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Alan C. Rapraeger, PhD, University of California Berkeley 1979

Pathology and Laboratory Medicine University of Wisconsin, Madison, Madison, WI 
Mechanisms by which the syndecan family of cell surface receptors regulate cell growth, adhesion, and migration
"Alan Rapraeger"
Mean distance: 15.61 (cluster 28)


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Charles Yeaman grad student 1986-1993 UW Madison (Cell Biology Tree)
Kyle J. McQuade grad student 2003 UW Madison
Brandon J. Burbach grad student 2004 UW Madison
Benjamin L Allen grad student 1998-2004 UW Madison
DeannaLee M. Beauvais grad student 2005 UW Madison
Yan Ji grad student 2008 UW Madison
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Beauvais DM, Jung O, Yang Y, et al. (2016) Syndecan-1 (CD138) suppresses apoptosis in multiple myeloma by activating IGF1 receptor: prevention by synstatinIGF1R inhibits tumor growth. Cancer Research
Tan X, Lambert PF, Rapraeger AC, et al. (2016) Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications. Trends in Cell Biology
Wang H, Jin H, Rapraeger AC. (2015) Syndecan-1 and Syndecan-4 Capture Epidermal Growth Factor Receptor Family Members and the α3β1 Integrin Via Binding Sites in Their Ectodomains: NOVEL SYNSTATINS PREVENT KINASE CAPTURE AND INHIBIT α6β4-INTEGRIN-DEPENDENT EPITHELIAL CELL MOTILITY. The Journal of Biological Chemistry. 290: 26103-13
Wang H, Jin H, Beauvais DM, et al. (2014) Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with α6β4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival. The Journal of Biological Chemistry. 289: 30318-32
Rapraeger AC. (2013) Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1R-αvβ3 integrin complex in tumorigenesis and angiogenesis. The Febs Journal. 280: 2207-15
Rapraeger AC, Ell BJ, Roy M, et al. (2013) Vascular endothelial-cadherin stimulates syndecan-1-coupled insulin-like growth factor-1 receptor and cross-talk between αVβ3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesis. The Febs Journal. 280: 2194-206
Altemeier WA, Schlesinger SY, Buell CA, et al. (2012) Transmembrane and extracellular domains of syndecan-1 have distinct functions in regulating lung epithelial migration and adhesion. The Journal of Biological Chemistry. 287: 34927-35
Zhang Y, McKown RL, Raab RW, et al. (2011) Focus on molecules: syndecan-1. Experimental Eye Research. 93: 329-30
Ma P, Beck SL, Raab RW, et al. (2011) Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin (Journal of Cell Biology (2006) 174, 7, (1097-1106)) Journal of Cell Biology. 192: 365
Beauvais DM, Rapraeger AC. (2010) Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation. Journal of Cell Science. 123: 3796-807
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