Bryan L. Roth

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Psychopharmacology, 5-HT2A receptors, hallucinogens
Website:
http://pdsp.med.unc.edu/
Google:
"Bryan Roth"
Mean distance: 13.85 (cluster 6)
 
SNBCP
Cross-listing: PsychTree

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Publications

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Zhang S, Chen H, Zhang C, et al. (2022) Inactive and active state structures template selective tools for the human 5-HT receptor. Nature Structural & Molecular Biology. 29: 677-687
McClure-Begley TD, Roth BL. (2022) The promises and perils of psychedelic pharmacology for psychiatry. Nature Reviews. Drug Discovery
Levit Kaplan A, Strachan RT, Braz JM, et al. (2022) Structure-Based Design of a Chemical Probe Set for the 5-HT Serotonin Receptor. Journal of Medicinal Chemistry
Kolb P, Kenakin T, Alexander SPH, et al. (2022) Community Guidelines for GPCR Ligand Bias: IUPHAR Review XX. British Journal of Pharmacology
Xu P, Huang S, Mao C, et al. (2021) Structures of the human dopamine D3 receptor-G complexes. Molecular Cell
Barnes NM, Ahern GP, Becamel C, et al. (2021) International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function. Pharmacological Reviews. 73: 310-520
Kim K, Che T, Panova O, et al. (2020) Structure of a Hallucinogen-Activated Gq-Coupled 5-HT Serotonin Receptor. Cell. 182: 1574-1588.e19
Pottel J, Armstrong D, Zou L, et al. (2020) The activities of drug inactive ingredients on biological targets. Science (New York, N.Y.). 369: 403-413
Nagai Y, Miyakawa N, Takuwa H, et al. (2020) Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys. Nature Neuroscience
Olsen RHJ, DiBerto JF, English JG, et al. (2020) TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome. Nature Chemical Biology
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