Yong Ran

Affiliations: 
Neuroscience University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Aging & Memory Loss,Neurodegeneration Gamma-secretase, Signal Peptide Peptidase, Intramembrane Proteolysis
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"Yong Ran"
Mean distance: 106866
 
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Publications

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Lessard CB, Rodriguez E, Ladd TB, et al. (2019) Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells. The Journal of Biological Chemistry
Lessard CB, Malnik SL, Zhou Y, et al. (2018) High-affinity interactions and signal transduction between Aβ oligomers and TREM2. Embo Molecular Medicine
Moore BD, Martin J, de Mena L, et al. (2017) Short Aβ peptides attenuate Aβ42 toxicity in vivo. The Journal of Experimental Medicine
Ran Y, Hossain F, Pannuti A, et al. (2017) γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct. Embo Molecular Medicine
Xu G, Ran Y, Fromholt SE, et al. (2015) Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits. Acta Neuropathologica Communications. 3: 72
Park HJ, Ran Y, Jung JI, et al. (2015) The stress response neuropeptide CRF increases amyloid-β production by regulating γ-secretase activity. The Embo Journal. 34: 1674-86
Jung JI, Ran Y, Cruz PE, et al. (2014) Complex relationships between substrate sequence and sensitivity to alterations in γ-secretase processivity induced by γ-secretase modulators. Biochemistry. 53: 1947-57
Ran Y, Cruz PE, Ladd TB, et al. (2014) γ-Secretase processing and effects of γ-secretase inhibitors and modulators on long Aβ peptides in cells. The Journal of Biological Chemistry. 289: 3276-87
Golde TE, Ran Y, Felsenstein KM. (2012) Shifting a complex debate on γ-secretase cleavage and Alzheimer's disease. The Embo Journal. 31: 2237-9
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