Bryan L. Roth
Affiliations: | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Psychopharmacology, 5-HT2A receptors, hallucinogensWebsite:
http://pdsp.med.unc.edu/Google:
"Bryan Roth"Mean distance: 13.85 (cluster 6) | S | N | B | C | P |
Cross-listing: PsychTree
Parents
Sign in to add mentor| Carmine J. Coscia | grad student | Saint Louis University | |
| Carmine Coscia | grad student | Saint Louis University School of Medicine (Chemistry Tree) | |
| Erminio Costa | post-doc | NIMH | |
| Roland D. Ciaranello | research scientist | Stanford |
Children
Sign in to add trainee| Reid H.J. Olsen | grad student | 2015- | UNC Chapel Hill |
| John A. Gray | grad student | 1999-2003 | Case Western Medical School |
| Zongqi Xia | grad student | 1999-2003 | Case Western Medical School |
| Anushree Bhatnagar | grad student | 2005 | Case Western Medical School |
| Vincent Setola | grad student | 2005 | Case Western |
| Douglas J. Sheffler | grad student | 1998-2006 | Case Western |
| Feng Yan | grad student | 2008 | Case Western |
| Atheir I. Abbas | grad student | 2004-2009 | Case Western |
| Sarah C. Rogan | grad student | 2011 | UNC Chapel Hill |
| Martilias Farrell | grad student | 2013 | UNC Chapel Hill |
| Daniel J. Urban | grad student | 2013 | UNC Chapel Hill |
| John A Allen | post-doc | 2008-2011 | University of North Carolina at Chapel Hill School of Medicine |
| Hyeong-Min Lee | post-doc | 2015 | University of North Carolina at Chapel Hill School of Medicine (Chemistry Tree) |
Collaborators
Sign in to add collaborator| C.J. Malanga | collaborator | 2013- | UNC Chapel Hill |
| Prem N Yadav | collaborator | 2007-2012 | UNC Chapel Hill |
BETA: Related publications
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Publications
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| Kim Y, Gumpper RH, Liu Y, et al. (2024) Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature |
| Lyu J, Kapolka N, Gumpper R, et al. (2023) AlphaFold2 structures template ligand discovery. Biorxiv : the Preprint Server For Biology |
| Schmitz G, Roth BL. (2023) G protein coupled receptors as targets for transformative neuropsychiatric therapeutics. American Journal of Physiology. Cell Physiology |
| Cao C, Roth BL. (2023) The structure, function, and pharmacology of MRGPRs. Trends in Pharmacological Sciences. 44: 237-251 |
| Wang Y, Zhuang Y, DiBerto JF, et al. (2023) Structures of the entire human opioid receptor family. Cell |
| Gumpper RH, Roth BL. (2023) SnapShot: Psychedelics and serotonin receptor signaling. Cell. 186: 232-232.e1 |
| Kaplan AL, Confair DN, Kim K, et al. (2022) Bespoke library docking for 5-HT receptor agonists with antidepressant activity. Nature |
| Cao C, Barros-Álvarez X, Zhang S, et al. (2022) Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD. Neuron |
| Schmitz GP, Jain MK, Slocum ST, et al. (2022) 5-HT SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics. Acs Chemical Neuroscience. 13: 2386-2398 |
| Zhang S, Chen H, Zhang C, et al. (2022) Inactive and active state structures template selective tools for the human 5-HT receptor. Nature Structural & Molecular Biology. 29: 677-687 |