Philippe Sarret, PhD
Affiliations: | Physiology and Biophysics | Université de Sherbrooke, Sherbrooke, Québec, Canada |
Area:
Pain, Neurotensin receptors, NeurophysiologyWebsite:
http://sarretpainlab.comGoogle:
"Philippe Sarret"Mean distance: 17.91 (cluster 11)
Children
Sign in to add trainee| Louis Doré-Savard | grad student | Université de Sherbrooke | |
| Pascal Tetreault | grad student | 2013 | Université de Sherbrooke |
| Élie Besserer-Offroy | grad student | 2010-2018 | Université de Sherbrooke |
| David André Barrière | post-doc | 2012-2014 | Université de Sherbrooke |
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Publications
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| Breault É, Desgagné M, Neve J, et al. (2024) Multitarget Ligands that Comprise Opioid/Nonopioid Pharmacophores for Pain Management: Current State of the Science. Pharmacological Research. 107408 |
| Desgagné M, Chartier M, Lagard C, et al. (2024) Development of Macrocyclic Neurotensin Receptor Type 2 (NTS2) Opioid-Free Analgesics. Angewandte Chemie (International Ed. in English). e202405941 |
| Midavaine É, Brouillette RL, Théberge E, et al. (2024) Discovery of a CCR2-targeting pepducin therapy for chronic pain. Pharmacological Research. 107242 |
| Previti S, Desgagné M, Tourwé D, et al. (2022) Opening the amino acid toolbox for peptide-based NTS2-selective ligands as promising lead compounds for pain management. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3471 |
| Tran K, Sainsily X, Côté J, et al. (2022) Size-Reduced Macrocyclic Analogues of [Pyr]-apelin-13 Showing Negative Gα Bias Still Produce Prolonged Cardiac Effects. Journal of Medicinal Chemistry. 65: 531-551 |
| Chartier M, Desgagné M, Sousbie M, et al. (2021) Pharmacodynamic and pharmacokinetic profiles of a neurotensin receptor type 2 (NTS2) analgesic macrocyclic analog. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 141: 111861 |
| Michaelian N, Sadybekov A, Besserer-Offroy É, et al. (2021) Structural insights on ligand recognition at the human leukotriene B4 receptor 1. Nature Communications. 12: 2971 |
| Vivancos M, Fanelli R, Besserer-Offroy É, et al. (2021) Metabolically Stable Neurotensin Analogs Exert Potent and Long-Acting Analgesia Without Hypothermia. Behavioural Brain Research. 113189 |
| Chartier M, Desgagné M, Sousbie M, et al. (2021) Design, Structural Optimization, and Characterization of the First Selective Macrocyclic Neurotensin Receptor Type 2 Non-opioid Analgesic. Journal of Medicinal Chemistry |
| Besserer-Offroy É, Brouillette RL, Longpré JM, et al. (2020) Assessing Gα-signaling with IP-One: Single Plate Transfection and Assay Protocol for Cell-Based High-Throughput Assay. Bio-Protocol. 10: e3715 |