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Alan C. Rapraeger, PhD, University of California Berkeley 1979

Affiliations: 
Pathology and Laboratory Medicine University of Wisconsin, Madison, Madison, WI 
Area:
Mechanisms by which the syndecan family of cell surface receptors regulate cell growth, adhesion, and migration
Website:
http://www.pathology.wisc.edu/faculty/bio.aspx?name=acrapraeger
Google:
"Alan Rapraeger"
Mean distance: 15.61 (cluster 28)
 
SNBCP

Children

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Charles Yeaman grad student 1986-1993 UW Madison (Cell Biology Tree)
Kyle J. McQuade grad student 2003 UW Madison
Brandon J. Burbach grad student 2004 UW Madison
Benjamin L Allen grad student 1998-2004 UW Madison
DeannaLee M. Beauvais grad student 2005 UW Madison
Yan Ji grad student 2008 UW Madison
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Publications

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Beauvais DM, Jung O, Yang Y, et al. (2016) Syndecan-1 (CD138) suppresses apoptosis in multiple myeloma by activating IGF1 receptor: prevention by synstatinIGF1R inhibits tumor growth. Cancer Research
Tan X, Lambert PF, Rapraeger AC, et al. (2016) Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications. Trends in Cell Biology
Wang H, Jin H, Rapraeger AC. (2015) Syndecan-1 and Syndecan-4 Capture Epidermal Growth Factor Receptor Family Members and the α3β1 Integrin Via Binding Sites in Their Ectodomains: NOVEL SYNSTATINS PREVENT KINASE CAPTURE AND INHIBIT α6β4-INTEGRIN-DEPENDENT EPITHELIAL CELL MOTILITY. The Journal of Biological Chemistry. 290: 26103-13
Wang H, Jin H, Beauvais DM, et al. (2014) Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with α6β4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival. The Journal of Biological Chemistry. 289: 30318-32
Rapraeger AC. (2013) Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1R-αvβ3 integrin complex in tumorigenesis and angiogenesis. The Febs Journal. 280: 2207-15
Rapraeger AC, Ell BJ, Roy M, et al. (2013) Vascular endothelial-cadherin stimulates syndecan-1-coupled insulin-like growth factor-1 receptor and cross-talk between αVβ3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesis. The Febs Journal. 280: 2194-206
Altemeier WA, Schlesinger SY, Buell CA, et al. (2012) Transmembrane and extracellular domains of syndecan-1 have distinct functions in regulating lung epithelial migration and adhesion. The Journal of Biological Chemistry. 287: 34927-35
Zhang Y, McKown RL, Raab RW, et al. (2011) Focus on molecules: syndecan-1. Experimental Eye Research. 93: 329-30
Ma P, Beck SL, Raab RW, et al. (2011) Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin (Journal of Cell Biology (2006) 174, 7, (1097-1106)) Journal of Cell Biology. 192: 365
Beauvais DM, Rapraeger AC. (2010) Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation. Journal of Cell Science. 123: 3796-807
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