Timothy A. Springer
Affiliations: | Biological Chemistry & Molecular Pharmacology | Harvard Medical School, Boston, MA, United States |
Area:
ImmunologyWebsite:
http://www.fas.harvard.edu/~biophys/Timothy_Springer.htmGoogle:
"Timothy A. Springer"Bio:
http://www.nasonline.org/member-directory/members/3001708.html
https://bcmp.med.harvard.edu/faculty/springer
http://www.idi.harvard.edu/investigators_research/investigator/springer_lab/
http://labs.idi.harvard.edu/springer/pages/careernarrative
http://www.dfhcc.harvard.edu/membership/profile/member/1086/0/
Mean distance: 16.7 (cluster 11) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Jack L. Strominger | grad student | 1976 | Harvard (Chemistry Tree) | |
| (Detergent soluble products of HLA) | ||||
| César Milstein | post-doc | 1976-1977 | MRC-LMB (Chemistry Tree) | |
Children
Sign in to add trainee| Michael S. Diamond | grad student | ||
| Jongseong Kim | grad student | Harvard Medical School | |
| Michael L. Dustin | grad student | 1984- | Harvard Medical School (Microtree) |
| Mark A. Blenner | post-doc | Harvard Medical School (E-Tree) | |
| Joon Lee | post-doc | 2023- | (Chemistry Tree) |
| Tsan Sam Xiao | post-doc | 2001-2006 | Harvard Medical School (Chemistry Tree) |
| Xing CHEN | post-doc | 2007-2010 | Harvard Medical School (Chemistry Tree) |
| Mehmet Sen | post-doc | 2007-2015 | Harvard Medical School - Boston Children's Hospital (Chemistry Tree) |
Collaborators
Sign in to add collaborator| Joseph Mathew Kalappurakkal | collaborator | (Cell Biology Tree) |
BETA: Related publications
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Publications
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| Hao Y, Yan J, Fraser C, et al. (2024) Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits. Mabs. 16: 2365891 |
| Li J, Jo MH, Yan J, et al. (2024) Ligand binding initiates single-molecule integrin conformational activation. Cell |
| Jo MH, Li J, Jaumouillé V, et al. (2022) Single-molecule characterization of subtype-specific β1 integrin mechanics. Nature Communications. 13: 7471 |
| Jensen RK, Bajic G, Sen M, et al. (2021) Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b. Journal of Immunology (Baltimore, Md. : 1950) |
| Klug D, Goellner S, Kehrer J, et al. (2020) Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of TRAP. Elife. 9 |
| Klug D, Goellner S, Kehrer J, et al. (2020) Author response: Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of Plasmodium TRAP Elife |
| Jo MH, Li J, Springer TA, et al. (2020) Integrin-Dependent Difference in Cell Adhesion and Force Exertion Biophysical Journal. 118: 96a |
| Wang J, Su Y, Iacob RE, et al. (2019) General structural features that regulate integrin affinity revealed by atypical αVβ8. Nature Communications. 10: 5481 |
| Buß M, Tegtmeyer N, Schnieder J, et al. (2019) Specific high affinity interaction of Helicobacter pylori CagL with integrin α β promotes type IV secretion of CagA into human cells. The Febs Journal |
| Jiang Y, Fu H, Springer TA, et al. (2019) Electrostatic Steering Enables Flow-Activated von Willebrand Factor to Bind Platelet Glycoprotein, Revealed by Single-Molecule Stretching and Imaging. Journal of Molecular Biology |