Cecilia Canessa

Yale University School of Medicine, New Haven, CT 
ASIC channels
"Cecilia Canessa"
Mean distance: 20.64 (cluster 46)
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Chen Z, Kuenze G, Meiler J, et al. (2021) An arginine residue in the outer segment of hASIC1a TM1 affects both proton affinity and channel desensitization. The Journal of General Physiology. 153
Wu Y, Chen Z, Canessa C. (2019) A Mechanism for Desensitization of all Three Functional Mammalian Acid Sensing Ion Channels Biophysical Journal. 116: 36a
Li T, Yang Y, Canessa CM. (2014) A method for activation of endogenous acid-sensing ion channel 1a (ASIC1a) in the nervous system with high spatial and temporal precision. The Journal of Biological Chemistry. 289: 15441-8
Hernández-Díaz I, Giraldez T, Morales S, et al. (2013) Heterogeneous nuclear ribonucleoprotein A2/B1 is a tissue-specific aldosterone target gene with prominent induction in the rat distal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G122-31
Li T, Yang Y, Canessa CM. (2011) Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1. Nature Communications. 2: 399
Li T, Yang Y, Canessa C. (2011) D433 Does Not Determine Ion Selectivity in ASIC1 Biophysical Journal. 100: 25a
Li T, Yang Y, Canessa CM. (2010) Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation. The Journal of Biological Chemistry. 285: 22706-12
Li T, Yang Y, Canessa CM. (2010) Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel. American Journal of Physiology. Cell Physiology. 299: C66-73
Arteaga MF, Coric T, Straub C, et al. (2008) A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 4459-64
Coric T, Passamaneck YJ, Zhang P, et al. (2008) Simple chordates exhibit a proton-independent function of acid-sensing ion channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1914-23
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