David Ronald Brown
Affiliations: | University of Bath, Bath, England, United Kingdom |
Area:
Neurodegeneration, glia, prions, synculein, secretasesGoogle:
"David Brown"Mean distance: 16.41 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Max R. Bennett | grad student | 1986-1990 | University of Sydney | |
| (M.Sc., Ph.D.) | ||||
| Hans A. Kretzschmar | grad student | 1993-1997 | Universität Göttingen | |
Children
Sign in to add trainee| Cathryn L. Haigh | grad student | University of Bath | |
| Xiaoyan Wang | grad student | University of Bath | |
| Josephine A. Wright | grad student | University of Bath | |
| Kay M. Uppington | grad student | 2004-2008 | University of Bath |
| Sarah Fontaine | grad student | 2005-2008 | University of Bath |
| Paul Davies | grad student | 2005-2010 | University of Bath |
| Marcus Brazier | post-doc | 2004-2006 | University of Bath |
BETA: Related publications
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Publications
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| Greenwood EK, Angelova DM, Büchner HMI, et al. (2022) The AICD fragment of APP initiates a FoxO3a mediated response via FANCD2. Molecular and Cellular Neurosciences. 122: 103760 |
| McDowall JS, Ntai I, Honeychurch KC, et al. (2017) Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL. Molecular and Cellular Neurosciences |
| Pass R, Frudd K, Barnett JP, et al. (2015) Prion infection in cells is abolished by a mutated manganese transporter but shows no relation to zinc. Molecular and Cellular Neurosciences. 68: 186-93 |
| Goñi F, Mathiason CK, Yim L, et al. (2015) Mucosal immunization with an attenuated Salmonella vaccine partially protects white-tailed deer from chronic wasting disease. Vaccine. 33: 726-33 |
| Cichon AC, Brown DR. (2014) Nrf-2 regulation of prion protein expression is independent of oxidative stress. Molecular and Cellular Neurosciences. 63: 31-7 |
| Walsh KP, Minamide LS, Kane SJ, et al. (2014) Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons. Plos One. 9: e95995 |
| Brown DR. (2013) α-Synuclein as a ferrireductase. Biochemical Society Transactions. 41: 1513-7 |
| Wright JA, McHugh PC, Pan S, et al. (2013) Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level. Molecular and Cellular Neurosciences. 57: 33-41 |
| Younan ND, Sarell CJ, Davies P, et al. (2013) The cellular prion protein traps Alzheimer's Aβ in an oligomeric form and disassembles amyloid fibers. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1847-58 |
| McHugh PC, Wright JA, Williams RJ, et al. (2012) Prion protein expression alters APP cleavage without interaction with BACE-1. Neurochemistry International. 61: 672-80 |