Danielle A. Simmons

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
neuroinflammation, BDNF, Huntington's Disease
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"Danielle Simmons"
Mean distance: 14.29 (cluster 7)
 
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Parents

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Judy Stern research assistant 1991-1995 Rutgers, New Brunswick
Pauline Yahr grad student 1996-2001 UC Irvine
 (Projections and neurotransmitters of cells activated with ejaculation.)
Frank Longo research scientist 2008- Stanford
Gary Lynch research scientist 2001-2008 UC Irvine
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Publications

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Latif-Hernandez A, Yang T, Raymond-Butler R, et al. (2024) A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Latif-Hernandez A, Yang T, Raymond-Butler R, et al. (2023) A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model. Biorxiv : the Preprint Server For Biology
Simmons DA, Belichenko NP, Longo FM. (2023) Pharmacological Co-Activation of TrkB and TrkC Receptor Signaling Ameliorates Striatal Neuropathology and Motor Deficits in Mouse Models of Huntington's Disease. Journal of Huntington's Disease
Gonzalez S, McHugh TLM, Yang T, et al. (2021) Small molecule modulation of TrkB and TrkC neurotrophin receptors prevents cholinergic neuron atrophy in an Alzheimer's disease mouse model at an advanced pathological stage. Neurobiology of Disease. 105563
Simmons DA, Mills BD, Butler Iii RR, et al. (2021) Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington's Disease: Preclinical Evidence with the p75 Ligand LM11A-31. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics
Simmons DA, Lartey FM, Schüler E, et al. (2019) Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology
Boakye PA, Rancic V, Whitlock KH, et al. (2019) Receptor-dependence of BDNF Actions in Superficial Dorsal Horn; Relation to Central Sensitization and Actions of Macrophage Colony Stimulating Factor 1 (CSF-1). Journal of Neurophysiology
Simmons DA, James ML, Belichenko NP, et al. (2018) TSPO-PET Imaging Using [18F]PBR06 is a Potential Translatable Biomarker for Treatment Response in Huntington's Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31. Human Molecular Genetics
Simmons DA. (2017) Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington's Disease. Journal of Huntington's Disease. 6: 303-325
Simmons DA, Belichenko NP, Ford EC, et al. (2016) A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice. Human Molecular Genetics. 25: 4920-4938
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