Danielle A. Simmons
Affiliations: | Stanford University, Palo Alto, CA |
Area:
neuroinflammation, BDNF, Huntington's DiseaseGoogle:
"Danielle Simmons"Mean distance: 14.29 (cluster 7) | S | N | B | C | P |
Parents
Sign in to add mentorJudy Stern | research assistant | 1991-1995 | Rutgers, New Brunswick | |
Pauline Yahr | grad student | 1996-2001 | UC Irvine | |
(Projections and neurotransmitters of cells activated with ejaculation.) | ||||
Frank Longo | research scientist | 2008- | Stanford | |
Gary Lynch | research scientist | 2001-2008 | UC Irvine |
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Publications
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Latif-Hernandez A, Yang T, Raymond-Butler R, et al. (2024) A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association |
Latif-Hernandez A, Yang T, Raymond-Butler R, et al. (2023) A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model. Biorxiv : the Preprint Server For Biology |
Simmons DA, Belichenko NP, Longo FM. (2023) Pharmacological Co-Activation of TrkB and TrkC Receptor Signaling Ameliorates Striatal Neuropathology and Motor Deficits in Mouse Models of Huntington's Disease. Journal of Huntington's Disease |
Gonzalez S, McHugh TLM, Yang T, et al. (2021) Small molecule modulation of TrkB and TrkC neurotrophin receptors prevents cholinergic neuron atrophy in an Alzheimer's disease mouse model at an advanced pathological stage. Neurobiology of Disease. 105563 |
Simmons DA, Mills BD, Butler Iii RR, et al. (2021) Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington's Disease: Preclinical Evidence with the p75 Ligand LM11A-31. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics |
Simmons DA, Lartey FM, Schüler E, et al. (2019) Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology |
Boakye PA, Rancic V, Whitlock KH, et al. (2019) Receptor-dependence of BDNF Actions in Superficial Dorsal Horn; Relation to Central Sensitization and Actions of Macrophage Colony Stimulating Factor 1 (CSF-1). Journal of Neurophysiology |
Simmons DA, James ML, Belichenko NP, et al. (2018) TSPO-PET Imaging Using [18F]PBR06 is a Potential Translatable Biomarker for Treatment Response in Huntington's Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31. Human Molecular Genetics |
Simmons DA. (2017) Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington's Disease. Journal of Huntington's Disease. 6: 303-325 |
Simmons DA, Belichenko NP, Ford EC, et al. (2016) A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice. Human Molecular Genetics. 25: 4920-4938 |