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Bryan L. Roth

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Psychopharmacology, 5-HT2A receptors, hallucinogens
Website:
http://pdsp.med.unc.edu/
Google:
"Bryan Roth"
Mean distance: 13.85 (cluster 6)
 		SNBCP
Cross-listing: PsychTree

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Parents

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Carmine J. Coscia grad student Saint Louis University
Carmine Coscia grad student Saint Louis University School of Medicine (Chemistry Tree)
Erminio Costa post-doc NIMH
Roland D. Ciaranello research scientist Stanford

Children

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Reid H.J. Olsen grad student 2015- UNC Chapel Hill
John A. Gray grad student 1999-2003 Case Western Medical School
Zongqi Xia grad student 1999-2003 Case Western Medical School
Anushree Bhatnagar grad student 2005 Case Western Medical School
Vincent Setola grad student 2005 Case Western
Douglas J. Sheffler grad student 1998-2006 Case Western
Feng Yan grad student 2008 Case Western
Atheir I. Abbas grad student 2004-2009 Case Western
Sarah C. Rogan grad student 2011 UNC Chapel Hill
Martilias Farrell grad student 2013 UNC Chapel Hill
Daniel J. Urban grad student 2013 UNC Chapel Hill
John A Allen post-doc 2008-2011 University of North Carolina at Chapel Hill School of Medicine
Hyeong-Min Lee post-doc 2015 University of North Carolina at Chapel Hill School of Medicine (Chemistry Tree)

Collaborators

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C.J. Malanga collaborator 2013- UNC Chapel Hill
Prem N Yadav collaborator 2007-2012 UNC Chapel Hill
BETA: Related publications

Publications

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Gumpper RH, Jain MK, Kim K, et al. (2025) The structural diversity of psychedelic drug actions revealed. Nature Communications. 16: 2734
Wang C, Liu Y, Lanier M, et al. (2024) High-affinity agonists reveal recognition motifs for the MRGPRD GPCR. Cell Reports. 43: 114942
Kim Y, Gumpper RH, Liu Y, et al. (2024) Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature
Lyu J, Kapolka N, Gumpper R, et al. (2023) AlphaFold2 structures template ligand discovery. Biorxiv : the Preprint Server For Biology
Schmitz G, Roth BL. (2023) G protein coupled receptors as targets for transformative neuropsychiatric therapeutics. American Journal of Physiology. Cell Physiology
Cao C, Roth BL. (2023) The structure, function, and pharmacology of MRGPRs. Trends in Pharmacological Sciences. 44: 237-251
Wang Y, Zhuang Y, DiBerto JF, et al. (2023) Structures of the entire human opioid receptor family. Cell
Gumpper RH, Roth BL. (2023) SnapShot: Psychedelics and serotonin receptor signaling. Cell. 186: 232-232.e1
Kaplan AL, Confair DN, Kim K, et al. (2022) Bespoke library docking for 5-HT receptor agonists with antidepressant activity. Nature
Cao C, Barros-Álvarez X, Zhang S, et al. (2022) Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD. Neuron
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