-synuclein-induced neurodegeneration through the restoration of lysosomal function. Aging Cell. 21: e13584
Teil M, Dovero S, Bourdenx M, et al. (2022) Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology. Brain : a Journal of Neurology
Bezard E, Dehay B. (2022) [Aggregation and spread of synuclein in Parkinson's disease]. Medecine Sciences : M/S. 38: 45-51
Laferrière F, Claverol S, Bezard E, et al. (2022) Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson's disease. Npj Parkinson's Disease. 8: 10
Novello S, Mercatelli D, Albanese F, et al. (2022) In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity. Neurobiology of Disease. 162: 105579
Blesa J, Foffani G, Dehay B, et al. (2021) Motor and non-motor circuit disturbances in early Parkinson disease: which happens first? Nature Reviews. Neuroscience
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