DeannaLee M. Beauvais, Ph.D.

Affiliations: 
2005 University of Wisconsin, Madison, Madison, WI 
Area:
Mechanisms by which the syndecan family of cell surface receptors regulate cell growth, adhesion, and migration
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"DeannaLee Beauvais"
Mean distance: 17.64 (cluster 28)
 
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Alan C. Rapraeger grad student 2005 UW Madison
 (Syndecan-1 regulates alpha(v)beta(3) and alpha(v)beta(5) integrin activity via the ectodomain of its core protein.)
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Publications

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Stueven NA, Beauvais DM, Hu R, et al. (2023) Inhibiting IGF1R-mediated Survival Signaling in Head and Neck Cancer with the Peptidomimetic SSTN. Cancer Research Communications. 3: 97-108
Beauvais DM, Nelson SE, Adams KM, et al. (2022) Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression. The Journal of Biological Chemistry. 102029
Jung O, Beauvais DM, Adams KM, et al. (2019) VLA-4 phosphorylation during tumor and immune cell migration relies on its coupling to VEGFR2 and CXCR4 by syndecan-1. Journal of Cell Science
Beauvais DM, Jung O, Yang Y, et al. (2016) Syndecan-1 (CD138) suppresses apoptosis in multiple myeloma by activating IGF1 receptor: prevention by synstatinIGF1R inhibits tumor growth. Cancer Research
Wang H, Jin H, Beauvais DM, et al. (2014) Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with α6β4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival. The Journal of Biological Chemistry. 289: 30318-32
Rapraeger AC, Ell BJ, Roy M, et al. (2013) Vascular endothelial-cadherin stimulates syndecan-1-coupled insulin-like growth factor-1 receptor and cross-talk between αVβ3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesis. The Febs Journal. 280: 2194-206
Beauvais DM, Rapraeger AC. (2010) Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation. Journal of Cell Science. 123: 3796-807
Beauvais DM, Ell BJ, McWhorter AR, et al. (2009) Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor. The Journal of Experimental Medicine. 206: 691-705
Beauvais DM, Ell BJ, McWhorter AR, et al. (2009) Syndecan-1 regulates αvβ3and αvβ5integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor The Journal of Cell Biology. 184: i12-i12
Beauvais DM, Ell BJ, McWhorter AR, et al. (2008) Synstatin, a Sdc1 peptide, blocks αvβ3-dependent angiogenesis Matrix Biology. 27: 12
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