| Year |
Citation |
Score |
| 2024 |
Sikora J, Dovero S, Kinet R, Arotcarena ML, Bohic S, Bezard E, Fernagut PO, Dehay B. Nigral ATP13A2 depletion induces Parkinson's disease-related neurodegeneration in a pilot study in non-human primates. Npj Parkinson's Disease. 10: 141. PMID 39090150 DOI: 10.1038/s41531-024-00757-4 |
0.833 |
|
| 2024 |
Bezard E, Teil M, Arotcarena ML, Porras G, Li Q, Dehay B. Corrigendum: Modeling Parkinson's Disease in Primates. Cold Spring Harbor Perspectives in Medicine. PMID 39054071 DOI: 10.1101/cshperspect.a041802 |
0.651 |
|
| 2024 |
Bezard E, Teil M, Arotcarena ML, Porras G, Li Q, Dehay B. Modeling Parkinson's Disease in Primates. Cold Spring Harbor Perspectives in Medicine. PMID 38858083 DOI: 10.1101/cshperspect.a041612 |
0.689 |
|
| 2024 |
Cirillo R, Duperrier S, Parekh P, Millot M, Li Q, Thiolat ML, Morelli M, Xie J, Le Bars D, Redouté J, Bezard E, Sgambato V. Striatal Serotonin 4 Receptor is Increased in Experimental Parkinsonism and Dyskinesia. Journal of Parkinson's Disease. PMID 38339940 DOI: 10.3233/JPD-230331 |
0.372 |
|
| 2023 |
Rocha E, Chamoli M, Chinta SJ, Andersen JK, Wallis R, Bezard E, Goldberg M, Greenamyre T, Hirst W, Kuan WL, Kirik D, Niedernhofer L, Rappley I, Padmanabhan S, Trudeau LE, et al. Aging, Parkinson's Disease, and Models: What Are the Challenges? Aging Biology. 1. PMID 38978807 DOI: 10.59368/agingbio.20230010 |
0.317 |
|
| 2023 |
Darricau M, Dou C, Kinet R, Zhu T, Zhou L, Li X, Bedel A, Claverol S, Tokarski C, Katsinelos T, McEwan WA, Zhang L, Gao R, Bourdenx M, Dehay B, ... ... Bezard E, et al. Tau seeds from Alzheimer's disease brains trigger tau spread in macaques while oligomeric-Aβ mediates pathology maturation. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38148705 DOI: 10.1002/alz.13604 |
0.752 |
|
| 2023 |
Teil M, Dovero S, Bourdenx M, Arotcarena ML, Darricau M, Porras G, Thiolat ML, Trigo-Damas I, Perier C, Estrada C, Garcia-Carrillo N, Herrero MT, Vila M, Obeso JA, Bezard E, et al. Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain. Npj Parkinson's Disease. 9: 135. PMID 37726343 DOI: 10.1038/s41531-023-00579-w |
0.835 |
|
| 2023 |
Serra M, Di Maio A, Bassareo V, Nuzzo T, Errico F, Servillo F, Capasso M, Parekh P, Li Q, Thiolat ML, Bezard E, Calabresi P, Sulzer D, Carta M, Morelli M, et al. Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration. Neurobiology of Disease. 106226. PMID 37451474 DOI: 10.1016/j.nbd.2023.106226 |
0.36 |
|
| 2023 |
Lopez-Cuina M, Guérin P, Dutheil N, Martin C, Lasserre TL, Fernagut PO, Meissner WG, Bezard E. GRK2-Targeted Knockdown as Therapy for Multiple System Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 37093618 DOI: 10.1002/mds.29422 |
0.572 |
|
| 2022 |
Darricau M, Katsinelos T, Raschella F, Milekovic T, Crochemore L, Li Q, Courtine G, McEwan WA, Dehay B, Bezard E, Planche V. Tau seeds from patients induce progressive supranuclear palsy pathology and symptoms in primates. Brain : a Journal of Neurology. PMID 36382344 DOI: 10.1093/brain/awac428 |
0.64 |
|
| 2022 |
Teil M, Doudnikoff E, Thiolat ML, Bohic S, Bezard E, Dehay B. The Zinc Ionophore Clioquinol Reduces Parkinson's Disease Patient-Derived Brain Extracts-Induced Neurodegeneration. Molecular Neurobiology. PMID 35915387 DOI: 10.1007/s12035-022-02974-5 |
0.669 |
|
| 2022 |
Arotcarena ML, Soria FN, Cunha A, Doudnikoff E, Prévot G, Daniel J, Blanchard-Desce M, Barthélémy P, Bezard E, Crauste-Manciet S, Dehay B. Acidic nanoparticles protect against α-synuclein-induced neurodegeneration through the restoration of lysosomal function. Aging Cell. 21: e13584. PMID 35318803 DOI: 10.1111/acel.13584 |
0.673 |
|
| 2022 |
Teil M, Dovero S, Bourdenx M, Arotcarena ML, Camus S, Porras G, Thiolat ML, Trigo-Damas I, Perier C, Estrada C, Garcia-Carrillo N, Morari M, Meissner WG, Herrero MT, Vila M, ... ... Bezard E, et al. Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology. Brain : a Journal of Neurology. PMID 35285474 DOI: 10.1093/brain/awab374 |
0.833 |
|
| 2022 |
Bezard E, Dehay B. [Aggregation and spread of synuclein in Parkinson's disease]. Medecine Sciences : M/S. 38: 45-51. PMID 35060886 DOI: 10.1051/medsci/2021241 |
0.661 |
|
| 2022 |
Laferrière F, Claverol S, Bezard E, De Giorgi F, Ichas F. Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson's disease. Npj Parkinson's Disease. 8: 10. PMID 35027576 DOI: 10.1038/s41531-021-00264-w |
0.313 |
|
| 2022 |
Novello S, Mercatelli D, Albanese F, Domenicale C, Brugnoli A, D'Aversa E, Vantaggiato S, Dovero S, Murtaj V, Presotto L, Borgatti M, Shimshek DR, Bezard E, Moresco RM, Belloli S, et al. In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity. Neurobiology of Disease. 162: 105579. PMID 34871735 DOI: 10.1016/j.nbd.2021.105579 |
0.798 |
|
| 2021 |
Blesa J, Foffani G, Dehay B, Bezard E, Obeso JA. Motor and non-motor circuit disturbances in early Parkinson disease: which happens first? Nature Reviews. Neuroscience. PMID 34907352 DOI: 10.1038/s41583-021-00542-9 |
0.665 |
|
| 2021 |
Arotcarena ML, Dovero S, Biendon N, Dutheil N, Planche V, Bezard E, Dehay B. Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques. Frontiers in Bioengineering and Biotechnology. 9: 762209. PMID 34869273 DOI: 10.3389/fbioe.2021.762209 |
0.757 |
|
| 2021 |
Malave L, Zuelke DR, Uribe-Cano S, Starikov L, Rebholz H, Friedman E, Qin C, Li Q, Bezard E, Kottmann AH. Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson's disease and L-Dopa induced dyskinesia. Communications Biology. 4: 1071. PMID 34552196 DOI: 10.1038/s42003-021-02567-3 |
0.426 |
|
| 2021 |
Bassil F, Delamarre A, Canron MH, Dutheil N, Vital A, Négrier-Leibreich ML, Bezard E, Fernagut PO, Meissner WG. Impaired brain insulin signalling in Parkinson's disease. Neuropathology and Applied Neurobiology. PMID 34405431 DOI: 10.1111/nan.12760 |
0.63 |
|
| 2021 |
Darricau M, Canron MH, Bosc M, Arotçarena ML, Quang ML, Dehay B, Bezard E, Planche V. Lack of limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes in aged macaques with memory impairment. Neurobiology of Aging. 107: 53-56. PMID 34384992 DOI: 10.1016/j.neurobiolaging.2021.07.009 |
0.55 |
|
| 2021 |
Sun X, Yu X, Zhang L, Zhao W, Wang M, Zhang Y, Li X, Gao R, Breger LS, Dovero S, Porras G, Fernagut PO, Dehay B, Bezard E, Qin C. Comparison of the expression and toxicity of AAV2/9 carrying the human A53T α-synuclein gene in presence or absence of WPRE. Heliyon. 7: e06302. PMID 33665452 DOI: 10.1016/j.heliyon.2021.e06302 |
0.805 |
|
| 2021 |
Fridjonsdottir E, Shariatgorji R, Nilsson A, Vallianatou T, Odell LR, Schembri LS, Svenningsson P, Fernagut PO, Crossman AR, Bezard E, Andrén PE. Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA-induced dyskinesia. Science Advances. 7. PMID 33523980 DOI: 10.1126/sciadv.abe5948 |
0.796 |
|
| 2021 |
Feyder M, Plewnia C, Lieberman OJ, Spigolon G, Piccin A, Urbina L, Dehay B, Li Q, Nilsson P, Altun M, Santini E, Sulzer D, Bezard E, Borgkvist A, Fisone G. Involvement of Autophagy in Levodopa-Induced Dyskinesia. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33460487 DOI: 10.1002/mds.28480 |
0.653 |
|
| 2021 |
Yu X, Persillet M, Zhang L, Zhang Y, Xiuping S, Li X, Ran G, Breger LS, Dovero S, Porras G, Dehay B, Bezard E, Qin C. Evaluation of blood flow as a route for propagation in experimental synucleinopathy. Neurobiology of Disease. 105255. PMID 33421564 DOI: 10.1016/j.nbd.2021.105255 |
0.784 |
|
| 2020 |
Deffains M, Canron MH, Teil M, Li Q, Dehay B, Bezard E, Fernagut PO. L-DOPA regulates α-synuclein accumulation in experimental parkinsonism. Neuropathology and Applied Neurobiology. PMID 33275784 DOI: 10.1111/nan.12678 |
0.781 |
|
| 2020 |
Marmion DJ, Rutkowski AA, Chatterjee D, Hiller BM, Werner MH, Bezard E, Kirik D, McCown T, Gray SJ, Kordower JH. Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease. Neurobiology of Disease. 105184. PMID 33221532 DOI: 10.1016/j.nbd.2020.105184 |
0.325 |
|
| 2020 |
Outeiro TF, Heutink P, Bezard E, Cenci AM. From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33200446 DOI: 10.1002/mds.28387 |
0.351 |
|
| 2020 |
Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV, Siddique I, Li Z, Vingill S, Cioroch M, Cavaliere F, Threlfell S, Roberts B, Schrader T, Klärner FG, ... ... Bezard E, et al. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nature Communications. 11: 4885. PMID 32985503 DOI: 10.1038/s41467-020-18689-x |
0.664 |
|
| 2020 |
Bezard E, Li Q, Hulme H, Fridjonsdottir E, Nilsson A, Pioli E, Andren PE, Crossman AR. µ opioid receptor agonism for L-DOPA-induced dyskinesia in Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32690616 DOI: 10.1523/JNEUROSCI.0610-20.2020 |
0.731 |
|
| 2020 |
Soria FN, Paviolo C, Doudnikoff E, Arotcarena ML, Lee A, Danné N, Mandal AK, Gosset P, Dehay B, Groc L, Cognet L, Bezard E. Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling. Nature Communications. 11: 3440. PMID 32651387 DOI: 10.1038/S41467-020-17328-9 |
0.631 |
|
| 2020 |
Maxan A, Sciacca G, Alpaugh M, Tao Z, Breger L, Dehay B, Ling Z, Qin C, Cisbani G, Masnata M, Salem S, Lacroix S, Oueslati A, Bezard E, Cicchetti F. Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates. Neurobiology of Disease. 104951. PMID 32439599 DOI: 10.1016/J.Nbd.2020.104951 |
0.631 |
|
| 2020 |
Bourdenx M, Nioche A, Dovero S, Arotcarena ML, Camus S, Porras G, Thiolat ML, Rougier NP, Prigent A, Aubert P, Bohic S, Sandt C, Laferrière F, Doudnikoff E, Kruse N, ... ... Bezard E, et al. Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates. Science Advances. 6: eaaz9165. PMID 32426502 DOI: 10.1126/Sciadv.Aaz9165 |
0.82 |
|
| 2020 |
Eshraghi M, Ramírez-Jarquín UN, Shahani N, Nuzzo T, De Rosa A, Swarnkar S, Galli N, Rivera O, Tsaprailis G, Scharager-Tapia C, Crynen G, Li Q, Thiolat ML, Bezard E, Usiello A, et al. RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease. Science Advances. 6: eaaz7001. PMID 32426479 DOI: 10.1126/sciadv.aaz7001 |
0.436 |
|
| 2020 |
Gosset P, Maxan A, Alpaugh M, Breger L, Dehay B, Tao Z, Ling Z, Qin C, Cisbani G, Fortin N, Vonsattel JG, Lacroix S, Oueslati A, Bezard E, Cicchetti F. Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates. Neurobiology of Disease. 104941. PMID 32422281 DOI: 10.1016/J.Nbd.2020.104941 |
0.653 |
|
| 2020 |
Arotcarena ML, Dovero S, Prigent A, Bourdenx M, Camus S, Porras G, Thiolat ML, Tasselli M, Aubert P, Kruse N, Mollenhauer B, Damas IT, Estrada C, Garcia-Carrillo N, Vaikath NN, ... ... Bezard E, et al. Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates. Brain : a Journal of Neurology. PMID 32380543 DOI: 10.1093/Brain/Awaa096 |
0.828 |
|
| 2020 |
Deffains M, Haï Nguyen T, Orignac H, Biendon N, Dovero S, Bezard E, Boraud T. In vivo electrophysiological validation of DREADD-based modulation of pallidal neurons in the non-human primate. The European Journal of Neuroscience. PMID 32306446 DOI: 10.1111/Ejn.14746 |
0.78 |
|
| 2020 |
Lopez-Cuina M, Guerin PA, Canron MH, Delamarre A, Dehay B, Bezard E, Meissner WG, Fernagut PO. Nilotinib Fails to Prevent Synucleinopathy and Cell Loss in a Mouse Model of Multiple System Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32291831 DOI: 10.1002/Mds.28034 |
0.784 |
|
| 2020 |
Moreau C, Rolland AS, Pioli E, Li Q, Odou P, Barthelemy C, Lannoy D, Demailly A, Carta N, Deramecourt V, Auger F, Kuchcinski G, Laloux C, Defebvre L, Bordet R, ... ... Bezard E, et al. Intraventricular dopamine infusion alleviates motor symptoms in a primate model of Parkinson's disease. Neurobiology of Disease. 104846. PMID 32205254 DOI: 10.1016/j.nbd.2020.104846 |
0.476 |
|
| 2020 |
Teil M, Arotcarena ML, Faggiani E, Laferriere F, Bezard E, Dehay B. Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts. Biomolecules. 10. PMID 32138193 DOI: 10.3390/biom10030391 |
0.657 |
|
| 2020 |
Faivre F, Sánchez-Catalán MJ, Dovero S, Bido S, Joshi A, Bezard E, Barrot M. Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease. Neurobiology of Disease. 104818. PMID 32087289 DOI: 10.1016/j.nbd.2020.104818 |
0.737 |
|
| 2020 |
Ribot B, Aupy J, Vidailhet M, Mazère J, Pisani A, Bezard E, Guehl D, Burbaud P. Corrigendum to "Dystonia and dopamine: From phenomenology to pathophysiology" [Prog. Neurobiol. 182 (November) (2019), 101678, 18]. Progress in Neurobiology. 101745. PMID 31928793 DOI: 10.1016/J.Pneurobio.2019.101745 |
0.608 |
|
| 2020 |
Hulme H, Fridjonsdottir E, Gunnarsdottir H, Vallianatou T, Zhang X, Wadensten H, Shariatgorji R, Nilsson A, Bezard E, Svenningsson P, Andrén PE. Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy. Neurobiology of Disease. 104738. PMID 31927144 DOI: 10.1016/j.nbd.2020.104738 |
0.423 |
|
| 2020 |
Bertin E, Deluc T, Pilch KS, Martinez A, Pougnet JT, Doudnikoff E, Allain AE, Bergmann P, Russeau M, Toulmé E, Bezard E, Koch-Nolte F, Séguéla P, Lévi S, Bontempi B, et al. Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice. Molecular Psychiatry. PMID 31911635 DOI: 10.1038/s41380-019-0641-8 |
0.326 |
|
| 2019 |
Bezard E. Models of hyperkinetic disorders in primates. Journal of Neuroscience Methods. 332: 108551. PMID 31857131 DOI: 10.1016/j.jneumeth.2019.108551 |
0.35 |
|
| 2019 |
Meissner WG, Fernagut PO, Dehay B, Péran P, Traon AP, Foubert-Samier A, Lopez Cuina M, Bezard E, Tison F, Rascol O. Multiple System Atrophy: Recent Developments and Future Perspectives. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31692132 DOI: 10.1002/Mds.27894 |
0.78 |
|
| 2019 |
Dehay B, Bezard E. Intrastriatal injection of alpha-synuclein fibrils induces Parkinson-like pathology in macaques. Brain : a Journal of Neurology. 142: 3321-3322. PMID 31665750 DOI: 10.1093/Brain/Awz329 |
0.643 |
|
| 2019 |
Mercatelli D, Bezard E, Eleopra R, Zaveri NT, Morari M. Managing Parkinson's disease: Moving ON with NOP. British Journal of Pharmacology. PMID 31648371 DOI: 10.1111/Bph.14893 |
0.628 |
|
| 2019 |
Arotcarena ML, Bourdenx M, Dutheil N, Thiolat ML, Doudnikoff E, Dovero S, Ballabio A, Fernagut PO, Meissner WG, Bezard E, Dehay B. Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies. Jci Insight. 4. PMID 31434803 DOI: 10.1172/Jci.Insight.129719 |
0.827 |
|
| 2019 |
Ribot B, Aupy J, Vidailhet M, Mazère J, Pisani A, Bezard E, Guehl D, Burbaud P. Dystonia and dopamine: From phenomenology to pathophysiology. Progress in Neurobiology. 101678. PMID 31404592 DOI: 10.1016/J.Pneurobio.2019.101678 |
0.632 |
|
| 2019 |
Rosenblad C, Li Q, Pioli EY, Dovero S, Antunes ASLM, Agúndez L, Bardelli M, Linden RM, Henckaerts E, Björklund A, Bezard E, Björklund T. Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease. Brain : a Journal of Neurology. PMID 31243443 DOI: 10.1093/Brain/Awz176 |
0.74 |
|
| 2019 |
Nuzzo T, Punzo D, Devoto P, Rosini E, Paciotti S, Sacchi S, Li Q, Thiolat ML, Véga C, Carella M, Carta M, Gardoni F, Calabresi P, Pollegioni L, Bezard E, et al. The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson's disease patients. Scientific Reports. 9: 8898. PMID 31222058 DOI: 10.1038/S41598-019-45419-1 |
0.427 |
|
| 2019 |
Delamarre A, Tison F, Li Q, Galitzky M, Rascol O, Bezard E, Meissner WG. Assessment of plasma creatine kinase as biomarker for levodopa-induced dyskinesia in Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 31098725 DOI: 10.1007/s00702-019-02015-x |
0.358 |
|
| 2019 |
Li Q, Fernagut PO, Bezard E. l-Dopa-free learned dyskinetic behavior in a Parkinson's primate model. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31083822 DOI: 10.1002/Mds.27715 |
0.655 |
|
| 2019 |
Thomasson N, Pioli E, Friedel C, Monseur A, Lavaur J, Moya KL, Bezard E, Bousseau A, Prochiantz A. Engrailed-1 induces long-lasting behavior benefit in an experimental Parkinson primate model. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31077447 DOI: 10.1002/Mds.27714 |
0.337 |
|
| 2019 |
Goubault E, Nguyen HP, Bogard S, Blanchet PJ, Bézard E, Vincent C, Sarna J, Monchi O, Duval C. Remnants of Cardinal Symptoms of Parkinson's Disease, Not Dyskinesia, Are Problematic for Dyskinetic Patients Performing Activities of Daily Living. Frontiers in Neurology. 10: 256. PMID 30967832 DOI: 10.3389/Fneur.2019.00256 |
0.374 |
|
| 2019 |
Laferrière F, Maniecka Z, Pérez-Berlanga M, Hruska-Plochan M, Gilhespy L, Hock EM, Wagner U, Afroz T, Boersema PJ, Barmettler G, Foti SC, Asi YT, Isaacs AM, Al-Amoudi A, Lewis A, ... ... Bezard E, et al. TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates. Nature Neuroscience. 22: 65-77. PMID 30559480 DOI: 10.1038/S41593-018-0294-Y |
0.366 |
|
| 2018 |
Bonsi P, Ponterio G, Vanni V, Tassone A, Sciamanna G, Migliarini S, Martella G, Meringolo M, Dehay B, Doudnikoff E, Zachariou V, Goodchild RE, Mercuri NB, D'Amelio M, Pasqualetti M, ... Bezard E, et al. RGS9-2 rescues dopamine D2 receptor levels and signaling in dystonia mouse models. Embo Molecular Medicine. PMID 30552094 DOI: 10.15252/Emmm.201809283 |
0.651 |
|
| 2018 |
Prevot G, Soria FN, Thiolat ML, Daniel J, Verlhac JB, Blanchard-Desce M, Bezard E, Barthelemy P, Crauste-Manciet S, Dehay B. Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-related Neurodegenerative Diseases. Bioconjugate Chemistry. PMID 30424597 DOI: 10.1021/Acs.Bioconjchem.8B00697 |
0.649 |
|
| 2018 |
Faivre F, Joshi A, Bezard E, Barrot M. The hidden side of Parkinson's disease: studying pain, anxiety and depression in animal models. Neuroscience and Biobehavioral Reviews. PMID 30365972 DOI: 10.1016/j.neubiorev.2018.10.004 |
0.399 |
|
| 2018 |
Espay AJ, Morgante F, Merola A, Fasano A, Marsili L, Fox SH, Bezard E, Picconi B, Calabresi P, Lang AE. Levodopa-induced dyskinesia in Parkinson disease: Current and Evolving Concepts. Annals of Neurology. PMID 30357892 DOI: 10.1002/ana.25364 |
0.463 |
|
| 2018 |
Mellone M, Zianni E, Stanic J, Campanelli F, Marino G, Ghiglieri V, Longhi A, Thiolat ML, Li Q, Calabresi P, Bezard E, Picconi B, Di Luca M, Gardoni F. NMDA receptor GluN2D subunit participates to levodopa-induced dyskinesia pathophysiology. Neurobiology of Disease. PMID 30261285 DOI: 10.1016/j.nbd.2018.09.021 |
0.486 |
|
| 2018 |
Charvin D, Di Paolo T, Bezard E, Gregoire L, Takano A, Duvey G, Pioli E, Halldin C, Medori R, Conquet F. An mGlu4-Positive Allosteric Modulator Alleviates Parkinsonism in Primates. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 30216534 DOI: 10.1002/Mds.27462 |
0.446 |
|
| 2018 |
Novello S, Arcuri L, Dovero S, Dutheil N, Shimshek DR, Bezard E, Morari M. G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice. Neurobiology of Disease. PMID 30172844 DOI: 10.1016/J.Nbd.2018.08.018 |
0.821 |
|
| 2018 |
Boland B, Yu WH, Corti O, Mollereau B, Henriques A, Bezard E, Pastores GM, Rubinsztein DC, Nixon RA, Duchen MR, Mallucci GR, Kroemer G, Levine B, Eskelinen EL, Mochel F, et al. Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing. Nature Reviews. Drug Discovery. PMID 30116051 DOI: 10.1038/Nrd.2018.109 |
0.357 |
|
| 2018 |
Chansel-Debordeaux L, Bourdenx M, Dutheil N, Dovero S, Canron MH, Jimenez C, Bezard E, Dehay B. Systemic gene delivery by single-dose intracardiac administration of scAAV2/9 and scAAV2/rh10 variants in newborn rats. Human Gene Therapy Methods. PMID 30064266 DOI: 10.1089/Hgtb.2017.192.R3 |
0.782 |
|
| 2018 |
Rojo-Bustamante E, Abellanas MA, Clavero P, Thiolat ML, Li Q, Luquin MR, Bezard E, Aymerich MS. The expression of cannabinoid type 1 receptor and 2-arachidonoyl glycerol synthesizing/degrading enzymes is altered in basal ganglia during the active phase of levodopa-induced dyskinesia. Neurobiology of Disease. PMID 29936234 DOI: 10.1016/j.nbd.2018.06.019 |
0.383 |
|
| 2018 |
Goubault E, Nguyen HP, Bogard S, Blanchet PJ, Bézard E, Vincent C, Langlois M, Duval C. Cardinal Motor Features of Parkinson's Disease Coexist with Peak-Dose Choreic-Type Drug-Induced Dyskinesia: Parkinson's Symptoms Coexist with Dyskinesia. Journal of Parkinson's Disease. PMID 29843253 DOI: 10.3233/Jpd-181312 |
0.432 |
|
| 2018 |
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| 2013 |
Bézard E, Muñoz A, Tronci E, Pioli EY, Li Q, Porras G, Björklund A, Carta M. Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia. Neuroscience Research. 77: 242-6. PMID 24135129 DOI: 10.1016/J.Neures.2013.10.002 |
0.495 |
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| 2013 |
Dupuis JP, Feyder M, Miguelez C, Garcia L, Morin S, Choquet D, Hosy E, Bezard E, Fisone G, Bioulac BH, Baufreton J. Dopamine-dependent long-term depression at subthalamo-nigral synapses is lost in experimental parkinsonism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14331-41. PMID 24005286 DOI: 10.1523/Jneurosci.1681-13.2013 |
0.736 |
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| 2013 |
Dehay B, Martinez-Vicente M, Caldwell GA, Caldwell KA, Yue Z, Cookson MR, Klein C, Vila M, Bezard E. Lysosomal impairment in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 725-32. PMID 23580333 DOI: 10.1002/Mds.25462 |
0.743 |
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| 2013 |
Engeln M, Fasano S, Ahmed SH, Cador M, Baekelandt V, Bezard E, Fernagut PO. Levodopa gains psychostimulant-like properties after nigral dopaminergic loss. Annals of Neurology. 74: 140-4. PMID 23494678 DOI: 10.1002/Ana.23881 |
0.834 |
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| 2013 |
Bezard E, Tronci E, Pioli EY, Li Q, Porras G, Björklund A, Carta M. Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 1088-96. PMID 23389842 DOI: 10.1002/Mds.25366 |
0.438 |
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| 2013 |
Tison F, Nègre-Pagès L, Meissner WG, Dupouy S, Li Q, Thiolat ML, Thiollier T, Galitzky M, Ory-Magne F, Milhet A, Marquine L, Spampinato U, Rascol O, Bezard E. Simvastatin decreases levodopa-induced dyskinesia in monkeys, but not in a randomized, placebo-controlled, multiple cross-over ("n-of-1") exploratory trial of simvastatin against levodopa-induced dyskinesia in Parkinson's disease patients. Parkinsonism & Related Disorders. 19: 416-21. PMID 23283428 DOI: 10.1016/j.parkreldis.2012.12.003 |
0.356 |
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| 2013 |
Schneider JS, Pioli EY, Jianzhong Y, Li Q, Bezard E. Levodopa improves motor deficits but can further disrupt cognition in a macaque Parkinson model. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 663-7. PMID 23238827 DOI: 10.1002/mds.25258 |
0.371 |
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| 2013 |
Bezard E. Experimental reappraisal of continuous dopaminergic stimulation against L-dopa-induced dyskinesia. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 1021-2. PMID 23143999 DOI: 10.1002/mds.25251 |
0.456 |
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| 2013 |
Engeln M, Ahmed SH, Vouillac C, Tison F, Bezard E, Fernagut PO. Reinforcing properties of Pramipexole in normal and parkinsonian rats. Neurobiology of Disease. 49: 79-86. PMID 22940424 DOI: 10.1016/J.Nbd.2012.08.005 |
0.81 |
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| 2013 |
Bezard E, Yue Z, Kirik D, Spillantini MG. Animal models of Parkinson's disease: limits and relevance to neuroprotection studies. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 61-70. PMID 22753348 DOI: 10.1002/Mds.25108 |
0.459 |
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| 2012 |
Tass PA, Qin L, Hauptmann C, Dovero S, Bezard E, Boraud T, Meissner WG. Coordinated reset has sustained aftereffects in Parkinsonian monkeys. Annals of Neurology. 72: 816-20. PMID 23280797 DOI: 10.1002/ana.23663 |
0.8 |
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| 2012 |
Marti M, Rodi D, Li Q, Guerrini R, Fasano S, Morella I, Tozzi A, Brambilla R, Calabresi P, Simonato M, Bezard E, Morari M. Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16106-19. PMID 23152595 DOI: 10.1523/Jneurosci.6408-11.2012 |
0.549 |
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| 2012 |
Porras G, Berthet A, Dehay B, Li Q, Ladepeche L, Normand E, Dovero S, Martinez A, Doudnikoff E, Martin-Négrier ML, Chuan Q, Bloch B, Choquet D, Boué-Grabot E, Groc L, ... Bezard E, et al. PSD-95 expression controls L-DOPA dyskinesia through dopamine D1 receptor trafficking. The Journal of Clinical Investigation. 122: 3977-89. PMID 23041629 DOI: 10.1172/Jci59426 |
0.803 |
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| 2012 |
Fox SH, Johnston TH, Li Q, Brotchie J, Bezard E. A critique of available scales and presentation of the Non-Human Primate Dyskinesia Rating Scale. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1373-8. PMID 22976821 DOI: 10.1002/mds.25133 |
0.705 |
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| 2012 |
Miguelez C, Morin S, Martinez A, Goillandeau M, Bezard E, Bioulac B, Baufreton J. Altered pallido-pallidal synaptic transmission leads to aberrant firing of globus pallidus neurons in a rat model of Parkinson's disease. The Journal of Physiology. 590: 5861-75. PMID 22890706 DOI: 10.1113/jphysiol.2012.241331 |
0.692 |
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| 2012 |
Dehay B, Martinez-Vicente M, Ramirez A, Perier C, Klein C, Vila M, Bezard E. Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove. Autophagy. 8: 1389-91. PMID 22885599 DOI: 10.4161/Auto.21011 |
0.687 |
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| 2012 |
Dehay B, Ramirez A, Martinez-Vicente M, Perier C, Canron MH, Doudnikoff E, Vital A, Vila M, Klein C, Bezard E. Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 109: 9611-6. PMID 22647602 DOI: 10.1073/Pnas.1112368109 |
0.695 |
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| 2012 |
Porras G, Li Q, Bezard E. Modeling Parkinson's disease in primates: The MPTP model. Cold Spring Harbor Perspectives in Medicine. 2: a009308. PMID 22393538 DOI: 10.1101/cshperspect.a009308 |
0.417 |
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| 2012 |
Dehay B, Dalkara D, Dovero S, Li Q, Bezard E. Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques. Scientific Reports. 2: 253. PMID 22355765 DOI: 10.1038/Srep00253 |
0.771 |
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| 2012 |
Berthet A, Bezard E, Porras G, Fasano S, Barroso-Chinea P, Dehay B, Martinez A, Thiolat ML, Nosten-Bertrand M, Giros B, Baufreton J, Li Q, Bloch B, Martin-Negrier ML. L-DOPA impairs proteasome activity in parkinsonism through D1 dopamine receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 681-91. PMID 22238104 DOI: 10.1523/Jneurosci.1541-11.2012 |
0.714 |
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| 2012 |
Keywood C, Bezard E, Hill M, Li Q, Girard F, Poli S, Mutel V. 2.231 ADX48621, A MGLUR5 NEGATIVE ALLOSTERIC MODULATOR ALLEVIATES L-DOPA-INDUCED CHOREA AND DYSTONIA IN THE MPTP MACAQUE MODEL OF PARKINSON'S DISEASE Parkinsonism & Related Disorders. 18: S122. DOI: 10.1016/S1353-8020(11)70555-7 |
0.439 |
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| 2012 |
Bezard E, Pisani A, Berton O. Neuroscience disease models Neuroscience. 211: 1. DOI: 10.1016/j.neuroscience.2012.04.022 |
0.327 |
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| 2012 |
Bezard E. Animal models of Parkinson's disease Neurophysiologie Clinique/Clinical Neurophysiology. 42: 77. DOI: 10.1016/j.neucli.2011.11.019 |
0.42 |
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| 2011 |
Tass PA, Qin L, Hauptmann C, Dovero S, Bezard E, Boraud T, Meissner WG. The translational value of the MPTP non-human primate model of Parkinsonism for deep brain stimulation research. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 663-6. PMID 22254396 DOI: 10.1109/IEMBS.2011.6090148 |
0.791 |
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| 2011 |
Dehay B, Bezard E. New animal models of Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1198-1205. PMID 22046592 DOI: 10.1002/Mds.23546 |
0.706 |
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| 2011 |
Fisone G, Bezard E. Molecular mechanisms of l-DOPA-induced dyskinesia. International Review of Neurobiology. 98: 95-122. PMID 21907084 DOI: 10.1016/B978-0-12-381328-2.00004-3 |
0.463 |
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| 2011 |
Gonon F, Bezard E, Boraud T. What should be said to the lay public regarding ADHD etiology. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 989-91. PMID 21882340 DOI: 10.1002/Ajmg.B.31236 |
0.546 |
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| 2011 |
Carta M, Bezard E. Contribution of pre-synaptic mechanisms to L-DOPA-induced dyskinesia. Neuroscience. 198: 245-51. PMID 21840375 DOI: 10.1016/J.Neuroscience.2011.07.070 |
0.418 |
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| 2011 |
Charron G, Doudnikoff E, Laux A, Berthet A, Porras G, Canron MH, Barroso-Chinea P, Li Q, Qin C, Nosten-Bertrand M, Giros B, Delalande F, Van Dorsselaer A, Vital A, Goumon Y, ... Bezard E, et al. Endogenous morphine-like compound immunoreactivity increases in parkinsonism. Brain : a Journal of Neurology. 134: 2321-38. PMID 21742735 DOI: 10.1093/Brain/Awr166 |
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| 2011 |
Bezard E, Przedborski S. A tale on animal models of Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 993-1002. PMID 21626544 DOI: 10.1002/Mds.23696 |
0.643 |
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| 2011 |
Meissner WG, Frasier M, Gasser T, Goetz CG, Lozano A, Piccini P, Obeso JA, Rascol O, Schapira A, Voon V, Weiner DM, Tison F, Bezard E. Priorities in Parkinson's disease research. Nature Reviews. Drug Discovery. 10: 377-93. PMID 21532567 DOI: 10.1038/Nrd3430 |
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| 2011 |
Gonon F, Bezard E, Boraud T. Misrepresentation of neuroscience data might give rise to misleading conclusions in the media: the case of attention deficit hyperactivity disorder. Plos One. 6: e14618. PMID 21297951 DOI: 10.1371/Journal.Pone.0014618 |
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| 2011 |
Leger F, Fernagut PO, Canron MH, Léoni S, Vital C, Tison F, Bezard E, Vital A. Protein aggregation in the aging retina. Journal of Neuropathology and Experimental Neurology. 70: 63-8. PMID 21157377 DOI: 10.1097/Nen.0B013E31820376Cc |
0.622 |
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| 2010 |
Fernagut PO, Li Q, Dovero S, Chan P, Wu T, Ravenscroft P, Hill M, Chen Z, Bezard E. Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys. Plos One. 5: e14053. PMID 21124922 DOI: 10.1371/Journal.Pone.0014053 |
0.806 |
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| 2010 |
Fasano S, Bezard E, D'Antoni A, Francardo V, Indrigo M, Qin L, Doveró S, Cerovic M, Cenci MA, Brambilla R. Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia. Proceedings of the National Academy of Sciences of the United States of America. 107: 21824-9. PMID 21115823 DOI: 10.1073/Pnas.1012071107 |
0.333 |
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| 2010 |
Barraud Q, Obeid I, Aubert I, Barrière G, Contamin H, McGuire S, Ravenscroft P, Porras G, Tison F, Bezard E, Ghorayeb I. Neuroanatomical study of the A11 diencephalospinal pathway in the non-human primate. Plos One. 5: e13306. PMID 20967255 DOI: 10.1371/Journal.Pone.0013306 |
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| 2010 |
Barroso-Chinea P, Bezard E. Basal Ganglia circuits underlying the pathophysiology of levodopa-induced dyskinesia. Frontiers in Neuroanatomy. 4. PMID 20890450 DOI: 10.3389/fnana.2010.00131 |
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| 2010 |
Rylander D, Parent M, O'Sullivan SS, Dovero S, Lees AJ, Bezard E, Descarries L, Cenci MA. Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia. Annals of Neurology. 68: 619-28. PMID 20882603 DOI: 10.1002/Ana.22097 |
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| 2010 |
Fernagut PO, Barraud Q, Bezard E, Ghorayeb I, Tison F. Metabolic activity of the subthalamic nucleus in a primate model of L-dopa-unresponsive parkinsonism. Neurological Research. 32: 1050-3. PMID 20810027 DOI: 10.1179/016164110X12807570509934 |
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| 2010 |
Santini E, Sgambato-Faure V, Li Q, Savasta M, Dovero S, Fisone G, Bezard E. Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesia. Plos One. 5: e12322. PMID 20808799 DOI: 10.1371/Journal.Pone.0012322 |
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| 2010 |
Rylander D, Iderberg H, Li Q, Dekundy A, Zhang J, Li H, Baishen R, Danysz W, Bezard E, Cenci MA. A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys. Neurobiology of Disease. 39: 352-61. PMID 20452425 DOI: 10.1016/J.Nbd.2010.05.001 |
0.437 |
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| 2010 |
Ahmed MR, Berthet A, Bychkov E, Porras G, Li Q, Bioulac BH, Carl YT, Bloch B, Kook S, Aubert I, Dovero S, Doudnikoff E, Gurevich VV, Gurevich EV, Bezard E. Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson's disease. Science Translational Medicine. 2: 28ra28. PMID 20410529 DOI: 10.1126/Scitranslmed.3000664 |
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| 2010 |
Storvik M, Arguel MJ, Schmieder S, Delerue-Audegond A, Li Q, Qin C, Vital A, Bioulac B, Gross CE, Wong G, Nahon JL, Bezard E. Genes regulated in MPTP-treated macaques and human Parkinson's disease suggest a common signature in prefrontal cortex. Neurobiology of Disease. 38: 386-94. PMID 20206263 DOI: 10.1016/J.Nbd.2010.02.008 |
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| 2010 |
Bezard E. Treating Parkinson's disease: preserve the spines! (Commentary on Soderstrom et al.). The European Journal of Neuroscience. 31: 477. PMID 20105227 DOI: 10.1111/j.1460-9568.2010.07117.x |
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| 2010 |
Silverdale MA, Kobylecki C, Hallett PJ, Li Q, Dunah AW, Ravenscroft P, Bezard E, Brotchie JM. Synaptic recruitment of AMPA glutamate receptor subunits in levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate. Synapse (New York, N.Y.). 64: 177-80. PMID 19852073 DOI: 10.1002/syn.20739 |
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| 2010 |
Bezard E, Porras G, Blesa J, Obeso JA. Chapter 37 - Compensatory Mechanisms in Experimental and Human Parkinsonism: Potential for New Therapies Handbook of Behavioral Neuroscience. 20: 641-652. DOI: 10.1016/B978-0-12-374767-9.00037-8 |
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| 2009 |
Berthet A, Bezard E. Dopamine receptors and L-dopa-induced dyskinesia. Parkinsonism & Related Disorders. 15: S8-12. PMID 20123563 DOI: 10.1016/S1353-8020(09)70827-2 |
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| 2009 |
Guigoni C, Bezard E. Involvement of canonical and non-canonical D1 dopamine receptor signalling pathways in L-dopa-induced dyskinesia. Parkinsonism & Related Disorders. 15: S64-7. PMID 20083011 DOI: 10.1016/S1353-8020(09)70783-7 |
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| 2009 |
Voon V, Fernagut PO, Wickens J, Baunez C, Rodriguez M, Pavon N, Juncos JL, Obeso JA, Bezard E. Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders. The Lancet. Neurology. 8: 1140-9. PMID 19909912 DOI: 10.1016/S1474-4422(09)70287-X |
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| 2009 |
Rodriguez-Oroz MC, Jahanshahi M, Krack P, Litvan I, Macias R, Bezard E, Obeso JA. Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms. The Lancet. Neurology. 8: 1128-39. PMID 19909911 DOI: 10.1016/S1474-4422(09)70293-5 |
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| 2009 |
Barraud Q, Lambrecq V, Forni C, McGuire S, Hill M, Bioulac B, Balzamo E, Bezard E, Tison F, Ghorayeb I. Sleep disorders in Parkinson's disease: the contribution of the MPTP non-human primate model. Experimental Neurology. 219: 574-82. PMID 19635479 DOI: 10.1016/J.Expneurol.2009.07.019 |
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| 2009 |
Vital A, Fernagut PO, Canron MH, Joux J, Bezard E, Martin-Negrier ML, Vital C, Tison F. The nigrostriatal pathway in Creutzfeldt-Jakob disease. Journal of Neuropathology and Experimental Neurology. 68: 809-15. PMID 19535991 DOI: 10.1097/Nen.0B013E3181Abdae8 |
0.705 |
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| 2009 |
Reese R, Charron G, Nadjar A, Aubert I, Thiolat ML, Hamann M, Richter A, Bezard E, Meissner WG. High frequency stimulation of the entopeduncular nucleus sets the cortico-basal ganglia network to a new functional state in the dystonic hamster. Neurobiology of Disease. 35: 399-405. PMID 19501651 DOI: 10.1016/j.nbd.2009.05.022 |
0.304 |
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| 2009 |
Berton O, Guigoni C, Li Q, Bioulac BH, Aubert I, Gross CE, Dileone RJ, Nestler EJ, Bezard E. Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease. Biological Psychiatry. 66: 554-61. PMID 19481198 DOI: 10.1016/J.Biopsych.2009.04.005 |
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| 2009 |
Berthet A, Porras G, Doudnikoff E, Stark H, Cador M, Bezard E, Bloch B. Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of L-DOPA-induced dyskinesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4829-35. PMID 19369551 DOI: 10.1523/Jneurosci.5884-08.2009 |
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| 2009 |
Schuster S, Doudnikoff E, Rylander D, Berthet A, Aubert I, Ittrich C, Bloch B, Cenci MA, Surmeier DJ, Hengerer B, Bezard E. Antagonizing L-type Ca2+ channel reduces development of abnormal involuntary movement in the rat model of L-3,4-dihydroxyphenylalanine-induced dyskinesia. Biological Psychiatry. 65: 518-26. PMID 18947822 DOI: 10.1016/J.Biopsych.2008.09.008 |
0.41 |
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| 2009 |
Nadjar A, Gerfen CR, Bezard E. Priming for l-dopa-induced dyskinesia in Parkinson's disease: a feature inherent to the treatment or the disease? Progress in Neurobiology. 87: 1-9. PMID 18938208 DOI: 10.1016/j.pneurobio.2008.09.013 |
0.477 |
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| 2009 |
Nadjar A, Berton O, Guo S, Leneuve P, Dovero S, Diguet E, Tison F, Zhao B, Holzenberger M, Bezard E. IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP. Neurobiology of Aging. 30: 2021-30. PMID 18394756 DOI: 10.1016/j.neurobiolaging.2008.02.009 |
0.686 |
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| 2009 |
Barraud Q, Lambrecq V, Forni C, Balzamo E, McGuire S, Hill M, Bioulac B, Bezard E, Tison F, Ghorayeb I. P3.172 Sleep disorders in Parkinson's disease: the contribution of the MPTP non-human primate model Parkinsonism & Related Disorders. 15. DOI: 10.1016/S1353-8020(09)70736-9 |
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| 2009 |
Rylander D, Li Q, Dekundy A, Li H, Baishen R, Danysz W, Bezard E, Cenci A. P2.157 Metabotropic glutamate receptor type 5 (mGluR5) antagonists improve L-DOPA-induced-dyskinesia in both rat and macaque models of Parkinson's disease Parkinsonism & Related Disorders. 15: S132. DOI: 10.1016/S1353-8020(09)70508-5 |
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| 2009 |
Hill M, Decamp E, Bezard E, Li Q, Schneider J, Crossman A. P2.010 Progressive MPTP non-human primate models that recapitulate non-motor symptoms of Parkinson's disease Parkinsonism & Related Disorders. 15: S90-S91. DOI: 10.1016/S1353-8020(09)70361-X |
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| 2009 |
Schneider JS, Decamp E, Hill M, Bezard E, Crossman A, Murphy B, Mocaer E, Thomasson-Perret N. P4-342: Effects of the novel histamine H3 receptor antagonist S 38093 in a non-human primate model of cognitive dysfunction Alzheimer's & Dementia. 5: e31-e31. DOI: 10.1016/j.jalz.2009.07.140 |
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| 2008 |
Muñoz A, Li Q, Gardoni F, Marcello E, Qin C, Carlsson T, Kirik D, Di Luca M, Björklund A, Bezard E, Carta M. Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia. Brain : a Journal of Neurology. 131: 3380-94. PMID 18952677 DOI: 10.1093/Brain/Awn235 |
0.374 |
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| 2008 |
Pioli EY, Meissner W, Sohr R, Gross CE, Bezard E, Bioulac BH. Differential behavioral effects of partial bilateral lesions of ventral tegmental area or substantia nigra pars compacta in rats. Neuroscience. 153: 1213-24. PMID 18455318 DOI: 10.1016/j.neuroscience.2008.01.084 |
0.795 |
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| 2008 |
Schuster S, Nadjar A, Guo JT, Li Q, Ittrich C, Hengerer B, Bezard E. The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4311-6. PMID 18434508 DOI: 10.1523/JNEUROSCI.4720-07.2008 |
0.438 |
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| 2008 |
Nicholas AP, Lubin FD, Hallett PJ, Vattem P, Ravenscroft P, Bezard E, Zhou S, Fox SH, Brotchie JM, Sweatt JD, Standaert DG. Striatal histone modifications in models of levodopa-induced dyskinesia. Journal of Neurochemistry. 106: 486-94. PMID 18410512 DOI: 10.1111/j.1471-4159.2008.05417.x |
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| 2008 |
Scholz B, Svensson M, Alm H, Sköld K, Fälth M, Kultima K, Guigoni C, Doudnikoff E, Li Q, Crossman AR, Bezard E, Andrén PE. Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure. Plos One. 3: e1589. PMID 18270577 DOI: 10.1371/Journal.Pone.0001589 |
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| 2008 |
Scheller D, Stichel-Gunkel C, Lübbert H, Porras G, Ravenscroft P, Hill M, Bezard E. Neuroprotective effects of rotigotine in the acute MPTP-lesioned mouse model of Parkinson's disease. Neuroscience Letters. 432: 30-4. PMID 18162314 DOI: 10.1016/j.neulet.2007.12.001 |
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| 2008 |
Porras G, Bezard E. Preclinical development of gene therapy for Parkinson's disease. Experimental Neurology. 209: 72-81. PMID 17904121 DOI: 10.1016/j.expneurol.2007.08.003 |
0.376 |
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| 2007 |
Gold SJ, Hoang CV, Potts BW, Porras G, Pioli E, Kim KW, Nadjar A, Qin C, LaHoste GJ, Li Q, Bioulac BH, Waugh JL, Gurevich E, Neve RL, Bezard E. RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14338-48. PMID 18160641 DOI: 10.1523/Jneurosci.4223-07.2007 |
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| 2007 |
Belujon P, Bezard E, Taupignon A, Bioulac B, Benazzouz A. Noradrenergic modulation of subthalamic nucleus activity: behavioral and electrophysiological evidence in intact and 6-hydroxydopamine-lesioned rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9595-606. PMID 17804620 DOI: 10.1523/JNEUROSCI.2583-07.2007 |
0.707 |
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| 2007 |
Guo S, Yan J, Yang T, Yang X, Bezard E, Zhao B. Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson's disease through inhibition of ROS-NO pathway. Biological Psychiatry. 62: 1353-62. PMID 17624318 DOI: 10.1016/j.biopsych.2007.04.020 |
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| 2007 |
Meissner W, Guigoni C, Cirilli L, Garret M, Bioulac BH, Gross CE, Bezard E, Benazzouz A. Impact of chronic subthalamic high-frequency stimulation on metabolic basal ganglia activity: a 2-deoxyglucose uptake and cytochrome oxidase mRNA study in a macaque model of Parkinson's disease. The European Journal of Neuroscience. 25: 1492-500. PMID 17425575 DOI: 10.1111/J.1460-9568.2007.05406.X |
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| 2007 |
Guigoni C, Doudnikoff E, Li Q, Bloch B, Bezard E. Altered D(1) dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates. Neurobiology of Disease. 26: 452-63. PMID 17350277 DOI: 10.1016/J.Nbd.2007.02.001 |
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| 2007 |
Pasquereau B, Nadjar A, Arkadir D, Bezard E, Goillandeau M, Bioulac B, Gross CE, Boraud T. Shaping of motor responses by incentive values through the basal ganglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1176-83. PMID 17267573 DOI: 10.1523/Jneurosci.3745-06.2007 |
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|
| 2007 |
Scheller D, Chan P, Li Q, Wu T, Zhang R, Guan L, Ravenscroft P, Guigoni C, Crossman AR, Hill M, Bezard E. Rotigotine treatment partially protects from MPTP toxicity in a progressive macaque model of Parkinson's disease. Experimental Neurology. 203: 415-22. PMID 17045989 DOI: 10.1016/J.Expneurol.2006.08.026 |
0.742 |
|
| 2007 |
Aubert I, Guigoni C, Li Q, Dovero S, Bioulac BH, Gross CE, Crossman AR, Bloch B, Bezard E. Enhanced preproenkephalin-B-derived opioid transmission in striatum and subthalamic nucleus converges upon globus pallidus internalis in L-3,4-dihydroxyphenylalanine-induced dyskinesia. Biological Psychiatry. 61: 836-44. PMID 16950226 DOI: 10.1016/J.Biopsych.2006.06.038 |
0.784 |
|
| 2007 |
Schuster S, Nadjar A, Guo J, Li Q, Ittrich C, Hengerer B, Bezard E. 2.508 The HMG-CoA reductase inhibitor lovastatin reduces incidence of L-Dopa-induced abnormal involuntary movements in experimental Parkinson's disease Parkinsonism & Related Disorders. 13: S144. DOI: 10.1016/S1353-8020(08)70782-X |
0.413 |
|
| 2007 |
Bezard E, Gold S, Hoang C, Porras G, Waugh J, Neve R. 2.502 RGS9−2 negatively modulates L-dopa-induced dyskinesia in experimental Parkinson's disease Parkinsonism & Related Disorders. 13: S143. DOI: 10.1016/S1353-8020(08)70776-4 |
0.429 |
|
| 2007 |
Bezard E, Berton O, Guigoni C, Dovero S, Kumar A, McClung C, DiLeone R, Nestler E. 2.501 Role of DeltaFosB in the development of L-DOPA-induced dyskinesia in a non-human primate model of Parkinson's disease Parkinsonism & Related Disorders. 13: S142. DOI: 10.1016/S1353-8020(08)70775-2 |
0.437 |
|
| 2006 |
Kultima K, Scholz B, Alm H, Sköld K, Svensson M, Crossman AR, Bezard E, Andrén PE, Lönnstedt I. Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: a proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGE. Bmc Bioinformatics. 7: 475. PMID 17067368 DOI: 10.1186/1471-2105-7-475 |
0.694 |
|
| 2006 |
Schapira AH, Bezard E, Brotchie J, Calon F, Collingridge GL, Ferger B, Hengerer B, Hirsch E, Jenner P, Le Novère N, Obeso JA, Schwarzschild MA, Spampinato U, Davidai G. Novel pharmacological targets for the treatment of Parkinson's disease. Nature Reviews. Drug Discovery. 5: 845-54. PMID 17016425 DOI: 10.1038/Nrd2087 |
0.757 |
|
| 2006 |
Li Q, Zhao D, Bezard E. Traditional Chinese medicine for Parkinson's disease: a review of Chinese literature. Behavioural Pharmacology. 17: 403-10. PMID 16940761 DOI: 10.1097/00008877-200609000-00006 |
0.405 |
|
| 2006 |
Bezard E. A call for clinically driven experimental design in assessing neuroprotection in experimental Parkinsonism. Behavioural Pharmacology. 17: 379-82. PMID 16940758 DOI: 10.1097/00008877-200609000-00003 |
0.332 |
|
| 2006 |
Leblois A, Meissner W, Bezard E, Bioulac B, Gross CE, Boraud T. Temporal and spatial alterations in GPi neuronal encoding might contribute to slow down movement in Parkinsonian monkeys. The European Journal of Neuroscience. 24: 1201-8. PMID 16930445 DOI: 10.1111/J.1460-9568.2006.04984.X |
0.805 |
|
| 2006 |
Nadjar A, Brotchie JM, Guigoni C, Li Q, Zhou SB, Wang GJ, Ravenscroft P, Georges F, Crossman AR, Bezard E. Phenotype of striatofugal medium spiny neurons in parkinsonian and dyskinetic nonhuman primates: a call for a reappraisal of the functional organization of the basal ganglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8653-61. PMID 16928853 DOI: 10.1523/Jneurosci.2582-06.2006 |
0.827 |
|
| 2006 |
Sokoloff P, Diaz J, Le Foll B, Guillin O, Leriche L, Bezard E, Gross C. The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders. Cns & Neurological Disorders Drug Targets. 5: 25-43. PMID 16613552 DOI: 10.2174/187152706784111551 |
0.68 |
|
| 2006 |
Bezard E, Gerlach I, Moratalla R, Gross CE, Jork R. 5-HT1A receptor agonist-mediated protection from MPTP toxicity in mouse and macaque models of Parkinson's disease. Neurobiology of Disease. 23: 77-86. PMID 16545572 DOI: 10.1016/J.Nbd.2006.02.003 |
0.747 |
|
| 2006 |
Meissner W, Ravenscroft P, Reese R, Harnack D, Morgenstern R, Kupsch A, Klitgaard H, Bioulac B, Gross CE, Bezard E, Boraud T. Increased slow oscillatory activity in substantia nigra pars reticulata triggers abnormal involuntary movements in the 6-OHDA-lesioned rat in the presence of excessive extracellular striatal dopamine. Neurobiology of Disease. 22: 586-98. PMID 16531050 DOI: 10.1016/j.nbd.2006.01.009 |
0.822 |
|
| 2006 |
Bezard E. S3 PATHOPHYSIOLOGY OF LEVODOPA-INDUCED DYSKINESIA IN PARKINSON??S DISEASE: OPPORTUNITIES FOR NOVEL TREATMENTS Behavioural Pharmacology. 17: 535. DOI: 10.1097/00008877-200609000-00022 |
0.416 |
|
| 2005 |
Ghorayeb I, Bezard E, Fernagut PO, Bioulac B, Tison F. [Animal models of parkinsonism]. Revue Neurologique. 161: 907-15. PMID 16365620 DOI: 10.1016/S0035-3787(05)85154-9 |
0.737 |
|
| 2005 |
Bassilana F, Mace N, Li Q, Stutzmann JM, Gross CE, Pradier L, Benavides J, Ménager J, Bezard E. Unraveling substantia nigra sequential gene expression in a progressive MPTP-lesioned macaque model of Parkinson's disease. Neurobiology of Disease. 20: 93-103. PMID 16137570 DOI: 10.1016/j.nbd.2005.02.005 |
0.71 |
|
| 2005 |
Guo S, Bezard E, Zhao B. Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway. Free Radical Biology & Medicine. 39: 682-95. PMID 16085186 DOI: 10.1016/j.freeradbiomed.2005.04.022 |
0.313 |
|
| 2005 |
Guigoni C, Dovero S, Aubert I, Li Q, Bioulac BH, Bloch B, Gurevich EV, Gross CE, Bezard E. Levodopa-induced dyskinesia in MPTP-treated macaques is not dependent on the extent and pattern of nigrostrial lesioning. The European Journal of Neuroscience. 22: 283-7. PMID 16029219 DOI: 10.1111/J.1460-9568.2005.04196.X |
0.809 |
|
| 2005 |
Guigoni C, Aubert I, Li Q, Gurevich VV, Benovic JL, Ferry S, Mach U, Stark H, Leriche L, HÃ¥kansson K, Bioulac BH, Gross CE, Sokoloff P, Fisone G, Gurevich EV, ... ... Bezard E, et al. Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors. Parkinsonism & Related Disorders. 11: S25-9. PMID 15885624 DOI: 10.1016/J.Parkreldis.2004.11.005 |
0.798 |
|
| 2005 |
Hallett PJ, Dunah AW, Ravenscroft P, Zhou S, Bezard E, Crossman AR, Brotchie JM, Standaert DG. Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease. Neuropharmacology. 48: 503-16. PMID 15755478 DOI: 10.1016/j.neuropharm.2004.11.008 |
0.82 |
|
| 2005 |
Guigoni C, Li Q, Aubert I, Dovero S, Bioulac BH, Bloch B, Crossman AR, Gross CE, Bezard E. Involvement of sensorimotor, limbic, and associative basal ganglia domains in L-3,4-dihydroxyphenylalanine-induced dyskinesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2102-7. PMID 15728850 DOI: 10.1523/Jneurosci.5059-04.2005 |
0.811 |
|
| 2005 |
Bezard E, Gross CE, Qin L, Gurevich VV, Benovic JL, Gurevich EV. L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain. Neurobiology of Disease. 18: 323-35. PMID 15686961 DOI: 10.1016/J.Nbd.2004.10.005 |
0.706 |
|
| 2005 |
Aubert I, Guigoni C, HÃ¥kansson K, Li Q, Dovero S, Barthe N, Bioulac BH, Gross CE, Fisone G, Bloch B, Bezard E. Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia. Annals of Neurology. 57: 17-26. PMID 15514976 DOI: 10.1002/Ana.20296 |
0.808 |
|
| 2005 |
Meissner W, Ravenscroft P, Reese R, Harnack D, Bioulac B, Gross C, Bezard E, Boraud T. L-DOPA induziert oszillierende Aktivität in der Substantia nigra Pars reticulata in einem Dyskinesiemodell der Ratte Aktuelle Neurologie. 32. DOI: 10.1055/s-2005-866657 |
0.795 |
|
| 2004 |
Pioli EY, Dovero S, Bioulac BH, Gross CE, Bezard E. Asymmetrically lesioned mesencephalon in healthy rodents: call for caution. Brain Research. 1022: 251-3. PMID 15353237 DOI: 10.1016/j.brainres.2004.07.014 |
0.817 |
|
| 2004 |
Pioli E, Sohr R, Meissner W, Barthe N, Gross CE, Bezard E, Bioulac BH. Partial bilateral mesencephalic lesions affect D1 but not D2 binding in both the striatum and cortex. Neurochemistry International. 45: 995-1004. PMID 15337298 DOI: 10.1016/j.neuint.2004.06.003 |
0.776 |
|
| 2004 |
Hill MP, Brotchie JM, Crossman AR, Bezard E, Michel A, Grimée R, Klitgaard H. Levetiracetam Interferes With the L-dopa priming process in MPTP-lesioned drug-naive marmosets. Clinical Neuropharmacology. 27: 171-7. PMID 15319703 DOI: 10.1097/01.wnf.0000135478.70905.3d |
0.794 |
|
| 2004 |
Diguet E, Gross CE, Tison F, Bezard E. Rise and fall of minocycline in neuroprotection: need to promote publication of negative results. Experimental Neurology. 189: 1-4. PMID 15296829 DOI: 10.1016/j.expneurol.2004.05.016 |
0.643 |
|
| 2004 |
Hsu A, Togasaki DM, Bezard E, Sokoloff P, Langston JW, Di Monte DA, Quik M. Effect of the D3 dopamine receptor partial agonist BP897 [N-[4-(4-(2-methoxyphenyl)piperazinyl)butyl]-2-naphthamide] on L-3,4-dihydroxyphenylalanine-induced dyskinesias and parkinsonism in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 311: 770-7. PMID 15226382 DOI: 10.1124/jpet.104.071142 |
0.412 |
|
| 2004 |
Diguet E, Fernagut PO, Wei X, Du Y, Rouland R, Gross C, Bezard E, Tison F. Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease. The European Journal of Neuroscience. 19: 3266-76. PMID 15217383 DOI: 10.1111/j.0953-816X.2004.03372.x |
0.796 |
|
| 2004 |
Meissner W, Hill MP, Tison F, Gross CE, Bezard E. Neuroprotective strategies for Parkinson's disease: conceptual limits of animal models and clinical trials. Trends in Pharmacological Sciences. 25: 249-53. PMID 15120490 DOI: 10.1016/j.tips.2004.03.003 |
0.681 |
|
| 2004 |
Guillin O, Griffon N, Diaz J, Le Foll B, Bezard E, Gross C, Lammers C, Stark H, Carroll P, Schwartz JC, Sokoloff P. Brain-derived neurotrophic factor and the plasticity of the mesolimbic dopamine pathway. International Review of Neurobiology. 59: 425-44. PMID 15006497 DOI: 10.1016/S0074-7742(04)59016-5 |
0.657 |
|
| 2004 |
Hill MP, Ravenscroft P, Bezard E, Crossman AR, Brotchie JM, Michel A, Grimée R, Klitgaard H. Levetiracetam potentiates the antidyskinetic action of amantadine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 310: 386-94. PMID 15004218 DOI: 10.1124/jpet.104.066191 |
0.822 |
|
| 2004 |
Bezard E, Hill MP, Crossman AR, Brotchie JM, Michel A, Grimée R, Klitgaard H. Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque. European Journal of Pharmacology. 485: 159-64. PMID 14757136 DOI: 10.1016/j.ejphar.2003.11.065 |
0.814 |
|
| 2004 |
Diguet E, Gross CE, Bezard E, Tison F, Stefanova N, Wenning GK. Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment. Neurology. 62: 158; author reply 15. PMID 14718729 DOI: 10.1212/Wnl.62.1.158 |
0.662 |
|
| 2004 |
Benazzouz A, Tai CH, Meissner W, Bioulac B, Bezard E, Gross C. High-frequency stimulation of both zona incerta and subthalamic nucleus induces a similar normalization of basal ganglia metabolic activity in experimental parkinsonism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 528-30. PMID 14715698 DOI: 10.1096/fj.03-0576fje |
0.809 |
|
| 2004 |
Meissner W, Harnack D, Hoessle N, Bezard E, Winter C, Morgenstern R, Kupsch A. High frequency stimulation of the entopeduncular nucleus has no effect on striatal dopaminergic transmission. Neurochemistry International. 44: 281-6. PMID 14602091 DOI: 10.1016/S0197-0186(03)00138-4 |
0.396 |
|
| 2004 |
Bezard E, Gross CE, Brotchie JM. Response to Obeso et al.: Presymptomatic compensation in Parkinson's disease is not dopamine-mediated Trends in Neurosciences. 27: 127-128. DOI: 10.1016/j.tins.2003.12.005 |
0.789 |
|
| 2003 |
Meissner W, Prunier C, Guilloteau D, Chalon S, Gross CE, Bezard E. Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease. Molecular Neurobiology. 28: 209-18. PMID 14709785 DOI: 10.1385/Mn:28:3:209 |
0.748 |
|
| 2003 |
Bezard E, Dovero S, Belin D, Duconger S, Jackson-Lewis V, Przedborski S, Piazza PV, Gross CE, Jaber M. Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10999-1007. PMID 14657156 DOI: 10.1523/Jneurosci.23-35-10999.2003 |
0.815 |
|
| 2003 |
Hill MP, Bezard E, McGuire SG, Crossman AR, Brotchie JM, Michel A, Grimée R, Klitgaard H. Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by L-dopa and ropinirole in the MPTP-lesioned marmoset. Movement Disorders : Official Journal of the Movement Disorder Society. 18: 1301-5. PMID 14639671 DOI: 10.1002/mds.10542 |
0.832 |
|
| 2003 |
Guillin O, Griffon N, Bezard E, Leriche L, Diaz J, Gross C, Sokoloff P. Brain-derived neurotrophic factor controls dopamine D3 receptor expression: therapeutic implications in Parkinson's disease. European Journal of Pharmacology. 480: 89-95. PMID 14623353 DOI: 10.1016/j.ejphar.2003.08.096 |
0.711 |
|
| 2003 |
Bezard E, Baufreton J, Owens G, Crossman AR, Dudek H, Taupignon A, Brotchie JM. Sonic hedgehog is a neuromodulator in the adult subthalamic nucleus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2337-8. PMID 14525941 DOI: 10.1096/fj.03-0291fje |
0.824 |
|
| 2003 |
Tai CH, Boraud T, Bezard E, Bioulac B, Gross C, Benazzouz A. Electrophysiological and metabolic evidence that high-frequency stimulation of the subthalamic nucleus bridles neuronal activity in the subthalamic nucleus and the substantia nigra reticulata. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1820-30. PMID 14519661 DOI: 10.1096/fj.03-0163com |
0.814 |
|
| 2003 |
Bezard E. Neuroprotection for Parkinson's disease: a call for clinically driven experimental design. The Lancet. Neurology. 2: 393. PMID 12849115 DOI: 10.1016/S1474-4422(03)00432-0 |
0.38 |
|
| 2003 |
Meissner W, Dovero S, Bioulac B, Gross CE, Bezard E. Compensatory regulation of striatal neuropeptide gene expression occurs before changes in metabolic activity of basal ganglia nuclei. Neurobiology of Disease. 13: 46-54. PMID 12758066 DOI: 10.1016/S0969-9961(03)00011-1 |
0.814 |
|
| 2003 |
Prunier C, Payoux P, Guilloteau D, Chalon S, Giraudeau B, Majorel C, Tafani M, Bezard E, Esquerré JP, Baulieu JL. Quantification of dopamine transporter by 123I-PE2I SPECT and the noninvasive Logan graphical method in Parkinson's disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 44: 663-70. PMID 12732666 |
0.316 |
|
| 2003 |
Bezard E, Gross CE, Brotchie JM. Presymptomatic compensation in Parkinson's disease is not dopamine-mediated. Trends in Neurosciences. 26: 215-21. PMID 12689773 DOI: 10.1016/S0166-2236(03)00038-9 |
0.834 |
|
| 2003 |
Pioli EY, Gross CE, Meissner W, Bioulac BH, Bezard E. The deafferented nonhuman primate is not a reliable model of intractable pain. Neurological Research. 25: 127-9. PMID 12635510 DOI: 10.1179/016164103101201274 |
0.749 |
|
| 2003 |
Marvanová M, Ménager J, Bezard E, Bontrop RE, Pradier L, Wong G. Microarray analysis of nonhuman primates: validation of experimental models in neurological disorders. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 929-31. PMID 12626435 DOI: 10.1096/fj.02-0681fje |
0.331 |
|
| 2003 |
Gross CE, Ravenscroft P, Dovero S, Jaber M, Bioulac B, Bezard E. Pattern of levodopa-induced striatal changes is different in normal and MPTP-lesioned mice. Journal of Neurochemistry. 84: 1246-55. PMID 12614325 DOI: 10.1046/j.1471-4159.2003.01600.x |
0.815 |
|
| 2002 |
Boraud T, Bezard E, Bioulac B, Gross CE. From single extracellular unit recording in experimental and human Parkinsonism to the development of a functional concept of the role played by the basal ganglia in motor control. Progress in Neurobiology. 66: 265-83. PMID 11960681 DOI: 10.1016/S0301-0082(01)00033-8 |
0.822 |
|
| 2001 |
Bezard E, Dovero S, Prunier C, Ravenscroft P, Chalon S, Guilloteau D, Crossman AR, Bioulac B, Brotchie JM, Gross CE. Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6853-61. PMID 11517273 DOI: 10.1523/Jneurosci.21-17-06853.2001 |
0.833 |
|
| 2001 |
Bezard E, Brotchie JM, Gross CE. Pathophysiology of levodopa-induced dyskinesia: potential for new therapies. Nature Reviews. Neuroscience. 2: 577-88. PMID 11484001 DOI: 10.1038/35086062 |
0.79 |
|
| 2001 |
Bezard E, Boraud T, Chalon S, Brotchie JM, Guilloteau D, Gross CE. Pallidal border cells: an anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey. Neuroscience. 103: 117-23. PMID 11311792 DOI: 10.1016/S0306-4522(00)00546-7 |
0.812 |
|
| 2001 |
Bezard E, Ravenscroft P, Gross CE, Crossman AR, Brotchie JM. Upregulation of striatal preproenkephalin gene expression occurs before the appearance of parkinsonian signs in 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine monkeys. Neurobiology of Disease. 8: 343-50. PMID 11300729 DOI: 10.1006/nbdi.2000.0375 |
0.84 |
|
| 2001 |
Bezard E, Crossman AR, Gross CE, Brotchie JM. Structures outside the basal ganglia may compensate for dopamine loss in the presymptomatic stages of Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1092-4. PMID 11292678 DOI: 10.1096/Fj.00-0637Fje |
0.831 |
|
| 2001 |
Boraud T, Bezard E, Bioulac B, Gross CE. Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey. Brain : a Journal of Neurology. 124: 546-57. PMID 11222455 DOI: 10.1093/Brain/124.3.546 |
0.819 |
|
| 2001 |
Bezard E, Dovero S, Prunier C, Ravenscroft P, Chalon S, Guilloteau D, Crossman AR, Bioulac B, Brotchie JM, Gross CE. Relationship between the Appearance of Symptoms and the Level of Nigrostriatal Degeneration in a Progressive 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Lesioned Macaque Model of Parkinson's Disease The Journal of Neuroscience. 21: 6853-6861. DOI: 10.1523/JNEUROSCI.21-17-06853.2001 |
0.812 |
|
| 2000 |
Bezard E, Dovero S, Imbert C, Boraud T, Gross CE. Spontaneous long-term compensatory dopaminergic sprouting in MPTP-treated mice. Synapse (New York, N.Y.). 38: 363-8. PMID 11020240 DOI: 10.1002/1098-2396(20001201)38:3<363::Aid-Syn16>3.0.Co;2-A |
0.812 |
|
| 2000 |
Bezard E, Jaber M, Gonon F, Boireau A, Bloch B, Gross CE. Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse. The European Journal of Neuroscience. 12: 2892-900. PMID 10971632 DOI: 10.1046/j.1460-9568.2000.00180.x |
0.72 |
|
| 2000 |
Ghorayeb I, Fernagut PO, Aubert I, Bezard E, Poewe W, Wenning GK, Tison F. Toward a primate model of L-dopa-unresponsive parkinsonism mimicking striatonigral degeneration. Movement Disorders : Official Journal of the Movement Disorder Society. 15: 531-6. PMID 10830420 DOI: 10.1002/1531-8257(200005)15:3<531::AID-MDS1017>3.0.CO;2-C |
0.465 |
|
| 2000 |
Boraud T, Bezard E, Bioulac B, Gross CE. Ratio of inhibited-to-activated pallidal neurons decreases dramatically during passive limb movement in the MPTP-treated monkey. Journal of Neurophysiology. 83: 1760-3. PMID 10712496 DOI: 10.1152/Jn.2000.83.3.1760 |
0.807 |
|
| 2000 |
Boraud T, Bezard E, Stutzmann JM, Bioulac B, Gross CE. Effects of riluzole on the electrophysiological activity of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey. Neuroscience Letters. 281: 75-8. PMID 10704746 DOI: 10.1016/S0304-3940(00)00780-1 |
0.834 |
|
| 2000 |
Imbert C, Bezard E, Guitraud S, Boraud T, Gross CE. Comparison of eight clinical rating scales used for the assessment of MPTP-induced parkinsonism in the Macaque monkey. Journal of Neuroscience Methods. 96: 71-6. PMID 10704673 DOI: 10.1016/S0165-0270(99)00184-3 |
0.753 |
|
| 1999 |
Bezard E, Brefel C, Tison F, Peyro-Saint-Paul H, Ladure P, Rascol O, Gross CE. Effect of the alpha 2 adrenoreceptor antagonist, idazoxan, on motor disabilities in MPTP-treated monkey. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 23: 1237-46. PMID 10581645 DOI: 10.1016/S0278-5846(99)00067-6 |
0.678 |
|
| 1999 |
Gross CE, Boraud T, Guehl D, Bioulac B, Bezard E. From experimentation to the surgical treatment of Parkinson's disease: prelude or suite in basal ganglia research? Progress in Neurobiology. 59: 509-32. PMID 10515666 DOI: 10.1016/S0301-0082(99)00015-5 |
0.814 |
|
| 1999 |
Guehl D, Bezard E, Dovero S, Boraud T, Bioulac B, Gross C. Trichloroethylene and parkinsonism: a human and experimental observation. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 6: 609-11. PMID 10457397 DOI: 10.1046/J.1468-1331.1999.650609.X |
0.819 |
|
| 1999 |
Bezard E, Boraud T, Nguyen JP, Velasco F, Keravel Y, Gross C. Cortical stimulation and epileptic seizure: a study of the potential risk in primates. Neurosurgery. 45: 346-50. PMID 10449080 DOI: 10.1097/00006123-199908000-00030 |
0.725 |
|
| 1999 |
Bezard E, Boraud T, Bioulac B, Gross CE. Involvement of the subthalamic nucleus in glutamatergic compensatory mechanisms. The European Journal of Neuroscience. 11: 2167-70. PMID 10336685 DOI: 10.1046/j.1460-9568.1999.00627.x |
0.83 |
|
| 1999 |
Bezard E, Gross CE, Fournier MC, Dovero S, Bloch B, Jaber M. Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter. Experimental Neurology. 155: 268-73. PMID 10072302 DOI: 10.1006/exnr.1998.6995 |
0.818 |
|
| 1998 |
Bezard E, Stutzmann JM, Imbert C, Boraud T, Boireau A, Gross CE. Riluzole delayed appearance of parkinsonian motor abnormalities in a chronic MPTP monkey model. European Journal of Pharmacology. 356: 101-4. PMID 9774238 DOI: 10.1016/S0014-2999(98)00537-8 |
0.792 |
|
| 1998 |
Bezard E, Imbert C, Gross CE. Experimental models of Parkinson's disease: from the static to the dynamic. Reviews in the Neurosciences. 9: 71-90. PMID 9711900 DOI: 10.1515/Revneuro.1998.9.2.71 |
0.73 |
|
| 1998 |
Bezard E, Bioulac B, Gross CE. Glutamatergic compensatory mechanisms in experimental parkinsonism. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 22: 609-23. PMID 9682276 DOI: 10.1016/S0278-5846(98)00030-X |
0.785 |
|
| 1998 |
Bezard E, Gross CE. Compensatory mechanisms in experimental and human parkinsonism: towards a dynamic approach. Progress in Neurobiology. 55: 93-116. PMID 9618745 DOI: 10.1016/S0301-0082(98)00006-9 |
0.734 |
|
| 1998 |
Boraud T, Bezard E, Guehl D, Bioulac B, Gross C. Effects of L-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey. Brain Research. 787: 157-60. PMID 9518590 DOI: 10.1016/S0006-8993(97)01563-1 |
0.812 |
|
| 1998 |
Bezard E, Boraud T, Imbert C, Dovero S, Bioulac B, Gross CE. Towards a dynamic approach of experimental parkinsonism Progress in Neuro-Psychopharmacology and Biological Psychiatry. 22: 1317-1329. DOI: 10.1016/S0278-5846(98)00072-4 |
0.826 |
|
| 1997 |
Bezard E, Dovero S, Bioulac B, Gross C. Effects of different schedules of MPTP administration on dopaminergic neurodegeneration in mice. Experimental Neurology. 148: 288-92. PMID 9398471 DOI: 10.1006/exnr.1997.6648 |
0.824 |
|
| 1997 |
Bezard E, Imbert C, Deloire X, Bioulac B, Gross CE. A chronic MPTP model reproducing the slow evolution of Parkinson's disease: evolution of motor symptoms in the monkey. Brain Research. 766: 107-12. PMID 9359593 DOI: 10.1016/S0006-8993(97)00531-3 |
0.822 |
|
| 1997 |
Bezard E, Dovero S, Bioulac B, Gross CE. Kinetics of nigral degeneration in a chronic model of MPTP-treated mice. Neuroscience Letters. 234: 47-50. PMID 9347943 DOI: 10.1016/S0304-3940(97)00663-0 |
0.83 |
|
| 1997 |
Bezard E, Boraud T, Bioulac B, Gross CE. Compensatory effects of glutamatergic inputs to the substantia nigra pars compacta in experimental parkinsonism. Neuroscience. 81: 399-404. PMID 9300430 DOI: 10.1016/S0306-4522(97)00226-1 |
0.842 |
|
| 1997 |
Beurrier C, Bezard E, Bioulac B, Gross C. Subthalamic stimulation elicits hemiballismus in normal monkey. Neuroreport. 8: 1625-9. PMID 9189903 DOI: 10.1097/00001756-199705060-00014 |
0.775 |
|
| 1997 |
Bezard E, Boraud T, Bioulac B, Gross CE. Presymptomatic revelation of experimental parkinsonism. Neuroreport. 8: 435-8. PMID 9080424 DOI: 10.1097/00001756-199701200-00012 |
0.841 |
|
| 1996 |
Boraud T, Bezard E, Bioulac B, Gross C. High frequency stimulation of the internal Globus Pallidus (GPi) simultaneously improves parkinsonian symptoms and reduces the firing frequency of GPi neurons in the MPTP-treated monkey. Neuroscience Letters. 215: 17-20. PMID 8880743 DOI: 10.1016/S0304-3940(96)12943-8 |
0.816 |
|
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